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Journal Articles

Mutational Profile and Dynamics of PPM1D -Mutant Clones in the Spectrum of Myeloid Disorders

Jean Pegliasco, David Fandrei, Florence Pasquier, Nathalie Ibrahim, Maria Kfoury, Guillemette Imbert-De-Tremiolles, Nourhan Lizziek, Céline Berthon, Mael Heiblig, Delphine Lebon, Ambroise Marcais, Mathieu Meunier, Ahmad Aljijakli, Emilie Lemasle, Sylvain Chantepie, Cécile Pautas, Pierre-Yves Dumas, Stephanie Haiat, Cyril Quivoron, Ileana antony-Debre, Sophie Cotteret, Raphael Itzykson, Hervé Dombret, Nicolas Duployez, Nathalie Droin, Christophe Marzac, Elsa Bernard, Jean-Baptiste Micol
Journal: Blood
Blood (2023) 142 (Supplement 1): 4064.
https://doi.org/10.1182/blood-2023-189428
Published: 2023
Journal Articles

Hyperleukocytosis Increases the Risk of Early Relapses Independently of Genetics in AML

Raphaël Liévin, Nicolas Duployez, Loïc Vasseur, Juliette Lambert, Mael Heiblig, Mathilde Hunault, Claude Gardin, Stephane De Botton, Elise Fournier, Cecile Pautas, Christine Terré, Eric Delabesse, Norbert Ifrah, Arnaud Pigneux, Celli-Lebras Karine, Christian Recher, Claude Preudhomme, Herve Dombret, Raphael Itzykson
Journal: Blood
Blood (2023) 142 (Supplement 1): 4322.
https://doi.org/10.1182/blood-2023-173614
Published: 2023
Journal Articles

Gemtuzumab Ozogamicin for Patients with Newly Diagnosed CD33 Positive Acute Myeloid Leukemia: Results from a French Retrospective Observational Study

Juliette Lambert, Emmanuel Raffoux, Delphine Lebon, Thorsten Braun, Mael Heiblig, Alberto Santagostino, Karin Gogat-Marchant, Cécile Pautas
Journal: Blood
Blood (2023) 142 (Supplement 1): 2893.
https://doi.org/10.1182/blood-2023-179575
Published: 2023
Journal Articles

Venetoclax in Combination with Intermediate Doses of Cytarabine in Consolidation Phase for Acute Myeloid Leukemia Patients in First Complete Remission; Results of the Part 1 of the Phase 1/2 Multicentric Covenidac Study

Lauris Gastaud, Pierre Peterlin, Mathilde Hunault, Emmanuel Raffoux, Sarah Bertoli, Martin Carré, Cecile Pautas, Sylvain Chantepie, Juliette Lambert, Nicolas Duployez, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Norbert Vey, Arnaud Pigneux, Eric Delabesse, Claude Preudhomme, Adriana Plesa, Francois Vergez, Jean-François Hamel, Herve Dombret, Christian Recher
Journal: Blood
Blood (2023) 142 (Supplement 1): 4261.
https://doi.org/10.1182/blood-2023-173656
Published: 2023
Journal Articles

Current Results of Intensive Therapy in Younger Adults with Acute Myeloid Leukemia (AML): The Large Randomized French Backbone Intergroup (BIG)-1 Study on Behalf of the Filo, ALFA, and SFGM-TC Study Groups

Hunault-Berger Mathilde, Cécile Pautas, Sarah Bertoli, Pierre-Yves Dumas, Emmanuel Raffoux, Tony Marchand, Marie Anne Hospital, Mael Heiblig, Sylvain Chantepie, Martin Carré, Pierre Peterlin, Emilie Lemasle, Célestine Simand, Maria Pilar Gallego Hernanz, Anne Huynh, Edouard Forcade, Raynier Devillier, Stéphanie Nguyen Quoc, Nicolas Duployez, Isabelle Luquet, Dominique Penther, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Gerard Socié, Jean-Yves Cahn, Norbert Ifrah, Norbert Vey, Regis Peffault De Latour, Eric Delabesse, Claude Preudhomme, Jean-François Hamel, Arnaud Pigneux, Christian Recher, Hervé Dombret
Journal: Blood
Blood (2023) 142 (Supplement 1): 967.
https://doi.org/10.1182/blood-2023-179376
Published: 2023
Journal Articles

Gilteritinib Activity in Refractory or Relapsed FLT3 -Mutated Acute Myeloid Leukemia Patients Previously Treated By Intensive Chemotherapy and Midostaurin: A Study from the French AML Intergroup ALFA/Filo

Pierre-Yves Dumas, Emmanuel Raffoux, Emilie Berard, Sarah Bertoli, Marie Anne Hospital, Mael Heiblig, Yohan Desbrosses, Caroline Bonmati, Cecile Pautas, Juliette Lambert, Corentin Orvain, Anne Banos, Florence Pasquier, Pierre Peterlin, Tony Marchand, Madalina Uzunov, Jamilé Frayfer, Pascal Turlure, Thomas Cluzeau, Eric Jourdan, Chantal Himberlin, Emmanuelle Tavernier, Alban Villate, Stéphanie Haiat, Marie-Lorraine Chretien, Martin Carre, Sylvain Chantepie, Iona Vaida, Mathieu Wemeau, Safia Chebrek, Gaëlle Guillerm, Romain Guieze, Houria Debarri, Eve Gehlkopf, Kamel Laribi, Ambroise Marçais, Alberto Santagostino, Marie C Bene, Ariane C Mineur, Arnaud Pigneux, Herve Dombret, Christian Recher
Journal: Blood
Blood (2022) 140 (Supplement 1): 8996–8998.
https://doi.org/10.1182/blood-2022-159125
Published: 2022
Journal Articles

Prognostic Impact of Monoallelic Versus Biallelic TP53 Alterations in Intensively-Treated Adults AML Patients: A Retrospective Study from the ALFA Group

Laurène Fenwarth, Loïc Vasseur, Nicolas Duployez, Claude Gardin, Christine Terré, Juliette Lambert, Stéphane de Botton, Karine Celli-Lebras, Pascal Turlure, Thomas Cluzeau, Thorsten Braun, Xavier Thomas, Christian Recher, Sylvain Chantepie, Cécile Pautas, Hervé Dombret, Claude Preudhomme, Raphael Itzykson
Journal: Blood
Blood (2022) 140 (Supplement 1): 737–738.
https://doi.org/10.1182/blood-2022-163044
Published: 2022
Journal Articles

Retrospective Analysis of the Outcomes of Patients with Relapsed/Refractory Acute Myeloid Leukemia Included in a Patient Named Program of Gemtuzumab Ozogamicin

Juliette Lambert, Pierre Peterlin, Cecile Pautas, Emmanuel Raffoux, Denis Caillot, Ollivier Legrand, Magalie Joris, Anna Berceanu, Jean Valere Malfuson, Sylvain Chantepie, Marc Bernard, Lauris Gastaud, Arnaud Pigneux, Omar Benbrahim, Caroline Bonmati, Hunault-Berger Mathilde, Hervé Dombret, Philippe Rousselot, Sylvie Chevret, Sylvie Castaigne
Journal: Blood
Blood (2021) 138 (Supplement 1): 876.
https://doi.org/10.1182/blood-2021-145184
Published: 2021
Journal Articles

Replacing the Anthracycline By Gemtuzumab Ozogamicin in Older Patients with De Novo Standard-Risk Acute Myeloid Leukemia Treated Intensively - Results of the Randomized ALFA1401-Mylofrance 4 Study

Juliette Lambert, Jérôme Lambert, Emilie Lemasle, Magalie Joris, Sylvain Chantepie, Cecile Pautas, Xavier Thomas, Jean Valere Malfuson, Lauris Gastaud, Denis Caillot, Emmanuelle Tavernier, Pascal Turlure, Diana Carp, Celine Berthon, Olivier Legrand, Ambroise Marçais, Iona Vaida, Sarah Barbieux, Philippe Rousselot, Claude Gardin, Christine Terré, Nicolas Duployez, Claude Preudhomme, Karine Celli-Lebras, Sylvie Castaigne, Herve Dombret
Journal: Blood
Blood (2021) 138 (Supplement 1): 31.
https://doi.org/10.1182/blood-2021-145152
Published: 2021
Journal Articles

Genetic identification of patients with AML older than 60 years achieving long-term survival with intensive chemotherapy

CME Clinical Trials & Observations
Raphael Itzykson, Elise Fournier, Céline Berthon, Christoph Röllig, Thorsten Braun, Alice Marceau-Renaut, Cécile Pautas, Olivier Nibourel, Emilie Lemasle, Jean-Baptiste Micol, Lionel Adès, Delphine Lebon, Jean-Valère Malfuson, Lauris Gastaud, Laure Goursaud, Emmanuel Raffoux, Kevin-James Wattebled, Philippe Rousselot, Xavier Thomas, Sylvain Chantepie, Thomas Cluzeau, Hubert Serve, Nicolas Boissel, Christine Terré, Karine Celli-Lebras, Claude Preudhomme, Christian Thiede, Hervé Dombret, Claude Gardin, Nicolas Duployez
Journal: Blood
Blood (2021) 138 (7): 507–519.
https://doi.org/10.1182/blood.2021011103
Published: 2021
Includes: Supplemental data
Journal Articles

Prognostic significance of concurrent gene mutations in intensively treated patients with IDH -mutated AML: an ALFA study

CME Clinical Trials & Observations
Matthieu Duchmann, Jean-Baptiste Micol, Nicolas Duployez, Emmanuel Raffoux, Xavier Thomas, Jean-Pierre Marolleau, Thorsten Braun, Lionel Adès, Sylvain Chantepie, Emilie Lemasle, Céline Berthon, Jean-Valère Malfuson, Cécile Pautas, Juliette Lambert, Nicolas Boissel, Karine Celli-Lebras, Denis Caillot, Pascal Turlure, Norbert Vey, Arnaud Pigneux, Christian Recher, Christine Terré, Claude Gardin, Raphaël Itzykson, Claude Preudhomme, Hervé Dombret, Stéphane de Botton
Journal: Blood
Blood (2021) 137 (20): 2827–2837.
https://doi.org/10.1182/blood.2020010165
Published: 2021
Includes: Supplemental data
Journal Articles

A personalized approach to guide allogeneic stem cell transplantation in younger adults with acute myeloid leukemia

Clinical Trials & Observations
Laurène Fenwarth, Xavier Thomas, Stéphane de Botton, Nicolas Duployez, Jean-Henri Bourhis, Auriane Lesieur, Gael Fortin, Paul-Arthur Meslin, Ibrahim Yakoub-Agha, Pierre Sujobert, Pierre-Yves Dumas, Christian Récher, Delphine Lebon, Céline Berthon, Mauricette Michallet, Arnaud Pigneux, Stéphanie Nguyen, Sylvain Chantepie, Norbert Vey, Emmanuel Raffoux, Karine Celli-Lebras, Claude Gardin, Juliette Lambert, Jean-Valère Malfuson, Denis Caillot, Sébastien Maury, Benoît Ducourneau, Pascal Turlure, Emilie Lemasle, Cécile Pautas, Sylvie Chevret, Christine Terré, Nicolas Boissel, Gérard Socié, Hervé Dombret, Claude Preudhomme, Raphael Itzykson
Journal: Blood
Blood (2021) 137 (4): 524–532.
https://doi.org/10.1182/blood.2020005524
Published: 2021
Includes: Supplemental data
Journal Articles

Comparison of a Combination of Vosaroxin (VOS) and Intermediate-Dose Cytarabine (IDAC) with Idac for the Consolidation Therapy of Younger Patients with Favorable- and Intermediate-Risk Acute Myeloid Leukemia (AML) in First Complete Remission (CR): Preliminary Results of a Randomized Phase 2 R4-VOS Study of the French ALFA-Filo AML Intergroup

Norbert Vey, MD, Corentin Orvain, MD PhD, Christian Recher, MD PhD, Arnaud Pigneux, MD PhD, Marc Bernard, MD, Anne Banos, MD, Pierre Peterlin, MD, Sylvain Chantepie, MD, Xavier Thomas, MD PhD, Cecile Pautas, MD, Claude Gardin, Emilie Lemasle, MD, Emmanuel Raffoux, MD, Romain Guieze, MD, Chantal Himberlin, MD, Clémence Loiseau, MD, Amine Belhabri, MD, Isabelle Luquet, MD, Christine Terré, PharmD, PhD, Martin Carre, MD, Claude Preudhomme, MD PhD, Eric Delabesse, MD PhD, Karine Celli-Lebras, CRA, Ariane C Mineur, CRA, Jean-Francois Brasme, MD PhD, Jean Francois Hamel, MD, Hervé Dombret, MD, Mathilde Hunault, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10–11.
https://doi.org/10.1182/blood-2020-137032
Published: 2020
Journal Articles

Very Long Term Follow up a Phase II Study of Post-Remission Subcutaneous (SC) Azacitidine (AZA) in Patients with AML Post-MDS or Higher-Risk (HR) MDS

Amina Cherait, Thorsten Braun, MD PhD, Krimo Bouabdallah, MD, Denis Caillot, Agnès Guerci, MD PhD, Emmanuel Raffoux, MD, Jean Pierre Marolleau, Cecile Pautas, MD, Anne Banos, MD, Chantal Himberlin, MD, Anne Laure Taksin, Arnaud Pigneux, MD PhD, Xavier Thomas, MD PhD, Norbert Vey, MD, Sylvie Chevret, MDPhD, Herve Dombret, MD PhD, Fatiha Chermat, Lionel Ades, MDPhD, Claude Gardin, Pierre Fenaux, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–2.
https://doi.org/10.1182/blood-2020-137012
Published: 2020
Journal Articles

Mutational profile and benefit of gemtuzumab ozogamicin in acute myeloid leukemia

Clinical Trials & Observations Brief Report
Elise Fournier, Nicolas Duployez, Benoît Ducourneau, Emmanuel Raffoux, Pascal Turlure, Denis Caillot, Xavier Thomas, Alice Marceau-Renaut, Sylvain Chantepie, Jean-Valère Malfuson, Emilie Lemasle, Meyling Cheok, Karine Celli-Lebras, Estelle Guerin, Christine Terré, Juliette Lambert, Cécile Pautas, Hervé Dombret, Sylvie Castaigne, Claude Preudhomme, Nicolas Boissel
Journal: Blood
Blood (2020) 135 (8): 542–546.
https://doi.org/10.1182/blood.2019003471
Published: 2020
Includes: Supplemental data
Journal Articles

Acute Myeloid Leukemia and Antifungal Prophylaxis Era: Compliance of AML Centers, Invasive Fungal Infection (IFI) Classification, IFI Incidence and AML Outcomes from ALFA 2007- 02 Study

Mauricette Michallet, MD PhD, Mohamad Sobh, PharmD, Stephane Morisset, BioStat, Alexandre Deloire, CRA, Emmanuel Raffoux, MD, Stephane De Botton, Denis Caillot, MD, Sylvain Chantepie, MD, Stephane Girault, MD, Celine Berthon, MD, Sarah Bertoli, MD PhD, Stephane Lepretre, Thibaut Leguay, MD, Sylvie Castaigne, MD, Jean-Pierre Marolleau, MD PhD, Cecile Pautas, MD, Jean Valère Malfuson, MD, Norbert Vey, MD PhD, Lauris Gastaud, Felipe Suarez, MD PhD, Aline Schmidt, MD, Rémy Gressin, MD, Caroline Bonmati, MD, Karine Celli-Lebras, CRA, Mohamed El-Hamri, CRA, Patricia Ribaud, MD, Herve Dombret, MD PhD, Xavier Thomas, MD PhD, Anne Bergeron
Journal: Blood
Blood (2019) 134 (Supplement_1): 2618.
https://doi.org/10.1182/blood-2019-130642
Published: 2019
Journal Articles

Prognostic Significance of Concurrent Gene Mutations in Intensively Treated Patients with IDH1/2 Mutated AML

Matthieu Duchmann, Jean-Baptiste Micol, MD, Nicolas Duployez, PharmD, PhD, Emmanuel Raffoux, MD, Xavier Thomas, MD PhD, Jean-Pierre Marolleau, MD PhD, Thorsten Braun, MD, Lionel Ades, MD PhD, Sylvain Chantepie, MD, Emilie Lemasle, MD, Celine Berthon, MD PhD, Jean Valère Malfuson, MD, Cecile Pautas, MD, Juliette Lambert, MD, Nicolas Boissel, MD PhD, Karine Celli-Lebras, CRA, Denis Caillot, MD, Pascal Turlure, MD, Norbert Vey, MD PhD, Arnaud Pigneux, Christian Recher, MD PhD, Christine Terré, PharmD, PhD, Claude Gardin, Raphael Itzykson, MD PhD, Claude Preudhomme, PharmD, PhD, Herve Dombret, MD PhD, Stephane De Botton
Journal: Blood
Blood (2019) 134 (Supplement_1): 1416.
https://doi.org/10.1182/blood-2019-127082
Published: 2019
Journal Articles

Integrating ELN Criteria and a 'Knowledge Bank' Approach to Guide Allogeneic Stem Cell Transplantation (SCT) Indication in Younger Adults with Acute Myeloid Leukemia (AML): An Acute Leukemia French Association Study

Laurène Fenwarth, MD MSc, Raphael Itzykson, MD PhD, Stephane De Botton, MD PhD, Nicolas Duployez, PharmD, PhD, Pierre Sujobert, MD PhD, Céline Berthon, MD PhD, Arnaud Pigneux, Sylvain Chantepie, MD, Christian Recher, MD PhD, Emmanuel Raffoux, MD, Juliette Lambert, MD, Karine Celli-Lebras, CRA, Denis Caillot, MD, Benoit Ducourneau, PharmD, Pascal Turlure, MD, Emilie Lemasle, MD, Cecile Pautas, MD, Norbert Vey, MD PhD, Sylvie Chevret, MD PhD, Christine Terré, PharmD, PhD, Xavier Thomas, MD PhD, Claude Preudhomme, PharmD, PhD, Herve Dombret, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1423.
https://doi.org/10.1182/blood-2019-122468
Published: 2019
Journal Articles

Oncogenic Predictors of Outcome in Older AML Patients Treated Intensively. Analysis of the ALFA-1200 Trial

Raphael Itzykson, MD PhD, Elise Fournier, Thorsten Braun, MD PhD, Céline Berthon, MD PhD, Alice Marceau-Renaut, Cecile Pautas, Olivier Nibourel, Emilie Lemasle, MD, Nicolas Duployez, PharmD, PhD, Jean-Baptiste Micol, MD PhD, Lionel Ades, MD PhD, Jean-Pierre Marolleau, MD PhD, Jean Valère Malfuson, MD, Lauris Gastaud, Emmanuel Raffoux, MD, Philippe Rousselot, MD, Xavier Thomas, MD, Sylvain Chantepie, MD, Thomas Cluzeau, MDPhD, Benjamin Papoular, Nicolas Boissel, MD PhD, Christine Terré, PharmD, PhD, Karine Celli-Lebras, CRA, Herve Dombret, MD, Claude Gardin, Claude Preudhomme
Journal: Blood
Blood (2018) 132 (Supplement 1): 993.
https://doi.org/10.1182/blood-2018-99-111144
Published: 2018
Journal Articles

Outcomes Following Hematopoietic Stem Cell Transplantation in Patients Treated with Chemotherapy with or without Gemtuzumab Ozogamicin for Acute Myeloid Leukemia

Cécile Pautas, Emmanuel Raffoux, MD, Juliette Lambert, Ollivier Legrand, MD PhD, Rebecca J Benner, Erik R. Vandendries, MD PhD, Karïn Gogat, Hervé Dombret, MD, Sylvie Castaigne, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 28.
https://doi.org/10.1182/blood-2018-99-111251
Published: 2018