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Journal Articles

Nilotinib with or without cytarabine for Philadelphia-positive acute lymphoblastic leukemia

Clinical Trials & Observations
Yves Chalandon, Philippe Rousselot, Sylvie Chevret, Jean-Michel Cayuela, Rathana Kim, Françoise Huguet, Patrice Chevallier, Carlos Graux, Anne Thiebaut-Bertrand, Sylvain Chantepie, Xavier Thomas, Laure Vincent, Céline Berthon, Yosr Hicheri, Emmanuel Raffoux, Martine Escoffre-Barbe, Isabelle Plantier, Magalie Joris, Pascal Turlure, Florence Pasquier, Amine Belhabri, Gabrielle Roth Guepin, Sabine Blum, Michael Gregor, Marina Lafage-Pochitaloff, Julie Quessada, Véronique Lhéritier, Emmanuelle Clappier, Nicolas Boissel, Hervé Dombret
Journal: Blood
Blood (2024) 143 (23): 2363–2372.
https://doi.org/10.1182/blood.2023023502
Published: 2024
Includes: Supplemental data
Journal Articles

Outcomes for Children with High Risk Acute Myeloid Leukemia on the Myechild 01 International Phase III Clinical Trial

Andrew Moore, Shanna Maycock, Guy Leverger, Owen Smith, Andre Baruchel, Yves Bertrand, Phil Ancliff, Nicholas Heaney, Geoff Shenton, Arnaud Petit, Jean-Pierre Bourquin, Aimee Jackson, Anna Lawson, Persis Amrolia, Gerard Michel, Jean-Hugues Dalle, Marc Ansari, Hélène Lapillonne, Richard Dillon, Jelena Jovanovic, Christophe Roumier, Nicolas Duployez, Christine Harrison, Claire Schwab, Wendy Cuccuini, Marina Lafage-Pochitaloff, Paresh Vyas, Pierre Hirsch, Gareth Veal, Pam Kearns, Brenda Gibson
Journal: Blood
Blood (2023) 142 (Supplement 1): 730.
https://doi.org/10.1182/blood-2023-181593
Published: 2023
Journal Articles

PAX5 P80R mutation identifies a novel subtype of B-cell precursor acute lymphoblastic leukemia with favorable outcome

Marie Passet, Nicolas Boissel, François Sigaux, Colombe Saillard, Mario Bargetzi, Ibrahima Ba, Xavier Thomas, Carlos Graux, Yves Chalandon, Thibaut Leguay, Etienne Lengliné, Johanna Konopacki, Samuel Quentin, Eric Delabesse, Marina Lafage-Pochitaloff, Cédric Pastoret, Nathalie Grardel, Vahid Asnafi, Véronique Lhéritier, Jean Soulier, Hervé Dombret, Emmanuelle Clappier
Journal: Blood
Blood (2019) 133 (3): 280–284.
https://doi.org/10.1182/blood-2018-10-882142
Published: 2019
Includes: Supplemental data
Journal Articles

Impact of cytogenetic abnormalities in adults with Ph-negative B-cell precursor acute lymphoblastic leukemia

Clinical Trials & Observations
Marina Lafage-Pochitaloff, Laurence Baranger, Mathilde Hunault, Wendy Cuccuini, Christine Lefebvre, Audrey Bidet, Isabelle Tigaud, Virginie Eclache, Eric Delabesse, Chrystèle Bilhou-Nabéra, Christine Terré, Elise Chapiro, Nathalie Gachard, Marie-Joelle Mozziconacci, Geneviève Ameye, Sarah Porter, Nathalie Grardel, Marie C. Béné, Yves Chalandon, Carlos Graux, Françoise Huguet, Véronique Lhéritier, Norbert Ifrah, Hervé Dombret
Journal: Blood
Blood (2017) 130 (16): 1832–1844.
https://doi.org/10.1182/blood-2017-05-783852
Published: 2017
Includes: Supplemental data
Journal Articles

Dasatinib and low-intensity chemotherapy in elderly patients with Philadelphia chromosome–positive ALL

Clinical Trials & Observations
Philippe Rousselot, Marie Magdelaine Coudé, Nicola Gokbuget, Carlo Gambacorti Passerini, Sandrine Hayette, Jean-Michel Cayuela, Françoise Huguet, Thibaut Leguay, Patrice Chevallier, Celia Salanoubat, Caroline Bonmati, Magda Alexis, Mathilde Hunault, Sylvie Glaisner, Philippe Agape, Christian Berthou, Eric Jourdan, José Fernandes, Laurent Sutton, Anne Banos, Oumedaly Reman, Bruno Lioure, Xavier Thomas, Norbert Ifrah, Marina Lafage-Pochitaloff, Anne Bornand, Laure Morisset, Valérie Robin, Heike Pfeifer, Andre Delannoy, Josep Ribera, Renato Bassan, Marc Delord, Dieter Hoelzer, Herve Dombret, Oliver G. Ottmann
Journal: Blood
Blood (2016) 128 (6): 774–782.
https://doi.org/10.1182/blood-2016-02-700153
Published: 2016
Includes: Supplemental data
Journal Articles

Randomized study of reduced-intensity chemotherapy combined with imatinib in adults with Ph-positive acute lymphoblastic leukemia

Clinical Trials & Observations
Yves Chalandon, Xavier Thomas, Sandrine Hayette, Jean-Michel Cayuela, Claire Abbal, Françoise Huguet, Emmanuel Raffoux, Thibaut Leguay, Philippe Rousselot, Stéphane Lepretre, Martine Escoffre-Barbe, Sébastien Maury, Céline Berthon, Emmanuelle Tavernier, Jean-François Lambert, Marina Lafage-Pochitaloff, Véronique Lhéritier, Sylvie Chevret, Norbert Ifrah, Hervé Dombret
Journal: Blood
Blood (2015) 125 (24): 3711–3719.
https://doi.org/10.1182/blood-2015-02-627935
Published: 2015
Includes: Supplemental data
Journal Articles

Value of Cytogenetic Abnormalities in Adult Patients with Philadelphia Chromosome (Ph)-Negative Acute Lymphoblastic Leukemia (ALL) Treated in the Pediatric-Inspired Trials from the Group for Research on Adult ALL (GRAALL)

Marina Lafage-Pochitaloff, Laurence Baranger, Mathilde Hunault, Wendy Cuccuini, MD, Audrey Bidet, Nicole Dastugue, MD, Isabelle Tigaud, MD, Catherine Henry, Carine Gervais, MD, Dominique Penther, Christine Lefebvre, Nathalie Nadal, Francine Mugneret, Virginie Eclache, Isabelle Radford, Nathalie Gachard, Marie-Joelle Mozziconacci, Eric Delabesse, Marie C Bene, Agnès Chassevent, Kheira Beldjord, Vahid Asnafi, MDPhD, Françoise Huguet, Véronique Lhéritier, Norbert Ifrah, Hervé Dombret, MD PhD
Journal: Blood
Blood (2014) 124 (21): 492.
https://doi.org/10.1182/blood.V124.21.492.492
Published: 2014
Journal Articles

Outcome of Younger Adults with Philadelphia Chromosome (Ph)-Negative Acute Lymphoblastic Leukemia (ALL) in First Relapse: A Graall Study

Alexandre Desjonqueres, resident, Patrice Chevallier, MD PhD, Xavier Thomas, MD PhD, Françoise Huguet, MD, Thibault Leguay, MD, Marc Bernard, MD, Jacques-Olivier Bay, MD PhD, Emmanuelle Tavernier, MD, Aude Charbonnier, MD, Françoise Isnard, MD, Mathilde Hunault, Pascal Turlure, MD, Marc Renaud, MD, Jean-Noel M. Bastie, MD PhD, Chantal Himberlin, MD, Stephane Lepretre, MD, Bruno Lioure, MD PhD, Véronique Lhéritier, Vahid Asnafi, Kheira Beldjord, Marina Lafage, Norbert Ifrah, Herve Dombret, MD
Journal: Blood
Blood (2014) 124 (21): 931.
https://doi.org/10.1182/blood.V124.21.931.931
Published: 2014
Journal Articles

Value of EVI1 Gene Expression Level in Adult Acute Lymphoblastic Leukemia (ALL): A Study from the Group for Research on Adult ALL (GRAALL)

Claire Abbal, Raouf Ben Abdelali, Marina Lafage, Françoise Huguet, Thibaut Leguay, Olivier Spertini, Nicolas Boissel, Claude Gardin, Carlos Graux, Jean-Michel Cayuela, Marie-Laure Boulland, Nathalie Grardel, Anne Bouvier, Michel Duchosal, MD, Véronique Lhéritier, Yves Chalandon, Vahid Asnafi, MDPhD, Norbert Ifrah, Hervé Dombret, MD PhD
Journal: Blood
Blood (2014) 124 (21): 1081.
https://doi.org/10.1182/blood.V124.21.1081.1081
Published: 2014
Journal Articles

Oncogenetics and minimal residual disease are independent outcome predictors in adult patients with acute lymphoblastic leukemia

Clinical Trials & Observations
Kheira Beldjord, Sylvie Chevret, Vahid Asnafi, Françoise Huguet, Marie-Laure Boulland, Thibaut Leguay, Xavier Thomas, Jean-Michel Cayuela, Nathalie Grardel, Yves Chalandon, Nicolas Boissel, Beat Schaefer, Eric Delabesse, Hélène Cavé, Patrice Chevallier, Agnès Buzyn, Thierry Fest, Oumedaly Reman, Jean-Paul Vernant, Véronique Lhéritier, Marie C. Béné, Marina Lafage, Elizabeth Macintyre, Norbert Ifrah, Hervé Dombret
Journal: Blood
Blood (2014) 123 (24): 3739–3749.
https://doi.org/10.1182/blood-2014-01-547695
Published: 2014
Includes: Supplemental data
Journal Articles

NOTCH1 Mutations Are Associated With The 14q Deletion In Chronic Lymphocytic Leukemia (CLL) and Small Lymphocytic Lymphoma (SLL)

Florence Nguyen-Khac, MD, PhD, Adrien Cosson, Elise Chapiro, Nabila Belhouachi, hong-Anh Cung, Boris Keren, Frederik Damm, MD, Caroline Algrin, Christine Lefebvre, Sandra fert-Ferrer, Isabelle Luquet, MD, Nathalie Gachard, PhD, Francine Mugneret, Christine Terré, Marie-Agnes Collonge-Rame, Lucienne Michaux, MD PhD, Isabelle Radford-Weiss, Pascaline Talmant, Lauren Veronese, MD, PhD, Nathalie Nadal, Stephanie Struski, Carole Barin, Catherine Helias, Marina Lafage, Éric Lippert, MD, PhD, Nathalie Auger, M.D., Virginie Eclache, MD, Catherine Settegrana, MD, Karim Maloum, MD, PhD, CLaude Lesty, Frederic Davi, MD, PhD, Hélène Merle-Beral, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2561.
https://doi.org/10.1182/blood.V122.21.2561.2561
Published: 2013
Journal Articles

Is Less Chemotherapy Detrimental in Adults with Philadelphia Chromosome (Ph)-Positive Acute Lymphoblastic Leukemia (ALL) Treated with High-Dose Imatinib? Results of the Prospective Randomized Graaph-2005 Study

Yves Chalandon, Xavier Thomas, MD, Sandrine Hayette, Jean-Michel Cayuela, Claire Abbal, Françoise Huguet, Emmanuel Raffoux, Thibaut Leguay, Stéphane Leprêtre, MD, Martine Escoffre-Barbe, Sébastien Maury, Céline Berthon, Emmanuelle Tavernier, Jean-Francois Lambert, Marina Lafage, Véronique Lhéritier, Sylvie Chevret, Norbert Ifrah, Hervé Dombret, MD
Journal: Blood
Blood (2012) 120 (21): 138.
https://doi.org/10.1182/blood.V120.21.138.138
Published: 2012
Journal Articles

BCR/ABL Fusion Gene On Constitutional Der(14;22) Roberstsonian Translocation in a Case of Chronic Myeloid Leukemia with Masked Philadelphia Chromosome

Pablo Lopez, Daniela Infante, Isabel Moro, Victoria Elizondo, Gerardo Romanelli, Solange Simonet, M. Rosario Uriarte Escuder, PhD, Natacha Gardiol, Juan Zunino, Marina Lafage, Rossana Bonomi
Journal: Blood
Blood (2012) 120 (21): 4822.
https://doi.org/10.1182/blood.V120.21.4822.4822
Published: 2012
Journal Articles

Dasatinib (Sprycel®) and Low Intensity Chemotherapy for First-Line Treatment in Patients with De Novo Philadelphia Positive ALL Aged 55 and Over: Final Results of the EWALL-Ph-01 Study

Philippe Rousselot, MD, PhD, Marie Magdeleine Coudé, Françoise Huguet, Marina Lafage, Thibaut Leguay, Celia Salanoubat, MD, Francis Witz, MD, Magda Alexis, MD, Maud Janvier, MD, Mathilde Hunault, MD, PhD, Philippe Agape, Christian Berthou, MD, Eric Jourdan, MD, José Fernandes, MD, Laurent Sutton, Anne Banos, Oumedaly Reman, MD, Bruno Lioure, MD, Jean-Michel Cayuela, PhD, Sandrine Hayette, Nicola Gokbuget, MD, Dieter Hoelzer, MD, Andre Delannoy, MD, Carlo Gambacorti-Passerini, MD, Renato Bassan, MD, Josep-Maria Ribera, MD, PhD, Sebastian Giebel, MD, Herve Dombret, Oliver G. Ottmann, MD
Journal: Blood
Blood (2012) 120 (21): 666.
https://doi.org/10.1182/blood.V120.21.666.666
Published: 2012
Journal Articles

Wide diversity of PAX5 alterations in B-ALL: a Groupe Francophone de Cytogénétique Hématologique study

Etienne Coyaud, Stephanie Struski, Nais Prade, Julien Familiades, Ruth Eichner, Cathy Quelen, Marina Bousquet, Francine Mugneret, Pascaline Talmant, Marie-Pierre Pages, Christine Lefebvre, Dominique Penther, Eric Lippert, Nathalie Nadal, Sylvie Taviaux, Bruce Poppe, Isabelle Luquet, Laurence Baranger, Virginie Eclache, Isabelle Radford, Carole Barin, Marie-Joëlle Mozziconacci, Marina Lafage-Pochitaloff, Hélène Antoine-Poirel, Christiane Charrin, Christine Perot, Christine Terre, Pierre Brousset, Nicole Dastugue, Cyril Broccardo
Journal: Blood
Blood (2010) 115 (15): 3089–3097.
https://doi.org/10.1182/blood-2009-07-234229
Published: 2010
Includes: Supplemental data
Journal Articles

Chromosomal Abnormalities in Transformed Ph-Negative Myeloproliferative Neoplasm Are Independent of the JAK2 and the TET2 Statuses.

Florence Nguyen-Khac, MD, PhD, Lucile Couronne, Virginie Eclache, Joris Andrieux, Eric Lippert, Olivier Kosmider, Francine Mugneret, Marie-Agnes Collonge-Rame, Dominique Penther, Marina Lafage, Nathalie Gachard, Nathalie Nadal, Marie-Joelle Mozziconacci, Nicole Dastugue, Chrystele Bilhou-Nabera, Stephanie Struski, Christine Cabrol, Isabelle Radford-Weiss, Claude Lesty, Olivier A Bernard
Journal: Blood
Blood (2009) 114 (22): 2900.
https://doi.org/10.1182/blood.V114.22.2900.2900
Published: 2009
Journal Articles

Myeloid Cell Differentiation Arrest by Mir-125b-1 in Myelodysplasic Syndrome and Acute Myeloid Leukemia with the T(2;11)(p21;q23) Translocation

Marina Bousquet, Cathy Quelen, Roberto Rosati, Véronique Mansat-De Mas, Christian Bastard, Eric Lippert, Pascaline Talmant, Marina Lafage-Pochitaloff, Dominique Leroux, Carine Gervais, Franck Viguie, Jean-Luc Lai, Christine Terre, Georges Delsol, Nicole Dastugue, Cristina Mecucci, Pierre Brousset
Journal: Blood
Blood (2008) 112 (11): 4148.
https://doi.org/10.1182/blood.V112.11.4148.4148
Published: 2008
Journal Articles

First Results of the GRAAPH-2005 Study in younger Adult Patients with De Novo Philadelphia Positive Acute Lymphoblastic Leukemia

Yves Chalandon, Xavier Thomas, Sandrine Hayette, Jean-Michel Cayuela, Sr., Claire Abbal, Martine Escoffre-Barbe, MD, Sebastien Maury, Stephane Lepretre, Francis Witz, Lofti Benboubker, Jean-Valère Malfuson, Thibaut Leguay, Agnes Buzyn, Veronique Lheritier, Marie-Christine Bene, Marina Lafage, Norbert Ifrah, Herve Dombret
Journal: Blood
Blood (2008) 112 (11): 12.
https://doi.org/10.1182/blood.V112.11.12.12
Published: 2008
Journal Articles

Prognosis of Patients with AML Carrying 11Q23/MLL Reciprocal Translocations : A Retrospective Study of 191 Cases from the French AML-Intergroup

Anne Banos, Antoine Jaquet, Anne Auvrignon, Nicole Dastugue, Christine Terré, Isabelle Luquet, MD, PhD, Sylvie Castaigne, Marina lafage Pochitaloff, Thierry Leblanc, Pierre Fenaux, MD, PhD, Francoise Huguet, Francis Witz, Didier Blaise, Josy M. Reiffers, Jean Luc Harousseau, Gerard Socie, MD, Bruno Lioure, MD, Christian Bastard, Herve Dombret, MD, Arnaud Pigneux, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 2547.
https://doi.org/10.1182/blood.V112.11.2547.2547
Published: 2008
Journal Articles

PAX5 Mutations Occur Frequently in Adult B-Cell Acute Lymphoblastic Leukemia (B-ALL) and Is Significantly Associated with BCR-ABL1 Fusion Gene.

Julien Familiades, Marina Bousquet, Nicole Dastugue, Marina Lafage-Pochitaloff, Béné Marie-Christine, Kheira Beldjord, Jean-Michel Cayuela, Nathalie Grardel, Claude Preudhomme, Hélène Cavé, Véronique Lhéritier, André Delannoy, Yves Chalandon, Norbert Ifrah, Arnaud Pigneux, Hervé Dombret, Elizabeth A. Macintyre, Françoise Huguet, Pierre Brousset, Cyril Broccardo, Eric Delabesse
Journal: Blood
Blood (2007) 110 (11): 2806.
https://doi.org/10.1182/blood.V110.11.2806.2806
Published: 2007