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Journal Articles

Iron homeostasis governs erythroid phenotype in polycythemia vera

Blood (2023) 141 (26): 3199–3214.

https://doi.org/10.1182/blood.2022016779

Published: 2023

Includes: Supplemental data

Journal Articles

The histone lysine acetyltransferase HBO1 (KAT7) regulates hematopoietic stem cell quiescence and self-renewal

Yuqing Yang, Andrew J. Kueh, Zoe L. Grant, Waruni Abeysekera, Alexandra L. Garnham, Stephen Wilcox, Craig D. Hyland, Ladina Di Rago, Don Metcalf, Warren S. Alexander, Leigh Coultas, Gordon K. Smyth, Anne K. Voss, Tim Thomas

Blood (2022) 139 (6): 845–858.

https://doi.org/10.1182/blood.2021013954

Published: 2022

Includes: Supplemental data

Journal Articles

PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia

Blood (2019) 133 (16): 1729–1741.

https://doi.org/10.1182/blood-2018-07-860726

Published: 2019

Includes: Supplemental data

Journal Articles

MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML

Blood (2018) 132 (14): 1526–1534.

https://doi.org/10.1182/blood-2018-05-852566

Published: 2018

Includes: Supplemental data

Journal Articles

Feedback Regulation of STAT5 Is Critical to Balance MYC and BCL6-Dependent Transcriptional Programs That Regulate Cell Size and Glucose Metabolism

Zhengshan Chen, MD PhD, Huimin Geng, PhD, Lars Klemm, BSc, MSc, Lai N Chan, PhD, Brass Daniel, PhD, Warren S. Alexander, PhD, Cheryl L. Willman, MD, Markus Müschen, MD PhD

Blood (2016) 128 (22): 4069.

https://doi.org/10.1182/blood.V128.22.4069.4069

Published: 2016

Journal Articles

Runx1 downregulates stem cell and megakaryocytic transcription programs that support niche interactions

Kira Behrens, Ioanna Triviai, Maike Schwieger, Nilgün Tekin, Malik Alawi, Michael Spohn, Daniela Indenbirken, Marion Ziegler, Ursula Müller, Warren S. Alexander, Carol Stocking

Blood (2016) 127 (26): 3369–3381.

https://doi.org/10.1182/blood-2015-09-668129

Published: 2016

Includes: Supplemental data

Journal Articles

Regulation of Platelet Lifespan in the Presence and Absence of TPO Signaling

Marion Lebois, Mark R. Dowling, Philip D. Hodgkin, Benjamin T. Kile, Warren S. Alexander, Emma C. Josefsson

Blood (2015) 126 (23): 11.

https://doi.org/10.1182/blood.V126.23.11.11

Published: 2015

Journal Articles

Mouse prenatal platelet-forming lineages share a core transcriptional program but divergent dependence on MPL

Kathryn S. Potts, Tobias J. Sargeant, Caleb A. Dawson, Emma C. Josefsson, Douglas J. Hilton, Warren S. Alexander, Samir Taoudi

Blood (2015) 126 (6): 807–816.

https://doi.org/10.1182/blood-2014-12-616607

Published: 2015

Includes: Supplemental data

Journal Articles

Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis

Stanley C. W. Lee, Sarah Miller, Craig Hyland, Maria Kauppi, Marion Lebois, Ladina Di Rago, Donald Metcalf, Sarah A. Kinkel, Emma C. Josefsson, Marnie E. Blewitt, Ian J. Majewski, Warren S. Alexander

Blood (2015) 126 (2): 167–175.

https://doi.org/10.1182/blood-2014-12-615898

Published: 2015

Includes: Supplemental data

Journal Articles

Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2

Sarah A. Kinkel, Roman Galeev, Christoffer Flensburg, Andrew Keniry, Kelsey Breslin, Omer Gilan, Stanley Lee, Joy Liu, Kelan Chen, Linden J. Gearing, Darcy L. Moore, Warren S. Alexander, Mark Dawson, Ian J. Majewski, Alicia Oshlack, Jonas Larsson, Marnie E. Blewitt

Blood (2015) 125 (12): 1890–1900.

https://doi.org/10.1182/blood-2014-10-603969

Published: 2015

Includes: Supplemental data

Journal Articles

MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development

Bilal N. Sheikh, Stanley C. W. Lee, Farrah El-Saafin, Hannah K. Vanyai, Yifang Hu, Swee Heng Milon Pang, Stephanie Grabow, Andreas Strasser, Stephen L. Nutt, Warren S. Alexander, Gordon K. Smyth, Anne K. Voss, Tim Thomas

Blood (2015) 125 (12): 1910–1921.

https://doi.org/10.1182/blood-2014-08-594655

Published: 2015

Includes: Supplemental data

Journal Articles

A crucial role for the homeodomain transcription factor Hhex in lymphopoiesis

Jacob T. Jackson, Chayanica Nasa, Wei Shi, Nicholas D. Huntington, Clifford W. Bogue, Warren S. Alexander, Matthew P. McCormack

Blood (2015) 125 (5): 803–814.

https://doi.org/10.1182/blood-2014-06-579813

Published: 2015

Includes: Supplemental data

Journal Articles

Erk and Stat5 Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia

Shojaee Seyedmehdi, PhD, Zhengshan Chen, MD PhD, Maike Buchner, PhD, Christian Hurtz, PhD, Huimin Geng, PhD, Hilde Schjerven, PhD, Lai N Chan, PhD, Phillip Koeffler, MD, Cheryl L. Willman, MD, Stephen Hunger, MD, Sinisa Dovat, MD,PhD, Elisabeth Paietta, PhD, Wolf-Karsten Hofmann, Ari M Melnick, MD, Warren S. Alexander, Steven M. Kornblau, MD, Markus Muschen, MDPhD

Blood (2014) 124 (21): 787.

https://doi.org/10.1182/blood.V124.21.787.787

Published: 2014

Journal Articles

A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo

Kathryn S. Potts, Tobias J. Sargeant, John F. Markham, Wei Shi, Christine Biben, Emma C. Josefsson, Lachlan W. Whitehead, Kelly L. Rogers, Anna Liakhovitskaia, Gordon K. Smyth, Benjamin T. Kile, Alexander Medvinsky, Warren S. Alexander, Douglas J. Hilton, Samir Taoudi

Blood (2014) 124 (17): 2725–2729.

https://doi.org/10.1182/blood-2014-02-559468

Published: 2014

Includes: Supplemental data

Journal Articles

Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes

Diwakar R. Pattabiraman, Crystal McGirr, Konstantin Shakhbazov, Valerie Barbier, Keerthana Krishnan, Pamela Mukhopadhyay, Paula Hawthorne, Ann Trezise, Jianmin Ding, Sean M. Grimmond, Peter Papathanasiou, Warren S. Alexander, Andrew C. Perkins, Jean-Pierre Levesque, Ingrid G. Winkler, Thomas J. Gonda

Blood (2014) 123 (17): 2682–2690.

https://doi.org/10.1182/blood-2012-02-413187

Published: 2014

Includes: Supplemental data

Journal Articles

cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner

W. Wei-Lynn Wong, James E. Vince, Najoua Lalaoui, Kate E. Lawlor, Diep Chau, Aleksandra Bankovacki, Holly Anderton, Donald Metcalf, Lorraine O’Reilly, Philipp J. Jost, James M. Murphy, Warren S. Alexander, Andreas Strasser, David L. Vaux, John Silke

Blood (2014) 123 (16): 2562–2572.

https://doi.org/10.1182/blood-2013-06-510743

Published: 2014

Includes: Supplemental data

Journal Articles

Polycomb repressive complex 2 (PRC2) suppresses Eμ- myc lymphoma

Stanley C. W. Lee, Belinda Phipson, Craig D. Hyland, Huei San Leong, Rhys S. Allan, Aaron Lun, Douglas J. Hilton, Stephen L. Nutt, Marnie E. Blewitt, Gordon K. Smyth, Warren S. Alexander, Ian J. Majewski

Blood (2013) 122 (15): 2654–2663.

https://doi.org/10.1182/blood-2013-02-484055

Published: 2013

Includes: Supplemental data

Journal Articles

Interaction of c-Myb with p300 Is Required for the Induction of Acute Myeloid Leukemia by Human AML Oncogenes, and Represents a Potential Therapeutic Target.

Diwakar R Pattabiraman, PhD, Konstantin Shakhbazov, PhD, Valerie Barbier, Crystal McGirr, BSc (Hons), Keerthana Krishnan, BSc (Hons), Pamela Mukhopadhyay, PhD, Paula Hawthorne, PhD, Ann Trezise, PhD, Sean Grimmond, PhD, Peter Papathanasiou, Andrew C. Perkins, MBBS, PhD, FRACP, FRCPA, Jean-Pierre Levesque, PhD, Warren S. Alexander, Ingrid G Winkler, PhD, Thomas J Gonda, PhD

Blood (2012) 120 (21): 2402.

https://doi.org/10.1182/blood.V120.21.2402.2402

Published: 2012

Journal Articles

Suppressor of Cytokine Signaling (SOCS) Molecules Are Critical to Balance Oncogenic Signaling Strength in Ph + ALL.

Zhengshan Chen, MD, PhD, Huimin Geng, PhD, Lars Klemm, Maike Buchner, PhD, Kaveh Hemati, BS, Seyedmehdi Shojaee, M.Sc., Warren S. Alexander, William L. Carroll, MD, Cheryl L Willman, MD, Markus Muschen, MD

Blood (2012) 120 (21): 2563.

https://doi.org/10.1182/blood.V120.21.2563.2563

Published: 2012

Journal Articles

Hematopoietic Overexpression of the ETS Family Transcription Factor Erg, or the Oncogenic Fusion Protein TLS-ERG, Induces Erythro-Megakaryocytic Leukemia

Catherine L Carmichael, PhD, Donald Metcalf, Katya J. Henley, Elizabeth A Kruse, PhD, Ladina Di Rago, Sandra Mifsud, Jian Zhong Tang, PhD, Warren S. Alexander, Benjamin T. Kile

Blood (2012) 120 (21): 1283.

https://doi.org/10.1182/blood.V120.21.1283.1283

Published: 2012

NARROW

Iron homeostasis governs erythroid phenotype in polycythemia vera

The histone lysine acetyltransferase HBO1 (KAT7) regulates hematopoietic stem cell quiescence and self-renewal

PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia

MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML

Feedback Regulation of STAT5 Is Critical to Balance MYC and BCL6-Dependent Transcriptional Programs That Regulate Cell Size and Glucose Metabolism

Runx1 downregulates stem cell and megakaryocytic transcription programs that support niche interactions

Regulation of Platelet Lifespan in the Presence and Absence of TPO Signaling

Mouse prenatal platelet-forming lineages share a core transcriptional program but divergent dependence on MPL

Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis

Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2

MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development

A crucial role for the homeodomain transcription factor Hhex in lymphopoiesis

Erk and Stat5 Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia

A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo

Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes

cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner

Polycomb repressive complex 2 (PRC2) suppresses Eμ- myc lymphoma

Interaction of c-Myb with p300 Is Required for the Induction of Acute Myeloid Leukemia by Human AML Oncogenes, and Represents a Potential Therapeutic Target.

Suppressor of Cytokine Signaling (SOCS) Molecules Are Critical to Balance Oncogenic Signaling Strength in Ph + ALL.

Hematopoietic Overexpression of the ETS Family Transcription Factor Erg, or the Oncogenic Fusion Protein TLS-ERG, Induces Erythro-Megakaryocytic Leukemia

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American Society of Hematology

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American Society of Hematology

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