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Journal Articles

Mechanistic approach exploring combination agents to potentiate anti-leukemia activity of Hu8F4, a clinical stage T cell receptor mimic antibody

Anna Sergeeva, Hong He, Lisa St. John, Ling Yu, Rong Cai, Rolando Vedia, Celine Kerros, Kathryn Cox, Karen Clise-Dwyer, Gheath Alatrash, Jeffrey Molldrem

Blood (2025) 146 (Supplement 1): 1513.

https://doi.org/10.1182/blood-2025-1513

Published: 2025

Journal Articles

Development of a novel LRP1 antibody that identifies upregulation of membrane LRP1 on activated and chimeric antigen receptor T cells

Rolando Vedia, Dan Li, Lisa St. John, Sijie Lu, Tian-Hui Yang, Qing Ma, Jeffrey Molldrem

Blood (2025) 146 (Supplement 1): 7637.

https://doi.org/10.1182/blood-2025-7637

Published: 2025

Journal Articles

LRP-1 regulates T cell proliferation and activation through global lipid network and loss of LRP-1 eliminates GVHD In Vivo

Dan Li, Iqbal Mahmud, Shengqing Gu, Lisa St. John, Qing Ma, Jeffrey Molldrem

Blood (2025) 146 (Supplement 1): 2306.

https://doi.org/10.1182/blood-2025-2306

Published: 2025

Journal Articles

P-selectin blockade effectively prevents trauma-induced microvascular obstruction

Reheman Adili, Maria Ronquillo, Nicole Roads, Hallie Lazaro, Jennifer Doan, Richard Maldonado, Junmei Chen, Dominic Chung, José López, Alexander St. John

Blood (2025) 146 (Supplement 1): 1320.

https://doi.org/10.1182/blood-2025-1320

Published: 2025

Journal Articles

A phase I study of the T-cell receptor-like antibody Hu8F4 in pts with advanced myeloid neoplasms

Blood (2025) 146 (Supplement 1): 1646.

https://doi.org/10.1182/blood-2025-1646

Published: 2025

Journal Articles

Critical Bleeding in Adults and Children with Immune Thrombocytopenia: A Multicentre Cohort Study

Blood (2024) 144 (Supplement 1): 547.

https://doi.org/10.1182/blood-2024-210851

Published: 2024

Journal Articles

A Phase I Study of Nivolumab in Combination with Ipilimumab for the Treatment of Patients with High Risk or Refractory/Relapsed Acute Myeloid Leukemia Following Allogeneic Stem Cell Transplantation

Blood (2024) 144 (Supplement 1): 1047.

https://doi.org/10.1182/blood-2024-211343

Published: 2024

Journal Articles

Cord-Derived Invariant Natural Killer T Cells As Novel Cell Therapy to Improve the Outcome of Hematopoietic Stem Cell Transplantation

Abel Trujillo-Ocampo, Maison Grefe, Pamella Borges, Jelita Clinton, Hong He, Dan Li, Ling Yu, Martiela Vaz de Freitas, Lisa St. John, Karen Clise-Dwyer, Gheath Alatrash, Dinler Amaral Antues, Qing Ma, Jeffrey J. Molldrem, Elizabeth J. Shpall, Jin S. Im

Blood (2024) 144 (Supplement 1): 4818.

https://doi.org/10.1182/blood-2024-210168

Published: 2024

Journal Articles

Clinical and Serological Characteristics of Vaccine-Associated Immune Thrombocytopenia Following COVID-19 Vaccination

Reid C. Gallant, Melanie St John, Yang Liu, Madison Cranstone, John G. Kelton, Ishac Nazy, Donald Arnold

Blood (2024) 144 (Supplement 1): 1243.

https://doi.org/10.1182/blood-2024-194652

Published: 2024

Journal Articles

Phase I Study of the T-Cell Receptor-like Antibody, Hu8F4 in Patients with Relapsed and Refractory Myeloid Malignancies

Blood (2023) 142 (Supplement 1): 1545.

https://doi.org/10.1182/blood-2023-189966

Published: 2023

Journal Articles

Evaluation of Bleeding Self-Assessments By Patients with Immune Thrombocytopenia (ITP): An Agreement Study

Bianca Clerici, Ngan Tang, Madison Cranstone, Yang Liu, Milena Hadzi-Tosev, Joanne Nixon, Melanie St John, Maryam Shirinzadeh, Erin Jamula, John G. Kelton, Donald Arnold

Blood (2023) 142 (Supplement 1): 3958.

https://doi.org/10.1182/blood-2023-187067

Published: 2023

Journal Articles

CD47 Blockade Enhances Phagocytic Activity of the TCR-Mimic Antibody Hu8F4 Against HLA-A2+ AML

Anna Sergeeva, Hong He, Lisa St. John, Ling Yu, Rong Cai, Kathryn Ruissard, Karen Clise-Dwyer, Rolando Vedia, Dan Li, Qing Ma, Celine Kerros, Mithil Chokshi, Vanshika Jhonsa, Gang Bao, Gheath Alatrash, Jeffrey J. Molldrem

Blood (2023) 142 (Supplement 1): 4176.

https://doi.org/10.1182/blood-2023-190099

Published: 2023

Journal Articles

AML Immunotherapy Using a Novel Tcrm-Based Bispecific Antibody That Targets a Leader Sequence Peptide Derived from Cathepsin G

Chunhua Shi, Ze Tian, Jun Yan, Mao Zhang, Pariya Sukhumalchandra, Edward Chang, Guojun Yang, Junping You, Meng Cui, Qing Shi, Anne Philips, Na Qiao, Anna Sergeeva, Lisa St. John, Hong He, Dongxing Zha, Jeffrey J. Molldrem, Gheath Alatrash

Blood (2023) 142 (Supplement 1): 1415.

https://doi.org/10.1182/blood-2023-189514

Published: 2023

Journal Articles

Low-density lipoprotein promotes microvascular thrombosis by enhancing von Willebrand factor self-association

Dominic W. Chung, Kimsey Platten, Koya Ozawa, Reheman Adili, Nathalie Pamir, Forrest Nussdorfer, Alexander St. John, Minhua Ling, Jennie Le, Jeff Harris, Nicole Rhoads, Yi Wang, Xiaoyun Fu, Junmei Chen, Sergio Fazio, Jonathan R. Lindner, José A. López

Blood (2023) 142 (13): 1156–1166.

https://doi.org/10.1182/blood.2023019749

Published: 2023

Includes: Multimedia, Supplemental data

Journal Articles

A novel melanocortin fusion protein inhibits fibrinogen oxidation and degradation during trauma-induced coagulopathy

Chang Yeop Han, Xu Wang, Kristyn M. Ringgold, Jennifer C. Bennett, Alexander E. St. John, Ronald Berenson, Susan A. Stern, Nathan J. White

Blood (2023) 142 (8): 724–741.

https://doi.org/10.1182/blood.2022019164

Published: 2023

Includes: Supplemental data

Journal Articles

Humanized T Cell Receptor-like Antibody Hu8F4 Reduces Leukemia By Fc-Mediated Mechanism

Blood (2022) 140 (Supplement 1): 9061–9062.

https://doi.org/10.1182/blood-2022-162593

Published: 2022

Journal Articles

Targeting Myeloid Leukemia Using Novel TCR-like Chimeric Antigen Receptor-T Cells Against Cathepsin G

Jun Yan, Ze Tian, Chunhua Shi, Mao Zhang, Pariya Sukhumalchandra, Guojan Yang, Qing Edward Chang, Junping You, Meng Cui, Qing Shi, Anne Philip, Na Qiao, Anna Sergeeva, Lisa St John, Hong He, Dongxing Zha, Jeffrey J. Molldrem, Gheath Alatrash

Blood (2022) 140 (Supplement 1): 7392–7393.

https://doi.org/10.1182/blood-2022-166488

Published: 2022

Journal Articles

A Novel Approach to Reduce Toxicity and Preserve Efficacy of Chimeric Antigen Receptor T Cells for Adoptive Transfer

Rolando A. Vedia, Sijie Lu, Anne Philip, Anna Sergeeva, Lisa St John, Karen Clise-Dwyer, Jeffrey J. Molldrem

Blood (2022) 140 (Supplement 1): 10269–10270.

https://doi.org/10.1182/blood-2022-158603

Published: 2022

Journal Articles

LRP1-Deficient T Cells Protect Against Acute Graft Versus Host Disease in MHC-Mismatched Mice

Olga Sizova, Dan Li, Qing Ma, Lisa St John, Karen Clise-Dwyer, Abel Trujillo-Ocampo, Jeffrey J. Molldrem

Blood (2022) 140 (Supplement 1): 4483–4484.

https://doi.org/10.1182/blood-2022-167517

Published: 2022

Journal Articles

Elevated Levels of Low Density Lipoprotein (LDL) Trigger VWF Self-Association into Fibers and Bundles and Potentiate Microvascular Thrombosis

Dominic W. Chung, Kimsey Platten, Koya Ozawa, Raymond Adili, Nathalie Pamir, Forrest D Nussdorfer, Alexander E St. John, Minhua Ling, Jennie Le, Jeff Harris, Junmei Chen, Sergio Fazio, Jonathan Lindner, José A. López

Blood (2022) 140 (Supplement 1): 1660–1661.

https://doi.org/10.1182/blood-2022-170092

Published: 2022

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Mechanistic approach exploring combination agents to potentiate anti-leukemia activity of Hu8F4, a clinical stage T cell receptor mimic antibody

Development of a novel LRP1 antibody that identifies upregulation of membrane LRP1 on activated and chimeric antigen receptor T cells

LRP-1 regulates T cell proliferation and activation through global lipid network and loss of LRP-1 eliminates GVHD In Vivo

P-selectin blockade effectively prevents trauma-induced microvascular obstruction

A phase I study of the T-cell receptor-like antibody Hu8F4 in pts with advanced myeloid neoplasms

Critical Bleeding in Adults and Children with Immune Thrombocytopenia: A Multicentre Cohort Study

A Phase I Study of Nivolumab in Combination with Ipilimumab for the Treatment of Patients with High Risk or Refractory/Relapsed Acute Myeloid Leukemia Following Allogeneic Stem Cell Transplantation

Cord-Derived Invariant Natural Killer T Cells As Novel Cell Therapy to Improve the Outcome of Hematopoietic Stem Cell Transplantation

Clinical and Serological Characteristics of Vaccine-Associated Immune Thrombocytopenia Following COVID-19 Vaccination

Phase I Study of the T-Cell Receptor-like Antibody, Hu8F4 in Patients with Relapsed and Refractory Myeloid Malignancies

Evaluation of Bleeding Self-Assessments By Patients with Immune Thrombocytopenia (ITP): An Agreement Study

CD47 Blockade Enhances Phagocytic Activity of the TCR-Mimic Antibody Hu8F4 Against HLA-A2+ AML

AML Immunotherapy Using a Novel Tcrm-Based Bispecific Antibody That Targets a Leader Sequence Peptide Derived from Cathepsin G

Low-density lipoprotein promotes microvascular thrombosis by enhancing von Willebrand factor self-association

A novel melanocortin fusion protein inhibits fibrinogen oxidation and degradation during trauma-induced coagulopathy

Humanized T Cell Receptor-like Antibody Hu8F4 Reduces Leukemia By Fc-Mediated Mechanism

Targeting Myeloid Leukemia Using Novel TCR-like Chimeric Antigen Receptor-T Cells Against Cathepsin G

A Novel Approach to Reduce Toxicity and Preserve Efficacy of Chimeric Antigen Receptor T Cells for Adoptive Transfer

LRP1-Deficient T Cells Protect Against Acute Graft Versus Host Disease in MHC-Mismatched Mice

Elevated Levels of Low Density Lipoprotein (LDL) Trigger VWF Self-Association into Fibers and Bundles and Potentiate Microvascular Thrombosis

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American Society of Hematology

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