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Pediatric Evans syndrome is associated with a high frequency of potentially damaging variants in immune genes
PD-1 blockade with pembrolizumab for classical Hodgkin lymphoma after autologous stem cell transplantation
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Table of Contents
BLOOD COMMENTARIES
CLINICAL TRIALS AND OBSERVATIONS
Pediatric Evans syndrome is associated with a high frequency of potentially damaging variants in immune genes
Clinical Trials & Observations
Jérôme Hadjadj,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Nathalie Aladjidi,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Helder Fernandes,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Guy Leverger,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Aude Magérus-Chatinet,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Fabienne Mazerolles,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Marie-Claude Stolzenberg,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Sidonie Jacques,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Capucine Picard,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Jérémie Rosain,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Cécile Fourrage,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Sylvain Hanein,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Mohammed Zarhrate,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Marlène Pasquet,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Wadih Abou Chahla,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Vincent Barlogis,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Yves Bertrand,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Isabelle Pellier,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Elodie Colomb Bottollier,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Fanny Fouyssac,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Pascale Blouin,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Caroline Thomas,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Nathalie Cheikh,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Eric Dore,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Corinne Pondarre,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Dominique Plantaz,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Eric Jeziorski,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Frédéric Millot,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Nicolas Garcelon,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Stéphane Ducassou,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Yves Perel,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Thierry Leblanc,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Bénédicte Neven,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Alain Fischer,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE),Frédéric Rieux-Laucat,on behalf of members of the French Reference Center for Pediatric Autoimmune Cytopenia (CEREVANCE)
PD-1 blockade with pembrolizumab for classical Hodgkin lymphoma after autologous stem cell transplantation
Clinical Trials & Observations
Philippe Armand,Yi-Bin Chen,Robert A. Redd,Robin M. Joyce,Jad Bsat,Erin Jeter,Reid W. Merryman,Kimberly C. Coleman,Parastoo B. Dahi,Yago Nieto,Ann S. LaCasce,David C. Fisher,Samuel Y. Ng,Oreofe O. Odejide,Arnold S. Freedman,Austin I. Kim,Jennifer L. Crombie,Caron A. Jacobson,Eric D. Jacobsen,Jeffrey L. Wong,Sanjay S. Patel,Jerome Ritz,Scott J. Rodig,Margaret A. Shipp,Alex F. Herrera
LYMPHOID NEOPLASIA
A niche-dependent myeloid transcriptome signature defines dormant myeloma cells
Weng Hua Khoo,Guy Ledergor,Assaf Weiner,Daniel L. Roden,Rachael L. Terry,Michelle M. McDonald,Ryan C. Chai,Kim De Veirman,Katie L. Owen,Khatora S. Opperman,Kate Vandyke,Justine R. Clark,Anja Seckinger,Natasa Kovacic,Akira Nguyen,Sindhu T. Mohanty,Jessica A. Pettitt,Ya Xiao,Alexander P. Corr,Christine Seeliger,Mark Novotny,Roger S. Lasken,Tuan V. Nguyen,Babatunde O. Oyajobi,Dana Aftab,Alexander Swarbrick,Belinda Parker,Duncan R. Hewett,Dirk Hose,Karin Vanderkerken,Andrew C. W. Zannettino,Ido Amit,Tri Giang Phan,Peter I. Croucher
There is a Blood Commentary on this article in this issue.
Chronic lymphocytic leukemia cells impair mitochondrial fitness in CD8+ T cells and impede CAR T-cell efficacy
Jaco A. C. van Bruggen,Anne W. J. Martens,Joseph A. Fraietta,Tom Hofland,Sanne H. Tonino,Eric Eldering,Mark-David Levin,Peter J. Siska,Sanne Endstra,Jeffrey C. Rathmell,Carl H. June,David L. Porter,J. Joseph Melenhorst,Arnon P. Kater,Gerritje J. W. van der Windt
MYELOID NEOPLASIA
RUNX1-targeted therapy for AML expressing somatic or germline mutation in RUNX1
Christopher P. Mill,Warren Fiskus,Courtney D. DiNardo,Yimin Qian,Kanak Raina,Kimal Rajapakshe,Dimuthu Perera,Cristian Coarfa,Tapan M. Kadia,Joseph D. Khoury,Dyana T. Saenz,David N. Saenz,Anuradha Illendula,Koichi Takahashi,Steven M. Kornblau,Michael R. Green,Andrew P. Futreal,John H. Bushweller,Craig M. Crews,Kapil N. Bhalla
TRANSFUSION MEDICINE
Osteopontin mediates murine transfusion-related acute lung injury via stimulation of pulmonary neutrophil accumulation
There is a Blood Commentary on this article in this issue.
LETTERS TO BLOOD
BLOOD WORK
ERRATA
RETRACTIONS
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Cover Image
Cover Image
Multiplex immunofluorescence of a biopsy specimen from a patient with relapse of Hodgkin lymphoma after autologous stem cell transplantation and pembrolizumab consolidation. Neoplastic cells (dim magenta) are embedded in an environment rich in PD-1 (yellow) positive and negative T cells (white). See the article by Armand et al on page 22.
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