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Eng-Juh Yeoh
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Journal Articles

Survival Outcomes, Efficacy and Tolerability of a Pediatric-Inspired Regimen (MASPORE) for Philadelphia-Negative Acute Lymphoblastic Leukemia in Young Adults at a Tertiary Hospital in Singapore

Victor Ling Wei Teik, Sai Lon Wann, Jing Yuan Tan, Jameelah Sheik Mohamed, Wei Ying Jen, Pak Ling Lui, Michelle Poon, Esther Hian Li Chan, Liang Piu Koh, Lip Kun Tan, Chin Hin Ng, Allen Eng Juh Yeoh, Melissa Ooi
Journal: Blood
Blood (2023) 142 (Supplement 1): 5881.
https://doi.org/10.1182/blood-2023-189139
Published: 2023
Journal Articles

The Impact of Age and Genomics on Drug Sensitivity in 1,076 Children and Adults with B-Cell Acute Lymphoblastic Leukemia

Satoshi Yoshimura, Zhenhua Li, Yoshihiro Gocho, Wenjian Yang, Kristine R Crews, Shawn H.R. Lee, Kathryn G. Roberts, Charles G. Mullighan, Mary V. Relling, Federico Antillon-Klussmann, Allen Eng Juh Yeoh, Mignon L. Loh, Mark R. Litzow, Sima Jeha, Seth E. Karol, Hiroto Inaba, Ching-Hon Pui, Marina Y. Konopleva, Nitin Jain, Wendy Stock, Elisabeth Paietta, Elias Jabbour, Steven M. Kornblau, William E. Evans, Jun J. Yang
Journal: Blood
Blood (2023) 142 (Supplement 1): 596.
https://doi.org/10.1182/blood-2023-181788
Published: 2023
Journal Articles

Mitochondrial Functional Profiling Links Apoptotic Sensitivity to Treatment Outcomes Based on Age and Cell Lineage in Acute Leukemia

Prasad Ramanakrishnan Iyer, Shaista Shabbir Jasdanwala, Jameelah Binte Sekh Mohamed, Si Ting Tai, Wei-Ying Jen, Melissa Ooi, Allen Eng Juh Yeoh, Shruti Bhatt
Journal: Blood
Blood (2023) 142 (Supplement 1): 5966.
https://doi.org/10.1182/blood-2023-188541
Published: 2023
Journal Articles

Roles of the SWI/SNF Chromatin Remodelling Factors in Sustaining Oncogenic Transcription Program in T-Cell Acute Lymphoblastic Leukaemia

Hyoju Kim, Tze King Tan, Xiao Zi Huang, Jolynn Ong, Rui Yokomori, Allen Eng Juh Yeoh, Takaomi Sanda, Shi Hao Tan
Journal: Blood
Blood (2022) 140 (Supplement 1): 5896–5897.
https://doi.org/10.1182/blood-2022-162528
Published: 2022
Journal Articles

Enhanced BNT162b2 vaccine-induced cellular immunity in anti-CD19 CAR T cell–treated patients

Clinical Trials & Observations
Bernice Ling Zhi Oh, Nicole Tan, Ruklanthi de Alwis, Kamini Kunasegaran, Zhiwei Chen, Michelle Poon, Esther Chan, Jenny G. H. Low, Allen Eng Juh Yeoh, Antonio Bertoletti, Nina Le Bert
Journal: Blood
Blood (2022) 140 (2): 156–160.
https://doi.org/10.1182/blood.2022016166
Published: 2022
Includes: Supplemental data
Journal Articles

The Impact of Genetic Ancestry on the Biology and Prognosis of Childhood Acute Lymphoblastic Leukemia

Shawn Lee, Federico Antillón, Deqing Pei, Wenjian Yang, Kathryn G Roberts, Zhenhua Li, Meenakshi Devidas, Wentao Yang, Cesar Najera, Hai Peng Lin, Ah Moy Tan, Hany Ariffin, Cheng Cheng, William E. Evans, Stephen P Hunger, Sima Jeha, Charles G. Mullighan, Mignon L. Loh, Allen Eng Juh Yeoh, Ching-Hon Pui, Jun J. Yang
Journal: Blood
Blood (2021) 138 (Supplement 1): 3476.
https://doi.org/10.1182/blood-2021-145655
Published: 2021
Journal Articles

Clinical Outcomes of Adults and Young Adults (AYA) with Acute Lymphoblastic Leukemia (ALL): A Multicenter Analysis of Pediatric-Inspired Protocol (MASPORE) Vs Hyper-CVAD in Singapore

Sai Lon Wann, Tertius Tuy, Victor Ling Wei Teik, Christian Gallardo, Lip Leong Chong, Samuel Sherng Young Wang, Nurul Aidah Abdul Halim, Yar Myint Zay, Allen Eng Juh Yeoh, Sampath Venkata Sreekanth, Chin Hin Ng, Michelle Poon, Gee Chuan Wong, Melissa Ooi
Journal: Blood
Blood (2021) 138 (Supplement 1): 1238.
https://doi.org/10.1182/blood-2021-150615
Published: 2021
Journal Articles

Molecular basis of ETV6 -mediated predisposition to childhood acute lymphoblastic leukemia

Rina Nishii, Rebekah Baskin-Doerfler, Wentao Yang, Ninad Oak, Xujie Zhao, Wenjian Yang, Keito Hoshitsuki, Mackenzie Bloom, Katherine Verbist, Melissa Burns, Zhenhua Li, Ting-Nien Lin, Maoxiang Qian, Takaya Moriyama, Julie M. Gastier-Foster, Karen R. Rabin, Elizabeth Raetz, Charles Mullighan, Ching-Hon Pui, Allen Eng-Juh Yeoh, Jinghui Zhang, Monika L. Metzger, Jeffery M. Klco, Stephen P. Hunger, Scott Newman, Gang Wu, Mignon L. Loh, Kim E. Nichols, Jun J. Yang
Journal: Blood
Blood (2021) 137 (3): 364–373.
https://doi.org/10.1182/blood.2020006164
Published: 2021
Includes: Supplemental data
Journal Articles

RNA Sequencing in Childhood B-Lymphoblastic Leukemia Improves Molecular and Risk Assignment

Allen Eng Juh Yeoh, MD, Zhenhua Li, PhD, Shawn Lee, MD, Winnie Hui Ni Chin, Nan Jiang, PhD, Yi Lu, PhD, Shirley Kow Yin Kham, BSc, Ah Moy Tan, MD, Hai_peng Lin, Thuan Chong Quah, Hany Ariffin, Jun J. Yang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 651.
https://doi.org/10.1182/blood-2019-131653
Published: 2019
Journal Articles

Acute Lymphoblastic Leukemia with Zinc-Finger Protein 384 (ZNF384)-Related Rearrangements: A Retrospective Analysis from the Ponte Di Legno Childhood ALL Working Group

Shinsuke Hirabayashi, Ellie Butler, Kentaro Ohki, MD PhD, Nobutaka Kiyokawa, MD PhD, Anke K. Bergmann, Judith M. Boer, PhD, Hélène Cavé, PharmD, PhD, Giovanni Cazzaniga, Allen Eng Juh Yeoh, Toshihiko Imamura, MD PhD, Hiroto Inaba, MD, Mignon L. Loh, MD, Ulrika Norén-Nyström, MD PhD, Agata Pastorczak, Lee-Yung Shih, MD, Marketa Zaliova, MD PhD, Oskar A Haas, Christine J. Harrison, PhD FRCPath, Anthony V. Moorman, Atsushi Manabe, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 652.
https://doi.org/10.1182/blood-2019-123236
Published: 2019
Journal Articles

Identification of New Risk Loci and Regulatory Mechanisms Influencing Genetic Susceptibility to Acute Lymphoblastic Leukaemia

Jayaram Vijayakrishnan, Maoxiang Qian, James B Studd, Wenjian Yang, Ben Kinnersley, Philip Law, Peter Broderick, Elizabeth A. Raetz, MD, James M. Allan, Ching-Hon Pui, MD, Ajay Vora, William E. Evans, PharmD, Anthony V. Moorman, Allen Eng Juh Yeoh, Chunliang Li, Claus Bartram, Charles G. Mullighan, MBBS, MD, Martin Zimmermann, Stephen P. Hunger, MD, Martin Schrappe, MD PhD, Mary V. Relling, PharmD, Martin Stanulla, Mignon L. Loh, MD, Richard S. Houlston, Jun J. Yang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 650.
https://doi.org/10.1182/blood-2019-125791
Published: 2019
Journal Articles

Successful Toxicity Reduction in Ma-Spore ALL 2010 in Standard/Intermediate Risk Childhood ALL: Replacing Cytarabine/Doxorubicin with More Vincristine and L-Asparaginase during Consolidation and Delayed Intensification

Bernice Oh, MBBS, MRCP, Shawn Lee, MD, Zelia Seeto, Germaine Liew, Bsc, Edwynn Chiew, MBBS, Zhi Wei Chen, Bsc, Yiong Huak Chan, PhD, Jing Jia Eng, Bsc, Koon Mian Foo, Bsc, Ching Mei Joyce Lam, MD, Ah Moy Tan, MD, Allen Eng Juh Yeoh, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1307.
https://doi.org/10.1182/blood-2019-122098
Published: 2019
Journal Articles

RNA-Seq Can Help Identify IGH Disease Clones for MRD Monitoring in Childhood B-Lymphoblastic Leukemia

Zhenhua Li, PhD, Nan Jiang, PhD, Evelyn Huizi Lim, Winnie Hui Ni Chin, Shirley Kow Yin Kham, BSc, Wentao Yang, Thuan Chong Quah, Hai_peng Lin, Ah Moy Tan, MD, Hany Ariffin, Jun J. Yang, PhD, Allen Eng Juh Yeoh, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1471.
https://doi.org/10.1182/blood-2019-131548
Published: 2019
Journal Articles

The enhancer RNA ARIEL activates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia

Shi Hao Tan, Wei Zhong Leong, Phuong Cao Thi Ngoc, Tze King Tan, Fatima Carla Bertulfo, Mei Chee Lim, Omer An, Zhenhua Li, Allen Eng Juh Yeoh, Melissa J. Fullwood, Daniel G. Tenen, Takaomi Sanda
Journal: Blood
Blood (2019) 134 (3): 239–251.
https://doi.org/10.1182/blood.2018874503
Published: 2019
Includes: Supplemental data
Journal Articles

Tolerable Dose of 6-Mercaptopurine and Prognostic Impact of NUDT15-Deficient Genotype in Childhood Acute Lymphoblastic Leukemia

Yoichi Tanaka, PhD, Motohiro Kato, MD PhD, Takaya Moriyama, MD PhD, Yuki Arakawa, MD, Daisuke Hasegawa, MD PhD, Junya Fujimura, MD PhD, Dai Keino, MD PhD, Atsushi Sato, MD, Takahiro Ueda, MD PhD, Yuichi Taneyama, MD, Masatoshi Takagi, MD PhD, Masaki Yamamoto, MD, Masaki Matsuoka, MD, Moeko Hino, MD, Hiroki Hori, MD PhD, Katsuyoshi Koh, MD, Allen Eng Juh Yeoh, MD, Jun J. Yang, PhD, Atsushi Manabe, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4032.
https://doi.org/10.1182/blood-2018-99-114290
Published: 2018
Journal Articles

Preclinical evaluation of NUDT15 -guided thiopurine therapy and its effects on toxicity and antileukemic efficacy

Rina Nishii, Takaya Moriyama, Laura J. Janke, Wenjian Yang, Chase C. Suiter, Ting-Nien Lin, Lie Li, Kentaro Kihira, Hidemi Toyoda, Ute Hofmann, Matthias Schwab, Masatoshi Takagi, Tomohiro Morio, Atsushi Manabe, Shirley Kham, Nan Jiang, Karen R. Rabin, Motohiro Kato, Katsuyoshi Koh, Allen Eng-Juh Yeoh, Hiroki Hori, Jun J. Yang
Journal: Blood
Blood (2018) 131 (22): 2466–2474.
https://doi.org/10.1182/blood-2017-11-815506
Published: 2018
Includes: Supplemental data
Journal Articles

Intensifying Treatment in Childhood B-Lymphoblastic Leukemia with IKZF1 Deletions Negates Its Adverse Outcome: Results of Ma-Spore ALL 2003 and 2010 Studies

Yi Lu, PhD, Winnie Hui Ni Chin, Evelyn Huizi Lim, Shirley Kow Yin Kham, BSc, Ah Moy Tan, MD, Hany Ariffin, MD PhD, Allen Eng Juh Yeoh, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 478.
https://doi.org/10.1182/blood.V130.Suppl_1.478.478
Published: 2017
Journal Articles

Pediatric-Inspired Protocol Improved Overall Survival in Young Adult Aged 18-30 Years Old with Philadelphia-Negative Acute Lymphoblastic Leukemia Compared to the Standard Adult Hypercvad Protocol

Victor Ling Wei Teik, MD MRCP, Elaine Seah, BSc, Michelle Poon, Melissa Ooi, Allen Eng Juh Yeoh, MD, Chin Hin Ng, MD MRCP
Journal: Blood
Blood (2017) 130 (Supplement 1): 5043.
https://doi.org/10.1182/blood.V130.Suppl_1.5043.5043
Published: 2017
Journal Articles

Novel variants in NUDT15 and thiopurine intolerance in children with acute lymphoblastic leukemia from diverse ancestry

Clinical Trials & Observations Brief Report
Takaya Moriyama, Yung-Li Yang, Rina Nishii, Hany Ariffin, Chengcheng Liu, Ting-Nien Lin, Wenjian Yang, Dong-Tsamn Lin, Chih-Hsiang Yu, Shirley Kham, Ching-Hon Pui, William E. Evans, Sima Jeha, Mary V. Relling, Allen Eng-Juh Yeoh, Jun J. Yang
Journal: Blood
Blood (2017) 130 (10): 1209–1212.
https://doi.org/10.1182/blood-2017-05-782383
Published: 2017
Includes: Supplemental data
Journal Articles

Whole-genome noncoding sequence analysis in T-cell acute lymphoblastic leukemia identifies oncogene enhancer mutations

Shaoyan Hu, Maoxiang Qian, Hui Zhang, Yu Guo, Jin Yang, Xujie Zhao, Hailong He, Jun Lu, Jian Pan, Meimei Chang, Guoqing Du, Ting-Nien Lin, Shirley Kow-Yin Kham, Thuan Chong Quah, Hany Ariffin, Ah-Moy Tan, Yong Cheng, Chunliang Li, Allen Eng-Juh Yeoh, Ching-Hon Pui, Anders Jacobsen Skanderup, Jun J. Yang
Journal: Blood
Blood (2017) 129 (24): 3264–3268.
https://doi.org/10.1182/blood-2017-03-771162
Published: 2017
Includes: Supplemental data