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Ibrutinib efficacy and tolerability in patients with relapsed chronic lymphocytic leukemia following allogeneic HCT
High-level ROR1 associates with accelerated disease progression in chronic lymphocytic leukemia
Serum free light chains, not urine specimens, should be used to evaluate response in light-chain multiple myeloma
Issue Archive
December 22 2016
Table of Contents
BLOOD FLASHBACK
INSIDE BLOOD COMMENTARIES
BLOOD FORUM
BLOOD SPOTLIGHT
HOW I TREAT
CLINICAL TRIALS AND OBSERVATIONS
Ibrutinib efficacy and tolerability in patients with relapsed chronic lymphocytic leukemia following allogeneic HCT
Clinical Trials & Observations
Christine E. Ryan,Bita Sahaf,Aaron C. Logan,Susan O’Brien,John C. Byrd,Peter Hillmen,Jennifer R. Brown,Martin J. S. Dyer,Anthony R. Mato,Michael J. Keating,Samantha Jaglowski,Fong Clow,Andrew R. Rezvani,Lori Styles,Steven E. Coutre,David B. Miklos
IMMUNOBIOLOGY
LYMPHOID NEOPLASIA
High-level ROR1 associates with accelerated disease progression in chronic lymphocytic leukemia
Clinical Trials & Observations
Bing Cui,Emanuela M. Ghia,Liguang Chen,Laura Z. Rassenti,Christopher DeBoever,George F. Widhopf, II,Jian Yu,Donna S. Neuberg,William G. Wierda,Kanti R. Rai,Neil E. Kay,Jennifer R. Brown,Jeffrey A. Jones,John G. Gribben,Kelly A. Frazer,Thomas J. Kipps
Serum free light chains, not urine specimens, should be used to evaluate response in light-chain multiple myeloma
CME
Thomas Dejoie,Jill Corre,Helene Caillon,Cyrille Hulin,Aurore Perrot,Denis Caillot,Eileen Boyle,Marie-Lorraine Chretien,Jean Fontan,Karim Belhadj,Sabine Brechignac,Olivier Decaux,Laurent Voillat,Philippe Rodon,Olivier Fitoussi,Carla Araujo,Lotfi Benboubker,Charlotte Fontan,Mourad Tiab,Pascal Godmer,Odile Luycx,Olivier Allangba,Jean-Michel Pignon,Jean-Gabriel Fuzibet,Laurence Legros,Anne Marie Stoppa,Mamoun Dib,Brigitte Pegourie,Frederique Orsini-Piocelle,Lionel Karlin,Bertrand Arnulf,Murielle Roussel,Laurent Garderet,Mohamad Mohty,Nathalie Meuleman,Chantal Doyen,Pascal Lenain,Margaret Macro,Xavier Leleu,Thierry Facon,Philippe Moreau,Michel Attal,Herve Avet-Loiseau
MYELOID NEOPLASIA
Establishing human leukemia xenograft mouse models by implanting human bone marrow–like scaffold-based niches
Antonella Antonelli,Willy A. Noort,Jenny Jaques,Bauke de Boer,Regina de Jong-Korlaar,Annet Z. Brouwers-Vos,Linda Lubbers-Aalders,Jeroen F. van Velzen,Andries C. Bloem,Huipin Yuan,Joost D. de Bruijn,Gert J. Ossenkoppele,Anton C. M. Martens,Edo Vellenga,Richard W. J. Groen,Jan Jacob Schuringa
The NLRP3 inflammasome functions as a driver of the myelodysplastic syndrome phenotype
Ashley A. Basiorka,Kathy L. McGraw,Erika A. Eksioglu,Xianghong Chen,Joseph Johnson,Ling Zhang,Qing Zhang,Brittany A. Irvine,Thomas Cluzeau,David A. Sallman,Eric Padron,Rami Komrokji,Lubomir Sokol,Rebecca C. Coll,Avril A. B. Robertson,Matthew A. Cooper,John L. Cleveland,Luke A. O’Neill,Sheng Wei,Alan F. List
RED CELLS, IRON, AND ERYTHROPOIESIS
A new molecular link between defective autophagy and erythroid abnormalities in chorea-acanthocytosis
Francesca Lupo,Elena Tibaldi,Alessandro Matte,Alok K. Sharma,Anna Maria Brunati,Seth L. Alper,Carlo Zancanaro,Donatella Benati,Angela Siciliano,Mariarita Bertoldi,Francesca Zonta,Alexander Storch,Ruth H. Walker,Adrian Danek,Benedikt Bader,Andreas Hermann,Lucia De Franceschi
TRANSPLANTATION
Erythropoietin modulation is associated with improved homing and engraftment after umbilical cord blood transplantation
Omar S. Aljitawi,Soumen Paul,Avishek Ganguly,Tara L. Lin,Sid Ganguly,George Vielhauer,Maegan L. Capitano,Amy Cantilena,Brea Lipe,Jonathan D. Mahnken,Amanda Wise,Abigale Berry,Anurag K. Singh,Leyla Shune,Christopher Lominska,Sunil Abhyankar,Dennis Allin,Mary Laughlin,Joseph P. McGuirk,Hal E. Broxmeyer
BLOOD WORK
ERRATUM
CONTINUING MEDICAL EDUCATION (CME) QUESTIONS
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Cover Image
Cover Image
Scaffold implants coated with mesenchymal stromal cells generate an ectopic hematopoietic niche. The image shows implants before inoculation with acute myeloid leukemia cells. Scaffolds are stained brown. Bone and stromal cells and blood vessels are stained pink (hematoxylin and eosin stain). See the article by Antonelli et al on page 2949.
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