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Axel Künstner
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Journal Articles

Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy

Daria Frank, Pradeep Kumar Patnana, Jan Vorwerk, Lianghao Mao, Lavanya Mokada Gopal, Noelle Jung, Thorben Hennig, Leo Ruhnke, Joris Maximillian Frenz, Maithreyan Kuppusamy, Robert Autry, Lanying Wei, Kaiyan Sun, Helal Mohammed Mohammed Ahmed, Axel Künstner, Hauke Busch, Heiko Müller, Stephan Hutter, Gregor Hoermann, Longlong Liu, Xiaoqing Xie, Yahya Al-Matary, Subbaiah Chary Nimmagadda, Fiorella Charles Cano, Michael Heuser, Felicitas Thol, Gudrun Göhring, Doris Steinemann, Jürgen Thomale, Theo Leitner, Anja Fischer, Roland Rad, Christoph Röllig, Heidi Altmann, Desiree Kunadt, Wolfgang E. Berdel, Jana Hüve, Felix Neumann, Jürgen Klingauf, Virginie Calderon, Bertram Opalka, Ulrich Dührsen, Frank Rosenbauer, Martin Dugas, Julian Varghese, Hans Christian Reinhardt, Nikolas von Bubnoff, Tarik Möröy, Georg Lenz, Aarif M. N. Batcha, Marianna Giorgi, Murugan Selvam, Eunice Wang, Shannon K. McWeeney, Jeffrey W. Tyner, Friedrich Stölzel, Matthias Mann, Ashok Kumar Jayavelu, Cyrus Khandanpour
Journal: Blood
Blood (2023) 142 (25): 2175–2191.
https://doi.org/10.1182/blood.2022015752
Published: 2023
Includes: Supplemental data
Journal Articles

Mutational Changes in Solid Cancer Cells Induce DNA Damage Repair Deficiency in Hematopoietic Cells Leading to a Distinct Spectrum of Clonal Hematopoiesis Independent from Age-Related Clonal Hematopoiesis

Theo Leitner, Axel Künstner, Michael Kohl, Tobias Barmwater, Helal Mohammed Ahmed, Almuth Caliebe, Eva Dazert-Klebsattel, Anke Fähnrich, Stephanie Fliedner, Niklas Gebauer, Malte Spielmann, Jutta Kirfel, Verena-Wilbeth Sailer, Lorenz Bastian, Nikolas Von Bubnoff, Hauke Busch, Cyrus Khandanpour
Journal: Blood
Blood (2023) 142 (Supplement 1): 5605.
https://doi.org/10.1182/blood-2023-184994
Published: 2023
Journal Articles

Genome-Wide DNA Methylation Profiling in Blastic Plasmacytoid Dendritic Cell Neoplasm

Hanno M. Witte, Axel Künstner, Julian Schwarting, Veronica Bernard, Stephanie Stölting, Nikolas von Bubnoff, Eva Penas, Hartmut Merz, Reiner Siebert, Hauke Busch, Alfred Feller, Niklas Gebauer
Journal: Blood
Blood (2022) 140 (Supplement 1): 11496–11497.
https://doi.org/10.1182/blood-2022-162212
Published: 2022
Journal Articles

Gain-of-function mutations in RPA1 cause a syndrome with short telomeres and somatic genetic rescue

Clinical Trials & Observations
Richa Sharma, Sushree S. Sahoo, Masayoshi Honda, Sophie L. Granger, Charnise Goodings, Louis Sanchez, Axel Künstner, Hauke Busch, Fabian Beier, Shondra M. Pruett-Miller, Marcus B. Valentine, Alfonso G. Fernandez, Ti-Cheng Chang, Vincent Géli, Dmitri Churikov, Sandrine Hirschi, Victor B. Pastor, Melanie Boerries, Melchior Lauten, Charikleia Kelaidi, Megan A. Cooper, Sarah Nicholas, Jill A. Rosenfeld, Sophia Polychronopoulou, Caroline Kannengiesser, Carole Saintomé, Charlotte M. Niemeyer, Patrick Revy, Marc S. Wold, Maria Spies, Miriam Erlacher, Stéphane Coulon, Marcin W. Wlodarski
Journal: Blood
Blood (2022) 139 (7): 1039–1051.
https://doi.org/10.1182/blood.2021011980
Published: 2022
Includes: Supplemental data