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Journal Articles

Development of a Novel L-Asparaginase with Enhanced Properties Using Ancestral Sequence Reconstruction

Kristopher A Knight, Harrison C. Brown, Kinnede R. White, H. Trent Spencer, Christopher B Doering, Sunil S. Raikar

Blood (2023) 142 (Supplement 1): 4191.

https://doi.org/10.1182/blood-2023-190281

Published: 2023

Journal Articles

Erythrocyte Intracellular Adenosine Regulates Oxygen Release Combating Tissue Hypoxia, Inflammation and Fibrosis

Changhan Chen, Tingting Xie, Yujin Zhang, Yiyan Wang, Fang Yu, Lizhen Lin, Weiru Zhang, Benjamin C. Brown, Xin Zhang, Rodney E. Kellems, Angelo D'Alessandro, Yang Xia

Blood (2023) 142 (Supplement 1): 2457.

https://doi.org/10.1182/blood-2023-190862

Published: 2023

Journal Articles

Beneficial Role of Erythrocyte Sphingosine 1-Phosphate in Preventing Renal Macrophage Polarization and Fibrosis through Combating HIF-1α-Dependent Creatine Phosphate Shuttle

Tingting Xie, Changhan Chen, Yiyan Wang, Zhenjiang Li, Benjamin C. Brown, Rodney E. Kellems, Weiru Zhang, Angelo D'Alessandro, Yang Xia

Blood (2023) 142 (Supplement 1): 3918.

https://doi.org/10.1182/blood-2023-191038

Published: 2023

Journal Articles

BAX Mutated Clonal Hematopoiesis Arises Following Treatment with the BCL2 Inhibitor Class of Therapeutics across a Range of Hematological and Non-Hematological Neoplasms

Ing Soo Tiong, Tamia Nguyen, Charis Teh, Chong Chyn Chua, Sarah Ftouni, Thomas E Lew, Fiona C. Brown, Donia Moujalled, Christine Muttiah, Daniel Gray, Mary Ann Anderson, Philip A. Thompson, Constantine S. Tam, John F. Seymour, Sarah-Jane Dawson, Andrew H. Wei, Geoffrey Lindeman, Piers Blombery

Blood (2023) 142 (Supplement 1): 2688.

https://doi.org/10.1182/blood-2023-180386

Published: 2023

Journal Articles

Venetoclax Has Potent Efficacy in NPM1 mutated AML with Acquired Resistance Associated with Either Perturbed Pro-Survival Signalling or NPM1 wild-Type Populations

Blood (2023) 142 (Supplement 1): 423.

https://doi.org/10.1182/blood-2023-185321

Published: 2023

Journal Articles

Direct, Potent, and TP53-Independent Activity of Sting Agonists Against Acute Myeloid Leukaemia Enhances Venetoclax Efficacy In Vivo

Yin Yuan, Sarah T Diepstraten, Fiona C. Brown, Veronique Litalien, Andreas Strasser, Gemma L Kelly, Andrew W. Roberts, Andrew H. Wei

Blood (2023) 142 (Supplement 1): 4163.

https://doi.org/10.1182/blood-2023-179698

Published: 2023

Journal Articles

Is BCL-xL the Achilles' heel of AEL and AMKL?

Fiona C. Brown, Andrew H. Wei

Blood (2023) 141 (13): 1505–1506.

https://doi.org/10.1182/blood.2022019246

Published: 2023

Journal Articles

Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemia

Blood (2023) 141 (6): 634–644.

https://doi.org/10.1182/blood.2022016090

Published: 2023

Includes: Supplemental data

Journal Articles

Long-term follow-up of liver-directed, adeno-associated vector-mediated gene therapy in the canine model of hemophilia A

P. Batty, A. M. Mo, D. Hurlbut, J. Ishida, B. Yates, C. Brown, L. Harpell, C. Hough, A. Pender, E. K. Rimmer, S. Sardo Infirri, A. Winterborn, S. Fong, D. Lillicrap

Blood (2022) 140 (25): 2672–2683.

https://doi.org/10.1182/blood.2021014735

Published: 2022

Includes: Supplemental data

Journal Articles

Erythrocyte Sphingosine 1 Phosphate Is Essential to Combat HIF1α-Dependent Creatine Shuttle, Macrophage Polarization and Fibrosis

Tingting Xie, Weiru Zhang, Changhan Chen, Benjamin C Brown, Jacob Couturier, Angelo D'Alessandro, Rodney E. Kellems, Yang Xia

Blood (2022) 140 (Supplement 1): 40–41.

https://doi.org/10.1182/blood-2022-168654

Published: 2022

Journal Articles

ENT1-AMPD3 As an Imperative Erythrocyte Hypoxia Sensor and Metabolic Regulator Combats Tissue Hypoxia and Fibrosis

Changhan Chen, Tingting Xie, Yujin Zhang, Weiru Zhang, Benjamin C Brown, Xin Zhang, Rodney Kellems, Angelo D'Alessandro, Yang Xia

Blood (2022) 140 (Supplement 1): 5321–5322.

https://doi.org/10.1182/blood-2022-168885

Published: 2022

Journal Articles

Quantitative Platelet Adhesion and Platelet Geometry-Sensing Assays for Evaluating Mild Bleeding Disorders

Sally Azer, Oluwamayokun Oshinowo, Meredith E. Fay, Yumiko Sakurai, Megan C. Brown, Carolyn Bennett, Shannon L. Meeks, Wilbur A. Lam

Blood (2022) 140 (Supplement 1): 5538–5539.

https://doi.org/10.1182/blood-2022-162598

Published: 2022

Journal Articles

The AP-1/ETS Transcription Factor Network Regulates Stem Cell Quiescence and Chemotherapy Resistance in Acute Myeloid Leukemia

Sumiko Takao, Victor Morell, Fiona C. Brown, Richard Koche, Alex Kentsis

Blood (2022) 140 (Supplement 1): 8682–8683.

https://doi.org/10.1182/blood-2022-165325

Published: 2022

Journal Articles

Introducing a Novel Biophysical Platelet Function Panel to Investigate Disorders of Primary Hemostasis and Bleeding of Unknown Cause

Sally Azer, Oluwamayokun Oshinowo, Meredith E. Fay, Yumiko Sakurai, Yongzhi Qiu, Carolyn M. Bennett, Shannon Meeks, Megan C. Brown, David R. Myers, Wilbur A. Lam

Blood (2021) 138 (Supplement 1): 2072.

https://doi.org/10.1182/blood-2021-153324

Published: 2021

Journal Articles

Pharmacological Reduction of Mitochondrial Iron in AML Triggers a BAX/BAK Dependent Non-Canonical Cell Death Synergistic with Venetoclax

Blood (2021) 138 (Supplement 1): 267.

https://doi.org/10.1182/blood-2021-145424

Published: 2021

Journal Articles

Ex Vivo and In Vivo Evaluation of Fibrinogen Concentrate to Mitigate Post-Surgical Bleeding in Neonates

Nina Moiseiwitsch, Kimberly A Nellenbach, Nina A Guzzetta, Ashley C Brown, Laura Downey

Blood (2021) 138 (Supplement 1): 1034.

https://doi.org/10.1182/blood-2021-153823

Published: 2021

Journal Articles

Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias

Blood (2021) 137 (20): 2721–2735.

https://doi.org/10.1182/blood.2020010167

Published: 2021

Includes: Supplemental data

Journal Articles

Acquired Mutations in BAX Confer Resistance to BH3 Mimetics in Acute Myeloid Leukemia

Blood (2020) 136 (Supplement 1): 7–8.

https://doi.org/10.1182/blood-2020-136872

Published: 2020

Journal Articles

Differential Sialic Acid Content in Adult and Neonatal Fibrinogen Mediate Differences in Clot Polymerization

Kimberly A Nellenbach, Nina A Guzzetta, MD FAAP, Ashley C Brown, PhD

Blood (2020) 136 (Supplement 1): 21–22.

https://doi.org/10.1182/blood-2020-139965

Published: 2020

Journal Articles

Platelet Function Analyzer-100 Shows Poor Predictive Value for Children with Low VWF and Mild Platelet Function Defects

Megan C. Brown, MD MSc, Gary Woods, MD

Blood (2020) 136 (Supplement 1): 28–29.

https://doi.org/10.1182/blood-2020-142103

Published: 2020

NARROW

Development of a Novel L-Asparaginase with Enhanced Properties Using Ancestral Sequence Reconstruction

Erythrocyte Intracellular Adenosine Regulates Oxygen Release Combating Tissue Hypoxia, Inflammation and Fibrosis

Beneficial Role of Erythrocyte Sphingosine 1-Phosphate in Preventing Renal Macrophage Polarization and Fibrosis through Combating HIF-1α-Dependent Creatine Phosphate Shuttle

BAX Mutated Clonal Hematopoiesis Arises Following Treatment with the BCL2 Inhibitor Class of Therapeutics across a Range of Hematological and Non-Hematological Neoplasms

Venetoclax Has Potent Efficacy in NPM1 mutated AML with Acquired Resistance Associated with Either Perturbed Pro-Survival Signalling or NPM1 wild-Type Populations

Direct, Potent, and TP53-Independent Activity of Sting Agonists Against Acute Myeloid Leukaemia Enhances Venetoclax Efficacy In Vivo

Is BCL-xL the Achilles' heel of AEL and AMKL?

Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemia

Long-term follow-up of liver-directed, adeno-associated vector-mediated gene therapy in the canine model of hemophilia A

Erythrocyte Sphingosine 1 Phosphate Is Essential to Combat HIF1α-Dependent Creatine Shuttle, Macrophage Polarization and Fibrosis

ENT1-AMPD3 As an Imperative Erythrocyte Hypoxia Sensor and Metabolic Regulator Combats Tissue Hypoxia and Fibrosis

Quantitative Platelet Adhesion and Platelet Geometry-Sensing Assays for Evaluating Mild Bleeding Disorders

The AP-1/ETS Transcription Factor Network Regulates Stem Cell Quiescence and Chemotherapy Resistance in Acute Myeloid Leukemia

Introducing a Novel Biophysical Platelet Function Panel to Investigate Disorders of Primary Hemostasis and Bleeding of Unknown Cause

Pharmacological Reduction of Mitochondrial Iron in AML Triggers a BAX/BAK Dependent Non-Canonical Cell Death Synergistic with Venetoclax

Ex Vivo and In Vivo Evaluation of Fibrinogen Concentrate to Mitigate Post-Surgical Bleeding in Neonates

Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias

Acquired Mutations in BAX Confer Resistance to BH3 Mimetics in Acute Myeloid Leukemia

Differential Sialic Acid Content in Adult and Neonatal Fibrinogen Mediate Differences in Clot Polymerization

Platelet Function Analyzer-100 Shows Poor Predictive Value for Children with Low VWF and Mild Platelet Function Defects

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American Society of Hematology

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American Society of Hematology

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