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Journal Articles

Proposals for revised International Working Group–European LeukemiaNet criteria for anemia response in myelofibrosis

Brief Report
Ayalew Tefferi, Giovanni Barosi, Francesco Passamonti, Juan-Carlos Hernandez-Boluda, Prithviraj Bose, Konstanze Döhner, Martin Ellis, Naseema Gangat, Jacqueline S. Garcia, Heinz Gisslinger, Jason Gotlib, Paola Guglielmelli, Vikas Gupta, Claire Harrison, Elizabeth O. Hexner, Gabriela S. Hobbs, Jean-Jacques Kiladjian, Steffen Koschmieder, Nicolaus Kroger, Andrew T. Kuykendall, Giuseppe G. Loscocco, John Mascarenhas, Lucia Masarova, Ruben Mesa, Barbara Mora, Olatoyosi Odenike, Stephen T. Oh, Animesh Pardanani, Anand Patel, Naveen Pemmaraju, Alessandro Rambaldi, Raajit Rampal, Shireen Sirhan, Natasha Szuber, Moshe Talpaz, Pankit J. Vachhani, Alessandro M. Vannucchi, Tiziano Barbui
Journal: Blood
Blood (2024) 144 (17): 1813–1820.
https://doi.org/10.1182/blood.2024025802
Published: 2024
Journal Articles

Asciminib plus dasatinib and prednisone for Philadelphia chromosome-positive acute leukemia

Clinical Trials & Observations
Marlise R. Luskin, Mark Alan Murakami, Julia H. Keating, Yael Flamand, Eric S Winer, Jacqueline S. Garcia, Maximilian Stahl, Richard M. Stone, Martha Wadleigh, Stella Louise Jaeckle, Ella Hagopian, David M. Weinstock, Jessica Liegel, Malgorzata McMasters, Eunice S Wang, Wendy Stock, Daniel J DeAngelo
Journal: Blood
Blood blood.2024025800.
https://doi.org/10.1182/blood.2024025800
Published: 2024
Includes: Supplemental data
Journal Articles

CRISPR-based rapid molecular diagnostic tests for fusion-driven leukemias

Rahul S. Vedula, Hannah Q. Karp, Jeremy Koob, Felicia Lim, Jacqueline S. Garcia, Eric S. Winer, Marlise R. Luskin, Gabriel Ghiaur, Annette S. Kim, Lan W. Beppu, Olga Sala-Torra, Jerald Radich, Jonathan Gootenberg, Omar Abudayyeh, Feng Zhang, R. Coleman Lindsley
Journal: Blood
Blood (2024) 144 (12): 1290–1299.
https://doi.org/10.1182/blood.2023022908
Published: 2024
Includes: Supplemental data
Journal Articles

Post-Transplant T Cell Clonotype Diversity Is Associated with Survival in Patients with TP53-Mutated Acute Myeloid Leukemia

Nurefsan Sariipek, Kseniia R. Safina, Corey Cutler, Vincent T. Ho, John Koreth, Coleman Lindsley, Marlise R. Luskin, Jacqueline S. Garcia, Doreen Hearsey, Wesley S Lu, Shuqiang Li, Kenneth J. Livak, Gabriel K. Griffin, Robert J. Soiffer, Jerome Ritz, Catherine J Wu, Joseph H. Antin, Andrew A. Lane, Peter Van Galen, Mahasweta Gooptu
Journal: Blood
Blood (2023) 142 (Supplement 1): 2176.
https://doi.org/10.1182/blood-2023-181863
Published: 2023
Journal Articles

A Phase 2 Study of Lenalidomide in Combination with Mitoxantrone, Etoposide, and Cytarabine (Len plus MEC) in Patients with Relapsed or Refractory Acute Myeloid Leukemia

Manik Razdan Kuchroo, Robert A. Redd, Jacqueline S. Garcia, Michael Keng, Gabriela S. Hobbs, Jacalyn Rosenblatt, Marlise R. Luskin, Rupa Narayan, Philip C. Amrein, Malgorzata McMasters, Martha Wadleigh, Hanno Hock, Richard Stone, Donna S. Neuberg, David Avigan, Karen K. Ballen, Amir T. Fathi, Daniel J. DeAngelo, Andrew M. Brunner
Journal: Blood
Blood (2023) 142 (Supplement 1): 2894.
https://doi.org/10.1182/blood-2023-188182
Published: 2023
Journal Articles

Mini-Hyper-CVD Plus Venetoclax for Treatment of Older Adults with Newly Diagnosed Ph-Negative B-ALL or T-ALL

Marlise R. Luskin, Shai Shimony, Julia Keating, Wendy Stock, Hanno Hock, Jacqueline S. Garcia, Maximilian Stahl, Ilene Galinksy, Rebecca Leonard, Howard Weiner, Yael Flamand, Donna S. Neuberg, Richard M Stone, Anthony G. Letai, Eric S. Winer, Marina Y. Konopleva, Nitin Jain, Daniel J. DeAngelo
Journal: Blood
Blood (2023) 142 (Supplement 1): 2875.
https://doi.org/10.1182/blood-2023-174269
Published: 2023
Journal Articles

Outcomes in Chemotherapy-Ineligible Elderly Patients with Newly Diagnosed Acute Myeloid Leukemia Treated with Venetoclax Plus Azacitidine: A Pooled Analysis

Adriano Venditti, Jing-Zhou Hou, Pierre Fenaux, Brian A. Jonas, Radovan Vrhovac, Pau Montesinos, Jacqueline S. Garcia, David Rizzieri, Michael J Thirman, Stanley Kotey, Jalaja Potluri, Mazaher Dhalla, Vinod Pullarkat
Journal: Blood
Blood (2023) 142 (Supplement 1): 2886.
https://doi.org/10.1182/blood-2023-182045
Published: 2023
Journal Articles

Tagraxofusp in Combination with Azacitidine and Venetoclax in Newly Diagnosed CD123+ Acute Myeloid Leukemia, Expansion Cohort of a Phase 1b Multicenter Trial

Andrew A. Lane, Jacqueline S. Garcia, Evangeline G. Raulston, Jada L. Garzon, Ilene Galinsky, Emilie W. Baxter, Rebecca Leonard, Daniel J. DeAngelo, Marlise R. Luskin, Christopher R. Reilly, Maximilian Stahl, Richard M Stone, Rahul Vedula, Martha Wadleigh, Eric S. Winer, Tariq Mughal, Christopher Brooks, Ira V. Gupta, Kristen E. Stevenson, Donna S. Neuberg, Siyang Ren, Marina Y. Konopleva, Anthony Stein, Naveen Pemmaraju
Journal: Blood
Blood (2023) 142 (Supplement 1): 4277.
https://doi.org/10.1182/blood-2023-180010
Published: 2023
Journal Articles

Comparative Analysis of Clinical Outcomes and Healthcare Resource Utilization (HRU) in Patients (Pts) with Newly Diagnosed (ND) Acute Myeloid Leukemia (AML) Unfit for High-Intensity Chemotherapy Treated with Venetoclax (VEN) Vs Other Therapies: Results from the AML Real World Evidence (ARC) Initiative

Pinkal Desai, Jacqueline S. Garcia, Joshua F. Zeidner, Sameem Abedin, Ofir Wolach, Pankit Vachhani, Yakir Moshe, Daniel A. Pollyea, Catherine Lai, Thomas W LeBlanc, Marin Xavier, Boaz Nachmias, Evan C. Chen, Srilakshmi Bathini, Inderpreet Bhatti, Cat N. Bui, Annie Guérin, Rebecca Burne, Esprit Ma, Moshe Grunspan, Neta Frankel, Aaron D. Goldberg
Journal: Blood
Blood (2023) 142 (Supplement 1): 5173.
https://doi.org/10.1182/blood-2023-173283
Published: 2023
Journal Articles

Venous Thromboembolism in Adolescents and Young Adults with Acute Lymphoblastic Leukemia Treated on a Pediatric-Inspired Regimen

Hari S. Raman, Shai Shimony, Yannis K. Valtis, Yael Flamand, Andrew E. Place, Lewis B. Silverman, Stephen E. Sallan, Lynda M. Vrooman, Andrew M. Brunner, Donna S. Neuberg, Ilene Galinsky, Jacqueline S. Garcia, Eric S. Winer, Martha Wadleigh, Richard M Stone, Jean M. Connors, Daniel J. DeAngelo, Marlise R. Luskin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1456.
https://doi.org/10.1182/blood-2023-178353
Published: 2023
Journal Articles

Integrative Single-Cell Tracking of Clonal Evolution, Leukemia Phenotypes and Donor Engraftment Following Allogeneic Stem Cell Transplant Using Mitochondrial DNA Mutations

Livius Penter, Nicoletta Cieri, Katie Maurer, Haoxiang Lyu, Wesley S Lu, Giacomo Oliveira, Satyen H Gohil, Caleb Lareau, Leif S Ludwig, Shuqiang Li, Jerome Ritz, Jacqueline S. Garcia, Robert J. Soiffer, Kenneth J. Livak, Catherine J Wu
Journal: Blood
Blood (2023) 142 (Supplement 1): 3580.
https://doi.org/10.1182/blood-2023-180113
Published: 2023
Journal Articles

Efficacy and Safety of Venetoclax in Combination with Azacitidine for the Treatment of Patients with Treatment-Naive, Higher-Risk Myelodysplastic Syndromes

Jacqueline S. Garcia, Uwe Platzbecker, Olatoyosi Odenike, Shaun Fleming, Chun Yew Fong, Rachel Cook, Meagan Jacoby, Daniel Nowak, Brenda Chyla, Ying Zhou, Grace Ku, Jalaja Potluri, Guillermo Garcia-Manero
Journal: Blood
Blood (2023) 142 (Supplement 1): 319.
https://doi.org/10.1182/blood-2023-189446
Published: 2023
Journal Articles

Impact of Clinical and Genetic Factors on Myelofibrosis Outcomes after Allogeneic Transplantation

Mahasweta Gooptu, Haesook T. Kim, Kaina Chen, Ann Mullally, Joseph Antin, Corey Cutler, Amar H Kelkar, John Koreth, Roman M. Shapiro, Robert J. Soiffer, Daniel J. DeAngelo, Jacqueline S. Garcia, Marlise R. Luskin, Richard M Stone, Martha Wadleigh, Eric S. Winer, R. Coleman Lindsley, Vincent Ho
Journal: Blood
Blood (2023) 142 (Supplement 1): 4978.
https://doi.org/10.1182/blood-2023-178684
Published: 2023
Journal Articles

Tracking of Leukemia and Immune Single Cell Phenotypes during Ipilimumab-Based Treatment By Long-Read Sequencing

Livius Penter, Mehdi Borji, Adi Nagler, Haoxiang Lyu, Wesley S Lu, Nicoletta Cieri, Alexandria Maurer, Giacomo Oliveira, Aziz M. Al'Khafaji, Kiran Garimella, Shuqiang Li, Donna S. Neuberg, Jerome Ritz, Robert J. Soiffer, Jacqueline S. Garcia, Kenneth J. Livak, Catherine J Wu
Journal: Blood
Blood (2023) 142 (Supplement 1): 1596.
https://doi.org/10.1182/blood-2023-180016
Published: 2023
Journal Articles

Phase 1 Study of BXCL701, a Dipeptidyl Peptidase Inhibitor, in Relapsed/Refractory Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndrome

Eric S. Winer, Jacqueline S. Garcia, Richard M Stone, Martha Wadleigh, Marlise R. Luskin, Maximilian Stahl, Evan C. Chen, Rebecca Leonard, Alexis Noyes, Ilene Galinsky, Rashmi Deshpande, Pascal Borderies, Vincent O'Neill, Daniel J. DeAngelo
Journal: Blood
Blood (2023) 142 (Supplement 1): 1549.
https://doi.org/10.1182/blood-2023-186598
Published: 2023
Journal Articles

Outcomes of Patients with Accelerated/Blast-Phase MPNs That Received Allogeneic Stem-Cell Transplant in the Current Era of Myeloid Therapies

Anand Ashwin Patel, James J. Yoon, Hannah Johnston, Marta Beata Davidson, Auro Viswabandya, Rory M. Shallis, Evan C. Chen, Madelyn Burkart, Timothy S. Oh, Sunil G. Iyer, Ellen Madarang, Chandrasekar Muthiah, Raven Dean, Joshua Kassner, Raajit K. Rampal, Guru Subramanian Guru Murthy, Terrence Bradley, Yasmin Abaza, Jacqueline S. Garcia, Vikas Gupta, Kristen Marie Pettit, John Cursio, Olatoyosi Odenike
Journal: Blood
Blood (2023) 142 (Supplement 1): 3192.
https://doi.org/10.1182/blood-2023-174790
Published: 2023
Journal Articles

A Phase I Study of Venetoclax in Combination with Inotuzumab Ozogamicin for Relapsed or Refractory ALL in Adults

Marlise R. Luskin, Shai Shimony, Julia Keating, Yael Flamand, Jacqueline S. Garcia, Rebecca Leonard, Thomas Reardon, Taylor Robertson, Chase M Weizer, Ilene Galinsky, Donna S. Neuberg, Richard M Stone, Eric S. Winer, Anthony G. Letai, Mark Alan Murakami, Daniel J. DeAngelo
Journal: Blood
Blood (2023) 142 (Supplement 1): 1509.
https://doi.org/10.1182/blood-2023-174216
Published: 2023
Journal Articles

A Simple Prediction Model of Outcomes after Allogeneic Hematopoietic Stem Cell Transplant (HCT) in Myelodysplastic Syndromes Using HCT-Comorbidity Index, Cytogenetic Risk, and Platelet Count

Stacey M Frumm, Haesook T. Kim, Amar H Kelkar, Vincent T. Ho, Mahasweta Gooptu, Christopher James Gibson, John Koreth, Roman M. Shapiro, Rizwan Romee, Sarah Nikiforow, Joseph H. Antin, Robert J. Soiffer, Benjamin Rolles, Shai Shimony, Jan Philipp Bewersdorf, Tariq Kewan, Abdulrahman Alhajahjeh, Marlise R. Luskin, Jacqueline S. Garcia, Evan C. Chen, Andrew A. Lane, Martha Wadleigh, Eric S. Winer, Richard M Stone, Daniel J. DeAngelo, Amer M. Zeidan, Coleman Lindsley, Corey Cutler, Maximilian Stahl
Journal: Blood
Blood (2023) 142 (Supplement 1): 2246.
https://doi.org/10.1182/blood-2023-185315
Published: 2023
Journal Articles

Updated Results on a Multicenter Phase II Study of a Dose Intensified Pediatric Regimen in Adults with Acute Lymphoblastic Leukemia: The 06-254 DFCI ALL Consortium Trial

Yannis K. Valtis, Yael Flamand, Shai Shimony, Andrew E. Place, Lewis B. Silverman, Lynda M. Vrooman, Andrew M. Brunner, Stephen E. Sallan, Martha Wadleigh, Jacqueline S. Garcia, Eric S. Winer, Ilene Galinsky, Julie Bergeron, Julie Asch, Matthew D. Seftel, Richard M Stone, Marlise R. Luskin, Daniel J. DeAngelo
Journal: Blood
Blood (2023) 142 (Supplement 1): 4238.
https://doi.org/10.1182/blood-2023-181014
Published: 2023
Journal Articles

Targeting Mitochondrial Apoptotic Priming State to Personalize Therapy for Relapsed Acute Myeloid Leukemia

Elyse Olesinski, Karanpreet Bhatia, Chuqi Wang, Marissa Pioso, Shu Xuan Ng, Xiao Xian Lin, Vedant Sandhu, Binyam Yilma, Stephan Rainer Maximilian Bohl, Jeremy Ryan, Disha Malani, Marlise R. Luskin, Olli Kallioniemi, Kimmo Porkka, Allen Yeoh, Sophia Adamia, Wee Joo Chng, Motomi Osato, David M. Weinstock, Jacqueline S. Garcia, Anthony G. Letai, Shruti Bhatt
Journal: Blood
Blood (2023) 142 (Supplement 1): 48.
https://doi.org/10.1182/blood-2023-189156
Published: 2023