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Issue Archive

Volume 115, Issue 9
March 4 2010
Issue Cover

Table of Contents

INSIDE BLOOD

IMMUNOBIOLOGY
IVIg immune inhibitory activity: APC is key
Beng H. Chong,James J. H. Chong
View Articletitled, IVIg immune inhibitory activity: APC is key
PLATELETS & THROMBOPOIESIS
HIT: more than just heparin
Theodore E. Warkentin
View Articletitled, HIT: more than just heparin
TRANSFUSION MEDICINE
p38: signaling improved platelet storage?
Lea M. Beaulieu,Jane E. Freedman
View Articletitled, p38: signaling improved platelet storage?
TRANSPLANTATION
Separation of GVHD and GVL
Allan D. Hess
View Articletitled, Separation of GVHD and GVL

BLOOD WORK

Flower cells of leukemia
View Articletitled, Flower cells of leukemia

PLENARY PAPERS

Granzyme B is not required for regulatory T cell–mediated suppression of graft-versus-host disease
Sheng F. Cai,Xuefang Cao,Anjum Hassan,Todd A. Fehniger,Timothy J. Ley
View Articletitled, Granzyme B is not required for regulatory T cell–mediated suppression of graft-versus-host disease
Supplemental data

REVIEW ARTICLES

Memories that last forever: strategies for optimizing vaccine T-cell memory
Jeffrey D. Ahlers,Igor M. Belyakov
View Articletitled, Memories that last forever: strategies for optimizing vaccine T-cell memory

CLINICAL TRIALS AND OBSERVATIONS

Very long-term outcome of acute promyelocytic leukemia after treatment with all-trans retinoic acid and chemotherapy: the European APL Group experience
Clinical Trials & Observations
Lionel Adès,Agnes Guerci,Emmanuel Raffoux,Miguel Sanz,Patrice Chevallier,Simona Lapusan,Christian Recher,Xavier Thomas,Consuelo Rayon,Sylvie Castaigne,Olivier Tournilhac,Stephane de Botton,Norbert Ifrah,Jean-Yves Cahn,Eric Solary,Claude Gardin,Nathalie Fegeux,Dominique Bordessoule,Augustin Ferrant,Sandrine Meyer-Monard,Norbert Vey,Herve Dombret,Laurent Degos,Sylvie Chevret,Pierre Fenaux,for the European APL Group
View Articletitled, Very long-term outcome of acute promyelocytic leukemia after treatment with all-<em>trans</em> retinoic acid and chemotherapy: the European APL Group experience
Single-agent arsenic trioxide in the treatment of children with newly diagnosed acute promyelocytic leukemia
Clinical Trials & Observations
Jin Zhou,Yingmei Zhang,Jinmei Li,Xiaoxia Li,Jinxiao Hou,Yanqiu Zhao,Xiuhua Liu,Xueying Han,Longhu Hu,Shuye Wang,Yanhong Zhao,Ying Zhang,Shengjin Fan,Chengfang Lv,Limin Li,Lingling Zhu
View Articletitled, Single-agent arsenic trioxide in the treatment of children with newly diagnosed acute promyelocytic leukemia
A dynamic prognostic model to predict survival in primary myelofibrosis: a study by the IWG-MRT (International Working Group for Myeloproliferative Neoplasms Research and Treatment)
Clinical Trials & Observations
Francesco Passamonti,Francisco Cervantes,Alessandro Maria Vannucchi,Enrica Morra,Elisa Rumi,Arturo Pereira,Paola Guglielmelli,Ester Pungolino,Marianna Caramella,Margherita Maffioli,Cristiana Pascutto,Mario Lazzarino,Mario Cazzola,Ayalew Tefferi
View Articletitled, A dynamic prognostic model to predict survival in primary myelofibrosis: a study by the IWG-MRT (International Working Group for Myeloproliferative Neoplasms Research and Treatment)
Supplemental data

HEMATOPOIESIS AND STEM CELLS

Slug deficiency enhances self-renewal of hematopoietic stem cells during hematopoietic regeneration
Yan Sun,Lijian Shao,Hao Bai,Zack Z. Wang,Wen-Shu Wu
View Articletitled, Slug deficiency enhances self-renewal of hematopoietic stem cells during hematopoietic regeneration

IMMUNOBIOLOGY

Interleukin-24 inhibits the plasma cell differentiation program in human germinal center B cells
Ghyath Maarof,Laurence Bouchet-Delbos,Hélène Gary-Gouy,Ingrid Durand-Gasselin,Roman Krzysiek,Ali Dalloul
View Articletitled, Interleukin-24 inhibits the plasma cell differentiation program in human germinal center B cells
Supplemental data
Indirect inhibition of in vivo and in vitro T-cell responses by intravenous immunoglobulins due to impaired antigen presentation
Éric Aubin,Réal Lemieux,Renée Bazin
View Articletitled, Indirect inhibition of in vivo and in vitro T-cell responses by intravenous immunoglobulins due to impaired antigen presentation

LYMPHOID NEOPLASIA

Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia
Takaomi Sanda,Xiaoyu Li,Alejandro Gutierrez,Yebin Ahn,Donna S. Neuberg,Jennifer O'Neil,Peter R. Strack,Christopher G. Winter,Stuart S. Winter,Richard S. Larson,Harald von Boehmer,A. Thomas Look
View Articletitled, Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia
Supplemental data
IL-6 and MYC collaborate in plasma cell tumor formation in mice
Sebastian Rutsch,Vishala T. Neppalli,Dong-Mi Shin,Wendy DuBois,Herbert C. Morse, III,Hartmut Goldschmidt,Siegfried Janz
View Articletitled, IL-6 and MYC collaborate in plasma cell tumor formation in mice
Supplemental data
Circulating microvesicles in B-cell chronic lymphocytic leukemia can stimulate marrow stromal cells: implications for disease progression
Asish K. Ghosh,Charla R. Secreto,Traci R. Knox,Wei Ding,Debabrata Mukhopadhyay,Neil E. Kay
View Articletitled, Circulating microvesicles in B-cell chronic lymphocytic leukemia can stimulate marrow stromal cells: implications for disease progression
Supplemental data
Verification of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood
Brief Report
Rashmi B. Prasad,Fay J. Hosking,Jayaram Vijayakrishnan,Elli Papaemmanuil,Rolf Koehler,Mel Greaves,Eamonn Sheridan,Andreas Gast,Sally E. Kinsey,Tracy Lightfoot,Eve Roman,Malcolm Taylor,Kathy Pritchard-Jones,Martin Stanulla,Martin Schrappe,Claus R. Bartram,Richard S. Houlston,Rajiv Kumar,Kari Hemminki
View Articletitled, Verification of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood

MYELOID NEOPLASIA

Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia
John A. Pulikkan,Viola Dengler,Philomina S. Peramangalam,Abdul A. Peer Zada,Carsten Müller-Tidow,Stefan K. Bohlander,Daniel G. Tenen,Gerhard Behre
View Articletitled, Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia
Supplemental data
Aberrant immunophenotype of blasts in myelodysplastic syndromes is a clinically relevant biomarker in predicting response to growth factor treatment
Theresia M. Westers,Canan Alhan,Martine E. D. Chamuleau,Maurice J. D. L. van der Vorst,Corien Eeltink,Gert J. Ossenkoppele,Arjan A. van de Loosdrecht
View Articletitled, Aberrant immunophenotype of blasts in myelodysplastic syndromes is a clinically relevant biomarker in predicting response to growth factor treatment
Supplemental data

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability
Sasidhar Vemula,Jianjian Shi,Philip Hanneman,Lei Wei,Reuben Kapur
View Articletitled, ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability

PLATELETS AND THROMBOPOIESIS

The severity of trauma determines the immune response to PF4/heparin and the frequency of heparin-induced thrombocytopenia
Norbert Lubenow,Peter Hinz,Simone Thomaschewski,Theresia Lietz,Michael Vogler,Andrea Ladwig,Michael Jünger,Matthias Nauck,Sebastian Schellong,Kathrin Wander,Georg Engel,Axel Ekkernkamp,Andreas Greinacher
View Articletitled, The severity of trauma determines the immune response to PF4/heparin and the frequency of heparin-induced thrombocytopenia

RED CELLS, IRON, AND ERYTHROPOIESIS

Analysis of novel sph (spherocytosis) alleles in mice reveals allele-specific loss of band 3 and adducin in α-spectrin–deficient red cells
Raymond F. Robledo,Amy J. Lambert,Connie S. Birkenmeier,Marius V. Cirlan,Andreea Flavia M. Cirlan,Dean R. Campagna,Samuel E. Lux,Luanne L. Peters
View Articletitled, Analysis of novel <em>sph</em> (<em>spherocytosis</em>) alleles in mice reveals allele-specific loss of band 3 and adducin in α-spectrin–deficient red cells
Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5′ olfactory receptor gene cluster
Nadia Solovieff,Jacqueline N. Milton,Stephen W. Hartley,Richard Sherva,Paola Sebastiani,Daniel A. Dworkis,Elizabeth S. Klings,Lindsay A. Farrer,Melanie E. Garrett,Allison Ashley-Koch,Marilyn J. Telen,Supan Fucharoen,Shau Yin Ha,Chi-Kong Li,David H. K. Chui,Clinton T. Baldwin,Martin H. Steinberg
View Articletitled, Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5′ olfactory receptor gene cluster

THROMBOSIS AND HEMOSTASIS

Dengue virus–induced hemorrhage in a nonhuman primate model
Nattawat Onlamoon,Sansanee Noisakran,Hui-Mien Hsiao,Alexander Duncan,Francois Villinger,Aftab A. Ansari,Guey Chuen Perng
View Articletitled, Dengue virus–induced hemorrhage in a nonhuman primate model
Supplemental data

TRANSFUSION MEDICINE

p38 mitogen-activated protein kinase activation during platelet storage: consequences for platelet recovery and hemostatic function in vivo
Matthias Canault,Daniel Duerschmied,Alexander Brill,Lucia Stefanini,Daphne Schatzberg,Stephen M. Cifuni,Wolfgang Bergmeier,Denisa D. Wagner
View Articletitled, p38 mitogen-activated protein kinase activation during platelet storage: consequences for platelet recovery and hemostatic function in vivo
Supplemental data

TRANSPLANTATION

Combined effect of total nucleated cell dose and HLA match on transplantation outcome in 1061 cord blood recipients with hematologic malignancies
Juliet N. Barker,Andromachi Scaradavou,Cladd E. Stevens
View Articletitled, Combined effect of total nucleated cell dose and HLA match on transplantation outcome in 1061 cord blood recipients with hematologic malignancies
Allogeneic transplantation for therapy-related myelodysplastic syndrome and acute myeloid leukemia
Mark R. Litzow,Sergey Tarima,Waleska S. Pérez,Brian J. Bolwell,Mitchell S. Cairo,Bruce M. Camitta,Corey S. Cutler,Marcos de Lima,John F. DiPersio,Robert Peter Gale,Armand Keating,Hillard M. Lazarus,Selina Luger,David I. Marks,Richard T. Maziarz,Philip L. McCarthy,Marcelo C. Pasquini,Gordon L. Phillips,J. Douglas Rizzo,Jorge Sierra,Martin S. Tallman,Daniel J. Weisdorf
View Articletitled, Allogeneic transplantation for therapy-related myelodysplastic syndrome and acute myeloid leukemia
All Issues

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