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Issue Archive

Volume 121, Issue 7
February 14 2013
Blood Cover Image for Volume 121, Issue 7

Table of Contents

Inside Blood

INSIDE BLOOD
CAReful epitope selection matters
Rupert Handgretinger
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GENE THERAPY
Gene therapy targets XLP
A. H. Filipovich
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INSIDE BLOOD
UGT2B17 as a disease accelerator in CLL
Yiming Zhong,John C. Byrd
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RED CELLS, IRON, & ERYTHROPOIESIS
Inhibiting the hepcidin inhibitor for treatment of iron overload
Laura Silvestri
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TRANSPLANTATION
Location, location, location: advancing veto cell therapies
James C. Zimring
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Blood Work

Systemic mastocytosis
Sylvie Bouvier,Anne Arnaud
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Plenary Paper

GENE THERAPY
SAP gene transfer restores cellular and humoral immune function in a murine model of X-linked lymphoproliferative disease
Brief Report
Christine Rivat,Claire Booth,Maria Alonso-Ferrero,Michael Blundell,Neil J. Sebire,Adrian J. Thrasher,H. Bobby Gaspar
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Perspectives

The myth of the second remission of acute leukemia in the adult
Clinical Trials & Observations
Stephen J. Forman,Jacob M. Rowe
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Clinical Trials and Observations

FACS analysis of Stat3/5 signaling reveals sensitivity to G-CSF and IL-6 as a significant prognostic factor in pediatric AML: a Children's Oncology Group report
Clinical Trials & Observations
Michele S. Redell,Marcos J. Ruiz,Robert B. Gerbing,Todd A. Alonzo,Beverly J. Lange,David J. Tweardy,Soheil Meshinchi
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Hematopoiesis and Stem Cells

Induction of megakaryocyte differentiation drives nuclear accumulation and transcriptional function of MKL1 via actin polymerization and RhoA activation
Elenoe C. Smith,Alexandra M. Teixeira,Rachel C. Chen,Lin Wang,Yuan Gao,Katherine L. Hahn,Diane S. Krause
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Immunobiology

Control of regulatory T cells is necessary for vaccine-like effects of antiviral immunotherapy by monoclonal antibodies
Roudaina Nasser,Mireia Pelegrin,Marc Plays,Laurent Gros,Marc Piechaczyk
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Peptide length determines the outcome of TCR/peptide-MHCI engagement
Julia Ekeruche-Makinde,John J. Miles,Hugo A. van den Berg,Ania Skowera,David K. Cole,Garry Dolton,Andrea J. A. Schauenburg,Mai Ping Tan,Johanne M. Pentier,Sian Llewellyn-Lacey,Kim M. Miles,Anna M. Bulek,Mathew Clement,Tamsin Williams,Andrew Trimby,Mick Bailey,Pierre Rizkallah,Jamie Rossjohn,Mark Peakman,David A. Price,Scott R. Burrows,Andrew K. Sewell,Linda Wooldridge
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Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection
Edwin Leeansyah,Anupama Ganesh,Máire F. Quigley,Anders Sönnerborg,Jan Andersson,Peter W. Hunt,Ma Somsouk,Steven G. Deeks,Jeffrey N. Martin,Markus Moll,Barbara L. Shacklett,Johan K. Sandberg
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Distinct gene-expression profiles associated with the susceptibility of pathogen-specific CD4 T cells to HIV-1 infection
Haitao Hu,Martin Nau,Phil Ehrenberg,Agnes-Laurence Chenine,Camila Macedo,Yu Zhou,Z. John Daye,Zhi Wei,Maryanne Vahey,Nelson L. Michael,Jerome H. Kim,Mary Marovich,Silvia Ratto-Kim
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A catalytically inactive mutant of the deubiquitylase YOD-1 enhances antigen cross-presentation
Sharvan Sehrawat,Paul-Albert Koenig,Oktay Kirak,Christian Schlieker,Manuel Fankhauser,Hidde L. Ploegh
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Inhibitory KIR/HLA incompatibility between sexual partners confers protection against HIV-1 transmission
Wim Jennes,Sonja Verheyden,Julie W. Mertens,Makhtar Camara,Moussa Seydi,Tandakha N. Dieye,Souleymane Mboup,Christian Demanet,Luc Kestens
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Gene-expression signatures differ between different clinical forms of familial hemophagocytic lymphohistiocytosis
e-blood
Janos Sumegi,Shawnagay V. Nestheide,Michael G. Barnes,Joyce Villanueva,Kejian Zhang,Alexei A. Grom,Alexandra H. Filipovich
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Lymphoid Neoplasia

Anti-CD22–chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia
Waleed Haso,Daniel W. Lee,Nirali N. Shah,Maryalice Stetler-Stevenson,Constance M. Yuan,Ira H. Pastan,Dimiter S. Dimitrov,Richard A. Morgan,David J. FitzGerald,David M. Barrett,Alan S. Wayne,Crystal L. Mackall,Rimas J. Orentas
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Supplemental data
Overexpression of uridine diphospho glucuronosyltransferase 2B17 in high-risk chronic lymphocytic leukemia
Clinical Trials & Observations
Michaela Gruber,Judith Bellemare,Gregor Hoermann,Andreas Gleiss,Edit Porpaczy,Martin Bilban,Trang Le,Sonja Zehetmayer,Christine Mannhalter,Alexander Gaiger,Medhat Shehata,Karin Fleiss,Cathrin Skrabs,Éric Lévesque,Katrina Vanura,Chantal Guillemette,Ulrich Jaeger
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Telomere length in mantle cell lymphoma
Brief Report
Billy Michael Chelliah Jebaraj,Dirk Kienle,André Lechel,Daniel Mertens,Maria Heuberger,German Ott,Andreas Rosenwald,Thomas F. E. Barth,Peter Möller,Thorsten Zenz,Hartmut Döhner,Stephan Stilgenbauer
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Application of a new wall-less plate technology to complex multistep cell-based investigations using suspension cells
e-blood
Gabriel A. Quiñones,Travis I. Moore,Katrina Nicholes,Hyunjae Lee,Sudong Kim,Laura Sun,Noo Li Jeon,Jean-Philippe Stephan
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Myeloid Neoplasia

Differential effects of hydroxyurea and INC424 on mutant allele burden and myeloproliferative phenotype in a JAK2-V617F polycythemia vera mouse model
Lucia Kubovcakova,Pontus Lundberg,Jean Grisouard,Hui Hao-Shen,Vincent Romanet,Rita Andraos,Masato Murakami,Stephan Dirnhofer,Kay-Uwe Wagner,Thomas Radimerski,Radek C. Skoda
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Multiplexed mAbs: a new strategy in preclinical time-domain imaging of acute myeloid leukemia
e-blood
Emmet McCormack,Maja Mujić,Tereza Osdal,Øystein Bruserud,Bjørn Tore Gjertsen
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Red Cells, Iron, and Erythropoiesis

An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe−/− mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia
Paul J. Schmidt,Iva Toudjarska,Anoop K. Sendamarai,Tim Racie,Stuart Milstein,Brian R. Bettencourt,Julia Hettinger,David Bumcrot,Mark D. Fleming
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Thrombosis and Hemostasis

Dysfunction of the PI3 kinase/Rap1/integrin αIIbβ3 pathway underlies ex vivo platelet hypoactivity in essential thrombocythemia
Samantha F. Moore,Roger W. Hunter,Matthew T. Harper,Joshua S. Savage,Samreen Siddiq,Sarah K. Westbury,Alastair W. Poole,Andrew D. Mumford,Ingeborg Hers
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Transplantation

Murine anti–third-party central-memory CD8+ T cells promote hematopoietic chimerism under mild conditioning: lymph-node sequestration and deletion of anti-donor T cells
Eran Ophir,Noga Or-Geva,Irina Gurevich,Orna Tal,Yaki Eidelstein,Elias Shezen,Raanan Margalit,Assaf Lask,Guy Shakhar,David Hagin,Esther Bachar-Lustig,Shlomit Reich-Zeliger,Andreas Beilhack,Robert Negrin,Yair Reisner
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Vascular Biology

Evidence for the interaction of fibroblast growth factor-2 with the lymphatic endothelial cell marker LYVE-1
Natalia Platonova,Geraldine Miquel,Birgit Regenfuss,Said Taouji,Claus Cursiefen,Eric Chevet,Andreas Bikfalvi
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Correspondence

BCR-ABL1 is a secondary event after JAK2V617F in patients with polycythemia vera who develop chronic myeloid leukemia
Xiaoli Wang,Joseph Tripodi,Marina Kremyanskaya,Amanda Blouin,Paul Roda,Ronald Hoffman,Vesna Najfeld
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Hemichorea in a patient with JAK2V617F blood cells
Jane Lew,Steven J. Frucht,Marina Kremyanskaya,Ronald Hoffman,John Mascarenhas
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Supplemental data
No cross-resistance after sequential use of romiplostim and eltrombopag in chronic immune thrombocytopenic purpura
Giovanni D'Arena,Roberto Guariglia,Giovanna Mansueto,Maria Carmen Martorelli,Giuseppe Pietrantuono,Oreste Villani,Rosa Lerose,Pellegrino Musto
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C1-esterase inhibitor concentrate rescues erythrocytes from complement-mediated destruction in autoimmune hemolytic anemia
Diana Wouters,Femke Stephan,Paul Strengers,Masja de Haas,Conny Brouwer,Anton Hagenbeek,Marinus H. J. van Oers,Sacha Zeerleder
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All Issues

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