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Jaroslaw Maciejewski"
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Journal Articles

Aplastic Anemia in the Elderly: Treatment Patterns and Outcomes from an International Observational Study

Free
Bruno Fattizzo, Carmelo Gurnari, Sabrina Giammarco, Antony Ricchiuti, Hussein Awada, Marta Bortolotti, Giacinto Luca Pedone, Francesco Versino, Dario Consonni, Roochi Trikha, Shreyans Gandhi, Simona Sica, Jaroslaw Maciejewski, Austin G. Kulasekararaj, Wilma Barcellini
Journal: Blood
Blood (2024) 144 (Supplement 1): 4076.
https://doi.org/10.1182/blood-2024-198321
Published: 2024
Journal Articles

Clinical and Molecular Insights into the Classification Dilemma: Are MDS/AML Cases Distinct from Secondary AML?

Free
Tariq Kewan, Arda Durmaz, Waled Bahaj, Carmelo Gurnari, Olisaemeka Ogbue, Ahmad Kiwan, Hussein Awada, Hetty E. Carraway, Suresh Kumar Balasubramanian, Taha Bat, Yazan F Madanat, Valeria Visconte, Jaroslaw Maciejewski
Journal: Blood
Blood (2024) 144 (Supplement 1): 850.
https://doi.org/10.1182/blood-2024-207770
Published: 2024
Journal Articles

Clinical and Molecular Characteristics of RAS and RAS-like Mutational Signature in Acute Myeloid Leukemia

Free
Vikram Dhillon, Jeff Aguilar, Paul Kim, Dakshin Padmanabhan, Jay Yang, Gregory Dyson, David Carr, Jaroslaw Maciejewski, Suresh Kumar Balasubramanian
Journal: Blood
Blood (2024) 144 (Supplement 1): 842.
https://doi.org/10.1182/blood-2024-212313
Published: 2024
Journal Articles

Newly Developed Prognostic Score for Myelodysplastic Syndrome (MDS) with Isolated 5q Deletion (IPSS-del(5q))

Free
Maria Julia Montoro, Laura Palomo, Claudia Haferlach, Pamela Acha, Onyee Chan, Víctor Navarro, Yasuo Kubota, Felicitas Schulz, Robert Briski, Najla H Al Ali, Blanca Xicoy, Felix Lopez, Francesc Bosch, Manja Meggendorfer, Teresa González, Lea Naomi Eder, Andres Jerez, Yu-Hung Wang, Alessia Campagna, Valeria Santini, Teresa Bernal, Esperanza Such, Hwei-Fang Tien, Anne Sophie Kubasch, Nicolas Díaz Varela, Uwe Platzbecker, Detlef Haase, Maria Diez-Campelo, Matteo Giovanni Della Porta, Guillermo Garcia-Manero, Daniel H Wiseman, Ulrich Germing, Jaroslaw Maciejewski, Rami S. Komrokji, Francesc Sole, Torsten Haferlach, David Valcarcel
Journal: Blood
Blood (2024) 144 (Supplement 1): 666.
https://doi.org/10.1182/blood-2024-194405
Published: 2024
Journal Articles

Impact of Response to Hypomethylating Agent-Based Therapy on Survival Outcomes in the Context of Baseline Clinical-Molecular Risk and Transplant Status in Patients with Myelodysplastic Syndromes/Neoplasms (MDS): An Analysis from the International Consortium for MDS (icMDS) Validate Database

Free
Benjamin Rolles, Jan Philipp Bewersdorf, Tariq Kewan, Ondrej Blaha, Jessica M. Stempel, Luca Lanino, Najla H. Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Geoffrey L. Uy, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Christine M. McMahon, Rory M. Shallis, Joshua F Zeidner, Michael R. Savona, Stacey M. Frumm, Shougat Barua, Namrata S. Chandhok, Constantine Logothetis, Aram Bidikian, Ted M. Getz, Gail J. Roboz, Eunice S. Wang, Amyah C. Harris, Maria L Amaya, Hayley Hawkins, Somedeb Ball, Justin Grenet, Zhuoer Xie, Yazan F Madanat, Yasmin Abaza, Talha Badar, Torsten Haferlach, Jaroslaw Maciejewski, David Sallman, Anoop K Enjeti, Kamal Al-Rabi, Khalid Halahleh, Devendra Hiwase, Maria Diez-Campelo, David Valcarcel, Claudia Haferlach, Lisa Pleyer, Ioannis Kotsianidis, Vassiliki Pappa, Valeria Santini, Angela Consagra, Aref Al-Kali, Seishi Ogawa, Yasuhito Nannya, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan, Maximilian Stahl
Journal: Blood
Blood (2024) 144 (Supplement 1): 664.
https://doi.org/10.1182/blood-2024-208034
Published: 2024
Journal Articles

Genetic Determinants of Hypercoagulability in Complement and Hemostatic Systems Shape the Thrombotic Risk of Paroxysmal Nocturnal Hemoglobinuria

Free
Carlos Bravo-Perez, Carmelo Gurnari, Arda Durmaz, Stephan Hutter, Zachary Brady, Hussein Awada, Aashray Mandala, Luca Guarnera, Matteo D'Addona, Kartik Lakhotiya, Praveena Thiagarajan, Alan Eli Lichtin, Torsten Haferlach, Valeria Visconte, Jaroslaw Maciejewski
Journal: Blood
Blood (2024) 144 (Supplement 1): 31.
https://doi.org/10.1182/blood-2024-208885
Published: 2024
Journal Articles

First Results of High Throughput Pipeline for Serotypic and TCR Clonotypic Specificities in Aplastic Anemia and Large Granular Lymphocyte Leukemia Uncovering Antigenic Peptides Relevant to Disease Etiology

Free
Kartik Lakhotiya, Carmelo Gurnari, Carlos Bravo-Perez, Aashray Mandala, Matteo D'Addona, Christopher Haddad, Mark Orland, Zachary Brady, Luca Guarnera, Praveena Thiagarajan, Ishani Nautiyal, Simona Pagliuca, Hari Krishnamurthy, Karthik Krishna, Vasanth Jayaraman, Valeria Visconte, Jaroslaw Maciejewski, Arda Durmaz
Journal: Blood
Blood (2024) 144 (Supplement 1): 35.
https://doi.org/10.1182/blood-2024-210990
Published: 2024
Journal Articles

Clinical Outcomes and Variability Based on Baseline Cytogenetic Risk of Patients with MDS Treated with Hypomethylating Agents: An Analysis from the International Consortium for MDS (icMDS) Validate Database

Free
Ted M. Getz, Tariq Kewan, Jan Philipp Bewersdorf, Jessica M. Stempel, Luca Lanino, Wei Wei, Najla H. Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Geoffrey L. Uy, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Christine M. McMahon, Rory M. Shallis, Joshua F Zeidner, Michael R. Savona, Somedeb Ball, Namrata S. Chandhok, Constantine Logothetis, Aram Bidikian, Gail J. Roboz, Benjamin Rolles, Eunice S. Wang, Amyah C. Harris, Maria L Amaya, Hayley Hawkins, Justin Grenet, Zhuoer Xie, Yazan F. Madanat, Yasmin Abaza, Talha Badar, Torsten Haferlach, Jaroslaw Maciejewski, David Sallman, Anoop K Enjeti, Kamal Al-Rabi, Khalid Halahleh, Devendra Hiwase, Maria Diez-Campelo, David Valcarcel, Claudia Haferlach, Lisa Pleyer, Ioannis Kotsianidis, Vasiliki Pappa, Valeria Santini, Angela Consagra, Aref Al-Kali, Seishi Ogawa, Yasuhito Nannya, Maximilian Stahl, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan
Journal: Blood
Blood (2024) 144 (Supplement 1): 3219.
https://doi.org/10.1182/blood-2024-202075
Published: 2024
Journal Articles

Incorporating TET2 Variant Allele Frequency Enhances Prognostication in CMML: Insights from 849 Patients across Multiple Institutions

Free
Yu-Hung Wang, Dorothée Selimoglu-Buet, Carmelo Gurnari, Andres Jerez, Andrius Zucenka, Chi-Yuan Yao, Chien-Chin Lin, Hsin-An Hou, Wen-Chien Chou, Hwei-Fang Tien, Jaroslaw Maciejewski, Eric Solary, Kiran Batta, Daniel H Wiseman
Journal: Blood
Blood (2024) 144 (Supplement 1): 4579.
https://doi.org/10.1182/blood-2024-194319
Published: 2024
Journal Articles

Elucidating the Somatic Genetic Rescue Underlying Del(20q) Myeloid Neoplasms

Free
Mark Orland, Arda Durmaz, Carlos Bravo-Perez, Carmelo Gurnari, Luca Guarnera, Matteo D'Addona, Aashray Mandala, Christopher Haddad, Kartik Lakhotiya, Valeria Visconte, Jaroslaw Maciejewski
Journal: Blood
Blood (2024) 144 (Supplement 1): 4573.
https://doi.org/10.1182/blood-2024-208520
Published: 2024
Journal Articles

Distinct Phenotypes of Myeloid Neoplasia Associated with Truncating C-CBL Mutations

Free
Luca Guarnera, Carmelo Gurnari, Carlos Bravo-Perez, Arda Durmaz, Nakisha D Williams, Hussein Awada, Matteo D'Addona, Naomi Kawashima, Arooj Ahmed, Serhan Unlu, Olisaemeka Ogbue, Christopher Haddad, Aashray Mandala, Yasuo Kubota, Juraj Bodo, Genevieve M Crane, Heesun J. Rogers, Jaroslaw Maciejewski, Valeria Visconte
Journal: Blood
Blood (2024) 144 (Supplement 1): 2920.
https://doi.org/10.1182/blood-2024-209834
Published: 2024
Journal Articles

Developing a Therapeutic Strategy for Targeting Metabolic Vulnerability of TET2 Mutant Leukemia

Free
Xiaorong Gu, Yahan Zhang, Songa Bae, Dongxu Jiang, Nakisha D Williams, Daniel Vail, Simon Schlanger, Jill Durkin, Yvonne Parker, Daniel Lindner, Jaroslaw Maciejewski, Babal K. Jha
Journal: Blood
Blood (2024) 144 (Supplement 1): 2918.
https://doi.org/10.1182/blood-2024-207470
Published: 2024
Journal Articles

A Dedicated System Accounting for Specific Germline/Somatic Genomic Constellations Is Essential to Predict Outcomes in DDX41 -Mutant Myeloid Neoplasia

Free
Carmelo Gurnari, Hideki Makishima, Arda Durmaz, Enrico Attardi, Ryunosuke Saiki, Alex Bataller, Guilherme Mendes Sapinho, Lukasz P. Gondek, Yasuhito Nannya, Steve Best, Pramila Krishnamurthy, Kar Lok Kong, Yoshiko Atsuta, Senji Kasahara, Kazuma Ohyashiki, Yasushi Miyazaki, Nobuhiro Kanemura, Nobuhiro Hiramoto, Hussein Awada, Valeria Visconte, Courtney D. DiNardo, Maria Teresa Voso, Amy E. DeZern, Guillermo Garcia-Manero, Austin G. Kulasekararaj, Jaroslaw Maciejewski, Seishi Ogawa
Journal: Blood
Blood (2024) 144 (Supplement 1): 1332.
https://doi.org/10.1182/blood-2024-194024
Published: 2024
Journal Articles

Genomic Landscape of Germline RUNX1 variants in Adult Myeloid Neoplasia According to Functional Impact

Free
Christopher Haddad, Luca Guarnera, Yasuo Kubota, Carlos Bravo-Perez, Carmelo Gurnari, Olisaemeka Ogbue, Arda Durmaz, Serhan Unlu, Aashray Mandala, Mark Orland, Zachary Brady, Kartik Lakhotiya, Matteo D'Addona, Ishani Nautiyal, David S. Bosler, Hetty E. Carraway, Yogen Saunthararajah, Valeria Visconte, Jaroslaw Maciejewski
Journal: Blood
Blood (2024) 144 (Supplement 1): 1328.
https://doi.org/10.1182/blood-2024-210419
Published: 2024
Journal Articles

Budd-Chiari Syndrome: Pathogenetic Factors and Completeness of Screening for Paroxysmal Nocturnal Hemoglobinuria

Free
Aashray Mandala, Carlos Bravo-Perez, Zachary Brady, Matteo D'Addona, Arda Durmaz, Mark Orland, Kartik Lakhotiya, Christopher Haddad, Praveena Thiagarajan, Valeria Visconte, Carmelo Gurnari, Jaroslaw Maciejewski
Journal: Blood
Blood (2024) 144 (Supplement 1): 1254.
https://doi.org/10.1182/blood-2024-211609
Published: 2024
Journal Articles

Using Machine Learning to Predict the Risk of Evolution to Paroxysmal Nocturnal Hemoglobinuria in Patients with Aplastic Anemia

Free
Erika Ren, Katayoun Elizabeth Khalilian, Mutlu Mete, Carmelo Gurnari, Jaroslaw Maciejewski, Carlos Bravo-Perez, Taha Bat
Journal: Blood
Blood (2024) 144 (Supplement 1): 1315.
https://doi.org/10.1182/blood-2024-203826
Published: 2024
Journal Articles

Prediction of Post-Transplant Relapse of the Myelodysplastic Syndromes Via Evaluation of Stem Cells

Free
Benjamin Kroger, Roni Tamari, Carmelo Gurnari, Julio Alvarenga Thiebaud, Alejandro Marinos Velarde, Yazan F Madanat, Robert H. Collins, Clayton Jackson, Vivian Irizarry Gatell, Valeria Visconte, Jaroslaw Maciejewski, David Sallman, Stephen Chung
Journal: Blood
Blood (2024) 144 (Supplement 1): 777.
https://doi.org/10.1182/blood-2024-212380
Published: 2024
Journal Articles

Bi-Allelic DDX41 Mutations Exert Stage Specific Effects on Hematopoiesis to Promote Disease

Free
Benjamin Kroger, Yuanyuan Ji, Toby Thomas, Yazan F Madanat, Robert H. Collins, Valeria Visconte, Carmelo Gurnari, Jaroslaw Maciejewski, Stephen Chung
Journal: Blood
Blood (2024) 144 (Supplement 1): 347.
https://doi.org/10.1182/blood-2024-209425
Published: 2024
Journal Articles

Age-Related Cellular Factors Facilitate TET2 Mutant Clonal Hematopoiesis

Free
Daniel J Vail, Dongxu Jiang, Kunho Chung, Yahan Zhang, Sophia Martinez, Luca Guarnera, Yvonne Parker, J. Joseph Melenhorst, Daniel Lindner, Jaroslaw Maciejewski, Babal K. Jha
Journal: Blood
Blood (2024) 144 (Supplement 1): 1278.
https://doi.org/10.1182/blood-2024-211683
Published: 2024
Journal Articles

Identification of Tumor Suppressors and Synthetic Lethal Targets in -7/del7q Myeloid Neoplasms By Iterative Computational Analysis Coupled with Experimental Validation

Free
Daniel J Vail, Valeria Visconte, Babal K. Jha, Jill Durkin, Jaroslaw Maciejewski, Thomas Laframboise
Journal: Blood
Blood (2024) 144 (Supplement 1): 4303.
https://doi.org/10.1182/blood-2024-210881
Published: 2024