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Journal Articles

Molecular taxonomy of myelodysplastic syndromes and its clinical implications

Elsa Bernard, Robert P. Hasserjian, Peter L. Greenberg, Juan E. Arango Ossa, Maria Creignou, Heinz Tuechler, Jesus Gutierrez-Abril, Dylan Domenico, Juan S. Medina-Martinez, Max Levine, Konstantinos Liosis, Noushin Farnoud, Maria Sirenko, Martin Jädersten, Ulrich Germing, Guillermo Sanz, Arjan A. van de Loosdrecht, Yasuhito Nannya, Olivier Kosmider, Matilde Y. Follo, Felicitas Thol, Lurdes Zamora, Ronald F. Pinheiro, Andrea Pellagatti, Harold K. Elias, Detlef Haase, Christina Ganster, Lionel Ades, Magnus Tobiasson, Laura Palomo, Matteo Giovanni Della Porta, Pierre Fenaux, Monika Belickova, Michael R. Savona, Virginia M. Klimek, Fabio P. S. Santos, Jacqueline Boultwood, Ioannis Kotsianidis, Valeria Santini, Francesc Solé, Uwe Platzbecker, Michael Heuser, Peter Valent, Carlo Finelli, Maria Teresa Voso, Lee-Yung Shih, Michaela Fontenay, Joop H. Jansen, José Cervera, Norbert Gattermann, Benjamin L. Ebert, Rafael Bejar, Luca Malcovati, Seishi Ogawa, Mario Cazzola, Eva Hellström-Lindberg, Elli Papaemmanuil

Blood (2024) 144 (15): 1617–1632.

https://doi.org/10.1182/blood.2023023727

Published: 2024

Includes: Supplemental data

Journal Articles

Molecular and clinical presentation of UBA1 -mutated myelodysplastic syndromes

Maria Sirenko, Elsa Bernard, Maria Creignou, Dylan Domenico, Andrea Farina, Juan E. Arango Ossa, Olivier Kosmider, Robert Hasserjian, Martin Jädersten, Ulrich Germing, Guillermo Sanz, Arjan A. van de Loosdrecht, Carmelo Gurnari, Matilde Yung Follo, Felicitas Thol, Lurdes Zamora, Ronald Feitosa Pinheiro, Andrea Pellagatti, Harold K. Elias, Detlef Haase, Birgitta Sander, Elisa Orna, Katharina Zoldan, Lea Naomi Eder, Wolfgang R. Sperr, Renate Thalhammer, Christina Ganster, Lionel Adès, Magnus Tobiasson, Laura Palomo, Matteo Giovanni Della Porta, Kety Huberman, Pierre Fenaux, Monika Belickova, Michael R. Savona, Virginia M. Klimek, Fabio P. S. Santos, Jacqueline Boultwood, Ioannis Kotsianidis, Valeria Santini, Francesc Solé, Uwe Platzbecker, Michael Heuser, Peter Valent, Carlo Finelli, Maria Teresa Voso, Lee-Yung Shih, Seishi Ogawa, Michaela Fontenay, Joop H. Jansen, Jose Cervera, Benjamin L. Ebert, Rafael Bejar, Peter L. Greenberg, Norbert Gattermann, Luca Malcovati, Mario Cazzola, David B. Beck, Eva Hellström-Lindberg, Elli Papaemmanuil

Blood (2024) 144 (11): 1221–1229.

https://doi.org/10.1182/blood.2023023723

Published: 2024

Includes: Supplemental data

Journal Articles

Malignancy-associated hemophagocytic lymphohistiocytosis in Sweden: incidence, clinical characteristics, and survival

Alexandra Löfstedt, Martin Jädersten, Marie Meeths, Jan-Inge Henter

Blood (2024) 143 (3): 233–242.

https://doi.org/10.1182/blood.2023020715

Published: 2024

Includes: Supplemental data

Journal Articles

Molecular Taxonomy of Myelodysplastic Syndromes and Its Clinical Implications

Elsa Bernard, Robert Hasserjian, Peter L. Greenberg, Juan E Arango Ossa, Maria Creignou, Yasuhito Nannya, Heinz Tuechler, Juan S Medina-Martínez, Max F Levine, Martin Jädersten, Ulrich Germing, Guillermo Sanz, Arjan A. van de Loosdrecht, Olivier Kosmider, Matilde Yung Follo, Felicitas Thol, Lurdes Zamora, Ronald Feitosa Pinheiro, Andrea Pellagatti, Harold K Elias, Detlef Haase, Maria Sirenko, Christina Ganster, Lionel Ades, Magnus Tobiasson, Laura Palomo, Matteo Giovanni Della Porta, Pierre Fenaux, Monika Belickova, Michael R. Savona, Virginia M. Klimek, Fabio P. S. Santos, Jacqueline Boultwood, Ioannis Kotsianidis, Valeria Santini, Francesc Sole, Uwe Platzbecker, Michael Heuser, Peter Valent, Carlo Finelli, Maria Teresa Voso, Lee-Yung Shih, Michaela Fontenay, Joop H. Jansen, Jose Cervera, Norbert Gattermann, Benjamin L. Ebert, Rafael Bejar, Luca Malcovati, Mario Cazzola, Seishi Ogawa, Eva Hellstrom Lindberg, Elli Papaemmanuil

Blood (2023) 142 (Supplement 1): 997.

https://doi.org/10.1182/blood-2023-186863

Published: 2023

Journal Articles

UBA1 Mutations Identify a Rare but Distinct Subtype of Myelodysplastic Syndromes

Maria Sirenko, Elsa Bernard, Maria Creignou, Dylan Domenico, Andrea Farina, Juan E Arango Ossa, Olivier Kosmider, Robert Hasserjian, Martin Jädersten, Ulrich Germing, Guillermo Sanz, Arjan A. van de Loosdrecht, Carmelo Gurnari, Matilde Yung Follo, Felicitas Thol, Lurdes Zamora, Andrea Pellagatti, Harold K Elias, Detlef Haase, Christina Ganster, Lionel Ades, Magnus Tobiasson, Laura Palomo, Matteo Giovanni Della Porta, Kety Huberman, Pierre Fenaux, Monika Belickova, Michael R. Savona, Virginia M. Klimek, Fabio P. S. Santos, Jacqueline Boultwood, Ioannis Kotsianidis, Valeria Santini, Francesc Sole, Uwe Platzbecker, Michael Heuser, Peter Valent, Carlo Finelli, Maria Teresa Voso, Lee-Yung Shih, Seishi Ogawa, Michaela Fontenay, Joop H. Jansen, Jose Cervera, Benjamin L. Ebert, Rafael Bejar, Peter L. Greenberg, Norbert Gattermann, Luca Malcovati, Mario Cazzola, David B Beck, Eva Hellstrom Lindberg, Elli Papaemmanuil

Blood (2023) 142 (Supplement 1): 1862.

https://doi.org/10.1182/blood-2023-182949

Published: 2023

Journal Articles

Characterization of the bone marrow niche in patients with chronic myeloid leukemia identifies CXCL14 as a new therapeutic option

Blood (2023) 142 (1): 73–89.

https://doi.org/10.1182/blood.2022016896

Published: 2023

Includes: Supplemental data

Journal Articles

Transfusion Patterns during Early Follow-up Predict Overall Survival Independently of IPSS-M in Patients with Myelodysplastic Syndromes

Maria Creignou, Elsa Bernard, Michael Crowther, Anna Tranberg, Elisabeth Ejerblad, Lars Nilsson, Hege Garelius, Petar Antunovic, Bengt Erik Holger Rasmussen, Fryderyk Lorenz, Gabriele Todisco, Gunilla Walldin, Teresa Mortera-Blanco, Monika Jansson, Magnus Tobiasson, Gustaf Edgren, Martin Jadersten, Elli Papaemmanuil, Eva Hellström-Lindberg

Blood (2022) 140 (Supplement 1): 6968–6970.

https://doi.org/10.1182/blood-2022-155811

Published: 2022

Journal Articles

Incidence, Clinical Associations, and Co-Mutation Patterns of UBA1 Mutations in MDS

Maria Sirenko, Elsa Bernard, David B. Beck, Maria Creignou, Dylan Domenico, Andrea Farina, Juan E Arango, Olivier Kosmider, Robert P. Hasserjian, Martin Jadersten, Ulrich Germing, Guillermo Sanz, Arjan A. van de Loosdrecht, Matilde Y Follo, Felicitas R. Thol, Lurdes Zamora, Ronald Feitosa Pinheiro, Andrea Pellagatti, Harold K. Elias, Detlef Haase, Christina Ganster, Lionel Ades, Magnus Tobiasson, Laura Palomo, Matteo G. Della Porta, Kety Huberman, Pierre Fenaux, Monika Belickova, Michael R. Savona, Virginia M. Klimek, Fabio Pires de Souza Santos, Jacqueline Boultwood, Ioannis Kotsianidis, Valeria Santini, Francesc Solé, Uwe Platzbecker, Michael Heuser, Peter Valent, Carlo Finelli, Maria Teresa Voso, Lee-Yung Shih, Seishi Ogawa, Michaela Fontenay, Joop H. Jansen, Jose Cervera, Benjamin L. Ebert, Rafael Bejar, Peter L Greenberg, Norbert Gattermann, Luca Malcovati, Mario Cazzola, Eva Hellström-Lindberg, Elli Papaemmanuil

Blood (2022) 140 (Supplement 1): 9785–9788.

https://doi.org/10.1182/blood-2022-162397

Published: 2022

Journal Articles

TP53 State Dictates Genome Stability, Clinical Presentation and Outcomes in Myelodysplastic Syndromes

Elsa Bernard, PhD, Yasuhito Nannya, MD PhD, Tetsuichi Yoshizato, MD PhD, Robert P. Hasserjian, MD, Ryunosuke Saiki, Yusuke Shiozawa, MD PhD, Sean M. Devlin, PhD, Heinz Tuechler, Araxe Sarian, Luca Malcovati, MD, Francesc Sole, PhD, Detlef Haase, MD, Maria Creignou, Max Levine, MS, Ulrich Germing, MD, Catherine Cargo, MB, FRCPath, Yanming Zhang, MD, Juan Medina, MS, Juan E. Arango Ossa, BS, Julie Schanz, MD PhD, Arjan van de Loosdrecht, MD PhD, Martin Jädersten, MD PhD, John M. Bennett, MD, Magnus Tobiasson, MD PhD, Olivier Kosmider, PharmD, PhD, Matilde Y Follo, PhD, Felicitas Thol, MD, Ronald F Pinheiro, MD, Valeria Santini, MD, Ioannis Kotsianidis, Jacqueline Boultwood, Fabio PS Santos, MD, Senji Kasahara, MD PhD, Takayuki Ishikawa, MD PhD, Hisashi Tsurumi, MD PhD, Akifumi Takaori-Kondo, MD PhD, Toru Kiguchi, Chantana Polprasert, MD, Virginia M. Klimek, MD, Michael R. Savona, MD, Monika Belickova, PhD, Christina Ganster, Lionel Ades, MD PhD, Matteo Giovanni Della Porta, MD, Alexandra Smith, PhD, Yesenia Werner, Minal A Patel, MPH, Agnes Viale, PhD, Katelynd Vanness, Donna S Neuberg, ScD, Kristen E. Stevenson, MS, Kamal Menghrajani, MD, Kelly Bolton, MD PhD, Pierre Fenaux, MD PhD, Andrea Pellagatti, Uwe Platzbecker, MD, Michael Heuser, MD, Peter Valent, MD, Shigeru Chiba, MD PhD, Yasushi Miyazaki, MD PhD, Carlo Finelli, Maria Teresa Voso, MD, Lee-Yung Shih, MD, Michaela Fontenay, MD PhD, Joop H. Jansen, PhD, José Cervera, MD PhD, Yoshiko Atsuta, MD PhD, Norbert Gattermann, MD, Benjamin L. Ebert, MD PhD, Rafael Bejar, MD PhD, Peter L Greenberg, MD, Mario Cazzola, MD, Eva Hellstrom Lindberg, MD PhD, Seishi Ogawa, MD PhD, Elli Papaemmanuil, PhD

Blood (2019) 134 (Supplement_1): 675.

https://doi.org/10.1182/blood-2019-129392

Published: 2019

Journal Articles

Improved survival of men 50 to 75 years old with acute myeloid leukemia over a 20-year period

Gunnar Juliusson, Oskar Hagberg, Vladimir Lj Lazarevic, Emma Ölander, Petar Antunovic, Jörg Cammenga, Lovisa Wennström, Lars Möllgård, Mats Brune, Martin Jädersten, Stefan Deneberg, Sören Lehmann, Åsa Rangert Derolf, Martin Höglund

Blood (2019) 134 (18): 1558–1561.

https://doi.org/10.1182/blood.2019001728

Published: 2019

Includes: Supplemental data

Journal Articles

Resistance to Lenalidomide in Del(5q) MDS Is Mediated By Inhibition of Drug-Induced Megakaryocytic Differentiation

Sergio Martinez-Høyer, PhD, Angela Mo, Deborah Deng, Jihong Jiang, Rod Docking, MSc, Jenny Li, Simon Chan, Patricia Umlandt, Megan Fuller, Martin Jädersten, Eva Hellström-Lindberg, MD PhD, Uwe Platzbecker, Jeremy Parker, PhD, Aly Karsan, MD

Blood (2018) 132 (Supplement 1): 176.

https://doi.org/10.1182/blood-2018-176

Published: 2018

Journal Articles

Progression in Patients with with Low- and Intermediate-1 Risk Del(5q) MDS Is Predicted By a Limited Subset of Mutations

Christian Scharenberg, MD, Petter S. Woll, PhD, Valentina Giai, MD PhD, Andrea Pellagatti, PhD, Leonie Saft, MD PhD, Marios Dimitriou, Martin Jädersten, Monika Jansson, Iyadh Douagi, PhD, Donna S. Neuberg, ScD, Mohsen Karimi, Katarina Le Blanc, MD, PhD, Jacqueline Boultwood, PhD, Sten Eirik Jacobsen, MD PhD, Eva Hellstrom-Lindberg, MD PhD

Blood (2016) 128 (22): 4329.

https://doi.org/10.1182/blood.V128.22.4329.4329

Published: 2016

Journal Articles

Mechanisms of Resistance to Lenalidomide in Del(5q) Myelodysplastic Syndrome Patients

Sergio Martinez-Høyer, PhD, Rod Docking, PhD, Simon Chan, Martin Jadersten, MDPhD, Jeremy Parker, PhD, Aly Karsan, MD

Blood (2015) 126 (23): 5228.

https://doi.org/10.1182/blood.V126.23.5228.5228

Published: 2015

Journal Articles

Mutations in Histone Modulators Are Associated with Prolonged Survival during Azacitidine Therapy

Magnus Tobiasson, MD, Donal McLornan, MDPhD, Mohsen Karimi, Marios Dimitriou, PhD, Monika Jansson, Asmaa Ben Azenkoud, Martin Jädersten, Greger Lindberg, Hani Abdulkadir, Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath, Johanna Ungerstedt, Associate Professor, Andreas Lennartsson, Karl Ekwall, Ghulam J Mufti, Eva Hellström-Lindberg, MD PhD

Blood (2015) 126 (23): 2839.

https://doi.org/10.1182/blood.V126.23.2839.2839

Published: 2015

Journal Articles

SF3B1 mutation identifies a distinct subset of myelodysplastic syndrome with ring sideroblasts

Blood (2015) 126 (2): 233–241.

https://doi.org/10.1182/blood-2015-03-633537

Published: 2015

Includes: Supplemental data

Journal Articles

Genetic Determinants of Disease Phenotype and Clinical Outcome in Myelodysplastic Syndromes with Ring Sideroblasts

Blood (2014) 124 (21): 825.

https://doi.org/10.1182/blood.V124.21.825.825

Published: 2014

Journal Articles

Mutations in Histone Modulators and HOXA5 Methylation Levels Affects Survival in Azacitidine Treated MDS Patients

Magnus Tobiasson, MD, Mohsen Karimi, Marios Dimitriou, Ying Qu, MDM.Sc, Andreas Lennartsson, PhD, Hani Abdulkadir Ali, Ashwin Unnikrishnan, PhD, Martin Jadersten, MDPhD, Monika Jansson, Asmaa Ben Azenkoud, John E Pimanda, MD PhD, Karl Ekwall, Prof, Johanna Ungerstedt, MD PhD, Soren Lehmann, MD PhD, Eva Hellstrom-Lindberg, MD PhD

Blood (2014) 124 (21): 4613.

https://doi.org/10.1182/blood.V124.21.4613.4613

Published: 2014

Journal Articles

Association Between Gene Expression Profiles and Commonly Mutated Genes In The Hematopoietic Stem Cells Of Patients With Myelodysplastic Syndromes

Andrea Pellagatti, PhD, Moritz Gerstung, PhD, Elli Papaemmanuil, PhD, Luca Malcovati, MD, Aristoteles Giagounidis, MD, PhD, Matteo G Della Porta, MD, Martin Jadersten, MD, PhD, Amit Verma, MD, Paresh Vyas, MD, PhD, Sally Killick, MD, Eva Hellstrom-Lindberg, MD, Mario Cazzola, MD, Peter J. Campbell, PhD, Jacqueline Boultwood

Blood (2013) 122 (21): 2779.

https://doi.org/10.1182/blood.V122.21.2779.2779

Published: 2013

Journal Articles

Identification of Gene Expression Based Prognostic Markers in the Hematopoietic Stem Cells of Patients with Myelodysplastic Syndromes

Andrea Pellagatti, Axel Benner, Dipl.Stat., Ken I Mills, PhD, Mario Cazzola, Aristoteles Giagounidis, MD, Janet Perry, Luca Malcovati, Matteo G Della Porta, Martin Jadersten, Amit Verma, Emma-Jane McDonald, Sally Killick, Eva Hellstrom-Lindberg, Lars Bullinger, MD, PhD, James S Wainscoat, Jacqueline Boultwood, MD

Blood (2012) 120 (21): 3857.

https://doi.org/10.1182/blood.V120.21.3857.3857

Published: 2012

Journal Articles

Del(5q) Myelodysplastic Stem Cells Exhibit Their Clonal Advantage Via Increased Adhesion to the Microenvironment

Christian Scharenberg, MD, Valentina Giai, MD, Andrea Pellagatti, PhD, Leonie Saft, MD, Goran Karlsson, PhD, Monika Jansson, Lalla Forsblom, Martin Jadersten, MD, PhD, Stefan Karlsson, M.D., Ph.D., Prof., Jacqueline Boultwood, PhD, Eva Hellstrom-Lindberg, MD, PhD

Blood (2011) 118 (21): 790.

https://doi.org/10.1182/blood.V118.21.790.790

Published: 2011

NARROW

Molecular taxonomy of myelodysplastic syndromes and its clinical implications

Molecular and clinical presentation of UBA1 -mutated myelodysplastic syndromes

Malignancy-associated hemophagocytic lymphohistiocytosis in Sweden: incidence, clinical characteristics, and survival

Molecular Taxonomy of Myelodysplastic Syndromes and Its Clinical Implications

UBA1 Mutations Identify a Rare but Distinct Subtype of Myelodysplastic Syndromes

Characterization of the bone marrow niche in patients with chronic myeloid leukemia identifies CXCL14 as a new therapeutic option

Transfusion Patterns during Early Follow-up Predict Overall Survival Independently of IPSS-M in Patients with Myelodysplastic Syndromes

Incidence, Clinical Associations, and Co-Mutation Patterns of UBA1 Mutations in MDS

TP53 State Dictates Genome Stability, Clinical Presentation and Outcomes in Myelodysplastic Syndromes

Improved survival of men 50 to 75 years old with acute myeloid leukemia over a 20-year period

Resistance to Lenalidomide in Del(5q) MDS Is Mediated By Inhibition of Drug-Induced Megakaryocytic Differentiation

Progression in Patients with with Low- and Intermediate-1 Risk Del(5q) MDS Is Predicted By a Limited Subset of Mutations

Mechanisms of Resistance to Lenalidomide in Del(5q) Myelodysplastic Syndrome Patients

Mutations in Histone Modulators Are Associated with Prolonged Survival during Azacitidine Therapy

SF3B1 mutation identifies a distinct subset of myelodysplastic syndrome with ring sideroblasts

Genetic Determinants of Disease Phenotype and Clinical Outcome in Myelodysplastic Syndromes with Ring Sideroblasts

Mutations in Histone Modulators and HOXA5 Methylation Levels Affects Survival in Azacitidine Treated MDS Patients

Association Between Gene Expression Profiles and Commonly Mutated Genes In The Hematopoietic Stem Cells Of Patients With Myelodysplastic Syndromes

Identification of Gene Expression Based Prognostic Markers in the Hematopoietic Stem Cells of Patients with Myelodysplastic Syndromes

Del(5q) Myelodysplastic Stem Cells Exhibit Their Clonal Advantage Via Increased Adhesion to the Microenvironment

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