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Ulrich Duhrsen
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Journal Articles

Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy

Daria Frank, Pradeep Kumar Patnana, Jan Vorwerk, Lianghao Mao, Lavanya Mokada Gopal, Noelle Jung, Thorben Hennig, Leo Ruhnke, Joris Maximillian Frenz, Maithreyan Kuppusamy, Robert Autry, Lanying Wei, Kaiyan Sun, Helal Mohammed Mohammed Ahmed, Axel Künstner, Hauke Busch, Heiko Müller, Stephan Hutter, Gregor Hoermann, Longlong Liu, Xiaoqing Xie, Yahya Al-Matary, Subbaiah Chary Nimmagadda, Fiorella Charles Cano, Michael Heuser, Felicitas Thol, Gudrun Göhring, Doris Steinemann, Jürgen Thomale, Theo Leitner, Anja Fischer, Roland Rad, Christoph Röllig, Heidi Altmann, Desiree Kunadt, Wolfgang E. Berdel, Jana Hüve, Felix Neumann, Jürgen Klingauf, Virginie Calderon, Bertram Opalka, Ulrich Dührsen, Frank Rosenbauer, Martin Dugas, Julian Varghese, Hans Christian Reinhardt, Nikolas von Bubnoff, Tarik Möröy, Georg Lenz, Aarif M. N. Batcha, Marianna Giorgi, Murugan Selvam, Eunice Wang, Shannon K. McWeeney, Jeffrey W. Tyner, Friedrich Stölzel, Matthias Mann, Ashok Kumar Jayavelu, Cyrus Khandanpour
Journal: Blood
Blood (2023) 142 (25): 2175–2191.
https://doi.org/10.1182/blood.2022015752
Published: 2023
Includes: Supplemental data
Journal Articles

Determinants of Resistance to Engineered T-Cell Therapies Targeting CD19 in Large B-Cell Lymphomas

Brian Sworder, David M. Kurtz, Stefan K. Alig, Matthew J Frank, Navika D. Shukla, Andrea Garofalo, Charles Macaulay, Mohammad Shahrokh Esfahani, Mari Olsen, James Hamilton, III, Hitomi Hosoya, Mark P Hamilton, Jay Y. Spiegel, John H. Baird, Mia Carleton, Alexander F.M. Craig, Sheren F. Younes, Bita Sahaf, Natasha Sheybani, Joseph Schroers-Martin, Chih Long Liu, Jean S Oak, Michael C. Jin, Sara Beygi, Andreas Hüttmann, Christine Hanoun, Ulrich Dührsen, Jason Westin, Michael S. Khodadoust, Yasodha Natkunam, Robbie G. Majzner, Crystal L. Mackall, Maximilian Diehn, David B. Miklos, Ash A. Alizadeh
Journal: Blood
Blood (2022) 140 (Supplement 1): 1301–1303.
https://doi.org/10.1182/blood-2022-165545
Published: 2022
Journal Articles

External Validation Shows That Baseline PET Radiomics Outperform the IPI Risk Score for Prediction of Outcome in DLBCL

Jakoba J Eertink, Gerben JC Zwezerijnen, Martijn W Heymans, Simone Pieplenbosch, Sanne E Wiegers, Ulrich Dührsen, Andreas Hüttmann, Lars Kurch, Christine Hanoun, Pieternella Lugtenburg, Sally F Barrington, George Mikhaeel, Luca Ceriani, Emanuele Zucca, Sandor Czibor, Tamás Györke, Martine E.D. Chamuleau, Otto S Hoekstra, Henrica C.W de Vet, Ronald Boellaard, Josée M. Zijlstra
Journal: Blood
Blood (2022) 140 (Supplement 1): 777–778.
https://doi.org/10.1182/blood-2022-163454
Published: 2022
Journal Articles

The Position of MYC Rearrangements in the Genomic Landscape of Diffuse Large B-Cell Lymphoma

Erik Van Dijk, Jurriaan Janssen, Matias Mendeville, G. Tjitske Los-De Vries, Margaretha GM Roemer, Phylicia Stathi, Julia Richter, Yong Soo Kim, Wolfram Klapper, Ulrich Dührsen, Andreas Hüttmann, P. J Lugtenburg, Josée M. Zijlstra, Marie Jose Kersten, Daphne de Jong, Martine E.D. Chamuleau, Bauke Ylstra
Journal: Blood
Blood (2022) 140 (Supplement 1): 9261–9263.
https://doi.org/10.1182/blood-2022-160052
Published: 2022
Journal Articles

Modified Risk-Stratified Sequential Treatment in B-Cell Post-Transplant Lymphoproliferative Disorder (PTLD) after Solid Organ Transplantation (SOT): The Prospective Multicenter Phase II PTLD-2 Trial

Heiner Zimmermann, Christian Koenecke, Martin H. Dreyling, Christiane Pott, Ulrich Dührsen, Dennis Hahn, Norbert Meidenbauer, Ingeborg A Hauser, Mathias J. Rummel, Dominik Wolf, Michael Heuser, Christian Schmidt, Peter Schlattmann, Matthias Ritgen, Reiner Siebert, Ilske Oschlies, Ioannis Anagnostopoulos, Ralf Ulrich Trappe
Journal: Blood
Blood (2021) 138 (Supplement 1): 3555.
https://doi.org/10.1182/blood-2021-146823
Published: 2021
Journal Articles

Combining PET Radiomic Features with MYC Gene Rearrangement Results in High Prediction of Outcome in Diffuse Large B-Cell Lymphoma

Jakoba J Eertink, Gerben J.C Zwezerijnen, Sanne E Wiegers, Martine E.D Chamuleau, Pieternella Lugtenburg, Daphne De Jong, Bauke Ylstra, Matias Mendeville, Ulrich Dührsen, Andreas Hüttmann, Christine Schmitz, Julia Richter, Wolfram Klapper, Otto S Hoekstra, Henrica C.W de Vet, Ronald Boellaard, Josée M Zijlstra
Journal: Blood
Blood (2021) 138 (Supplement 1): 451.
https://doi.org/10.1182/blood-2021-145855
Published: 2021
Journal Articles

The Combination of High Total Metabolic Tumor Volume and Poor ECOG Performance Status Defines Ultra-High Risk Diffuse Large B-Cell Lymphoma. Validation across Multiple Cohorts of Large Clinical Trials and in Real World

Catherine Thieblemont, MD PhD, Loïc Chartier, Ulrich Dührsen, Prof, MD PhD, Umberto Vitolo, MD, Sally F Barrington, Prof, MD PhD, Laetitia Vercellino, Jan Zaucha, MDPhD, Inês Patrocinio Carvalho, Gomes da Silva Maria, MD PhD, Pierre Decazes, Pierre-Julien Viailly, Herve Tilly, MD PhD, Alina Berriolo-Riedinger, Rene-Olivier Casasnovas, MD, Andreas Hüttmann, MD, Hajira Ilyas, George Mikhaeel, Prof, MD PhD, Joel Dunn, Anne Ségolène Cottereau, MD, Christine Schmitz, MD, Joseph N. Paulson, Tina G Nielsen, Michel Meignan, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30–31.
https://doi.org/10.1182/blood-2020-136544
Published: 2020
Journal Articles

The Optimal Timing of Interim 18F-FDG PET in Diffuse Large B-Cell Lymphoma: An Individual Patient Data Meta-Analysis By the Petra Consortium

Jakoba J Eertink, MSc, Coreline N Burggraaff, MD, Martijn W Heymans, PhD, Sally F Barrington, Prof, MD PhD, George Mikhaeel, Prof, MD PhD, Ulrich Dührsen, Prof, MD PhD, Andreas Hüttmann, MD, Luca Ceriani, MD, Emanuele Zucca, MD, Robert Carr, MD, Tamás Györke, MD PhD, Stefano Fanti, Prof, MD PhD, Howard R Higley, PhD, Michael V Knopp, MD PhD, Heiko Schöder, MD, Annika Loft, MD PhD, Martin Hutchings, MD PhD, Lale Kostakoglu, Prof, MD PhD, Pieternella Lugtenburg, MD PhD, Sanne E Wiegers, MSc, Simone Pieplenbosch, MSc, Ronald Boellaard, MSc, PhD, Otto S Hoekstra, MD PhD, Josée M Zijlstra, MD PhD, Henrica C.W. de Vet, Prof, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 487.
https://doi.org/10.1182/blood-2019-122298
Published: 2019
Journal Articles

Azacitidine for Pre-Emptive Treatment of Measurable-Residual Disease in MDS/AML Patients at High Risk of Hematological Relapse: Results of the Second Cohort of the RELAZA2 Trial

Uwe Platzbecker, MD, Jan Moritz Middeke, MD, Katja Sockel, MD, Regina Herbst, MD, Lars R. Fransecky, MD, Dominik Wolf, MD, Schumacher Martin, MD, Alwin Krämer, MD, Richard Noppeney, MD, Juergen Novotny, MD, Gesine Bug, Katharina Götze, Karsten Spiekermann, MD, Matthias Stelljes, MD, Christoph Groth, MD, Marion Subklewe, MD, Antje Schubert, Anke Mütherig, MD, Tilmann Bochtler, MD, Marika Mende, MD, Anne Sophie Kubasch, MD, Mathias Hänel, MD, Ulrich Dührsen, Prof, MD PhD, Johannes Schetelig, MD MSc, Christoph Röllig, MD MSC, Claudia D Baldus, Gerhard Ehninger, MD, Carsten Müller-Tidow, MD, Hubert Serve, MD, Michael Kramer, M.Sc., Martin Bornhäuser, MD, Christian Thiede, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 644.
https://doi.org/10.1182/blood-2019-129926
Published: 2019
Journal Articles

Earlier Steroid Use with Axicabtagene Ciloleucel (Axi-Cel) in Patients with Relapsed/Refractory Large B Cell Lymphoma

Max Topp, MD, Tom Van Meerten, MD PhD, Roch Houot, MD PhD, Monique C. Minnema, Noel Milpied, MD, Pieternella J. Lugtenburg, MD PhD, Catherine Thieblemont, MD PhD, Martin Wermke, MD, Kevin Song, MD, Irit Avivi, MD, John Kuruvilla, MD, Ulrich Dührsen, Prof, MD PhD, Rachel Chu, PhD, Lianqing Zheng, PhD, Vicki Plaks, PhD, Anne Kerber, MD, Marie Jose' Kersten, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 243.
https://doi.org/10.1182/blood-2019-126081
Published: 2019
Journal Articles

Short Diagnosis-to-Treatment Interval Is Associated with Higher Levels of Circulating Tumor DNA in Aggressive B-Cell Non-Hodgkin Lymphoma

Stefan Alig, MD, Charles Macaulay, MSc, BA, David M. Kurtz, MD PhD, Ulrich Dührsen, Prof, MD PhD, Andreas Hüttmann, MD, Michael C. Jin, BS, Brian Sworder, MD PhD, Andrea Garofalo, BS, BA, Mohammad Shahrokh Esfahani, Joanne Soo, MD, Florian Scherer, MD, Alexander Craig, MPhil, Olivier Casasnovas, MD, Jason R. Westin, MD, Gianluca Gaidano, MD PhD, Davide Rossi, MD PhD, Maximilian Diehn, MD PhD, Ash A. Alizadeh, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 491.
https://doi.org/10.1182/blood-2019-129283
Published: 2019
Journal Articles

A CXCL10/CXCR3 Driven Thymic Epithelium-Leukemia Cell Crosstalk Augments T Cell Acute Lymphoblastic Leukemia Notch1 Signalling

Ashwini M Patil, MSc, Stefanie Kesper, Vishal Khairnar, PhD, Marco Luciani, Michael Möllmann, Ulrich Dührsen, Prof, MD PhD, Joachim R Göthert, PD, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2537.
https://doi.org/10.1182/blood-2019-125331
Published: 2019
Journal Articles

Bortezomib-Based Induction and Maintenance Overcomes the Negative Prognostic Impact of Renal Impairment and del17p in Transplant-Eligible Myeloma Patients: Long Term Results from the Phase III HOVON-65/GMMG-HD4 Study after Median 137 Months Follow up

Christof Scheid, MD, Henk Lokhorst, MD PhD, Igor W Blau, MD PhD, Bronno Van Der Holt, PhD, Uta Bertsch, Sonja Zweegman, MD PhD, Katja Weisel, Edo Vellenga, Marie José Kersten, MD PhD, Sandra Croockewit, Elias K Mai, MD, Reinier Raymakers, MD PhD, Dirk Hose, MD, Anna Jauch, Jens Hillengass, MD, Marian Stevens-Kroef, PhD, Marc S Raab, MD PhD, Kai Neben, Stephan Stilgenbauer, Annemiek Broyl, MD PhD, Hans-Walter Lindemann, MD, Gerard Bos, MD PhD, Peter Brossart, MD, Marinus van Marwijk Kooij, MD PhD, Paula F Ypma, MD PhD, Ulrich Dührsen, Prof, MD PhD, Ron Schaafsma, MD PhD, Thomas Hielscher, Hans Salwender, Hartmut Goldschmidt, MD, Pieter Sonneveld
Journal: Blood
Blood (2019) 134 (Supplement_1): 3308.
https://doi.org/10.1182/blood-2019-129684
Published: 2019
Journal Articles

Lymphoma Virome Dynamics Revealed By Cell-Free DNA Sequencing

Joseph G Schroers-Martin, MD, Andrea Garofalo, Joanne Soo, BS, Michael C. Jin, David M. Kurtz, MDPhD, Lieselot Buedts, Ulrich Dührsen, Prof, MD PhD, Andreas Hüttmann, MD, Anne Ségolène Cottereau, Michel Meignan, Olivier Casasnovas, MD, Jason R. Westin, MD, Gianluca Gaidano, MD PhD, Davide Rossi, MD PhD, Mark Roschewski, MD, Wyndham H. Wilson, MD PhD, Ranjana H Advani, MD, Peter Vandenberghe, MD, Maximilian Diehn, MD PhD, Kiran Khush, MD, Ash A. Alizadeh, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2861.
https://doi.org/10.1182/blood-2018-99-119905
Published: 2018
Journal Articles

A Global, Randomized, Placebo-Controlled, Phase 3 Study of Ibrutinib Plus Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (RCHOP) in Patients with Previously Untreated Non-Germinal Center B-Cell-like (GCB) Diffuse Large B-Cell Lymphoma (DLBCL)

Anas Younes, MD, Laurie H Sehn, MDMPH, Peter Johnson, MD, Pier Luigi Zinzani, MD, Xiaonan Hong, MD, Jun Zhu, Olga Samoilova, MD, Cheolwon Suh, Itaru Matsumura, MD, Andres Lopez-Hernandez, MD, Ulrich Dührsen, Prof, MD PhD, Catherine Thieblemont, MD, Jodi Carey, BSN, RN, Grace Liu, PhD, S. Martin Shreeve, MD PhD, Steven Sun, PhD, Jessica Vermeulen, Louis M. Staudt, MD PhD, Wyndham H. Wilson, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 784.
https://doi.org/10.1182/blood-2018-99-112988
Published: 2018
Journal Articles

Pharmacologic LSD1 Inhibition Preserves Human Granulocytic While Expanding Monocytic Progenitors

Karlotta E Kahmann, Stefanie Kesper, Marco Luciani, Michael Möllmann, Hugh Y. Rienhoff, Jr., MD, Ulrich Dührsen, Prof, MD PhD, Joachim R Göthert, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2645.
https://doi.org/10.1182/blood-2018-99-113887
Published: 2018
Journal Articles

Long-Term Survival after Transplantation in Patients with Chronic Myeloid Leukemia from HLA-Compatible Unrelated Donors: May the Stem Cell Source Influence the Outcome?

Michael Koldehoff, Prof, MD PhD, Ahmet H. Elmaagacli, Prof, MD PhD, Hellmut Dietmar Ottinger, MD PhD, Ulrich Dührsen, Prof, MD PhD, Dietrich W. Beelen
Journal: Blood
Blood (2018) 132 (Supplement 1): 5775.
https://doi.org/10.1182/blood-2018-99-118615
Published: 2018
Journal Articles

Noninvasive Genotyping and Monitoring of Classical Hodgkin Lymphoma

Michael C. Jin, Joseph G Schroers-Martin, MD, David M. Kurtz, MD PhD, Lieselot Buedts, Mohammad S Esfahani, PhD, Charles Macaulay, BS, Brian Sworder, MD PhD, Joanne Soo, BS, Cynthia Glover, Mark Roschewski, MD, Wyndham H. Wilson, MD PhD, Ulrich Dührsen, Prof, MD PhD, Andreas Hüttmann, MD, Davide Rossi, MD PhD, Gianluca Gaidano, MD PhD, Jason R. Westin, MD, Lauren S. Maeda, MD, Ranjana H Advani, MD, Peter Vandenberghe, MD, Maximilian Diehn, MD PhD, Arash A. Alizadeh, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2838.
https://doi.org/10.1182/blood-2018-99-119140
Published: 2018
Journal Articles

A Predictive Score for Early Mortality during Induction Therapy in Newly Diagnosed Transplant-Eligible Multiple Myeloma - an Analysis from Five GMMG and HOVON Multicenter Phase III Trials

Elias K Mai, MD, Thomas Hielscher, PhD, Uta Bertsch, MD, Jana Schlenzka, MD, Hans Jürgen Salwender, Henk M Lokhorst, Markus Munder, MD, Bronno van der Holt, Christian Gerecke, MD, Michael Pfreundschuh, MD, Ulrich Duhrsen, Peter Brossart, MD, Sonja Zweegman, MD PhD, Kai Neben, Jens Hillengass, MD, Marc-Steffen S Raab, Dirk Hose, MD, Edo Vellenga, MD, Maximilian Merz, MD, Iris Breitkreutz, MD, Anna Jauch, Marie José Kersten, MD, Hans Martin, Hans-Walter Lindemann, Norma Peter, MD, Sandra Croockewit, MD, Igor Wolfgang Blau, MD, Christof Scheid, MD, Katja C. Weisel, Pieter Sonneveld, MDPhD, Hartmut Goldschmidt, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2016.
https://doi.org/10.1182/blood.V130.Suppl_1.2016.2016
Published: 2017
Journal Articles

GFI1b As a Novel Oncosuppressor in AML

Aniththa Thivakaran, M.Sc., Lacramioara Botezatu, PhD, Judith Maria Hoenes, M.Sc., Yahya Saleh Al-Matary, MSc, Nadine Olberding, B.Sc, Judith Schütte, PhD, Renata Köster, Bertram Opalka, PhD, Ulrich Dührsen, MD, Cyrus Khandanpour, MD
Journal: Blood
Blood (2016) 128 (22): 2717.
https://doi.org/10.1182/blood.V128.22.2717.2717
Published: 2016