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Journal Articles

Resistance to Bruton tyrosine kinase inhibitors: the Achilles heel of their success story in lymphoid malignancies

Clinical Trials & Observations
Deborah M. Stephens, John C. Byrd
Journal: Blood
Blood (2021) 138 (13): 1099–1109.
https://doi.org/10.1182/blood.2020006783
Published: 2021
Journal Articles

Cell cycle control in Richter transformation

Christian P. Pallasch
Journal: Blood
Blood (2021) 138 (12): 1005–1007.
https://doi.org/10.1182/blood.2021011648
Published: 2021
Journal Articles

What’s new in the pathogenesis and treatment of therapy-related myeloid neoplasms

Maria Teresa Voso, Giulia Falconi, Emiliano Fabiani
Journal: Blood
Blood (2021) 138 (9): 749–757.
https://doi.org/10.1182/blood.2021010764
Published: 2021
Journal Articles

Genetic identification of patients with AML older than 60 years achieving long-term survival with intensive chemotherapy

CME Clinical Trials & Observations
Raphael Itzykson, Elise Fournier, Céline Berthon, Christoph Röllig, Thorsten Braun, Alice Marceau-Renaut, Cécile Pautas, Olivier Nibourel, Emilie Lemasle, Jean-Baptiste Micol, Lionel Adès, Delphine Lebon, Jean-Valère Malfuson, Lauris Gastaud, Laure Goursaud, Emmanuel Raffoux, Kevin-James Wattebled, Philippe Rousselot, Xavier Thomas, Sylvain Chantepie, Thomas Cluzeau, Hubert Serve, Nicolas Boissel, Christine Terré, Karine Celli-Lebras, Claude Preudhomme, Christian Thiede, Hervé Dombret, Claude Gardin, Nicolas Duployez
Journal: Blood
Blood (2021) 138 (7): 507–519.
https://doi.org/10.1182/blood.2021011103
Published: 2021
Includes: Supplemental data
Journal Articles

The chromatin remodeler CHD8 governs hematopoietic stem/progenitor survival by regulating ATM-mediated P53 protein stability

Zhaowei Tu, Chen Wang, Ashley K. Davis, Mengwen Hu, Chuntao Zhao, Mei Xin, Q. Richard Lu, Yi Zheng
Journal: Blood
Blood (2021) 138 (3): 221–233.
https://doi.org/10.1182/blood.2020009997
Published: 2021
Includes: Supplemental data
Journal Articles

CLL-IPI: valid in the era of oral inhibitors?

Nadine Kutsch
Journal: Blood
Blood (2021) 138 (2): 106–107.
https://doi.org/10.1182/blood.2021011937
Published: 2021
Journal Articles

Preexisting and treatment-emergent autoimmune cytopenias in patients with CLL treated with targeted drugs

Clinical Trials & Observations
Candida Vitale, Chiara Salvetti, Valentina Griggio, Marika Porrazzo, Luana Schiattone, Giulia Zamprogna, Andrea Visentin, Francesco Vassallo, Ramona Cassin, Gian Matteo Rigolin, Roberta Murru, Luca Laurenti, Paolo Rivela, Monia Marchetti, Elsa Pennese, Massimo Gentile, Elia Boccellato, Francesca Perutelli, Maria Chiara Montalbano, Lorenzo De Paoli, Gianluigi Reda, Lorella Orsucci, Livio Trentin, Antonio Cuneo, Alessandra Tedeschi, Lydia Scarfò, Gianluca Gaidano, Francesca Romana Mauro, Robin Foà, Mario Boccadoro, Marta Coscia
Journal: Blood
Blood (2021) 137 (25): 3507–3517.
https://doi.org/10.1182/blood.2020008201
Published: 2021
Includes: Supplemental data
Journal Articles

Targeting MCL-1 and BCL-2: a 1-2 punch

Jennifer R. Brown
Journal: Blood
Blood (2021) 137 (20): 2711–2712.
https://doi.org/10.1182/blood.2021012001
Published: 2021
Journal Articles

Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias

Rachel Thijssen, Sarah T. Diepstraten, Donia Moujalled, Edward Chew, Christoffer Flensburg, Melissa X. Shi, Michael A. Dengler, Veronique Litalien, Sarah MacRaild, Maoshan Chen, Natasha S. Anstee, Boris Reljić, Sarah S. Gabriel, Tirta M. Djajawi, Chris D. Riffkin, Brandon J. Aubrey, Catherine Chang, Lin Tai, Zhen Xu, Thomas Morley, Giovanna Pomilio, Claudia Bruedigam, Axel Kallies, David A. Stroud, Ashish Bajel, Ruth M. Kluck, Steven W. Lane, Marie Schoumacher, Sébastien Banquet, Ian J. Majewski, Andreas Strasser, Andrew W. Roberts, David C. S. Huang, Fiona C. Brown, Gemma L. Kelly, Andrew H. Wei
Journal: Blood
Blood (2021) 137 (20): 2721–2735.
https://doi.org/10.1182/blood.2020010167
Published: 2021
Includes: Supplemental data
Journal Articles

Mutational landscape of gray zone lymphoma

Clémentine Sarkozy, Stacy S. Hung, Elizabeth A. Chavez, Gerben Duns, Katsuyoshi Takata, Lauren C. Chong, Tomohiro Aoki, Aixiang Jiang, Tomoko Miyata-Takata, Adèle Telenius, Graham W. Slack, Thierry Jo Molina, Susana Ben-Neriah, Pedro Farinha, Peggy Dartigues, Diane Damotte, Anja Mottok, Gilles A. Salles, Rene-Olivier Casasnovas, Kerry J. Savage, Camille Laurent, David W. Scott, Alexandra Traverse-Glehen, Christian Steidl
Journal: Blood
Blood (2021) 137 (13): 1765–1776.
https://doi.org/10.1182/blood.2020007507
Published: 2021
Includes: Supplemental data
Journal Articles

Deletion 17p: a matter of size and number?

Sonja Zweegman, Niels W. C. J. van de Donk
Journal: Blood
Blood (2021) 137 (9): 1135–1136.
https://doi.org/10.1182/blood.2020009102
Published: 2021
Journal Articles

Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers

Alexandre Fagnan, Frederik Otzen Bagger, Maria-Riera Piqué-Borràs, Cathy Ignacimouttou, Alexis Caulier, Cécile K. Lopez, Elie Robert, Benjamin Uzan, Véronique Gelsi-Boyer, Zakia Aid, Cécile Thirant, Ute Moll, Samantha Tauchmann, Amina Kurtovic-Kozaric, Jaroslaw Maciejewski, Christine Dierks, Orietta Spinelli, Silvia Salmoiraghi, Thomas Pabst, Kazuya Shimoda, Virginie Deleuze, Hélène Lapillonne, Connor Sweeney, Véronique De Mas, Betty Leite, Zahra Kadri, Sébastien Malinge, Stéphane de Botton, Jean-Baptiste Micol, Benjamin Kile, Catherine L. Carmichael, Ilaria Iacobucci, Charles G. Mullighan, Martin Carroll, Peter Valent, Olivier A. Bernard, Eric Delabesse, Paresh Vyas, Daniel Birnbaum, Eduardo Anguita, Loïc Garçon, Eric Soler, Juerg Schwaller, Thomas Mercher
Journal: Blood
Blood (2020) 136 (6): 698–714.
https://doi.org/10.1182/blood.2019003062
Published: 2020
Includes: Supplemental data
Journal Articles

The different flavors and splices of MCL

Oliver Weigert
Journal: Blood
Blood (2020) 136 (5): 526–527.
https://doi.org/10.1182/blood.2020005591
Published: 2020
Journal Articles

Coding and noncoding drivers of mantle cell lymphoma identified through exome and genome sequencing

Prasath Pararajalingam, Krysta M. Coyle, Sarah E. Arthur, Nicole Thomas, Miguel Alcaide, Barbara Meissner, Merrill Boyle, Quratulain Qureshi, Bruno M. Grande, Christopher Rushton, Graham W. Slack, Andrew J. Mungall, Constantine S. Tam, Rishu Agarwal, Sarah-Jane Dawson, Georg Lenz, Sriram Balasubramanian, Randy D. Gascoyne, Christian Steidl, Joseph Connors, Diego Villa, Timothy E. Audas, Marco A. Marra, Nathalie A. Johnson, David W. Scott, Ryan D. Morin
Journal: Blood
Blood (2020) 136 (5): 572–584.
https://doi.org/10.1182/blood.2019002385
Published: 2020
Includes: Supplemental data
Journal Articles

Prognostic and predictive impact of genetic markers in patients with CLL treated with obinutuzumab and venetoclax

Clinical Trials & Observations
Eugen Tausch, Christof Schneider, Sandra Robrecht, Can Zhang, Anna Dolnik, Johannes Bloehdorn, Jasmin Bahlo, Othman Al-Sawaf, Matthias Ritgen, Anna-Maria Fink, Barbara Eichhorst, Karl-Anton Kreuzer, Maneesh Tandon, Kathryn Humphrey, Yanwen Jiang, William Schary, Lars Bullinger, Daniel Mertens, Michele Porro Lurà, Michael Kneba, Hartmut Döhner, Kirsten Fischer, Michael Hallek, Stephan Stilgenbauer
Journal: Blood
Blood (2020) 135 (26): 2402–2412.
https://doi.org/10.1182/blood.2019004492
Published: 2020
Includes: Supplemental data
Journal Articles

A predictive tool for early-stage CLL

Constantine S. Tam, John F. Seymour
Journal: Blood
Blood (2020) 135 (21): 1820–1821.
https://doi.org/10.1182/blood.2020005426
Published: 2020
Journal Articles

Mutational spectrum and dynamics of clonal hematopoiesis in anemia of older individuals

Isabelle A. van Zeventer, Aniek O. de Graaf, Hanneke J. C. M. Wouters, Bert A. van der Reijden, Melanie M. van der Klauw, Theo de Witte, Marianne A. Jonker, Luca Malcovati, Joop H. Jansen, Gerwin Huls
Journal: Blood
Blood (2020) 135 (14): 1161–1170.
https://doi.org/10.1182/blood.2019004362
Published: 2020
Includes: Supplemental data
Journal Articles

Baseline TP53 mutations in adults with SCD developing myeloid malignancy following hematopoietic cell transplantation

Clinical Trials & Observations
Jack Y. Ghannam, Xin Xu, Irina Maric, Laura Dillon, Yuesheng Li, Matthew M. Hsieh, Christopher S. Hourigan, Courtney D. Fitzhugh
Journal: Blood
Blood (2020) 135 (14): 1185–1188.
https://doi.org/10.1182/blood.2019004001
Published: 2020
Journal Articles

Integrative analysis of spontaneous CLL regression highlights genetic and microenvironmental interdependency in CLL

Clinical Trials & Observations
Marwan Kwok, Ceri Oldreive, Andy C. Rawstron, Anshita Goel, Grigorios Papatzikas, Rhiannon E. Jones, Samantha Drennan, Angelo Agathanggelou, Archana Sharma-Oates, Paul Evans, Edward Smith, Surita Dalal, Jingwen Mao, Robert Hollows, Naheema Gordon, Mayumi Hamada, Nicholas J. Davies, Helen Parry, Andrew D. Beggs, Talha Munir, Paul Moreton, Shankara Paneesha, Guy Pratt, A. Malcolm R. Taylor, Francesco Forconi, Duncan M. Baird, Jean-Baptiste Cazier, Paul Moss, Peter Hillmen, Tatjana Stankovic
Journal: Blood
Blood (2020) 135 (6): 411–428.
https://doi.org/10.1182/blood.2019001262
Published: 2020
Includes: Supplemental data
Journal Articles

Distinct molecular profile of IRF4 -rearranged large B-cell lymphoma

Joan Enric Ramis-Zaldivar, Blanca Gonzalez-Farré, Olga Balagué, Verónica Celis, Ferran Nadeu, Julia Salmerón-Villalobos, Mara Andrés, Idoia Martin-Guerrero, Marta Garrido-Pontnou, Ayman Gaafar, Mariona Suñol, Carmen Bárcena, Federico Garcia-Bragado, Maitane Andión, Daniel Azorín, Itziar Astigarraga, Maria Sagaseta de Ilurdoz, Constantino Sábado, Soledad Gallego, Jaime Verdú-Amorós, Rafael Fernandez-Delgado, Vanesa Perez, Gustavo Tapia, Anna Mozos, Montserrat Torrent, Palma Solano-Páez, Alfredo Rivas-Delgado, Ivan Dlouhy, Guillem Clot, Anna Enjuanes, Armando López-Guillermo, Pallavi Galera, Matthew J. Oberley, Alanna Maguire, Colleen Ramsower, Lisa M. Rimsza, Leticia Quintanilla-Martinez, Elaine S. Jaffe, Elías Campo, Itziar Salaverria
Journal: Blood
Blood (2020) 135 (4): 274–286.
https://doi.org/10.1182/blood.2019002699
Published: 2020
Includes: Supplemental data