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Journal Articles

GATA2 links stemness to chemotherapy resistance in acute myeloid leukemia

Blood (2025) 145 (19): 2179–2195.

https://doi.org/10.1182/blood.2024025761

Published: 2025

Includes: Supplemental data

Journal Articles

ANKRD26-related Thrombocytopenia 2 with a Baseline Increase in Blasts: Implications for Clinical Surveillance

Lara Wahlster, Lucy A Godley, Jason X Cheng, Michael W Drazer, Christopher R. Reilly, Geraldine S Pinkus, Jared H Rowe, Nina Weichert-Leahey, Robert Grant Rowe, Lev Gorfinkel, Karyn Jean Brundige, Franziska Wachter, Luana Miria Messa, Alan D Michelson, Alan B. Cantor, Akiko Shimamura, Jacob R Bledsoe

Blood blood.2024027368.

https://doi.org/10.1182/blood.2024027368

Published: 2025

Includes: Supplemental data

Journal Articles

Decoding functional hematopoietic progenitor cells in the adult human lung

Catharina Conrad, Mélia Magnen, Jessica Tsui, Harrison Wismer, Mohammad Naser, Urmila Venkataramani, Bushra Samad, Simon J. Cleary, Longhui Qiu, Jennifer J. Tian, Marco De Giovanni, Nicole Mende, Andrew D. Leavitt, Emmanuelle Passegué, Elisa Laurenti, Alexis J. Combes, Mark R. Looney

Blood (2025) 145 (18): 1975–1986.

https://doi.org/10.1182/blood.2024027884

Published: 2025

Includes: Supplemental data

Journal Articles

Coordinated regulation of self-renewal and cell cycle during human lympho-myeloid lineage restriction

Fangwu Wang, Laura Gonzalez, Qiuyu Lian, Colin A Hammond, Yasmine Y.M. Lau, Benjamin D. Simons, Martin Hirst, Connie J Eaves

Blood blood.2024026936.

https://doi.org/10.1182/blood.2024026936

Published: 2025

Includes: Supplemental data

Journal Articles

Heterogeneity of high-potency multilineage hematopoietic stem cells and identification of 'Super' transplantability

Blood blood.2024027872.

https://doi.org/10.1182/blood.2024027872

Published: 2025

Includes: Supplemental data

Journal Articles

An unbiased genomewide screen uncovers 7 genes that drive hematopoietic stem cell fate from mouse embryonic stem cells

Luis Galan Palma, PhD, Gayathri M Kartha, Maria Maqueda, Mercedes Barrero, Eric Canton, Arnau Iglesias, Jessica Gonzalez Miranda, Patricia Herrero Molinero, Raul Torres-Ruíz, Bernhard Payer, Clara Bueno, Pablo Menendez, Lluis Espinosa, Anna Bigas

Blood blood.2024027742.

https://doi.org/10.1182/blood.2024027742

Published: 2025

Includes: Supplemental data

Journal Articles

IL-1R1 and IL-18 signals regulate mesenchymal stromal cells in an aged murine model of myelodysplastic syndromes

Yuko Kawano, Hiroki Kawano, Mark W. LaMere, Elizabeth A. LaMere, Daniel K. Byun, Kathleen E. McGrath, James Palis, Jeevisha Bajaj, Jane L. Liesveld, Yoshio Katayama, Satoshi Yamazaki, Reuben Kapur, Laura M. Calvi, Tzu-Chieh Ho, Michael W. Becker

Blood (2025) 145 (15): 1632–1644.

https://doi.org/10.1182/blood.2024024818

Published: 2025

Includes: Supplemental data

Journal Articles

Progressive chromatin rewiring by ETO2::GLIS2 revealed in a genome-edited human iPSC model of pediatric leukemia initiation

Blood (2025) 145 (14): 1510–1525.

https://doi.org/10.1182/blood.2024024505

Published: 2025

Includes: Supplemental data

Journal Articles

Tracking clusterin expression in hematopoietic stem cells reveals their heterogeneous composition across the lifespan

Blood blood.2024025776.

https://doi.org/10.1182/blood.2024025776

Published: 2025

Includes: Supplemental data

Journal Articles

Population dynamics modeling reveals that myeloid bias involves both HSC differentiation and progenitor proliferation biases

Apeksha Singh, Jennifer J. Chia, Dinesh S. Rao, Alexander Hoffmann

Blood (2025) 145 (12): 1293–1308.

https://doi.org/10.1182/blood.2024025598

Published: 2025

Includes: Supplemental data

Journal Articles

Proteostasis Disruption in Inherited Bone Marrow Failure Syndromes

Helena Yu, Robert Signer

Blood blood.2024024956.

https://doi.org/10.1182/blood.2024024956

Published: 2025

Journal Articles

Pathogenesis of Paroxysmal Nocturnal Hemoglobinuria

Lucio Luzzatto, Shinji Nakao

Blood blood.2024025975.

https://doi.org/10.1182/blood.2024025975

Published: 2025

Journal Articles

Single-cell panleukemia signatures of HSPC-like blasts predict drug response and clinical outcome

Blood blood.2024027270.

https://doi.org/10.1182/blood.2024027270

Published: 2025

Includes: Supplemental data

Journal Articles

Single-cell epigenetic and clonal analysis decodes disease progression in pediatric acute myeloid leukemia

Boyu Cui, Lanlan Ai, Minghui Lei, Yongjuan Duan, Chao Tang, Jingliao Zhang, Yan Gao, Xuan Li, Caiying Zhu, Yingchi Zhang, Xiaofan Zhu, Tomoya Isobe, Wenyu Yang, Berthold Göttgens, Ping Zhu

Blood (2025) 145 (11): 1211–1224.

https://doi.org/10.1182/blood.2024025618

Published: 2025

Includes: Supplemental data

Journal Articles

Selenoprotein-mediated redox regulation shapes the cell fate of HSCs and mature lineages

Blood (2025) 145 (11): 1149–1163.

https://doi.org/10.1182/blood.2024025402

Published: 2025

Includes: Supplemental data

Journal Articles

Cullin-5 controls the number of megakaryocyte-committed stem cells to prevent thrombocytosis in mice

Maria Kauppi, Craig D. Hyland, Elizabeth M. Viney, Christine A. White, Carolyn A. de Graaf, AnneMarie E. Welch, Jumana Yousef, Laura F. Dagley, Samantha J. Emery-Corbin, Ladina Di Rago, Andrew J. Kueh, Marco J. Herold, Douglas J. Hilton, Jeffrey J. Babon, Nicos A. Nicola, Kira Behrens, Warren S. Alexander

Blood (2025) 145 (10): 1034–1046.

https://doi.org/10.1182/blood.2024025406

Published: 2025

Includes: Supplemental data

Journal Articles

Novel treatment strategies for chronic myeloid leukemia

Nataly Cruz-Rodriguez, Michael W. Deininger

Blood (2025) 145 (9): 931–943.

https://doi.org/10.1182/blood.2024026312

Published: 2025

Journal Articles

Methylation sequencing enhances interpretation of clonal hematopoiesis dynamics

Alyssa C. Parker, Joseph C. Van Amburg, J. Brett Heimlich, Yash Pershad, Nicole A. Mickels, Taralynn M. Mack, P. Brent Ferrell, Michael R. Savona, Angela L. Jones, Alexander G. Bick

Blood (2025) 145 (9): 988–992.

https://doi.org/10.1182/blood.2024026555

Published: 2025

Includes: Supplemental data

Journal Articles

cMPL-Based Purification and Depletion of Human Hematopoietic Stem Cells: Implications for Pretransplant Conditioning

Daisuke Araki, So Gun Hong, Nathaniel Seth Linde, Bryan Fisk, Neelam Redekar, Christi T Salisbury-Ruf, Allen Krouse, Theresa Engels, Justin Golomb, Pradeep K Dagur, Sumith R Panicker, Yogendra Kanthi, Diogo Magnani, Zhirui Wang, Andre Larochelle

Blood blood.2024024636.

https://doi.org/10.1182/blood.2024024636

Published: 2025

Includes: Supplemental data

Journal Articles

BRAFV600E induces key features of LCH in iPSCs with cell type–specific phenotypes and drug responses

Giulio Abagnale, Raphaela Schwentner, Philipp Ben Soussia-Weiss, Wouter van Midden, Caterina Sturtzel, Ulrike Pötschger, Magdalena Rados, Sabine Taschner-Mandl, Ingrid Simonitsch-Klupp, Christoph Hafemeister, Florian Halbritter, Martin Distel, Sebastian K. Eder, Caroline Hutter

Blood (2025) 145 (8): 850–865.

https://doi.org/10.1182/blood.2024026066

Published: 2025

Includes: Supplemental data

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GATA2 links stemness to chemotherapy resistance in acute myeloid leukemia

ANKRD26-related Thrombocytopenia 2 with a Baseline Increase in Blasts: Implications for Clinical Surveillance

Decoding functional hematopoietic progenitor cells in the adult human lung

Coordinated regulation of self-renewal and cell cycle during human lympho-myeloid lineage restriction

Heterogeneity of high-potency multilineage hematopoietic stem cells and identification of 'Super' transplantability

An unbiased genomewide screen uncovers 7 genes that drive hematopoietic stem cell fate from mouse embryonic stem cells

IL-1R1 and IL-18 signals regulate mesenchymal stromal cells in an aged murine model of myelodysplastic syndromes

Progressive chromatin rewiring by ETO2::GLIS2 revealed in a genome-edited human iPSC model of pediatric leukemia initiation

Tracking clusterin expression in hematopoietic stem cells reveals their heterogeneous composition across the lifespan

Population dynamics modeling reveals that myeloid bias involves both HSC differentiation and progenitor proliferation biases

Proteostasis Disruption in Inherited Bone Marrow Failure Syndromes

Pathogenesis of Paroxysmal Nocturnal Hemoglobinuria

Single-cell panleukemia signatures of HSPC-like blasts predict drug response and clinical outcome

Single-cell epigenetic and clonal analysis decodes disease progression in pediatric acute myeloid leukemia

Selenoprotein-mediated redox regulation shapes the cell fate of HSCs and mature lineages

Cullin-5 controls the number of megakaryocyte-committed stem cells to prevent thrombocytosis in mice

Novel treatment strategies for chronic myeloid leukemia

Methylation sequencing enhances interpretation of clonal hematopoiesis dynamics

cMPL-Based Purification and Depletion of Human Hematopoietic Stem Cells: Implications for Pretransplant Conditioning

BRAFV600E induces key features of LCH in iPSCs with cell type–specific phenotypes and drug responses

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