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The promises and challenges of using gene mutations for patient stratification in follicular lymphoma
How I treat myeloma with new agents
Randomized phase 2 study of low-dose decitabine vs low-dose azacitidine in lower-risk MDS and MDS/MPN
Delineation of the timing of second-line therapy post–autologous stem cell transplant in patients with AL amyloidosis
Increased risk of leukemia among sickle cell disease patients in California
Issue Archive
September 28 2017
Table of Contents
INSIDE BLOOD COMMENTARIES
PERSPECTIVES
The promises and challenges of using gene mutations for patient stratification in follicular lymphoma
Clinical Trials & Observations
REVIEW ARTICLE
HOW I TREAT
How I treat myeloma with new agents
Clinical Trials & Observations
CLINICAL TRIALS AND OBSERVATIONS
Randomized phase 2 study of low-dose decitabine vs low-dose azacitidine in lower-risk MDS and MDS/MPN
Clinical Trials & Observations
Elias Jabbour,Nicholas J. Short,Guillermo Montalban-Bravo,Xuelin Huang,Carlos Bueso-Ramos,Wei Qiao,Hui Yang,Chong Zhao,Tapan Kadia,Gautam Borthakur,Naveen Pemmaraju,Koji Sasaki,Zeev Estrov,Jorge Cortes,Farhad Ravandi,Yesid Alvarado,Rami Komrokji,Mikkael A. Sekeres,David P. Steensma,Amy DeZern,Gail Roboz,Hagop Kantarjian,Guillermo Garcia-Manero
HEMATOPOIESIS AND STEM CELLS
Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions
Ana Martín-Pardillos,Anastasia Tsaalbi-Shtylik,Si Chen,Seka Lazare,Ronald P. van Os,Albertina Dethmers-Ausema,Nima Borhan Fakouri,Matthias Bosshard,Rossana Aprigliano,Barbara van Loon,Daniela C. F. Salvatori,Keiji Hashimoto,Celia Dingemanse-van der Spek,Masaaki Moriya,Lene Juel Rasmussen,Gerald de Haan,Marc H. G. P. Raaijmakers,Niels de Wind
Engraftment and in vivo proliferation advantage of gene-corrected mobilized CD34+ cells from Fanconi anemia patients
Paula Río,Susana Navarro,Guillermo Guenechea,Rebeca Sánchez-Domínguez,Maria Luisa Lamana,Rosa Yañez,Jose A. Casado,Parinda A. Mehta,Maria Roser Pujol,Jordi Surrallés,Sabine Charrier,Anne Galy,José C. Segovia,Cristina Díaz de Heredia,Julián Sevilla,Juan A. Bueren
IMMUNOBIOLOGY AND IMMUNOTHERAPY
An Fc-engineered CD19 antibody eradicates MRD in patient-derived MLL-rearranged acute lymphoblastic leukemia xenografts
Denis M. Schewe,Ameera Alsadeq,Cornelia Sattler,Lennart Lenk,Fotini Vogiatzi,Gunnar Cario,Simon Vieth,Thomas Valerius,Sophia Rosskopf,Fabian Meyersieck,Julia Alten,Martin Schrappe,Martin Gramatzki,Matthias Peipp,Christian Kellner
Novel nonsense gain-of-function NFKB2 mutations associated with a combined immunodeficiency phenotype
Hye Sun Kuehn,Julie E. Niemela,Karthik Sreedhara,Jennifer L. Stoddard,Jennifer Grossman,Christian A. Wysocki,M. Teresa de la Morena,Mary Garofalo,Jingga Inlora,Michael P. Snyder,David B. Lewis,Constantine A. Stratakis,Thomas A. Fleisher,Sergio D. Rosenzweig
PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS
TRANSPLANTATION
Delineation of the timing of second-line therapy post–autologous stem cell transplant in patients with AL amyloidosis
Clinical Trials & Observations
Yi L. Hwa,Rahma Warsame,Morie A. Gertz,Francis K. Buadi,Martha Q. Lacy,Shaji K. Kumar,David Dingli,Steve R. Zeldenrust,Nelson Leung,Susanne R. Hayman,Prashant Kapoor,Wilson I. Gonsalves,Taxiarchis V. Kourelis,Stephen Russell,Ronald S. Go,Miriam A. Hobbs,Amie L. Fonder,S. Vincent Rajkumar,Angela Dispenzieri
Replication and validation of genetic polymorphisms associated with survival after allogeneic blood or marrow transplant
Ezgi Karaesmen,Abbas A. Rizvi,Leah M. Preus,Philip L. McCarthy,Marcelo C. Pasquini,Kenan Onel,Xiaochun Zhu,Stephen Spellman,Christopher A. Haiman,Daniel O. Stram,Loreall Pooler,Xin Sheng,Qianqian Zhu,Li Yan,Qian Liu,Qiang Hu,Amy Webb,Guy Brock,Alyssa I. Clay-Gilmour,Sebastiano Battaglia,David Tritchler,Song Liu,Theresa Hahn,Lara E. Sucheston-Campbell
LETTER TO BLOOD
Increased risk of leukemia among sickle cell disease patients in California
Clinical Trials & Observations
BLOOD WORK
ERRATUM
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Cover Image
Cover Image
The Fc-engineered CD19 antibody CD19-DE is highly efficient in recruiting macrophages for antibody-mediated phagocytosis of acute lymphoblastic leukemia (ALL) cells. The image shows a live cell analysis of antibody-mediated phagocytosis of green fluorescent ALL cells by human macrophages. See the article by Schewe et al on page 1543.
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