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Issue Archive

Volume 96, Issue 13
December 15 2000
Blood Cover Image for Volume 96, Issue 13

Table of Contents

PLENARY PAPERS

Identification of alloreactive T-cell epitopes on the Rhesus D protein
Lisa-Marie Stott,Robert N. Barker,Stanislaw J. Urbaniak
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REVIEW ARTICLES

Iron homeostasis: new tales from the crypt
Cindy N. Roy,Caroline A. Enns
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The human basophil: a new appreciation of its role in immune responses
Franco H. Falcone,Helmut Haas,Bernhard F. Gibbs
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CHEMOKINES

I-309 binds to and activates endothelial cell functions and acts as an angiogenic molecule in vivo
Giovanni Bernardini,Gaia Spinetti,Domenico Ribatti,Grazia Camarda,Lucia Morbidelli,Marina Ziche,Angela Santoni,Maurizio C. Capogrossi,Monica Napolitano
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Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets
Kenneth J. Clemetson,Jeannine M. Clemetson,Amanda E. I. Proudfoot,Christine A. Power,Marco Baggiolini,Timothy N. C. Wells
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CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Characterization of Epstein-Barr virus–infected B cells in patients with posttransplantation lymphoproliferative disease: disappearance after rituximab therapy does not predict clinical response
Clinical Trials & Observations
Jie Yang,Qian Tao,Ian W. Flinn,Paul G. Murray,Linda E. Post,Hong Ma,Steven Piantadosi,Michael A. Caligiuri,Richard F. Ambinder
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Association of complementation group and mutation type with clinical outcome in Fanconi anemia
Clinical Trials & Observations
Laurence Faivre,Philippe Guardiola,Cathryn Lewis,Inderjeet Dokal,Wolfram Ebell,Ariana Zatterale,Cigdem Altay,Janet Poole,David Stones,Mei Lan Kwee,Margreet van Weel-Sipman,Charmaine Havenga,Neil Morgan,Johan de Winter,Martin Digweed,Anna Savoia,Jan Pronk,Thomas de Ravel,Stander Jansen,Hans Joenje,Eliane Gluckman,Christopher G. Mathew,for the European Fanconi Anemia Research Group
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Molecular characterization of a case of atransferrinemia
Clinical Trials & Observations
Ernest Beutler,Terri Gelbart,Pauline Lee,Reneé Trevino,Mark A. Fernandez,Virgil F. Fairbanks
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Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: a Southwest Oncology Group/Eastern Cooperative Oncology Group study
Clinical Trials & Observations
Marilyn L. Slovak,Kenneth J. Kopecky,Peter A. Cassileth,David H. Harrington,Karl S. Theil,Anwar Mohamed,Elizabeth Paietta,Cheryl L. Willman,David R. Head,Jacob M. Rowe,Stephen J. Forman,Frederick R. Appelbaum,for the Southwest Oncology Group and the Eastern Cooperative Oncology Group
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Evolving characteristics of AIDS-related lymphoma
Clinical Trials & Observations
Alexandra M. Levine,Lasika Seneviratne,Byron M. Espina,Amy Rock Wohl,Anil Tulpule,Bharat N. Nathwani,Parkash S. Gill
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Serum level of soluble urokinase-type plasminogen activator receptor is a strong and independent predictor of survival in human immunodeficiency virus infection
Clinical Trials & Observations
Nicolai Sidenius,Cornelis F. M. Sier,Henrik Ullum,Bente Klarlund Pedersen,Alessandro Cozzi Lepri,Francesco Blasi,Jesper Eugen-Olsen
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Engraftment and survival after unrelated-donor bone marrow transplantation: a report from the National Marrow Donor Program
Clinical Trials & Observations
Stella M. Davies,Craig Kollman,Claudio Anasetti,Joseph H. Antin,James Gajewski,James T. Casper,Auayporn Nademanee,Harriet Noreen,Roberta King,Dennis Confer,Nancy A. Kernan
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GENE THERAPY

The human immunodeficiency virus type-1 central DNA flap is a crucial determinant for lentiviral vector nuclear import and gene transduction of human hematopoietic stem cells
Aude Sirven,Françoise Pflumio,Véronique Zennou,Monique Titeux,William Vainchenker,Laure Coulombel,Anne Dubart-Kupperschmitt,Pierre Charneau
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Stable in vivo expression of glucose-6-phosphate dehydrogenase (G6PD) and rescue of G6PD deficiency in stem cells by gene transfer
Ana Rovira,Maria De Angioletti,Olga Camacho-Vanegas,Delong Liu,Vittorio Rosti,Humilidad F. Gallardo,Rosario Notaro,Michel Sadelain,Lucio Luzzatto
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HEMATOPOIESIS

Evidence that ceramide mediates the ability of tumor necrosis factor to modulate primitive human hematopoietic cell fates
Veronique Maguer-Satta,Robert Oostendorp,Dianne Reid,Connie J. Eaves
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Primitive hematopoietic stem cell function in vivo is uniquely high in the CXB-12 mouse strain
Jichun Chen,Clinton M. Astle,Christa E. Müller-Sieburg,David E. Harrison
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WNT signaling modulates the diversification of hematopoietic cells
Carlene Brandon,Leonard M. Eisenberg,Carol A. Eisenberg
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Stromal-derived factor 1 and thrombopoietin regulate distinct aspects of human megakaryopoiesis
Marcin Majka,Anna Janowska-Wieczorek,Janina Ratajczak,M. Anna Kowalska,Gaston Vilaire,Zhixing K. Pan,Marek Honczarenko,Leah A. Marquez,Mortimer Poncz,Mariusz Z. Ratajczak
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Stromal-derived factor 1–induced megakaryocyte migration and platelet production is dependent on matrix metalloproteinases
William J. Lane,Sergio Dias,Koichi Hattori,Beate Heissig,Margaret Choy,Sina Y. Rabbany,Jeanette Wood,Malcolm A. S. Moore,Shahin Rafii
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During ontogeny primitive (CD34+CD38−) hematopoietic cells show altered expression of a subset of genes associated with early cytokine and differentiation responses of their adult counterparts
Il-Hoan Oh,Aster Lau,Connie J. Eaves
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The αIIbβ3 integrin and GPIb-V-IX complex identify distinct stages in the maturation of CD34+cord blood cells to megakaryocytes
Adeline Lepage,Marylène Leboeuf,Jean-Pierre Cazenave,Corinne de la Salle,François Lanza,Georges Uzan
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Zebrafish homolog of the leukemia gene CBFB: its expression during embryogenesis and its relationship to scland gata-1 in hematopoiesis
Trevor Blake,Neeraj Adya,Cheol-Hee Kim,Andrew C. Oates,Leonard Zon,Ajay Chitnis,Brant M. Weinstein,P. Paul Liu
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Human hematopoietic stem cells stimulated to proliferate in vitro lose engraftment potential during their S/G2/M transit and do not reenter G0
Hanno Glimm,IL-Hoan Oh,Connie J. Eaves
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Characterization and functional analysis of laminin isoforms in human bone marrow
Ulrich Siler,Martina Seiffert,Sabine Puch,Allan Richards,Beverly Torok-Storb,Claudia A. Müller,Lydia Sorokin,Gerd Klein
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Interferon-γ–induced apoptotic responses of Fanconi anemia group C hematopoietic progenitor cells involve caspase 8–dependent activation of caspase 3 family members
R. Keaney Rathbun,Tracy A. Christianson,Gregory R. Faulkner,Gary Jones,Winifred Keeble,Michael O'Dwyer,Grover C. Bagby
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HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Plasminogen activator inhibitor-1 deficiency protects against atherosclerosis progression in the mouse carotid artery
Daniel T. Eitzman,Randal J. Westrick,Zuojun Xu,Julia Tyson,David Ginsburg
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Vascular endothelial growth factor–stimulated endothelial cells promote adhesion and activation of platelets
Henk M. W. Verheul,Anita S. Jorna,Klaas Hoekman,Henk J. Broxterman,Martijn F. B. G. Gebbink,Herbert M. Pinedo
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Spontaneous thrombosis in mice carrying the factor V Leiden mutation
Jisong Cui,Daniel T. Eitzman,Randal J. Westrick,Patricia D. Christie,Zuojun J. Xu,Angela Y. Yang,Anjali A. Purkayastha,Tony L. Yang,Alan L. Metz,Kim P. Gallagher,Julia A. Tyson,Robert D. Rosenberg,David Ginsburg
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Defects in the cappuccino (cno) gene on mouse chromosome 5 and human 4p cause Hermansky-Pudlak syndrome by an AP-3–independent mechanism
Babette Gwynn,Steven L. Ciciotte,Susan J. Hunter,Linda L. Washburn,Richard S. Smith,Sabra G. Andersen,Richard T. Swank,Esteban C. Dell'Angelica,Juan S. Bonifacino,Eva M. Eicher,Luanne L. Peters
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Human CLP36, a PDZ-domain and LIM-domain protein, binds to α-actinin-1 and associates with actin filaments and stress fibers in activated platelets and endothelial cells
Kristin Bauer,Michael Kratzer,Marcus Otte,Karin Luber de Quintana,Jörg Hagmann,Georg J. Arnold,Christoph Eckerskorn,Friedrich Lottspeich,Wolfgang Siess
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Fyn and Lyn phosphorylate the Fc receptor γ chain downstream of glycoprotein VI in murine platelets, and Lyn regulates a novel feedback pathway
Lynn S. Quek,Jean-Max Pasquet,Ingeborg Hers,Richard Cornall,Graham Knight,Michael Barnes,Margaret L. Hibbs,Ashley R. Dunn,Clifford A. Lowell,Steve P. Watson
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Thrombosis and shock induced by activating antiplatelet antibodies in human FcγRIIA transgenic mice: the interplay among antibody, spleen, and Fc receptor
Scott M. Taylor,Michael P. Reilly,Alan D. Schreiber,Paul Chien,Joseph R. Tuckosh,Steven E. McKenzie
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Polymorphonuclear leukocyte activation and hemostasis in patients with essential thrombocythemia and polycythemia vera
Anna Falanga,Marina Marchetti,Virgilio Evangelista,Alfonso Vignoli,Marina Licini,Mara Balicco,Stefano Manarini,Guido Finazzi,Chiara Cerletti,Tiziano Barbui
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IMMUNOBIOLOGY

Antiadhesive function of 130-kd glycoform of CD43 expressed in CD4 T-lymphocyte clones and transfectant cell lines
Mami Fukuoka,Kenji Fukudome,Yoshio Yamashita,Miyoko Tokushima,Kensuke Miyake,Masao Kimoto
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Ligation of E-cadherin on in vitro–generated immature Langerhans-type dendritic cells inhibits their maturation
Elisabeth Riedl,Johannes Stöckl,Otto Majdic,Clemens Scheinecker,Walter Knapp,Herbert Strobl
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Interferon α prevents spontaneous apoptosis of clonal Th2 cells associated with chronic hypereosinophilia
Liliane Schandené,Florence Roufosse,Aurore de Lavareille,Patrick Stordeur,André Efira,Bernard Kennès,Elie Cogan,Michel Goldman
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Immunologic dynamics in hemophiliac patients infected with hepatitis C virus and human immunodeficiency virus: influence of antiretroviral therapy
Shouichi Yokozaki,Junki Takamatsu,Isao Nakano,Yoshiaki Katano,Hidenori Toyoda,Kazuhiko Hayashi,Tetsuo Hayakawa,Yoshihide Fukuda
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The long pentraxin PTX3 binds to apoptotic cells and regulates their clearance by antigen-presenting dendritic cells
Patrizia Rovere,Giuseppe Peri,Fausto Fazzini,Barbara Bottazzi,Andrea Doni,Attilio Bondanza,Valérie S. Zimmermann,Cecilia Garlanda,Umberto Fascio,Maria Grazia Sabbadini,Claudio Rugarli,Alberto Mantovani,Angelo A. Manfredi
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NEOPLASIA

Differential effects of CD30 activation in anaplastic large cell lymphoma and Hodgkin disease cells
Samy S. Mir,Bettina W. M. Richter,Colin S. Duckett
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Interferon α down-regulates telomerase reverse transcriptase and telomerase activity in human malignant and nonmalignant hematopoietic cells
Dawei Xu,Sven Erickson,Michael Szeps,Astrid Gruber,Olle Sangfelt,Stefan Einhorn,Pavel Pisa,Dan Grandér
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Nucleophosmin–anaplastic lymphoma kinase associated with anaplastic large-cell lymphoma activates the phosphatidylinositol 3-kinase/Akt antiapoptotic signaling pathway
Ren-Yuan Bai,Tao Ouyang,Cornelius Miething,Stephan W. Morris,Christian Peschel,Justus Duyster
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BAL is a novel risk-related gene in diffuse large B-cell lymphomas that enhances cellular migration
Ricardo C. T. Aguiar,Yoshihiro Yakushijin,Samir Kharbanda,Ravi Salgia,Jonathan A. Fletcher,Margaret A. Shipp
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PHAGOCYTES

An adherent condition is required for formation of multinuclear osteoclasts in the presence of macrophage colony-stimulating factor and receptor activator of nuclear factor κB ligand
Takeshi Miyamoto,Fumio Arai,Osamu Ohneda,Katsumasa Takagi,Dirk M. Anderson,Toshio Suda
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TRANSPLANTATION

Similar pattern of thymic-dependent T-cell reconstitution in infants with severe combined immunodeficiency after human leukocyte antigen (HLA)–identical and HLA-nonidentical stem cell transplantation
Susanna M. Müller,Thomas Kohn,Ansgar S. Schulz,Klaus-Michael Debatin,Wilhelm Friedrich
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Keratinocyte growth factor facilitates alloengraftment and ameliorates graft-versus-host disease in mice by a mechanism independent of repair of conditioning-induced tissue injury
Angela Panoskaltsis-Mortari,Patricia A. Taylor,Jeffrey S. Rubin,Aykut Uren,Lisbeth A. Welniak,William J. Murphy,Catherine L. Farrell,David L. Lacey,Bruce R. Blazar
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BRIEF REPORTS

Frequency and kinetics of polyclonal and clonal B cells in the peripheral blood of patients being treated for multiple myeloma
Brief Report
Thomas Rasmussen,Linda Jensen,Lone Honoré,Hans Erik Johnsen
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t(3;11) translocation in treatment-related acute myeloid leukemia fuses MLL with the GMPS (GUANOSINE 5′ MONOPHOSPHATE SYNTHETASE) gene
Brief Report
Linda D. Pegram,Maureen D. Megonigal,Beverly J. Lange,Peter C. Nowell,Janet D. Rowley,Eric F. Rappaport,Carolyn A. Felix
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Familial-skewed X-chromosome inactivation as a predisposing factor for late-onset X-linked sideroblastic anemia in carrier females
Brief Report
Mario Cazzola,Alison May,Gaetano Bergamaschi,Paola Cerani,Vittorio Rosti,David F. Bishop
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Abnormalities of primitive myeloid progenitor cells expressing granulocyte colony-stimulating factor receptor in patients with severe congenital neutropenia: Presented in part at the 41st Annual Meeting of the American Society of Hematology, New Orleans, LA, December 3-7, 1999.
Brief Report
Kazuhiro Nakamura,Masao Kobayashi,Nakao Konishi,Hiroshi Kawaguchi,Shin-ichiro Miyagawa,Takashi Sato,Hidemi Toyoda,Yoshihiro Komada,Seiji Kojima,Osamu Katoh,Kazuhiro Ueda
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A new mutation in the HNF4 binding region of the factor VII promoter in a patient with severe factor VII deficiency
Brief Report
Josephine A. Carew,Eleanor S. Pollak,Stanislaw Lopaciuk,Kenneth A. Bauer
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Unbalanced X-chromosome inactivation with a novel FVIII gene mutation resulting in severe hemophilia A in a female
Brief Report
Rémi Favier,Jean-Maurice Lavergne,Jean-Marc Costa,Claudine Caron,Claudine Mazurier,Michèle Viémont,Marc Delpech,Sophie Valleix
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