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Journal Articles

Validation of the Molecular International Prognostic Scoring System (IPSS-M) in Patients (Pts) with Myelodysplastic Syndromes/Neoplasms (MDS) Who Underwent Allogenic Stem Cell Transplantation (HSCT)

Tariq Kewan, Jan Philipp Bewersdorf, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Geoffrey L Uy, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Maria L Amaya, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Constantine Logothetis, Hunter Cochran, Ameera Rose, Gail J. Roboz, Eunice S. Wang, Benjamin Rolles, Amyah C. Harris, Rory M. Shallis, Zhuoer Xie, Eric Padron, Jaroslaw P. Maciejewski, David A Sallman, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 4980.
https://doi.org/10.1182/blood-2023-186578
Published: 2023
Journal Articles

Impact of Type of Hypomethylating Agent (HMA) Used on Outcomes of Patients (Pts) with Higher-Risk Myelodysplastic Syndromes/Neoplasms (HR-MDS) - a Large, Multicenter, Retrospective Analysis

Jan Philipp Bewersdorf, Tariq Kewan, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Geoffrey L Uy, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Christine M. McMahon, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Rahul Ramaswamy, Gail J. Roboz, Benjamin Rolles, Eunice S. Wang, Amyah C. Harris, Maria L Amaya, Hayley Hawkins, Justin Grenet, Carmelo Gurnari, Rory M. Shallis, Zhuoer Xie, Jaroslaw P. Maciejewski, David A Sallman, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 4613.
https://doi.org/10.1182/blood-2023-178728
Published: 2023
Journal Articles

Novel Bone Marrow/HSC-Targeted, Megakaryocyte-Derived Extracellular Vesicle Delivery Modality for In Vivo Gene Therapy

Laura R Goldberg, Qiuyan W Ma, Navdeep Malik, Daniel Bode, Samik Das, Will Thompson, Jenna C Harris, Joseph R Inigo, Pragati Jain, Emily S Day, David M Raiser, Sedattin S Ozturk, Eleftherios T Papoutsakis, Iain R Thompson, Jonathan N. Thon
Journal: Blood
Blood (2023) 142 (Supplement 1): 2253.
https://doi.org/10.1182/blood-2023-179450
Published: 2023
Journal Articles

Validation of the Molecular International Prognostic Scoring System (IPSS-M) in Patients (Pts) with Myelodysplastic Syndromes/Neoplasms (MDS) Who Were Treated with Hypomethylating Agents (HMA)

Tariq Kewan, Jan Philipp Bewersdorf, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Maria L Amaya, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Constantine Logothetis, Rahul Ramaswamy, Ameera Rose, Gail J. Roboz, Benjamin Rolles, Eunice S. Wang, Amyah C. Harris, Rory M. Shallis, Zhuoer Xie, Eric Padron, Jaroslaw P. Maciejewski, David A Sallman, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 3240.
https://doi.org/10.1182/blood-2023-186340
Published: 2023
Journal Articles

Changes in White Blood Cell Counts Early during Treatment of Acute Leukemia Using Differentiating Chemotherapies

Amyah C. Harris, Christopher S. Bell, Gabriela S. Hobbs, Hanno Hock, Philip C. Amrein, Rupa Narayan, Amir T. Fathi, Andrew M. Brunner
Journal: Blood
Blood (2023) 142 (Supplement 1): 1486.
https://doi.org/10.1182/blood-2023-187367
Published: 2023
Journal Articles

Evaluation of the Molecular International Prognostic Scoring System (IPSS-M) in Patients (Pts) with Myelodysplastic Syndromes/Neoplasms (MDS) with Missing Molecular Data

Tariq Kewan, Jan Philipp Bewersdorf, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Maria L Amaya, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Constantine Logothetis, Hunter Cochran, Abhay Singh, Gail J. Roboz, Benjamin Rolles, Eunice S. Wang, Amyah C. Harris, Rory M. Shallis, Zhuoer Xie, Eric Padron, David A Sallman, Jaroslaw P. Maciejewski, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 4607.
https://doi.org/10.1182/blood-2023-187053
Published: 2023
Journal Articles

Clinical Implications of TP53 Mutations/Allelic State in Patients (Pts) with Myelodysplastic Syndromes/Neoplasms (MDS) Treated with Hypomethylating Agents (HMA)- a Multicenter, Retrospective Analysis from the Validate Database

Tariq Kewan, Jan Philipp Bewersdorf, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Maria L Amaya, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Hunter Cochran, Rahul Ramaswamy, Abhay Singh, Gail J. Roboz, Benjamin Rolles, Eunice S. Wang, Amyah C. Harris, Rory M. Shallis, Zhuoer Xie, Eric Padron, Jaroslaw P. Maciejewski, Matteo Giovanni Della Porta, Rami S. Komrokji, David A Sallman, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 1002.
https://doi.org/10.1182/blood-2023-186875
Published: 2023
Journal Articles

High Risk of GvHD in Children Transplanted for Refractory Cytopenia of Childhood: Importance of Sufficient Exposure to Anti-Thymocyte Globulin

Eva Koopman-Coenen, Joyce Meesters-Ensing, Stefan Nierkens, Ireen J. Kal, Konradin F. Müskens, Birgitta Versluijs, Caroline A. Lindemans, Andrew C. Harris, Marc Bierings, Rick Admiraal, Mirjam E. Belderbos
Journal: Blood
Blood (2023) 142 (Supplement 1): 6997.
https://doi.org/10.1182/blood-2023-181662
Published: 2023
Journal Articles

Validation of the Composite Complete Response (cCR) Definitions in the International Working Group (IWG) 2023 Criteria in Patients (Pts) with Higher-Risk Myelodysplastic Syndromes/Neoplasms (HR-MDS) Treated with Hypomethylating Agents (HMA) - a Large, Multicenter, Retrospective Analysis from the Validate Database

Jan Philipp Bewersdorf, Tariq Kewan, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Geoffrey L Uy, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Christine M. McMahon, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Constantine Logothetis, Gail J. Roboz, Benjamin Rolles, Eunice S. Wang, Amyah C. Harris, Maria L Amaya, Hayley Hawkins, Justin Grenet, Rory M. Shallis, Zhuoer Xie, Jaroslaw P. Maciejewski, David A Sallman, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 324.
https://doi.org/10.1182/blood-2023-180299
Published: 2023
Journal Articles

Higher abatacept exposure after transplant decreases acute GVHD risk without increasing adverse events

Clinical Trials & Observations
Takuto Takahashi, Mahmoud Al-Kofahi, Mutaz Jaber, Brandi Bratrude, Kayla Betz, Yvonne Suessmuth, Alison Yu, Donna S. Neuberg, Sung W. Choi, Jeffrey Davis, Christine Duncan, Roger Giller, Michael Grimley, Andrew C. Harris, David Jacobsohn, Nahal Lalefar, Nosha Farhadfar, Michael A. Pulsipher, Shalini Shenoy, Aleksandra Petrovic, Kirk R. Schultz, Gregory A. Yanik, Bruce R. Blazar, John T. Horan, Benjamin Watkins, Amelia Langston, Muna Qayed, Leslie S. Kean
Journal: Blood
Blood (2023) 142 (8): 700–710.
https://doi.org/10.1182/blood.2023020035
Published: 2023
Includes: Supplemental data
Journal Articles

Metabolomic identification of α-ketoglutaric acid elevation in pediatric chronic graft-versus-host disease

Clinical Trials & Observations
Divya Subburaj, Bernard Ng, Amina Kariminia, Sayeh Abdossamadi, Madeline Lauener, Eneida R. Nemecek, Jacob Rozmus, Sandhya Kharbanda, Carrie L. Kitko, Victor A. Lewis, Tal Schechter-Finklestein, David A. Jacobsohn, Andrew C. Harris, Michael A. Pulsipher, Henrique Bittencourt, Sung Won Choi, Emi H. Caywood, Kimberly A. Kasow, Monica Bhatia, Benjamin R. Oshrine, Donald Coulter, Joseph H. Chewning, Michael Joyce, Anna B. Pawlowska, Gail C. Megason, Anita Lawitschka, Elena Ostroumov, Ramon Klein Geltink, Geoffrey D. E. Cuvelier, Kirk R. Schultz
Journal: Blood
Blood (2022) 139 (2): 287–299.
https://doi.org/10.1182/blood.2021013244
Published: 2022
Includes: Supplemental data
Journal Articles

Naïve Helper T-Cell and Regulatory T- and NK-Cell Subsets Are Associated with Pediatric Chronic Graft-Versus-Host Disease: Results of the ABLE / PBMTC 1202 Study

Geoff D.E. Cuvelier, MD, Amina Kariminia, PhD, Eneida R. Nemecek, MDMBA,MSc, Carrie Kitko, MD, Justin T. Wahlstrom, MD, Andrew C Harris, MD, Henrique Bittencourt, MD PhD, Victor A. Lewis, MD, Michael A Pulsipher, MD, Tal Schechter-Finkelstein, MD, Sung W. Choi, MD, Emi Caywood, MD, Monica Bhatia, MD, Kimberly A. Kasow, DO, David Jacobsohn, MD, Benjamin Oshrine, MD, Sonali Chaudhury, MD, Joseph H. Chewning, MD, Flower Allyson, MD, Don W. Coulter, MD, Michael J. Joyce, MD, Sureyya Savasan, MD, Anna Pawlowska, MD, Gail Megason, MD, David Mitchell, MD, Alexandra Cheerva, MD, Anita Lawitschka, MD, Bernard Ng, PhD, Kirk R. Schultz, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11–12.
https://doi.org/10.1182/blood-2020-139031
Published: 2020
Journal Articles

Immune profile differences between chronic GVHD and late acute GVHD: results of the ABLE/PBMTC 1202 studies

Clinical Trials & Observations
Kirk R. Schultz, Amina Kariminia, Bernard Ng, Sayeh Abdossamadi, Madeline Lauener, Eneida R. Nemecek, Justin T. Wahlstrom, Carrie L. Kitko, Victor A. Lewis, Tal Schechter, David A. Jacobsohn, Andrew C. Harris, Michael A. Pulsipher, Henrique Bittencourt, Sung Won Choi, Emi H. Caywood, Kimberly A. Kasow, Monica Bhatia, Benjamin R. Oshrine, Allyson Flower, Sonali Chaudhury, Donald Coulter, Joseph H. Chewning, Michael Joyce, Sureyya Savasan, Anna B. Pawlowska, Gail C. Megason, David Mitchell, Alexandra C. Cheerva, Anita Lawitschka, Shima Azadpour, Elena Ostroumov, Peter Subrt, Anat Halevy, Sara Mostafavi, Geoffrey D. E. Cuvelier
Journal: Blood
Blood (2020) 135 (15): 1287–1298.
https://doi.org/10.1182/blood.2019003186
Published: 2020
Includes: Supplemental data
Journal Articles

Tisagenlecleucel Chimeric Antigen Receptor (CAR) T-Cell Therapy for Relapsed/Refractory Children and Young Adults with Acute Lymphoblastic Leukemia (ALL): Real World Experience from the Center for International Blood and Marrow Transplant Research (CIBMTR) and Cellular Therapy (CT) Registry

Stephan Grupp, MD PhD, Zhen-Huan Hu, MPH, Yiyun Zhang, PhD, Amy Keating, MD, Michael A. Pulsipher, MD, Christine Philips, Steven P. Margossian, MD PhD, Joseph Rosenthal, MD MS, Dana Salzberg, MD, Deborah E. Schiff, MD, Gregory Yanik, MD, Kevin J. Curran, MD, Andrew C. Harris, MD, Peiman Hematti, MD, Sarah Nikiforow, MD PhD, Patricia Steinert, PhD, Lan Yi, PhD, Raghav Chawla, MD PhD, Mary M. Horowitz, Eric Bleickardt, MD, Marcelo C. Pasquini, MDMS
Journal: Blood
Blood (2019) 134 (Supplement_1): 2619.
https://doi.org/10.1182/blood-2019-129279
Published: 2019
Journal Articles

A Phase 2 Trial of Inotuzumab Ozogamicin (InO) in Children and Young Adults with Relapsed or Refractory (R/R) CD22+ B-Acute Lymphoblastic Leukemia (B-ALL): Results from Children's Oncology Group Protocol AALL1621

Maureen M O'Brien, MD, Lingyun Ji, PhD, Nirali N. Shah, MD, Susan R. Rheingold, MD, Deepa Bhojwani, MD, Joanna S. Yi, MD, Constance M. Yuan, MD PhD, Andrew C Harris, MD, Patrick A. Brown, MD, Michael J. Borowitz, MD PhD, Olga Militano, PharmD, Meenakshi Devidas, PhD, Elizabeth A. Raetz, MD, Lia Gore, MD, Mignon L. Loh, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 741.
https://doi.org/10.1182/blood-2019-128977
Published: 2019
Journal Articles

Benefits and challenges with diagnosing chronic and late acute GVHD in children using the NIH consensus criteria

CME
Geoffrey D. E. Cuvelier, Eneida R. Nemecek, Justin T. Wahlstrom, Carrie L. Kitko, Victor A. Lewis, Tal Schechter, David A. Jacobsohn, Andrew C. Harris, Michael A. Pulsipher, Henrique Bittencourt, Sung Won Choi, Emi H. Caywood, Kimberly A. Kasow, Monica Bhatia, Benjamin R. Oshrine, Allyson Flower, Sonali Chaudhury, Donald Coulter, Joseph H. Chewning, Michael Joyce, Süreyya Savaşan, Anna B. Pawlowska, Gail C. Megason, David Mitchell, Alexandra C. Cheerva, Anita Lawitschka, Lori J. West, Bo Pan, Yazid N. Al Hamarneh, Anat Halevy, Kirk R. Schultz
Journal: Blood
Blood (2019) 134 (3): 304–316.
https://doi.org/10.1182/blood.2019000216
Published: 2019
Includes: Supplemental data
Journal Articles

MAGIC biomarkers predict long-term outcomes for steroid-resistant acute GVHD

CME Clinical Trials & Observations
Hannah Major-Monfried, Anne S. Renteria, Attaphol Pawarode, Pavan Reddy, Francis Ayuk, Ernst Holler, Yvonne A. Efebera, William J. Hogan, Matthias Wölfl, Muna Qayed, Elizabeth O. Hexner, Kitsada Wudhikarn, Rainer Ordemann, Rachel Young, Jay Shah, Matthew J. Hartwell, Mohammed S. Chaudhry, Mina Aziz, Aaron Etra, Gregory A. Yanik, Nicolaus Kröger, Daniela Weber, Yi-Bin Chen, Ryotaro Nakamura, Wolf Rösler, Carrie L. Kitko, Andrew C. Harris, Michael Pulsipher, Ran Reshef, Steven Kowalyk, George Morales, Ivan Torres, Umut Özbek, James L. M. Ferrara, John E. Levine
Journal: Blood
Blood (2018) 131 (25): 2846–2855.
https://doi.org/10.1182/blood-2018-01-822957
Published: 2018
Includes: Supplemental data
Journal Articles

CTL019 Therapy Appears Safe and Effective in Pediatric Patients with Down Syndrome with Relapsed/ Refractory (r/r) Acute Lymphoblastic Leukemia

Theodore W Laetsch, MD, Shannon L Maude, MD PhD, Stephan A Grupp, MD PhD, Michael W Boyer, MD, Andrew C Harris, MD, Muna Qayed, MDMSc, Christine L Phillips, MD, Michael A Pulsipher, MD, Henrique Bittencourt, MD PhD, Patricia A Wood, MD PhD, Karen Thudium Mueller, PharmD,MSc, Yanqui Weng, PhD, Carl H June, MD, Bruce L Levine, PhD, Hidefumi Hiramatsu, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1280.
https://doi.org/10.1182/blood.V130.Suppl_1.1280.1280
Published: 2017
Journal Articles

T Cell Costimulation Blockade with Abatacept Nearly Eliminates Early Severe Acute Graft Versus Host Disease after HLA-Mismatched (7/8 HLA Matched) Unrelated Donor Transplant, with a Favorable Impact on Disease-Free and Overall Survival

Ben Watkins, MD, Muna Qayed, MDMSc, Brandi Bratrude, Kayla Betz, Melanie Brown, BS, James Rhodes, Shauna Sinclair, Yvonne Suessmuth, Alison Yu, PhD, Kyle Hebert, Marcelo C. Pasquini, MDMS, Sung W. Choi, MD MS, Jeffrey Davis, Christine Duncan, MD MSc, Roger Giller, MD, Michael Grimley, MD, Andrew C Harris, MD, David A. Jacobsohn, MD, Nahal Lalefar, Maxim Norkin, MD, Michael A Pulsipher, MD, Shalini Shenoy, MD, Bruce Blazar, MD, Amelia Langston, MD, John T Horan, MD, Leslie Kean, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 212.
https://doi.org/10.1182/blood.V130.Suppl_1.212.212
Published: 2017
Journal Articles

An Early Biomarker Algorithm Predicts Lethal Graft-Versus-Host Disease and Survival after Allogeneic Hematopoietic Cell Transplantation

Matthew J Hartwell, BA, Umut Ozbek, PhD, Ernst Holler, MD, Anne S. Renteria, MD, Pavan R. Reddy, MD, Mina Aziz, William J Hogan, MD, Francis A Ayuk, MD, Yvonne A Efebera, MD MPH, Elizabeth O. Hexner, MD, Udomsak Bunworasate, MD, Muna Qayed, MD MSc, Rainer Ordemann, MD, Matthias Wolfl, MD, Stephan Mielke, MD, Attaphol Pawarode, MD, Yi-Bin Chen, MD, Steven M. Devine, MD, Andrew C. Harris, MD, Madan H. Jagasia, MD, Carrie L Kitko, MD, Mark R Litzow, MD, Nicolaus Kroeger, MD, Franco Locatelli, MD, Ryotaro Nakamura, MD, Ran Reshef, MD, Wolf Roesler, MD, Daniela Weber, MD, Kitsada Wudhikarn, MD, Gregory A Yanik, MD, John E. Levine, MD, M.S., James L.M. Ferrara, MD
Journal: Blood
Blood (2016) 128 (22): 509.
https://doi.org/10.1182/blood.V128.22.509.509
Published: 2016