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INSIDE BLOOD

VEGF: is it just an inducer of heme oxygenase-1 expression?

Miguel P. Soares

View Articletitled, VEGF: is it just an inducer of heme oxygenase-1 expression?

Gutted adenoviral vectors in hemophilia A

Katherine A. High

View Articletitled, Gutted adenoviral vectors in hemophilia A

Helicobacter pylori and ITP: many questions, few answers

Keith R. McCrae

View Articletitled, Helicobacter pylori and ITP: many questions, few answers

Activated Fps/Fes to the rescue

Mervin Yoder, Jr

View Articletitled, Activated Fps/Fes to the rescue

von Willebrand factor: polymorphism predicts prompt polypeptide proteolysis

José A. López

View Articletitled, von Willebrand factor: polymorphism predicts prompt polypeptide proteolysis

NF-κB activation in atherosclerosis: a friend or a foe?

Ziad Mallat,Alain Tedgui

View Articletitled, NF-κB activation in atherosclerosis: a friend or a foe?

Memory depending on an intimate relationship

Yutaka Tagaya

View Articletitled, Memory depending on an intimate relationship

HIF: a paradigm of biologic versatility

H. Franklin Bunn

View Articletitled, HIF: a paradigm of biologic versatility

CD4⁺CD25⁺ T cells: friends or foes?

Scott R. Solomon

View Articletitled, CD4+CD25+ T cells: friends or foes?

No donor? Then create one!

Richard E. Harris

View Articletitled, No donor? Then create one!

BLOOD WORK

Acute monocytic leukemia

View Articletitled, Acute monocytic leukemia

PLENARY PAPERS

Bifunctional role for VEGF-induced heme oxygenase-1 in vivo: induction of angiogenesis and inhibition of leukocytic infiltration

Benedetta Bussolati,Asif Ahmed,Helen Pemberton,R. Clive Landis,Francesco Di Carlo,Dorian O. Haskard,Justin C. Mason

View Articletitled, Bifunctional role for VEGF-induced heme oxygenase-1 in vivo: induction of angiogenesis and inhibition of leukocytic infiltration

REVIEW ARTICLES

Graft-versus-leukemia reactions in allogeneic chimeras

Hans-Jochem Kolb,Christoph Schmid,A. John Barrett,Dolores J. Schendel

View Articletitled, Graft-versus-leukemia reactions in allogeneic chimeras

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Rituximab as adjuvant to high-dose therapy and autologous hematopoietic cell transplantation for aggressive non-Hodgkin lymphoma
Clinical Trials & Observations

Steven M. Horwitz,Robert S. Negrin,Karl G. Blume,Sheila Breslin,Monic J. Stuart,Keith E. Stockerl-Goldstein,Laura J. Johnston,Ruby M. Wong,Judith A. Shizuru,Sandra J. Horning

View Articletitled, Rituximab as adjuvant to high-dose therapy and autologous hematopoietic cell transplantation for aggressive non-Hodgkin lymphoma

Clofarabine, a novel nucleoside analog, is active in pediatric patients with advanced leukemia
Clinical Trials & Observations

Sima Jeha,Varsha Gandhi,Ka Wah Chan,Lisa McDonald,Irma Ramirez,Renee Madden,Michael Rytting,Mark Brandt,Michael Keating,William Plunkett,Hagop Kantarjian

View Articletitled, Clofarabine, a novel nucleoside analog, is active in pediatric patients with advanced leukemia

Adoptive immunotherapy with donor lymphocyte infusions after allogeneic hematopoietic cell transplantation following nonmyeloablative conditioning
Clinical Trials & Observations

Wolfgang A. Bethge,Ute Hegenbart,Monic J. Stuart,Barry E. Storer,Michael B. Maris,Mary E. D. Flowers,David G. Maloney,Thomas Chauncey,Benedetto Bruno,Ed Agura,Stephen J. Forman,Karl G. Blume,Dietger Niederwieser,Rainer Storb,Brenda M. Sandmaier

View Articletitled, Adoptive immunotherapy with donor lymphocyte infusions after allogeneic hematopoietic cell transplantation following nonmyeloablative conditioning

GENE THERAPY

Transient in vivo selection of transduced peripheral blood cells using antifolate drug selection in rhesus macaques that received transplants with hematopoietic stem cells expressing dihydrofolate reductase vectors

Derek A. Persons,James A. Allay,Aylin Bonifacino,Taihe Lu,Brian Agricola,Mark E. Metzger,Robert E. Donahue,Cynthia E. Dunbar,Brian P. Sorrentino

View Articletitled, Transient in vivo selection of transduced peripheral blood cells using antifolate drug selection in rhesus macaques that received transplants with hematopoietic stem cells expressing dihydrofolate reductase vectors

Helper-dependent adenoviral vectors mediate therapeutic factor VIII expression for several months with minimal accompanying toxicity in a canine model of severe hemophilia A

Brian D. Brown,Chang Xin Shi,Sandra Powell,David Hurlbut,Frank L. Graham,David Lillicrap

View Articletitled, Helper-dependent adenoviral vectors mediate therapeutic factor VIII expression for several months with minimal accompanying toxicity in a canine model of severe hemophilia A

Highly efficient expression of transgenic proteins by naked DNA-transfected dendritic cells through terminal differentiation

Adriana T. Larregina,Adrian E. Morelli,Olga Tkacheva,Geza Erdos,Cara Donahue,Simon C. Watkins,Angus W. Thomson,Louis D. Falo, Jr

View Articletitled, Highly efficient expression of transgenic proteins by naked DNA-transfected dendritic cells through terminal differentiation

HEMATOPOIESIS

The phosphoserine-585–dependent pathway of the GM-CSF/IL-3/IL-5 receptors mediates hematopoietic cell survival through activation of NF-κB and induction of bcl-2

Mark A. Guthridge,Emma F. Barry,Fernando A. Felquer,Barbara J. McClure,Frank C. Stomski,Hayley Ramshaw,Angel F. Lopez

View Articletitled, The phosphoserine-585–dependent pathway of the GM-CSF/IL-3/IL-5 receptors mediates hematopoietic cell survival through activation of NF-κB and induction of bcl-2

C/EBPϵ interacts with retinoblastoma and E2F1 during granulopoiesis

Sigal Gery,Adrian F. Gombart,Yuen K. Fung,H. Phillip Koeffler

View Articletitled, C/EBPϵ interacts with retinoblastoma and E2F1 during granulopoiesis

A potential therapeutic role for small nonpeptidyl compounds that mimic human granulocyte colony-stimulating factor

Kouji Kusano,Shinji Ebara,Koichi Tachibana,Tadahiro Nishimura,Susumu Sato,Tomoaki Kuwaki,Tadayoshi Taniyama

View Articletitled, A potential therapeutic role for small nonpeptidyl compounds that mimic human granulocyte colony-stimulating factor

Overexpression of murine TSLP impairs lymphopoiesis and myelopoiesis

Mark J. Osborn,Patricia L. Ryan,Nicole Kirchhof,Angela Panoskaltsis-Mortari,Frank Mortari,Kim-Sue R. S. Tudor

View Articletitled, Overexpression of murine TSLP impairs lymphopoiesis and myelopoiesis

The in vitro production and characterization of neutrophils from embryonic stem cells

Jonathan G. Lieber,Saiphone Webb,Benjamin T. Suratt,Scott K. Young,Gary L. Johnson,Gordon M. Keller,G. Scott Worthen

View Articletitled, The in vitro production and characterization of neutrophils from embryonic stem cells

Development of both human connective tissue-type and mucosal-type mast cells in mice from hematopoietic stem cells with identical distribution pattern to human body

Naotomo Kambe,Hidefumi Hiramatsu,Mika Shimonaka,Hisanori Fujino,Ryuta Nishikomori,Toshio Heike,Mamoru Ito,Kimio Kobayashi,Yoshito Ueyama,Norihisa Matsuyoshi,Yoshiki Miyachi,Tatsutoshi Nakahata

View Articletitled, Development of both human connective tissue-type and mucosal-type mast cells in mice from hematopoietic stem cells with identical distribution pattern to human body

Gene microarray analysis reveals interleukin-5–dependent transcriptional targets in mouse bone marrow

Jonas Byström,Thomas A. Wynn,Joseph B. Domachowske,Helene F. Rosenberg

View Articletitled, Gene microarray analysis reveals interleukin-5–dependent transcriptional targets in mouse bone marrow

Single administration of stem cell factor, FLT-3 ligand, megakaryocyte growth and development factor, and interleukin-3 in combination soon after irradiation prevents nonhuman primates from myelosuppression: long-term follow-up of hematopoiesis

Michel Drouet,Frédéric Mourcin,Nancy Grenier,Valérie Leroux,Josianne Denis,Jean-François Mayol,Philippe Thullier,Jean-Jacques Lataillade,Francis Herodin

View Articletitled, Single administration of stem cell factor, FLT-3 ligand, megakaryocyte growth and development factor, and interleukin-3 in combination soon after irradiation prevents nonhuman primates from myelosuppression: long-term follow-up of hematopoiesis

Haploinsufficiency of Runx1 results in the acceleration of mesodermal development and hemangioblast specification upon in vitro differentiation of ES cells
Brief Report

Georges Lacaud,Valerie Kouskoff,Anne Trumble,Staci Schwantz,Gordon Keller

View Articletitled, Haploinsufficiency of Runx1 results in the acceleration of mesodermal development and hemangioblast specification upon in vitro differentiation of ES cells

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Does Helicobater pylori initiate or perpetuate immune thrombocytopenic purpura?
Clinical Trials & Observations

Marc Michel,Nichola Cooper,Christelle Jean,Christine Frissora,James B. Bussel

View Articletitled, Does Helicobater pylori initiate or perpetuate immune thrombocytopenic purpura?

In vitro and in vivo effects of tPA and PAI-1 on blood vessel tone

Taher Nassar,Sa'ed Akkawi,Ahuva Shina,Abdullah Haj-Yehia,Khalil Bdeir,Mark Tarshis,Samuel N. Heyman,Abd Al-Roof Higazi

View Articletitled, In vitro and in vivo effects of tPA and PAI-1 on blood vessel tone

Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody

Peter A. Smethurst,Lotta Joutsi-Korhonen,Marie N. O'Connor,Erica Wilson,Nicola S. Jennings,Stephen F. Garner,Yanjun Zhang,C. Graham Knight,Timothy R. Dafforn,Ashley Buckle,Martin J. W. IJsseldijk,Philip G. de Groot,Nicholas A. Watkins,Richard W. Farndale,Willem H. Ouwehand

View Articletitled, Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody

Activated Fps/Fes partially rescues the in vivo developmental potential of Flk1-deficient vascular progenitor cells

Jody J. Haigh,Masatsugu Ema,Katharina Haigh,Marina Gertsenstein,Peter Greer,Janet Rossant,Andras Nagy,Erwin F. Wagner

View Articletitled, Activated Fps/Fes partially rescues the in vivo developmental potential of Flk1-deficient vascular progenitor cells

Supplemental data

Erythropoietin regulates endothelial progenitor cells

Ferdinand H. Bahlmann,Kirsten de Groot,Jens-Michael Spandau,Aimee L. Landry,Barbara Hertel,Thorsten Duckert,Sascha M. Boehm,Jan Menne,Hermann Haller,Danilo Fliser

View Articletitled, Erythropoietin regulates endothelial progenitor cells

Effect of second- and third-generation oral contraceptives on the protein C system in the absence or presence of the factor V_Leiden mutation: a randomized trial
Clinical Trials & Observations

Jeanet M. Kemmeren,Ale Algra,Joost C. M. Meijers,Guido Tans,Bonno N. Bouma,Joyce Curvers,Jan Rosing,Diederick E. Grobbee

View Articletitled, Effect of second- and third-generation oral contraceptives on the protein C system in the absence or presence of the factor VLeiden mutation: a randomized trial

Supplemental data

Hematopoietic NF-κB1 deficiency results in small atherosclerotic lesions with an inflammatory phenotype

Edwin Kanters,Marion J.J. Gijbels,Ingeborg van der Made,Monique N. Vergouwe,Peter Heeringa,Georg Kraal,Marten H. Hofker,Menno P. J. de Winther

View Articletitled, Hematopoietic NF-κB1 deficiency results in small atherosclerotic lesions with an inflammatory phenotype

An amino acid polymorphism in von Willebrand factor correlates with increased susceptibility to proteolysis by ADAMTS13

Derrick John Bowen,Peter William Collins

View Articletitled, An amino acid polymorphism in von Willebrand factor correlates with increased susceptibility to proteolysis by ADAMTS13

Association of CBFA2 mutation with decreased platelet PKC-θ and impaired receptor-mediated activation of GPIIb-IIIa and pleckstrin phosphorylation: proteins regulated by CBFA2 play a role in GPIIb-IIIa activation

Liansheng Sun,Guangfen Mao,A. Koneti Rao

View Articletitled, Association of CBFA2 mutation with decreased platelet PKC-θ and impaired receptor-mediated activation of GPIIb-IIIa and pleckstrin phosphorylation: proteins regulated by CBFA2 play a role in GPIIb-IIIa activation

Vascular endothelial growth factor (VEGF) induces rapid prourokinase (pro-uPA) activation on the surface of endothelial cells

Gerald W. Prager,Johannes M. Breuss,Stefan Steurer,Judit Mihaly,Bernd R. Binder

View Articletitled, Vascular endothelial growth factor (VEGF) induces rapid prourokinase (pro-uPA) activation on the surface of endothelial cells

Supplemental data

The variable number of tandem repeat polymorphism of platelet glycoprotein Ibα and risk of coronary heart disease
Clinical Trials & Observations Brief Report

Vahid Afshar-Kharghan,Nevenka Matijevic-Aleksic,Chul Ahn,Eric Boerwinkle,Kenneth K. Wu,José A. López

View Articletitled, The variable number of tandem repeat polymorphism of platelet glycoprotein Ibα and risk of coronary heart disease

Supplemental data

IMMUNOBIOLOGY

Skewed representation of functionally distinct populations of virus-specific CD4 T cells in HIV-1–infected subjects with progressive disease: changes after antiretroviral therapy
Clinical Trials & Observations

Alexandre Harari,Stéphanie Petitpierre,Florence Vallelian,Giuseppe Pantaleo

View Articletitled, Skewed representation of functionally distinct populations of virus-specific CD4 T cells in HIV-1–infected subjects with progressive disease: changes after antiretroviral therapy

Elevated interleukin-7 levels not sufficient to maintain T-cell homeostasis during simian immunodeficiency virus–induced disease progression

Alagarraju Muthukumar,Aneta Wozniakowski,Marie-Claire Gauduin,Mirko Paiardini,Harold M. McClure,R. Paul Johnson,Guido Silvestri,Donald L. Sodora

View Articletitled, Elevated interleukin-7 levels not sufficient to maintain T-cell homeostasis during simian immunodeficiency virus–induced disease progression

IFN-α promotes the rapid differentiation of monocytes from patients with chronic myeloid leukemia into activated dendritic cells tuned to undergo full maturation after LPS treatment

Lucia Gabriele,Paola Borghi,Carmela Rozera,Paola Sestili,Mauro Andreotti,Anna Guarini,Enrico Montefusco,Robert Foà,Filippo Belardelli

View Articletitled, IFN-α promotes the rapid differentiation of monocytes from patients with chronic myeloid leukemia into activated dendritic cells tuned to undergo full maturation after LPS treatment

Transregulation of memory CD8 T-cell proliferation by IL-15Rα⁺ bone marrow–derived cells

Kimberly S. Schluns,Kimberly D. Klonowski,Leo Lefrançois

View Articletitled, Transregulation of memory CD8 T-cell proliferation by IL-15Rα+ bone marrow–derived cells

The MHC class II transcriptional activator (CIITA) inhibits HTLV-2 viral replication by blocking the function of the viral transactivator Tax-2

Claudio Casoli,Andrea De Lerma Barbaro,Elisabetta Pilotti,Umberto Bertazzoni,Giovanna Tosi,Roberto S. Accolla

View Articletitled, The MHC class II transcriptional activator (CIITA) inhibits HTLV-2 viral replication by blocking the function of the viral transactivator Tax-2

Association of CD26 with CD45RA outside lipid rafts attenuates cord blood T-cell activation

Seiji Kobayashi,Kei Ohnuma,Masahiko Uchiyama,Kouichi Iino,Satoshi Iwata,Nam H. Dang,Chikao Morimoto

View Articletitled, Association of CD26 with CD45RA outside lipid rafts attenuates cord blood T-cell activation

Fiber-modified adenoviruses generate subgroup cross-reactive, adenovirus-specific cytotoxic T lymphocytes for therapeutic applications

Ann M. Leen,Uluhan Sili,Barbara Savoldo,Alan M. Jewell,Pedro A. Piedra,Malcolm K. Brenner,Cliona M. Rooney

View Articletitled, Fiber-modified adenoviruses generate subgroup cross-reactive, adenovirus-specific cytotoxic T lymphocytes for therapeutic applications

T-cell homeostasis in humans with thymic hypoplasia due to chromosome 22q11.2 deletion syndrome

Lisa M. Piliero,Amy N. Sanford,Donna M. McDonald-McGinn,Elaine H. Zackai,Kathleen E. Sullivan

View Articletitled, T-cell homeostasis in humans with thymic hypoplasia due to chromosome 22q11.2 deletion syndrome

Presence of functional dendritic cells in patients chronically infected with hepatitis C virus
Clinical Trials & Observations Brief Report

Randy S. Longman,Andrew H. Talal,Ira M. Jacobson,Matthew L. Albert,Charles M. Rice

View Articletitled, Presence of functional dendritic cells in patients chronically infected with hepatitis C virus

Supplemental data

Blood plasmacytoid dendritic cell responses to CpG oligodeoxynucleotides are impaired in human newborns
Brief Report

Dominique De Wit,Véronique Olislagers,Stanislas Goriely,Françoise Vermeulen,Hermann Wagner,Michel Goldman,Fabienne Willems

View Articletitled, Blood plasmacytoid dendritic cell responses to CpG oligodeoxynucleotides are impaired in human newborns

LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rap1 activation and impaired stabilization of integrin bonds
Brief Report

Tatsuo Kinashi,Memet Aker,Maya Sokolovsky-Eisenberg,Valentin Grabovsky,Chisato Tanaka,Revital Shamri,Sara Feigelson,Amos Etzioni,Ronen Alon

View Articletitled, LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rap1 activation and impaired stabilization of integrin bonds

NEOPLASIA

A multivalent bcr-abl fusion peptide vaccination trial in patients with chronic myeloid leukemia
Clinical Trials & Observations

Kathleen Cathcart,Javier Pinilla-Ibarz,Tatyana Korontsvit,Joseph Schwartz,Victoriya Zakhaleva,Esperanza B. Papadopoulos,David A. Scheinberg

View Articletitled, A multivalent bcr-abl fusion peptide vaccination trial in patients with chronic myeloid leukemia

Gene expression patterns associated with recurrent chromosomal translocations in acute lymphoblastic leukemia

Bernard M. Fine,Martin Stanulla,Martin Schrappe,Minh Ho,Susanne Viehmann,Jochen Harbott,Linda M. Boxer

View Articletitled, Gene expression patterns associated with recurrent chromosomal translocations in acute lymphoblastic leukemia

Supplemental data

Lymphodepletion in the Apc^Min/+ mouse model of intestinal tumorigenesis

P. Louise Coletta,Albrecht M. Müller,Elena A. Jones,Bettina Mühl,Sarah Holwell,Deborah Clarke,Josephine L. Meade,Graham P. Cook,Gillian Hawcroft,Frederique Ponchel,Wai K. Lam,Ken A. MacLennan,Mark A. Hull,Constanze Bonifer,Alexander F. Markham

View Articletitled, Lymphodepletion in the ApcMin/+ mouse model of intestinal tumorigenesis

CD44: a new means to inhibit acute myeloid leukemia cell proliferation via p27^Kip1

Zeineb Gadhoum,Marie-Pierre Leibovitch,Junyuan Qi,Dominique Dumenil,Laetitia Durand,Serge Leibovitch,Florence Smadja-Joffe

View Articletitled, CD44: a new means to inhibit acute myeloid leukemia cell proliferation via p27Kip1

The effect of human tissue factor pathway inhibitor-2 on the growth and metastasis of fibrosarcoma tumors in athymic mice

Hitendra Singh Chand,Xin Du,Duan Ma,Hector David Inzunza,Shintaro Kamei,Donald Foster,Steven Brodie,Walter Kisiel

View Articletitled, The effect of human tissue factor pathway inhibitor-2 on the growth and metastasis of fibrosarcoma tumors in athymic mice

17-Allylamino-17-demethoxygeldanamycin (17-AAG) is effective in down-regulating mutated, constitutively activated KIT protein in human mast cells

Gerard Fumo,Cem Akin,Dean D. Metcalfe,Len Neckers

View Articletitled, 17-Allylamino-17-demethoxygeldanamycin (17-AAG) is effective in down-regulating mutated, constitutively activated KIT protein in human mast cells

FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy
Clinical Trials & Observations Brief Report

Takeshi Taketani,Tomohiko Taki,Kanji Sugita,Yoshiyuki Furuichi,Eiichi Ishii,Ryoji Hanada,Masahiro Tsuchida,Kenichi Sugita,Kohmei Ida,Yasuhide Hayashi

View Articletitled, FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy

PHAGOCYTES

High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis
Clinical Trials & Observations

Kanji Uchida,Koh Nakata,Bruce C. Trapnell,Takahiro Terakawa,Emi Hamano,Ayako Mikami,Ikumi Matsushita,John F. Seymour,Masayoshi Oh-eda,Ikuo Ishige,Yoshinobu Eishi,Takayuki Kitamura,Yoshitsugu Yamada,Kazuo Hanaoka,Naoto Keicho

View Articletitled, High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis

Granzyme B and perforin: constitutive expression in human polymorphonuclear neutrophils

Christof Wagner,Christof Iking-Konert,Birgit Denefleh,Sabine Stegmaier,Friederike Hug,G. Maria Hänsch

View Articletitled, Granzyme B and perforin: constitutive expression in human polymorphonuclear neutrophils

Unique CD18 mutations involving a deletion in the extracellular stalk region and a major truncation of the cytoplasmic domain in a patient with leukocyte adhesion deficiency type 1

Patricia Hixson,C. Wayne Smith,Susan B. Shurin,Michael F. Tosi

View Articletitled, Unique CD18 mutations involving a deletion in the extracellular stalk region and a major truncation of the cytoplasmic domain in a patient with leukocyte adhesion deficiency type 1

Incomplete restoration of colony-stimulating factor 1 (CSF-1) function in CSF-1–deficient Csf1^op/Csf1^op mice by transgenic expression of cell surface CSF-1

Xu-Ming Dai,Xiao-Hua Zong,Vonetta Sylvestre,E. Richard Stanley

View Articletitled, Incomplete restoration of colony-stimulating factor 1 (CSF-1) function in CSF-1–deficient Csf1op/Csf1op mice by transgenic expression of cell surface CSF-1

Hypoxic gene activation by lipopolysaccharide in macrophages: implication of hypoxia-inducible factor 1α

Caroline C. Blouin,Elisabeth L. Pagé,Guylaine M. Soucy,Darren E. Richard

View Articletitled, Hypoxic gene activation by lipopolysaccharide in macrophages: implication of hypoxia-inducible factor 1α

RED CELLS

Protein 4.2 is critical to CD47-membrane skeleton attachment in human red cells

Kris Noel Dahl,Ranganath Parthasarathy,Connie M. Westhoff,D. Mark Layton,Dennis E. Discher

View Articletitled, Protein 4.2 is critical to CD47-membrane skeleton attachment in human red cells

TRANSFUSION MEDICINE

Assessment of removal of human cytomegalovirus from blood components by leukocyte depletion filters using real-time quantitative PCR
Brief Report

Micaela Rios Visconti,Joanne Pennington,Stephen F. Garner,Jean-Pierre Allain,Lorna M. Williamson

View Articletitled, Assessment of removal of human cytomegalovirus from blood components by leukocyte depletion filters using real-time quantitative PCR

TRANSPLANTATION

CD25 expression on donor CD4⁺ or CD8⁺ T cells is associated with an increased risk for graft-versus-host disease after HLA-identical stem cell transplantation in humans
Clinical Trials & Observations

Marta Stanzani,Sergio L. R. Martins,Rima M. Saliba,Lisa S. St. John,Susan Bryan,Daniel Couriel,John McMannis,Richard E. Champlin,Jeffrey J. Molldrem,Krishna V. Komanduri

View Articletitled, CD25 expression on donor CD4+ or CD8+ T cells is associated with an increased risk for graft-versus-host disease after HLA-identical stem cell transplantation in humans

Successful hematopoietic stem cell transplantation for Fanconi anemia from an unaffected HLA-genotype–identical sibling selected using preimplantation genetic diagnosis
Clinical Trials & Observations

Satkiran S. Grewal,Jeffrey P. Kahn,Margaret L. MacMillan,Norma K. C. Ramsay,John E. Wagner

View Articletitled, Successful hematopoietic stem cell transplantation for Fanconi anemia from an unaffected HLA-genotype–identical sibling selected using preimplantation genetic diagnosis

Treatment of CD40 ligand deficiency by hematopoietic stem cell transplantation: a survey of the European experience, 1993-2002
Clinical Trials & Observations

View Articletitled, Treatment of CD40 ligand deficiency by hematopoietic stem cell transplantation: a survey of the European experience, 1993-2002

Ex vivo depletion of alloreactive cells based on CFSE dye dilution, activation antigen selection, and dendritic cell stimulation

Wayne R. Godfrey,Mark R. Krampf,Patricia A. Taylor,Bruce R. Blazar

View Articletitled, Ex vivo depletion of alloreactive cells based on CFSE dye dilution, activation antigen selection, and dendritic cell stimulation

Long-term expansion of transplantable human fetal liver hematopoietic stem cells
Brief Report

Pierre Rollini,Stefan Kaiser,Eveline Faes-van't Hull,Ursula Kapp,Serge Leyvraz

View Articletitled, Long-term expansion of transplantable human fetal liver hematopoietic stem cells

Donor immune reconstitution after liver–small bowel transplantation for multiple intestinal atresia with immunodeficiency
Clinical Trials & Observations Brief Report

Richard K. Gilroy,Peter F. Coccia,James E. Talmadge,Lori I. Hatcher,Samuel J. Pirruccello,Byers W. Shaw, Jr,Ronald J. Rubocki,Debra L. Sudan,Alan N. Langnas,Simon P. Horslen

View Articletitled, Donor immune reconstitution after liver–small bowel transplantation for multiple intestinal atresia with immunodeficiency

CORRESPONDENCE

¹⁸⁶Rhenium-labeled anti-CD20 antibody radioimmunotherapy followed by autologous peripheral blood stem cell transplantation in patients with relapsed or refractory non-Hodgkin lymphoma

Stefan Knop,Andreas Jakob,Lothar Kanz,Holger Hebart,Roland Bares,Bernhard Dohmen

View Articletitled, 186Rhenium-labeled anti-CD20 antibody radioimmunotherapy followed by autologous peripheral blood stem cell transplantation in patients with relapsed or refractory non-Hodgkin lymphoma

Granzyme A: an additional weapon of human polymorphonuclear neutrophils (PMNs) in innate immunity?

Kathrin Hochegger,Philipp Eller,Alexander R. Rosenkranz

View Articletitled, Granzyme A: an additional weapon of human polymorphonuclear neutrophils (PMNs) in innate immunity?

Issue Archive

Table of Contents

INSIDE BLOOD

BLOOD WORK

PLENARY PAPERS

REVIEW ARTICLES

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Rituximab as adjuvant to high-dose therapy and autologous hematopoietic cell transplantation for aggressive non-Hodgkin lymphoma Clinical Trials & Observations

Clofarabine, a novel nucleoside analog, is active in pediatric patients with advanced leukemia Clinical Trials & Observations

Adoptive immunotherapy with donor lymphocyte infusions after allogeneic hematopoietic cell transplantation following nonmyeloablative conditioning Clinical Trials & Observations

GENE THERAPY

HEMATOPOIESIS

Haploinsufficiency of Runx1 results in the acceleration of mesodermal development and hemangioblast specification upon in vitro differentiation of ES cells Brief Report

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Does Helicobater pylori initiate or perpetuate immune thrombocytopenic purpura? Clinical Trials & Observations

Effect of second- and third-generation oral contraceptives on the protein C system in the absence or presence of the factor VLeiden mutation: a randomized trial Clinical Trials & Observations

The variable number of tandem repeat polymorphism of platelet glycoprotein Ibα and risk of coronary heart disease Clinical Trials & Observations Brief Report

IMMUNOBIOLOGY

Skewed representation of functionally distinct populations of virus-specific CD4 T cells in HIV-1–infected subjects with progressive disease: changes after antiretroviral therapy Clinical Trials & Observations

Presence of functional dendritic cells in patients chronically infected with hepatitis C virus Clinical Trials & Observations Brief Report

Blood plasmacytoid dendritic cell responses to CpG oligodeoxynucleotides are impaired in human newborns Brief Report

LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rap1 activation and impaired stabilization of integrin bonds Brief Report

NEOPLASIA

A multivalent bcr-abl fusion peptide vaccination trial in patients with chronic myeloid leukemia Clinical Trials & Observations

FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy Clinical Trials & Observations Brief Report

PHAGOCYTES

High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis Clinical Trials & Observations

RED CELLS

TRANSFUSION MEDICINE

Assessment of removal of human cytomegalovirus from blood components by leukocyte depletion filters using real-time quantitative PCR Brief Report

TRANSPLANTATION

CD25 expression on donor CD4+ or CD8+ T cells is associated with an increased risk for graft-versus-host disease after HLA-identical stem cell transplantation in humans Clinical Trials & Observations

Successful hematopoietic stem cell transplantation for Fanconi anemia from an unaffected HLA-genotype–identical sibling selected using preimplantation genetic diagnosis Clinical Trials & Observations

Treatment of CD40 ligand deficiency by hematopoietic stem cell transplantation: a survey of the European experience, 1993-2002 Clinical Trials & Observations

Long-term expansion of transplantable human fetal liver hematopoietic stem cells Brief Report

Donor immune reconstitution after liver–small bowel transplantation for multiple intestinal atresia with immunodeficiency Clinical Trials & Observations Brief Report

CORRESPONDENCE

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American Society of Hematology

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Rituximab as adjuvant to high-dose therapy and autologous hematopoietic cell transplantation for aggressive non-Hodgkin lymphoma
Clinical Trials & Observations

Clofarabine, a novel nucleoside analog, is active in pediatric patients with advanced leukemia
Clinical Trials & Observations

Adoptive immunotherapy with donor lymphocyte infusions after allogeneic hematopoietic cell transplantation following nonmyeloablative conditioning
Clinical Trials & Observations

Haploinsufficiency of Runx1 results in the acceleration of mesodermal development and hemangioblast specification upon in vitro differentiation of ES cells
Brief Report

Does Helicobater pylori initiate or perpetuate immune thrombocytopenic purpura?
Clinical Trials & Observations

Effect of second- and third-generation oral contraceptives on the protein C system in the absence or presence of the factor V_Leiden mutation: a randomized trial
Clinical Trials & Observations

The variable number of tandem repeat polymorphism of platelet glycoprotein Ibα and risk of coronary heart disease
Clinical Trials & Observations Brief Report

Skewed representation of functionally distinct populations of virus-specific CD4 T cells in HIV-1–infected subjects with progressive disease: changes after antiretroviral therapy
Clinical Trials & Observations

Presence of functional dendritic cells in patients chronically infected with hepatitis C virus
Clinical Trials & Observations Brief Report

Blood plasmacytoid dendritic cell responses to CpG oligodeoxynucleotides are impaired in human newborns
Brief Report

LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rap1 activation and impaired stabilization of integrin bonds
Brief Report

A multivalent bcr-abl fusion peptide vaccination trial in patients with chronic myeloid leukemia
Clinical Trials & Observations

FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy
Clinical Trials & Observations Brief Report

High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis
Clinical Trials & Observations

Assessment of removal of human cytomegalovirus from blood components by leukocyte depletion filters using real-time quantitative PCR
Brief Report

CD25 expression on donor CD4⁺ or CD8⁺ T cells is associated with an increased risk for graft-versus-host disease after HLA-identical stem cell transplantation in humans
Clinical Trials & Observations

Successful hematopoietic stem cell transplantation for Fanconi anemia from an unaffected HLA-genotype–identical sibling selected using preimplantation genetic diagnosis
Clinical Trials & Observations

Treatment of CD40 ligand deficiency by hematopoietic stem cell transplantation: a survey of the European experience, 1993-2002
Clinical Trials & Observations

Long-term expansion of transplantable human fetal liver hematopoietic stem cells
Brief Report

Donor immune reconstitution after liver–small bowel transplantation for multiple intestinal atresia with immunodeficiency
Clinical Trials & Observations Brief Report