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Issue Archive

Volume 122, Issue 17
October 24 2013
Issue Cover

Table of Contents

INSIDE BLOOD

IMMUNOBIOLOGY
Found: a cellular activating ligand for NKp44
Sumati Rajagopalan,Eric O. Long
View Articletitled, Found: a cellular activating ligand for NKp44
INSIDE BLOOD
Gnawing at Metchnikoff’s paradigm
Ronald P. Taylor
View Articletitled, Gnawing at Metchnikoff’s paradigm
INSIDE BLOOD
HIV, EBV, and monoclonal gammopathy
Sham Mailankody,Ola Landgren
View Articletitled, HIV, EBV, and monoclonal gammopathy
MYELOID NEOPLASIA
Flying without a net in MDS
Mikkael A. Sekeres
View Articletitled, Flying without a net in MDS
MYELOID NEOPLASIA
Redirecting traffic using the XPO1 police
Sheela A. Abraham,Tessa L. Holyoake
View Articletitled, Redirecting traffic using the XPO1 police
RED CELLS, IRON, & ERYTHROPOIESIS
An open-and-shut case?
Narla Mohandas
View Articletitled, An open-and-shut case?
RED CELLS, IRON, & ERYTHROPOIESIS
Anti-hepcidin therapy for iron-restricted anemias
Elizabeta Nemeth
View Articletitled, Anti-hepcidin therapy for iron-restricted anemias

BLOOD WORK

Auer rod-like inclusions in κ light chain myeloma
Jonathan Christopher Noujaim,Giovanni D’Angelo
View Articletitled, Auer rod-like inclusions in κ light chain myeloma
Favism in a 15-month-old baby
Muhajir Mohamed,Ingrid Els
View Articletitled, Favism in a 15-month-old baby

PLENARY PAPER

Identification of a cellular ligand for the natural cytotoxicity receptor NKp44
Florence Baychelier,Alexis Sennepin,Myriam Ermonval,Karim Dorgham,Patrice Debré,Vincent Vieillard
View Articletitled, Identification of a cellular ligand for the natural cytotoxicity receptor NKp44
Supplemental data

REVIEW ARTICLE

Diagnosis and treatment of primary myelodysplastic syndromes in adults: recommendations from the European LeukemiaNet
Luca Malcovati,Eva Hellström-Lindberg,David Bowen,Lionel Adès,Jaroslav Cermak,Consuelo del Cañizo,Matteo G. Della Porta,Pierre Fenaux,Norbert Gattermann,Ulrich Germing,Joop H. Jansen,Moshe Mittelman,Ghulam Mufti,Uwe Platzbecker,Guillermo F. Sanz,Dominik Selleslag,Mette Skov-Holm,Reinhard Stauder,Argiris Symeonidis,Arjan A. van de Loosdrecht,Theo de Witte,Mario Cazzola
View Articletitled, Diagnosis and treatment of primary myelodysplastic syndromes in adults: recommendations from the European LeukemiaNet
Supplemental data

CLINICAL TRIALS AND OBSERVATIONS

Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study
Clinical Trials & Observations
Conrad Russell Y. Cruz,Kenneth P. Micklethwaite,Barbara Savoldo,Carlos A. Ramos,Sharon Lam,Stephanie Ku,Oumar Diouf,Enli Liu,A. John Barrett,Sawa Ito,Elizabeth J. Shpall,Robert A. Krance,Rammurti T. Kamble,George Carrum,Chitra M. Hosing,Adrian P. Gee,Zhuyong Mei,Bambi J. Grilley,Helen E. Heslop,Cliona M. Rooney,Malcolm K. Brenner,Catherine M. Bollard,Gianpietro Dotti
View Articletitled, Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study
The impact of response on bone-directed therapy in patients with multiple myeloma
Clinical Trials & Observations Brief Report
Alessandra Larocca,J. Anthony Child,Gordon Cook,Graham H. Jackson,Nigel Russell,Alexander Szubert,Walter M. Gregory,Annamaria Brioli,Roger G. Owen,Mark T. Drayson,Ping Wu,Antonio Palumbo,Mario Boccadoro,Faith E. Davies,Gareth J. Morgan
View Articletitled, The impact of response on bone-directed therapy in patients with multiple myeloma

HEMATOPOIESIS AND STEM CELLS

DNA methylation of Runx1 regulatory regions correlates with transition from primitive to definitive hematopoietic potential in vitro and in vivo
Beau R. Webber,Michelina Iacovino,Si Ho Choi,Jakub Tolar,Michael Kyba,Bruce R. Blazar
View Articletitled, DNA methylation of <em>Runx1</em> regulatory regions correlates with transition from primitive to definitive hematopoietic potential in vitro and in vivo
Supplemental data
Nfix is a novel regulator of murine hematopoietic stem and progenitor cell survival
Per Holmfeldt,Jennifer Pardieck,Anjelica C. Saulsberry,Satish Kumar Nandakumar,David Finkelstein,John T. Gray,Derek A. Persons,Shannon McKinney-Freeman
View Articletitled, <em>Nfix</em> is a novel regulator of murine hematopoietic stem and progenitor cell survival
Supplemental data
Prostaglandin E2 enhances long-term repopulation but does not permanently alter inherent stem cell competitiveness
Brief Report
Jonathan Hoggatt,Khalid S. Mohammad,Pratibha Singh,Louis M. Pelus
View Articletitled, Prostaglandin E<sub>2</sub> enhances long-term repopulation but does not permanently alter inherent stem cell competitiveness

IMMUNOBIOLOGY

MicroRNA-146a regulates survival and maturation of human plasmacytoid dendritic cells
Julien J. Karrich,Loes C. M. Jachimowski,Marion Libouban,Anand Iyer,Kim Brandwijk,Esther W. Taanman-Kueter,Maho Nagasawa,Esther C. de Jong,Christel H. Uittenbogaart,Bianca Blom
View Articletitled, MicroRNA-146a regulates survival and maturation of human plasmacytoid dendritic cells
Supplemental data

LYMPHOID NEOPLASIA

IL-21 and CD40L signals from autologous T cells can induce antigen-independent proliferation of CLL cells
Maria Fernanda Pascutti,Margot Jak,Jacqueline M. Tromp,Ingrid A. M. Derks,Ester B. M. Remmerswaal,Rachel Thijssen,Martijn H. A. van Attekum,Gregor G. van Bochove,Dieuwertje M. Luijks,Steven T. Pals,René A. W. van Lier,Arnon P. Kater,Marinus H. J. van Oers,Eric Eldering
View Articletitled, IL-21 and CD40L signals from autologous T cells can induce antigen-independent proliferation of CLL cells
Supplemental data
Trogocytosis of multiple B-cell surface markers by CD22 targeting with epratuzumab
Edmund A. Rossi,David M. Goldenberg,Rosana Michel,Diane L. Rossi,Daniel J. Wallace,Chien-Hsing Chang
View Articletitled, Trogocytosis of multiple B-cell surface markers by CD22 targeting with epratuzumab
Supplemental data
Pivotal role of HIV and EBV replication in the long-term persistence of monoclonal gammopathy in patients on antiretroviral therapy
Brief Report
David Eric Ouedraogo,Alain Makinson,Jean-Pierre Vendrell,Marie-Laure Casanova,Nicolas Nagot,Renaud Cezar,Karine Bollore,Yassine Al Taaba,Vincent Foulongne,Stéphanie Badiou,Johannes Viljoen,Jacques Reynes,Philippe Van de Perre,Edouard Tuaillon
View Articletitled, Pivotal role of HIV and EBV replication in the long-term persistence of monoclonal gammopathy in patients on antiretroviral therapy
Supplemental data

MYELOID NEOPLASIA

Preclinical and clinical efficacy of XPO1/CRM1 inhibition by the karyopherin inhibitor KPT-330 in Ph+ leukemias
Christopher J. Walker,Joshua J. Oaks,Ramasamy Santhanam,Paolo Neviani,Jason G. Harb,Gregory Ferenchak,Justin J. Ellis,Yosef Landesman,Ann-Kathrin Eisfeld,Nash Y. Gabrail,Carrie L. Smith,Michael A. Caligiuri,Peter Hokland,Denis Claude Roy,Alistair Reid,Dragana Milojkovic,John M. Goldman,Jane Apperley,Ramiro Garzon,Guido Marcucci,Sharon Shacham,Michael G. Kauffman,Danilo Perrotti
View Articletitled, Preclinical and clinical efficacy of XPO1/CRM1 inhibition by the karyopherin inhibitor KPT-330 in Ph<sup>+</sup> leukemias
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

The common hereditary elliptocytosis-associated α-spectrin L260P mutation perturbs erythrocyte membranes by stabilizing spectrin in the closed dimer conformation
Sandra L. Harper,Sira Sriswasdi,Hsin-Yao Tang,Massimiliano Gaetani,Patrick G. Gallagher,David W. Speicher
View Articletitled, The common hereditary elliptocytosis-associated α-spectrin L260P mutation perturbs erythrocyte membranes by stabilizing spectrin in the closed dimer conformation
Supplemental data
A fully human anti-hepcidin antibody modulates iron metabolism in both mice and nonhuman primates
Keegan S. Cooke,Beth Hinkle,Hossein Salimi-Moosavi,Ian Foltz,Chadwick King,Palaniswami Rathanaswami,Aaron Winters,Shirley Steavenson,C. Glenn Begley,Graham Molineux,Barbra J. Sasu
View Articletitled, A fully human anti-hepcidin antibody modulates iron metabolism in both mice and nonhuman primates
Supplemental data

TRANSPLANTATION

Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality
Asim Saha,Kazutoshi Aoyama,Patricia A. Taylor,Brent H. Koehn,Rachelle G. Veenstra,Angela Panoskaltsis-Mortari,David H. Munn,William J. Murphy,Miyuki Azuma,Hideo Yagita,Brian T. Fife,Mohammed H. Sayegh,Nader Najafian,Gerard Socie,Rafi Ahmed,Gordon J. Freeman,Arlene H. Sharpe,Bruce R. Blazar
View Articletitled, Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality
Supplemental data
Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation
Clinical Trials & Observations
Corey Cutler,Pratik Multani,David Robbins,Haesook T. Kim,Thuy Le,Jonathan Hoggatt,Louis M. Pelus,Caroline Desponts,Yi-Bin Chen,Betsy Rezner,Philippe Armand,John Koreth,Brett Glotzbecker,Vincent T. Ho,Edwin Alyea,Marlisa Isom,Grace Kao,Myriam Armant,Leslie Silberstein,Peirong Hu,Robert J. Soiffer,David T. Scadden,Jerome Ritz,Wolfram Goessling,Trista E. North,John Mendlein,Karen Ballen,Leonard I. Zon,Joseph H. Antin,Daniel D. Shoemaker
View Articletitled, Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation
Supplemental data

CORRESPONDENCE

Reversible lymph node follicular hyperplasia associated with dasatinib treatment of chronic myeloid leukemia in chronic phase
Clinical Trials & Observations
Clémence Roux,Franck-Emmanuel Nicolini,Delphine Rea,Mathilde Niault,Luigina Mollica,Françoise Berger,Catherine Chassagne-Clément,Isabelle Tigaud,Michel Tulliez,Stéphane Giraudier,Ali Turhan,Philippe Rousselot,Laurence Legros
View Articletitled, Reversible lymph node follicular hyperplasia associated with dasatinib treatment of chronic myeloid leukemia in chronic phase
BRAF V600E is also seen in unclassifiable splenic B-cell lymphoma/leukemia, a potential mimic of hairy cell leukemia
Philipp W. Raess,David Mintzer,Michael Husson,Megan O. Nakashima,Jennifer J. D. Morrissette,Robert Daber,Adam Bagg
View Articletitled, <em>BRAF</em> V600E is also seen in unclassifiable splenic B-cell lymphoma/leukemia, a potential mimic of hairy cell leukemia
Activity of omacetaxine mepesuccinate against ponatinib-resistant BCR-ABL-positive cells
Seiichi Okabe,Tetsuzo Tauchi,Yuko Tanaka,Seiichiro Katagiri,Toshihiko Kitahara,Kazuma Ohyashiki
View Articletitled, Activity of omacetaxine mepesuccinate against ponatinib-resistant BCR-ABL-positive cells
Effect of congenital upregulation of hypoxia inducible factors on percentage of fetal hemoglobin in the blood
Juan Salomon-Andonie,Galina Miasnikova,Adelina Sergueeva,Lydia A. Polyakova,Xiaomei Niu,Sergei Nekhai,Victor R. Gordeuk
View Articletitled, Effect of congenital upregulation of hypoxia inducible factors on percentage of fetal hemoglobin in the blood

ERRATA

Balwani M, Desnick RJ. The porphyrias: advances in diagnosis and treatment. Blood. 2012;120(23):4496-4504.
View Articletitled, Balwani M, Desnick RJ. The porphyrias: advances in diagnosis and treatment. <em>Blood</em>. 2012;120(23):<span class="related-article">4496-4504</span>.
Wiestner A. Emerging role of kinase-targeted strategies in chronic lymphocytic leukemia. Blood. 2012;120(24):4684-4691.
View Articletitled, Wiestner A. Emerging role of kinase-targeted strategies in chronic lymphocytic leukemia. <em>Blood.</em> 2012;120(24):<span class="related-article">4684-4691</span>.
All Issues

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