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Limited effect of chemotherapy in cutaneous lymphoma
Dendritic cells and lymphoma cells: come together right now
Primary mediastinal B-cell lymphoma and mediastinal gray zone lymphoma: do they require a unique therapeutic approach?
GATA2 deficiency-associated bone marrow disorder differs from idiopathic aplastic anemia
Lack of durable disease control with chemotherapy for mycosis fungoides and Sézary syndrome: a comparative study of systemic therapy
Sequential intranodal immunotherapy induces antitumor immunity and correlated regression of disseminated follicular lymphoma
Issue Archive
January 1 2015
In this Issue
Table of Contents
EDITORIAL
INSIDE BLOOD COMMENTARIES
INSIDE BLOOD COMMENTARY
Limited effect of chemotherapy in cutaneous lymphoma
Clinical Trials & Observations
INSIDE BLOOD COMMENTARY
Dendritic cells and lymphoma cells: come together right now
Clinical Trials & Observations
PLENARY PAPER
PLENARY PAPER
The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia
Joni Van der Meulen,Viraj Sanghvi,Konstantinos Mavrakis,Kaat Durinck,Fang Fang,Filip Matthijssens,Pieter Rondou,Monica Rosen,Tim Pieters,Peter Vandenberghe,Eric Delabesse,Tim Lammens,Barbara De Moerloose,Björn Menten,Nadine Van Roy,Bruno Verhasselt,Bruce Poppe,Yves Benoit,Tom Taghon,Ari M. Melnick,Frank Speleman,Hans-Guido Wendel,Pieter Van Vlierberghe
REVIEW SERIES
REVIEW SERIES
Primary mediastinal B-cell lymphoma and mediastinal gray zone lymphoma: do they require a unique therapeutic approach?
Clinical Trials & Observations
REVIEW SERIES
REVIEW SERIES
CLINICAL TRIALS AND OBSERVATIONS
GATA2 deficiency-associated bone marrow disorder differs from idiopathic aplastic anemia
Clinical Trials & Observations
Karthik A. Ganapathi,Danielle M. Townsley,Amy P. Hsu,Diane C. Arthur,Christa S. Zerbe,Jennifer Cuellar-Rodriguez,Dennis D. Hickstein,Sergio D. Rosenzweig,Raul C. Braylan,Neal S. Young,Steven M. Holland,Katherine R. Calvo
Lack of durable disease control with chemotherapy for mycosis fungoides and Sézary syndrome: a comparative study of systemic therapy
Clinical Trials & Observations
Charlotte F. M. Hughes,Amit Khot,Christopher McCormack,Stephen Lade,David A. Westerman,Robert Twigger,Odette Buelens,Kate Newland,Constantine Tam,Michael Dickinson,Gail Ryan,David Ritchie,Colin Wood,H. Miles Prince
Sequential intranodal immunotherapy induces antitumor immunity and correlated regression of disseminated follicular lymphoma
Clinical Trials & Observations
Arne Kolstad,Shraddha Kumari,Mateusz Walczak,Ulf Madsbu,Trond Hagtvedt,Trond Velde Bogsrud,Gunnar Kvalheim,Harald Holte,Ellen Aurlien,Jan Delabie,Anne Tierens,Johanna Olweus
HEMATOPOIESIS AND STEM CELLS
CDK6 as a key regulator of hematopoietic and leukemic stem cell activation
Ruth Scheicher,Andrea Hoelbl-Kovacic,Florian Bellutti,Anca-Sarmiza Tigan,Michaela Prchal-Murphy,Gerwin Heller,Christine Schneckenleithner,María Salazar-Roa,Sabine Zöchbauer-Müller,Johannes Zuber,Marcos Malumbres,Karoline Kollmann,Veronika Sexl
IMMUNOBIOLOGY
Upregulation of FcγRIIb on monocytes is necessary to promote the superagonist activity of TGN1412
Khiyam Hussain,Chantal E. Hargreaves,Ali Roghanian,Robert J. Oldham,H. T. Claude Chan,C. Ian Mockridge,Ferdousi Chowdhury,Bjorn Frendéus,Kirsty S. Harper,Jonathan C. Strefford,Mark S. Cragg,Martin J. Glennie,Anthony P. Williams,Ruth R. French
LYMPHOID NEOPLASIA
Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia
Valentina Audrito,Sara Serra,Davide Brusa,Francesca Mazzola,Francesca Arruga,Tiziana Vaisitti,Marta Coscia,Rossana Maffei,Davide Rossi,Tao Wang,Giorgio Inghirami,Menico Rizzi,Gianluca Gaidano,Joe G. N. Garcia,Cynthia Wolberger,Nadia Raffaelli,Silvia Deaglio
Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma
Andre Weilemann,Michael Grau,Tabea Erdmann,Olaf Merkel,Ulduz Sobhiafshar,Ioannis Anagnostopoulos,Michael Hummel,Antje Siegert,Claudia Hayford,Hannelore Madle,Brigitte Wollert-Wulf,Iduna Fichtner,Bernd Dörken,Stephan Dirnhofer,Stephan Mathas,Martin Janz,N. C. Tolga Emre,Andreas Rosenwald,German Ott,Peter Lenz,Alexandar Tzankov,Georg Lenz
MYELOID NEOPLASIA
Mutational spectrum of myeloid malignancies with inv(3)/t(3;3) reveals a predominant involvement of RAS/RTK signaling pathways
Stefan Gröschel,Mathijs A. Sanders,Remco Hoogenboezem,Annelieke Zeilemaker,Marije Havermans,Claudia Erpelinck,Eric M. J. Bindels,H. Berna Beverloo,Hartmut Döhner,Bob Löwenberg,Konstanze Döhner,Ruud Delwel,Peter J. M. Valk
PLATELETS AND THROMBOPOIESIS
RED CELLS, IRON, AND ERYTHROPOIESIS
Mito-protective autophagy is impaired in erythroid cells of aged mtDNA-mutator mice
XiuJie Li-Harms,Sandra Milasta,John Lynch,Christopher Wright,Aashish Joshi,Rekha Iyengar,Geoffrey Neale,Xi Wang,Yong-Dong Wang,Tomas A. Prolla,James E. Thompson,Joseph T. Opferman,Douglas R. Green,John Schuetz,Mondira Kundu
THROMBOSIS AND HEMOSTASIS
SLAP/SLAP2 prevent excessive platelet (hem)ITAM signaling in thrombosis and ischemic stroke in mice
Deya Cherpokova,Markus Bender,Martina Morowski,Peter Kraft,Michael K. Schuhmann,Sarah M. Akbar,Cheryl S. Sultan,Craig E. Hughes,Christoph Kleinschnitz,Guido Stoll,Leonard L. Dragone,Steve P. Watson,Michael G. Tomlinson,Bernhard Nieswandt
TRANSPLANTATION
High day 28 ST2 levels predict for acute graft-versus-host disease and transplant-related mortality after cord blood transplantation
Doris M. Ponce,Patrick Hilden,Christen Mumaw,Sean M. Devlin,Marissa Lubin,Sergio Giralt,Jenna D. Goldberg,Alan Hanash,Katharine Hsu,Robert Jenq,Miguel-Angel Perales,Craig Sauter,Marcel R. M. van den Brink,James W. Young,Renier Brentjens,Nancy A. Kernan,Susan E. Prockop,Richard J. O’Reilly,Andromachi Scaradavou,Sophie Paczesny,Juliet N. Barker
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Cover Image
Cover Image
![issue cover]()
SLAP/SLAP2 deficiency in platelets results in a dramatic increase in infarct volume in a murine model of ischemic stroke. The image shows coronal brain sections 24 hours after focal cerebral ischemia induced in control mice (top; the red areas are vital tissue) or mice with Slap−/−/Slap2−/− platelets (bottom; the white areas are cerebral infarctions). See the article by Cherpokova et al on page 185.
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