Skip Nav Destination

Issue Archive

Select Decade

Select Year

Issue

Volume 102, Issue 5

September 1 2003

In this Issue

INSIDE BLOOD
BLOOD WORK
CHEMOKINES
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
PHAGOCYTES
RED CELLS
TRANSPLANTATION
CORRESPONDENCE

INSIDE BLOOD

Extending a welcome into the uterine bed...

B. Anne Croy

View Articletitled, Extending a welcome into the uterine bed...

Don't GO to VOD

Scott I. Bearman

View Articletitled, Don't GO to VOD

Sirolimus and tacrolimus binding proteins: double-edged swords for GVHD prophylaxis

Hans-Peter Kiem,Claudio Anasetti

View Articletitled, Sirolimus and tacrolimus binding proteins: double-edged swords for GVHD prophylaxis

A (DNA) stitch in time saves nine

Gary Van Zant

View Articletitled, A (DNA) stitch in time saves nine

Hypoxia-inducible factors and marrow stromal function

Peter T. Curtin

View Articletitled, Hypoxia-inducible factors and marrow stromal function

Use of CD28 agonists to refill the T-cell tank?

Carl H. June

View Articletitled, Use of CD28 agonists to refill the T-cell tank?

Aberrant somatic hypermutation and lymphomagenesis

Nicholas Chiorazzi

View Articletitled, Aberrant somatic hypermutation and lymphomagenesis

Ara-G Fas L–itates T-cell death

B. Douglas Smith,Judith E. Karp

View Articletitled, Ara-G Fas L–itates T-cell death

AML: clustering genes to predict outcome

Scott A. Ness

View Articletitled, AML: clustering genes to predict outcome

More is not always better

Dong-Er Zhang

View Articletitled, More is not always better

The iron gatekeeper: keys to the front and back doors

Robert E. Fleming,William S. Sly

View Articletitled, The iron gatekeeper: keys to the front and back doors

BLOOD WORK

Peripheral smear from a patient with β thalassemia–HbE disease

View Articletitled, Peripheral smear from a patient with β thalassemia–HbE disease

CHEMOKINES

CXCL12 expression by invasive trophoblasts induces the specific migration of CD16^– human natural killer cells

Jacob Hanna,Ori Wald,Debra Goldman-Wohl,Diana Prus,Gal Markel,Roi Gazit,Gil Katz,Ronit Haimov-Kochman,Nobutaka Fujii,Simcha Yagel,Amnon Peled,Ofer Mandelboim

View Articletitled, CXCL12 expression by invasive trophoblasts induces the specific migration of CD16– human natural killer cells

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Prior gemtuzumab ozogamicin exposure significantly increases the risk of veno-occlusive disease in patients who undergo myeloablative allogeneic stem cell transplantation
Clinical Trials & Observations

Martha Wadleigh,Paul G. Richardson,David Zahrieh,Stephanie J. Lee,Corey Cutler,Vincent Ho,Edwin P. Alyea,Joseph H. Antin,Richard M. Stone,Robert J. Soiffer,Daniel J. DeAngelo

View Articletitled, Prior gemtuzumab ozogamicin exposure significantly increases the risk of veno-occlusive disease in patients who undergo myeloablative allogeneic stem cell transplantation

Safety and effectiveness of long-term therapy with the oral iron chelator deferiprone
Clinical Trials & Observations

Alan R. Cohen,Renzo Galanello,Antonio Piga,Vincenzo De Sanctis,Fernando Tricta

View Articletitled, Safety and effectiveness of long-term therapy with the oral iron chelator deferiprone

Cyclin D1 overexpression is a favorable prognostic variable for newly diagnosed multiple myeloma patients treated with high-dose chemotherapy and single or double autologous transplantation
Clinical Trials & Observations

Simona Soverini,Michele Cavo,Claudia Cellini,Carolina Terragna,Elena Zamagni,Deborah Ruggeri,Nicoletta Testoni,Patrizia Tosi,Antonio de Vivo,Marilina Amabile,Tiziana Grafone,Emanuela Ottaviani,Barbara Giannini,Delia Cangini,Francesca Bonifazi,Antonino Neri,Sonia Fabris,Sante Tura,Michele Baccarani,Giovanni Martinelli

View Articletitled, Cyclin D1 overexpression is a favorable prognostic variable for newly diagnosed multiple myeloma patients treated with high-dose chemotherapy and single or double autologous transplantation

Autologous transplantation of granulocyte colony-stimulating factor–primed bone marrow is effective in supporting myeloablative chemotherapy in patients with hematologic malignancies and poor peripheral blood stem cell mobilization
Clinical Trials & Observations

Roberto M. Lemoli,Antonio de Vivo,Daniela Damiani,Alessandro Isidori,Monica Tani,Alessandro Bonini,Claudia Cellini,Antonio Curti,Luigi Gugliotta,Giuseppe Visani,Renato Fanin,Michele Baccarani

View Articletitled, Autologous transplantation of granulocyte colony-stimulating factor–primed bone marrow is effective in supporting myeloablative chemotherapy in patients with hematologic malignancies and poor peripheral blood stem cell mobilization

Sirolimus, tacrolimus, and low-dose methotrexate for graft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation
Clinical Trials & Observations

Joseph H. Antin,Haesook T. Kim,Corey Cutler,Vincent T. Ho,Stephanie J. Lee,David B. Miklos,Ephraim P. Hochberg,Catherine J. Wu,Edwin P. Alyea,Robert J. Soiffer

View Articletitled, Sirolimus, tacrolimus, and low-dose methotrexate for graft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation

A phase 2 trial of CHOP chemotherapy followed by tositumomab/iodine I 131 tositumomab for previously untreated follicular non-Hodgkin lymphoma: Southwest Oncology Group Protocol S9911
Clinical Trials & Observations

Oliver W. Press,Joseph M. Unger,Rita M. Braziel,David G. Maloney,Thomas P. Miller,Michael LeBlanc,Ellen R. Gaynor,Saul E. Rivkin,Richard I. Fisher

View Articletitled, A phase 2 trial of CHOP chemotherapy followed by tositumomab/iodine I 131 tositumomab for previously untreated follicular non-Hodgkin lymphoma: Southwest Oncology Group Protocol S9911

BAALC expression predicts clinical outcome of de novo acute myeloid leukemia patients with normal cytogenetics: a Cancer and Leukemia Group B Study
Clinical Trials & Observations

Claudia D. Baldus,Stephan M. Tanner,Amy S. Ruppert,Susan P. Whitman,Kellie J. Archer,Guido Marcucci,Michael A. Caligiuri,Andrew J. Carroll,James W. Vardiman,Bayard L. Powell,Steven L. Allen,Joseph O. Moore,Richard A. Larson,Jonathan E. Kolitz,Albert de la Chapelle,Clara D. Bloomfield

View Articletitled, BAALC expression predicts clinical outcome of de novo acute myeloid leukemia patients with normal cytogenetics: a Cancer and Leukemia Group B Study

Microsatellite polymorphism in heme oxygenase-1 gene promoter is associated with susceptibility to oxidant-induced apoptosis in lymphoblastoid cell lines
Clinical Trials & Observations Brief Report

Hisao Hirai,Hiroshi Kubo,Mutsuo Yamaya,Katsutoshi Nakayama,Muneo Numasaki,Seiichi Kobayashi,Satoshi Suzuki,Shigeki Shibahara,Hidetada Sasaki

View Articletitled, Microsatellite polymorphism in heme oxygenase-1 gene promoter is associated with susceptibility to oxidant-induced apoptosis in lymphoblastoid cell lines

Contribution of β-2 microglobulin levels to the prognostic stratification of survival in patients with myelodysplastic syndrome (MDS)
Clinical Trials & Observations Brief Report

Simona Gatto,Greg Ball,Francesco Onida,Hagop M. Kantarjian,Elihu H. Estey,Miloslav Beran

View Articletitled, Contribution of β-2 microglobulin levels to the prognostic stratification of survival in patients with myelodysplastic syndrome (MDS)

HEMATOPOIESIS

Repopulating defect of mismatch repair–deficient hematopoietic stem cells

Jane S. Reese,Lili Liu,Stanton L. Gerson

View Articletitled, Repopulating defect of mismatch repair–deficient hematopoietic stem cells

The HIF family member EPAS1/HIF-2α is required for normal hematopoiesis in mice

Marzia Scortegagna,Margaret A. Morris,Yavuz Oktay,Michael Bennett,Joseph A. Garcia

View Articletitled, The HIF family member EPAS1/HIF-2α is required for normal hematopoiesis in mice

Hematopoietic stimulation by a dipeptidyl peptidase inhibitor reveals a novel regulatory mechanism and therapeutic treatment for blood cell deficiencies

Barry Jones,Sharlene Adams,Glenn T. Miller,Michael I. Jesson,Takeshi Watanabe,Barbara P. Wallner

View Articletitled, Hematopoietic stimulation by a dipeptidyl peptidase inhibitor reveals a novel regulatory mechanism and therapeutic treatment for blood cell deficiencies

In vitro generation of T lymphocytes from embryonic stem cell–derived prehematopoietic progenitors

Renée F. de Pooter,Sarah K. Cho,James R. Carlyle,Juan Carlos Zúñiga-Pflücker

View Articletitled, In vitro generation of T lymphocytes from embryonic stem cell–derived prehematopoietic progenitors

Hair follicles serve as local reservoirs of skin mast cell precursors

Tadashi Kumamoto,David Shalhevet,Hiroyuki Matsue,Mark E. Mummert,Brant R. Ward,James V. Jester,Akira Takashima

View Articletitled, Hair follicles serve as local reservoirs of skin mast cell precursors

Identification of differentially expressed genes representing dendritic cell precursors and their progeny

Heather L. Wilson,Helen C. O'Neill

View Articletitled, Identification of differentially expressed genes representing dendritic cell precursors and their progeny

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Drug-induced thrombocytopenia: localization of the binding site of GPIX-specific quinine-dependent antibodies

Parisa Asvadi,Zohra Ahmadi,Beng H. Chong

View Articletitled, Drug-induced thrombocytopenia: localization of the binding site of GPIX-specific quinine-dependent antibodies

Impaired selectin-ligand biosynthesis and reduced inflammatory responses in β-1,4-galactosyltransferase-I–deficient mice

Masahide Asano,Susumu Nakae,Norihiro Kotani,Naoki Shirafuji,Aya Nambu,Noriyoshi Hashimoto,Hiroto Kawashima,Mayumi Hirose,Masayuki Miyasaka,Seiichi Takasaki,Yoichiro Iwakura

View Articletitled, Impaired selectin-ligand biosynthesis and reduced inflammatory responses in β-1,4-galactosyltransferase-I–deficient mice

The APC-independent anticoagulant activity of protein S in plasma is decreased by elevated prothrombin levels due to the prothrombin G20210A mutation
Clinical Trials & Observations

Rory R. Koenen,Guido Tans,René van Oerle,Karly Hamulyák,Jan Rosing,Tilman M. Hackeng

View Articletitled, The APC-independent anticoagulant activity of protein S in plasma is decreased by elevated prothrombin levels due to the prothrombin G20210A mutation

Synergistic effect of sphingosine 1-phosphate on thrombin-induced tissue factor expression in endothelial cells

Hiroyuki Takeya,Esteban C. Gabazza,Shinya Aoki,Hikaru Ueno,Koji Suzuki

View Articletitled, Synergistic effect of sphingosine 1-phosphate on thrombin-induced tissue factor expression in endothelial cells

The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletion

Kazunobu Kato,Taisuke Kanaji,Susan Russell,Thomas J. Kunicki,Kenichi Furihata,Sachiko Kanaji,Patrizia Marchese,Armin Reininger,Zaverio M. Ruggeri,Jerry Ware

View Articletitled, The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletion

Supplemental data

Antiapoptotic effect of coagulation factor VIIa

Brit B. Sorensen,L. Vijaya Mohan Rao,Ditte Tornehave,Steen Gammeltoft,Lars C. Petersen

View Articletitled, Antiapoptotic effect of coagulation factor VIIa

Granule stores from cellubrevin/VAMP-3 null mouse platelets exhibit normal stimulus-induced release

Todd D. Schraw,Tara W. Rutledge,Garland L. Crawford,Audrey M. Bernstein,Amanda L. Kalen,Jeffery E. Pessin,Sidney W. Whiteheart

View Articletitled, Granule stores from cellubrevin/VAMP-3 null mouse platelets exhibit normal stimulus-induced release

Regulation of plasminogen activation: a role for melanotransferrin (p97) in cell migration

Michel Demeule,Yanick Bertrand,Jonathan Michaud-Levesque,Julie Jodoin,Yannève Rolland,Reinhard Gabathuler,Richard Béliveau

View Articletitled, Regulation of plasminogen activation: a role for melanotransferrin (p97) in cell migration

Heme and lipid peroxides in hemoglobin-modified low-density lipoprotein mediate cell survival and adaptation to oxidative stress

Liana Asatryan,Ouliana Ziouzenkova,Roger Duncan,Alex Sevanian

View Articletitled, Heme and lipid peroxides in hemoglobin-modified low-density lipoprotein mediate cell survival and adaptation to oxidative stress

Bacterial lipopolysaccharide directly induces angiogenesis through TRAF6-mediated activation of NF-κB and c-Jun N-terminal kinase
Brief Report

Ingrid Pollet,Christy J. Opina,Carla Zimmerman,Kevin G. Leong,Fred Wong,Aly Karsan

View Articletitled, Bacterial lipopolysaccharide directly induces angiogenesis through TRAF6-mediated activation of NF-κB and c-Jun N-terminal kinase

Decreased factor VIII levels during acetaminophen-induced murine fulminant hepatic failure
Brief Report

Christopher B. Doering,Ernest T. Parker,Christopher E. Nichols,Pete Lollar

View Articletitled, Decreased factor VIII levels during acetaminophen-induced murine fulminant hepatic failure

IMMUNOBIOLOGY

CD2 engagement induces dendritic cell activation: implications for immune surveillance and T-cell activation

Keith Crawford,Aleksandra Stark,Betsy Kitchens,Kerry Sternheim,Vassilios Pantazopoulos,Ellen Triantafellow,Zhigang Wang,Baldev Vasir,Charles E. Larsen,Dana Gabuzda,Ellis Reinherz,Chester A. Alper

View Articletitled, CD2 engagement induces dendritic cell activation: implications for immune surveillance and T-cell activation

Functional comparison of DCs generated in vivo with Flt3 ligand or in vitro from blood monocytes: differential regulation of function by specific classes of physiologic stimuli

Michael Jefford,Max Schnurr,Tracey Toy,Kelly-Anne Masterman,Amanda Shin,Tina Beecroft,Tsin Yee Tai,Ken Shortman,Mark Shackleton,Ian D. Davis,Phil Parente,Thomas Luft,Weisan Chen,Jonathan Cebon,Eugene Maraskovsky

View Articletitled, Functional comparison of DCs generated in vivo with Flt3 ligand or in vitro from blood monocytes: differential regulation of function by specific classes of physiologic stimuli

Rapid recovery from T lymphopenia by CD28 superagonist therapy

Karin Elflein,Marta Rodriguez-Palmero,Thomas Kerkau,Thomas Hünig

View Articletitled, Rapid recovery from T lymphopenia by CD28 superagonist therapy

Induction of FucT-VII by the Ras/MAP kinase cascade in Jurkat T cells

Sheila M. Barry,Dimitrios G. Zisoulis,Joel W. Neal,Neil A. Clipstone,Geoffrey S. Kansas

View Articletitled, Induction of FucT-VII by the Ras/MAP kinase cascade in Jurkat T cells

Ex vivo characterization of human CD8⁺ T subsets with distinct replicative history and partial effector functions

Nathalie Rufer,Alfred Zippelius,Pascal Batard,Mikaël J. Pittet,Isabel Kurth,Patricia Corthesy,Jean-Charles Cerottini,Serge Leyvraz,Eddy Roosnek,Markus Nabholz,Pedro Romero

View Articletitled, Ex vivo characterization of human CD8+ T subsets with distinct replicative history and partial effector functions

Heat shock protein 70 binds caspase-activated DNase and enhances its activity in TCR-stimulated T cells

Qing-Li Liu,Hiroyuki Kishi,Kenzo Ohtsuka,Atsushi Muraguchi

View Articletitled, Heat shock protein 70 binds caspase-activated DNase and enhances its activity in TCR-stimulated T cells

Expression and function of KIR and natural cytotoxicity receptors in NK-type lymphoproliferative diseases of granular lymphocytes

Renato Zambello,Michela Falco,Mariella Della Chiesa,Livio Trentin,Davide Carollo,Roberta Castriconi,Giovanna Cannas,Simona Carlomagno,Anna Cabrelle,Thierry Lamy,Carlo Agostini,Alessandro Moretta,Gianpietro Semenzato,Massimo Vitale

View Articletitled, Expression and function of KIR and natural cytotoxicity receptors in NK-type lymphoproliferative diseases of granular lymphocytes

Disease-associated dendritic cells respond to disease-specific antigens through the common heat shock protein receptor

Justin Stebbing,Brian Gazzard,Simon Portsmouth,Frances Gotch,Louise Kim,Mark Bower,Sundhiya Mandalia,Robert Binder,Pramod Srivastava,Steve Patterson

View Articletitled, Disease-associated dendritic cells respond to disease-specific antigens through the common heat shock protein receptor

Immunotherapy of tumors with vaccine based on quail homologous vascular endothelial growth factor receptor-2

Ji-yan Liu,Yu-quan Wei,Li Yang,Xia Zhao,Ling Tian,Jian-mei Hou,Ting Niu,Fen Liu,Yu Jiang,Bing Hu,Yang Wu,Jing-mei Su,Yan-yan Lou,Qiu-ming He,Yan-jun Wen,Jin-liang Yang,Bing Kan,Yong-qiu Mao,Feng Luo,Feng Peng

View Articletitled, Immunotherapy of tumors with vaccine based on quail homologous vascular endothelial growth factor receptor-2

NEOPLASIA

Synergistic antileukemic interactions between 17-AAG and UCN-01 involve interruption of RAF/MEK- and AKT-related pathways

Wentao Jia,Chunrong Yu,Mohamed Rahmani,Geoffrey Krystal,Edward A. Sausville,Paul Dent,Steven Grant

View Articletitled, Synergistic antileukemic interactions between 17-AAG and UCN-01 involve interruption of RAF/MEK- and AKT-related pathways

Aberrant somatic hypermutation in multiple subtypes of AIDS-associated non-Hodgkin lymphoma

Gianluca Gaidano,Laura Pasqualucci,Daniela Capello,Eva Berra,Clara Deambrogi,Davide Rossi,Luigi Maria Larocca,Annunziata Gloghini,Antonino Carbone,Riccardo Dalla-Favera

View Articletitled, Aberrant somatic hypermutation in multiple subtypes of AIDS-associated non-Hodgkin lymphoma

Mechanisms for T-cell selective cytotoxicity of arabinosylguanine

Carlos O. Rodriguez, Jr,Christine M. Stellrecht,Varsha Gandhi

View Articletitled, Mechanisms for T-cell selective cytotoxicity of arabinosylguanine

Identification of a gene expression signature associated with pediatric AML prognosis

Tomohito Yagi,Akira Morimoto,Mariko Eguchi,Shigeyoshi Hibi,Masahiro Sako,Eiichi Ishii,Shuki Mizutani,Shinsaku Imashuku,Misao Ohki,Hitoshi Ichikawa

View Articletitled, Identification of a gene expression signature associated with pediatric AML prognosis

Supplemental data

High-penetrance mouse model of acute promyelocytic leukemia with very low levels of PML-RARα expression

Peter Westervelt,Andrew A. Lane,Jessica L. Pollock,Kristie Oldfather,Matthew S. Holt,Drazen B. Zimonjic,Nicholas C. Popescu,John F. DiPersio,Timothy J. Ley

View Articletitled, High-penetrance mouse model of acute promyelocytic leukemia with very low levels of PML-RARα expression

Increased apoptosis in bone marrow B lymphocytes but not T lymphocytes in myelodysplastic syndrome
Brief Report

Hesham M. Amin,Iman Jilani,Elihu H. Estey,Michael J. Keating,Amanda L. Dey,Taghi Manshouri,Hagop M. Kantarjian,Zeev Estrov,Jorge E. Cortes,Deborah A. Thomas,Francis J. Giles,Maher Albitar

View Articletitled, Increased apoptosis in bone marrow B lymphocytes but not T lymphocytes in myelodysplastic syndrome

Comparison of molecular markers in a cohort of patients with chronic myeloproliferative disorders
Brief Report

Robert Kralovics,Andreas S. Buser,Soon-Siong Teo,Jörn Coers,Andre Tichelli,Anthonie P. C. van der Maas,Radek C. Skoda

View Articletitled, Comparison of molecular markers in a cohort of patients with chronic myeloproliferative disorders

Intronic BCL-6 mutations are preferentially targeted to the translocated allele in t(3;14)(q27;q32) non-Hodgkin B-cell lymphoma
Brief Report

Fabrice Jardin,Christian Bastard,Nathalie Contentin,Françoise Parmentier,Jean-Michel Picquenot,Hervé Tilly,Freda K. Stevenson,Surinder S. Sahota

View Articletitled, Intronic BCL-6 mutations are preferentially targeted to the translocated allele in t(3;14)(q27;q32) non-Hodgkin B-cell lymphoma

PHAGOCYTES

Syk activation is a leukotriene B₄–regulated event involved in macrophage phagocytosis of IgG-coated targets but not apoptotic cells

Claudio Canetti,Bin Hu,Jeffrey L. Curtis,Marc Peters-Golden

View Articletitled, Syk activation is a leukotriene B4–regulated event involved in macrophage phagocytosis of IgG-coated targets but not apoptotic cells

Iron, manganese, and cobalt transport by Nramp1 (Slc11a1) and Nramp2 (Slc11a2) expressed at the plasma membrane

John R. Forbes,Philippe Gros

View Articletitled, Iron, manganese, and cobalt transport by Nramp1 (Slc11a1) and Nramp2 (Slc11a2) expressed at the plasma membrane

RED CELLS

Systemic regulation of Hephaestin and Ireg1 revealed in studies of genetic and nutritional iron deficiency

Huijun Chen,Trent Su,Zouhair K. Attieh,Tama C. Fox,Andrew T. McKie,Gregory J. Anderson,Chris D. Vulpe

View Articletitled, Systemic regulation of Hephaestin and Ireg1 revealed in studies of genetic and nutritional iron deficiency

Molecular characterization of Turkish patients with pyrimidine 5′ nucleotidase-I deficiency

Gunay Balta,Fatma Gumruk,Nurten Akarsu,Aytemiz Gurgey,Cigdem Altay

View Articletitled, Molecular characterization of Turkish patients with pyrimidine 5′ nucleotidase-I deficiency

Molecular analyses of patients with hyperferritinemia and normal serum iron values reveal both L ferritin IRE and 3 new ferroportin (slc11A3) mutations
Clinical Trials & Observations

Gilles Hetet,Isabelle Devaux,Nadem Soufir,Bernard Grandchamp,Carole Beaumont

View Articletitled, Molecular analyses of patients with hyperferritinemia and normal serum iron values reveal both L ferritin IRE and 3 new ferroportin (slc11A3) mutations

Supplemental data

Mature parasite-infected erythrocyte surface antigen (MESA) of Plasmodium falciparum binds to the 30-kDa domain of protein 4.1 in malaria-infected red blood cells
Brief Report

Karena L. Waller,Wataru Nunomura,Xiuli An,Brian M. Cooke,Narla Mohandas,Ross L. Coppel

View Articletitled, Mature parasite-infected erythrocyte surface antigen (MESA) of Plasmodium falciparum binds to the 30-kDa domain of protein 4.1 in malaria-infected red blood cells

TRANSPLANTATION

Rapid and complete donor chimerism in adult recipients of unrelated donor umbilical cord blood transplantation after reduced-intensity conditioning
Clinical Trials & Observations

Juliet N. Barker,Daniel J. Weisdorf,Todd E. DeFor,Bruce R. Blazar,Jeffrey S. Miller,John E. Wagner

View Articletitled, Rapid and complete donor chimerism in adult recipients of unrelated donor umbilical cord blood transplantation after reduced-intensity conditioning

Mechanisms of donor-specific transfusion tolerance: preemptive induction of clonal T-cell exhaustion via indirect presentation

Sergio A. Quezada,Bruce Fuller,Lamis Z. Jarvinen,Mercedes Gonzalez,Bruce R. Blazar,Alexander Y. Rudensky,Terry B. Strom,Randolph J. Noelle

View Articletitled, Mechanisms of donor-specific transfusion tolerance: preemptive induction of clonal T-cell exhaustion via indirect presentation

Molecular remission after myeloablative allogeneic stem cell transplantation predicts a better relapse-free survival in patients with multiple myeloma
Brief Report

Paolo Corradini,Michele Cavo,Henk Lokhorst,Giovanni Martinelli,Carolina Terragna,Ignazio Majolino,Pinuccia Valagussa,Mario Boccadoro,Diana Samson,Andrea Bacigalupo,Nigel Russell,Vittorio Montefusco,Claudia Voena,Gosta Gahrton,the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation (EBMT)

View Articletitled, Molecular remission after myeloablative allogeneic stem cell transplantation predicts a better relapse-free survival in patients with multiple myeloma

CORRESPONDENCE

Fatal hepatitis B virus reactivation by an escape mutant following rituximab therapy

Timm H. Westhoff,Friederike Jochimsen,Alexander Schmittel,Marina Stöffler-Meilicke,Jürgen H. Schäfer,Walter Zidek,Wolfram H. Gerlich,Eckhard Thiel

View Articletitled, Fatal hepatitis B virus reactivation by an escape mutant following rituximab therapy

Cover Image

Cover Image

All Issues

Advertisement intended for health care professionals

Email alerts

First Edition Alert

Latest Issue Alert

Latest
Most Read
Most Cited

Mosunetuzumab next up to bat … is it a home run?

Novel CAR T cells to combat antigen escape in AML

Heme fuels venetoclax resistance in multiple myeloma

Introduction to a review series on mantle cell lymphoma: sands shifting in the darkness

Sequential epigenetic therapy in AML

Advertisement intended for health care professionals

Issue Archive

Table of Contents

INSIDE BLOOD

BLOOD WORK

CHEMOKINES

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Prior gemtuzumab ozogamicin exposure significantly increases the risk of veno-occlusive disease in patients who undergo myeloablative allogeneic stem cell transplantation Clinical Trials & Observations

Safety and effectiveness of long-term therapy with the oral iron chelator deferiprone Clinical Trials & Observations

Cyclin D1 overexpression is a favorable prognostic variable for newly diagnosed multiple myeloma patients treated with high-dose chemotherapy and single or double autologous transplantation Clinical Trials & Observations

Autologous transplantation of granulocyte colony-stimulating factor–primed bone marrow is effective in supporting myeloablative chemotherapy in patients with hematologic malignancies and poor peripheral blood stem cell mobilization Clinical Trials & Observations

Sirolimus, tacrolimus, and low-dose methotrexate for graft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation Clinical Trials & Observations

A phase 2 trial of CHOP chemotherapy followed by tositumomab/iodine I 131 tositumomab for previously untreated follicular non-Hodgkin lymphoma: Southwest Oncology Group Protocol S9911 Clinical Trials & Observations

BAALC expression predicts clinical outcome of de novo acute myeloid leukemia patients with normal cytogenetics: a Cancer and Leukemia Group B Study Clinical Trials & Observations

Microsatellite polymorphism in heme oxygenase-1 gene promoter is associated with susceptibility to oxidant-induced apoptosis in lymphoblastoid cell lines Clinical Trials & Observations Brief Report

Contribution of β-2 microglobulin levels to the prognostic stratification of survival in patients with myelodysplastic syndrome (MDS) Clinical Trials & Observations Brief Report

HEMATOPOIESIS

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

The APC-independent anticoagulant activity of protein S in plasma is decreased by elevated prothrombin levels due to the prothrombin G20210A mutation Clinical Trials & Observations

Bacterial lipopolysaccharide directly induces angiogenesis through TRAF6-mediated activation of NF-κB and c-Jun N-terminal kinase Brief Report

Decreased factor VIII levels during acetaminophen-induced murine fulminant hepatic failure Brief Report

IMMUNOBIOLOGY

NEOPLASIA

Increased apoptosis in bone marrow B lymphocytes but not T lymphocytes in myelodysplastic syndrome Brief Report

Comparison of molecular markers in a cohort of patients with chronic myeloproliferative disorders Brief Report

Intronic BCL-6 mutations are preferentially targeted to the translocated allele in t(3;14)(q27;q32) non-Hodgkin B-cell lymphoma Brief Report

PHAGOCYTES

RED CELLS

Molecular analyses of patients with hyperferritinemia and normal serum iron values reveal both L ferritin IRE and 3 new ferroportin (slc11A3) mutations Clinical Trials & Observations

Mature parasite-infected erythrocyte surface antigen (MESA) of Plasmodium falciparum binds to the 30-kDa domain of protein 4.1 in malaria-infected red blood cells Brief Report

TRANSPLANTATION

Rapid and complete donor chimerism in adult recipients of unrelated donor umbilical cord blood transplantation after reduced-intensity conditioning Clinical Trials & Observations

Molecular remission after myeloablative allogeneic stem cell transplantation predicts a better relapse-free survival in patients with multiple myeloma Brief Report

CORRESPONDENCE

Cover Image

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only

Prior gemtuzumab ozogamicin exposure significantly increases the risk of veno-occlusive disease in patients who undergo myeloablative allogeneic stem cell transplantation
Clinical Trials & Observations

Safety and effectiveness of long-term therapy with the oral iron chelator deferiprone
Clinical Trials & Observations

Cyclin D1 overexpression is a favorable prognostic variable for newly diagnosed multiple myeloma patients treated with high-dose chemotherapy and single or double autologous transplantation
Clinical Trials & Observations

Autologous transplantation of granulocyte colony-stimulating factor–primed bone marrow is effective in supporting myeloablative chemotherapy in patients with hematologic malignancies and poor peripheral blood stem cell mobilization
Clinical Trials & Observations

Sirolimus, tacrolimus, and low-dose methotrexate for graft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation
Clinical Trials & Observations

A phase 2 trial of CHOP chemotherapy followed by tositumomab/iodine I 131 tositumomab for previously untreated follicular non-Hodgkin lymphoma: Southwest Oncology Group Protocol S9911
Clinical Trials & Observations

BAALC expression predicts clinical outcome of de novo acute myeloid leukemia patients with normal cytogenetics: a Cancer and Leukemia Group B Study
Clinical Trials & Observations

Microsatellite polymorphism in heme oxygenase-1 gene promoter is associated with susceptibility to oxidant-induced apoptosis in lymphoblastoid cell lines
Clinical Trials & Observations Brief Report

Contribution of β-2 microglobulin levels to the prognostic stratification of survival in patients with myelodysplastic syndrome (MDS)
Clinical Trials & Observations Brief Report

The APC-independent anticoagulant activity of protein S in plasma is decreased by elevated prothrombin levels due to the prothrombin G20210A mutation
Clinical Trials & Observations

Bacterial lipopolysaccharide directly induces angiogenesis through TRAF6-mediated activation of NF-κB and c-Jun N-terminal kinase
Brief Report

Decreased factor VIII levels during acetaminophen-induced murine fulminant hepatic failure
Brief Report

Increased apoptosis in bone marrow B lymphocytes but not T lymphocytes in myelodysplastic syndrome
Brief Report

Comparison of molecular markers in a cohort of patients with chronic myeloproliferative disorders
Brief Report

Intronic BCL-6 mutations are preferentially targeted to the translocated allele in t(3;14)(q27;q32) non-Hodgkin B-cell lymphoma
Brief Report

Molecular analyses of patients with hyperferritinemia and normal serum iron values reveal both L ferritin IRE and 3 new ferroportin (slc11A3) mutations
Clinical Trials & Observations

Mature parasite-infected erythrocyte surface antigen (MESA) of Plasmodium falciparum binds to the 30-kDa domain of protein 4.1 in malaria-infected red blood cells
Brief Report

Rapid and complete donor chimerism in adult recipients of unrelated donor umbilical cord blood transplantation after reduced-intensity conditioning
Clinical Trials & Observations

Molecular remission after myeloablative allogeneic stem cell transplantation predicts a better relapse-free survival in patients with multiple myeloma
Brief Report