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Journal Articles

CXCL9 as a novel prognostic marker to identify high-risk adults with hemophagocytic lymphohistiocytosis

Joseph M. Rocco, Joseph H. Oved, Rikita J Patel, A Zara Herskovits, Namitha Nair, Bita Shakoory, Thomas Robertson, Rachel Dileo, Max W Jacobs, Christa Zerbe, Rachael Gordon, Michael Joseph Ombrello, Amanda K Ombrello, Nirali N Shah, Dimana Dimitrova, Jennifer A Kanakry, Andrew D. Zelenetz, Alison J Moskowitz, Robert N Stuver, Zachary D Epstein-Peterson, Paola Ghione, Elena Mead, Zainab Shahid, Sergio A. Giralt, Sandeep S Raj, Jae H Park, Ivan Maillard, Mark B. Geyer, Wenbin Xiao, Ahmet Dogan, Megan S Lim, Jeffrey I. Zwicker, Jodi V. Mones, Rehka Parameswaran, Lauren G Banaszak, Shamir Geller, Bianca D. Santomasso, Roni Shouval, Kevin J. Curran, Ottavia M Delmonte, Luigi D Notarangelo, Jeffrey I Cohen, Steven M. Holland, Gilles A. Salles, Steven M Horwitz, Santosha A Vardhana, Miguel-Angel Perales, Daniella Schwartz, Irini Sereti, William T. Johnson

Blood blood.2025030976.

https://doi.org/10.1182/blood.2025030976

Published: 2025

Includes: Supplemental data

Journal Articles

Increased Prevalence of Clonal Hematopoiesis in Children with Sickle Cell Disease

Jessica Ulloa, Kristin Wuichet, Sara R Rashkin, Yash Pershad, Connor Shore, Caitlyn Vlasschaert, Mark J. Rodeghier, Yu Yao, Victor R Gordeuk, Binal N Shah, Clifford M. Takemoto, Santosh L Saraf, Michael R DeBaun, Mitchell J. Weiss, Alexander G. Bick

Blood blood.2025030898.

https://doi.org/10.1182/blood.2025030898

Published: 2025

Includes: Supplemental data

Journal Articles

Genomic Determinants of Response and Resistance to Pirtobrutinib in Relapsed/Refractory Chronic Lymphocytic Leukemia

Blood blood.2024027009.

https://doi.org/10.1182/blood.2024027009

Published: 2025

Includes: Supplemental data

Journal Articles

Driving CAR-Ts SafeSLE

Challice L. Bonifant, Nirali N. Shah

Blood (2025) 146 (9): 1034–1035.

https://doi.org/10.1182/blood.2025030096

Published: 2025

Journal Articles

T-ICAHT: grading and prognostic impact of thrombocytopenia after CAR T-cell therapy

Blood (2025) 146 (7): 834–846.

https://doi.org/10.1182/blood.2025028833

Published: 2025

Includes: Supplemental data

Journal Articles

Project EVOLVE: an international analysis of postimmunotherapy lineage switch, an emergent form of relapse in leukemia

Sara K. Silbert, Alexander W. Rankin, Chloe N. Hoang, Alexandra Semchenkova, Regina M. Myers, Elena Zerkalenkova, Hao-Wei Wang, Alexandra E. Kovach, Constance M. Yuan, Dana Delgado Colon, Loïc Vasseur, Alex Bataller, Samuel John, Kaylyn Utley Lyons, Barbara Friedes, Anna Alonso-Saladrigues, Hisham Abdel-Azim, Estelle Balducci, Ahmed Assim Aljudi, Marie Balsat, D. Nathan Biery, Aghiad Chamdin, Bill H. Chang, Raymund S. Cuevo, Barbara De Moerloose, David S. Dickens, Ulrich Duffner, Nicolas Duployez, Firas El Chaer, Michelle Ann Elliott, Gabriele Escherich, Sneha Fernandes, Mandi R. Fitzjohn, Zhubin Gahvari, Stephan A. Grupp, Rui Rochelle He, Cynthia Harrison, Christopher B. Hergott, Emily M. Hsieh, Annette S. Kim, Dennis J. Kuo, Daniel P. Larson, Benjamin J. Lee, Thibaut Leguay, R. Coleman Lindsley, Abhishek A. Mangaonkar, Kerstin Mezger, Holly L. Pacenta, Jing Pan, Marlie Provost, Latika Puri, Sunil S. Raikar, Armando Martinez, Isabella Bristol, Kyle Murphy, Lauren Reiman, Michele Redell, Kelly Reed, Gabrielle Roth-Guepin, Jeremy Rubinstein, Süreyya Savaşan, Kristian Schafernak, Alexandra Stevens, Aimee Talleur, Naomi Torres Carapia, Jacques Vargaftig, Anant Vatsayan, Matthias Wölfl, Liping Zhao, Susana Rives, Vanessa A. Fabrizio, Koji Sasaki, Ibrahim Aldoss, Nicolas Boissel, Susan R. Rheingold, Kara L. Davis, Sara Ghorashian, Elad Jacoby, Alexander Popov, Adam J. Lamble, Nirali N. Shah

Blood (2025) 146 (4): 437–455.

https://doi.org/10.1182/blood.2024026655

Published: 2025

Includes: Supplemental data

Journal Articles

Itacitinib for the prevention of IEC therapy–associated CRS: results from the 2-part phase 2 INCB 39110-211 study

Matthew J. Frigault, Richard T. Maziarz, Jae H. Park, Aleksandr Lazaryan, Nirav N. Shah, Jakub Svoboda, Lazaros Lekakis, Ran Reshef, Christine L. Phillips, Lea Burke, Jing Lei, Michael Pratta, Rodica Morariu-Zamfir, John F. DiPersio

Blood (2025) 146 (4): 422–436.

https://doi.org/10.1182/blood.2024026586

Published: 2025

Includes: Supplemental data

Journal Articles

Development of ALL-Hematotox: predicting post-CAR T-cell hematotoxicity in B-cell acute lymphoblastic leukemia

Monica S. Nair, Sara K. Silbert, Kai Rejeski, Karilynn A. Wilson, Adam J. Lamble, Yannis Valtis, Bonnie Yates, Alexa Morales Arana, Roni Shouval, Kevin Curran, Rebecca A. Gardner, Haneen Shalabi, Colleen Annesley, Jae H. Park, Marion Subklewe, Nirali N. Shah

Blood (2025) 145 (11): 1136–1148.

https://doi.org/10.1182/blood.2024025910

Published: 2025

Includes: Supplemental data

Journal Articles

How I treat postimmunotherapy relapsed B-ALL

Adam J. Lamble, Alexandra E. Kovach, Nirali N. Shah

Blood (2025) 145 (1): 64–74.

https://doi.org/10.1182/blood.2024024517

Published: 2025

Journal Articles

Lack of Benefit of Autologous Hematopoietic Cell Transplantation (auto-HCT) in Mantle Cell Lymphoma (MCL) Patients (pts) in First Complete Remission (CR) with Undetectable Minimal Residual Disease (uMRD): Initial Report from the ECOG-ACRIN EA4151 Phase 3 Randomized Trial

Blood (2024) 144 (Supplement 2): LBA-6.

https://doi.org/10.1182/blood-2024-212973

Published: 2024

Journal Articles

Rapcabtagene Autoleucel (YTB323) in Patients (Pts) with Relapsed/Refractory Diffuse Large B-Cell Lymphoma (R/R DLBCL): Phase II Trial Clinical Update

Blood (2024) 144 (Supplement 1): 67.

https://doi.org/10.1182/blood-2024-204264

Published: 2024

Journal Articles

A Randomized Phase II Study of Mosunetuzumab SC Plus Polatuzumab Vedotin Demonstrates Improved Outcomes Versus Rituximab Plus Polatuzumab Vedotin in Patients (Pts) with Relapsed or Refractory (R/R) Large B-Cell Lymphoma (LBCL)

Blood (2024) 144 (Supplement 1): 989.

https://doi.org/10.1182/blood-2024-194581

Published: 2024

Journal Articles

Pirtobrutinib in Patients with Mantle Cell Lymphoma: A Real-World Study in the United States

Nirav N. Shah, Katherine B. Winfree, Naleen Raj Bhandari, Qinli Ma, Dan He, Sarang Abhyankar, Lisa M. Hess

Blood (2024) 144 (Supplement 1): 7799.

https://doi.org/10.1182/blood-2024-199667

Published: 2024

Journal Articles

Early Safety and Feasibility Results from a Phase II Trial of De-Escalated Ptcy and Ruxolitinib for Gvhd Prophylaxis in Older Patients Undergoing Reduced Intensity Conditioning Allogeneic HCT

Sameem Abedin, Fateeha Furqan, Lyndsey Runaas, Walter Longo, Nirav N. Shah, Timothy S. Fenske, Marcelo C. Pasquini, William R Drobyski, Xue-Zhong Yu, Mehdi Hamadani

Blood (2024) 144 (Supplement 1): 1039.

https://doi.org/10.1182/blood-2024-200832

Published: 2024

Journal Articles

Clinical Factors Associated with Prolonged Cytopenias after CD19 Chimeric Antigen Receptor T-Cell Therapy for Pediatric B-Cell Acute Lymphoblastic Leukemia

Regina M. Myers, Yimei Li, Adam Lamble, Emily M. Hsieh, Samuel John, Gregory Dolan, Hongyan Liu, Lee Chen, Jennifer Sheppard, Amanda M. DiNofia, Colleen Annesley, Stephan A. Grupp, Deepa Bhojwani, Rebecca A. Gardner, Lia Gore, Susan R Rheingold, Nirali N. Shah, Michael A. Pulsipher

Blood (2024) 144 (Supplement 1): 4827.

https://doi.org/10.1182/blood-2024-202027

Published: 2024

Journal Articles

PAX5 Loss Compromises CD22 Protein Levels and Responses to Inotuzumab Ozogamicin in B-Cell Acute Lymphoblastic Leukemia

Jacinta Davis, JuanCarlos Balandrán, Katharina Hayer, Sisi Zheng, Zhiwei Ang, Evelyn Liu, Bonnie Yates, Nirali N. Shah, Iannis Aifantis, Andrei Thomas-Tikhonenko

Blood (2024) 144 (Supplement 1): 4170.

https://doi.org/10.1182/blood-2024-208185

Published: 2024

Journal Articles

Development of a Novel Humanized BCMA-Directed CAR for Multiple Myeloma: Robust Activity and Low Toxicity in Preclinical Studies

Aalia N. Khan, Jayant S. Goda, Sweety Asija, Atharva Karulkar, Pranoti Palkar, Ambalika Chowdury, Ankesh K. Jaiswal, Deepti Phadnis, Shreshtha Shah, Afrin Firfiray, Juber Pendhari, Pranali Patil, Nirali N. Shah, Manju Sengar, Hasmukh Jain, Rahul Purwar

Blood (2024) 144 (Supplement 1): 4809.

https://doi.org/10.1182/blood-2024-203862

Published: 2024

Journal Articles

Talicabtagene Autoleucel (humanized CD19 CAR-T) As a Second Line Therapy in r/r B-Cell Lymphoma: Sub-Analysis from a Phase I/II Trial

Blood (2024) 144 (Supplement 1): 7203.

https://doi.org/10.1182/blood-2024-201984

Published: 2024

Journal Articles

Ruxolitinib Resistance or Intolerance in Steroid-Refractory Chronic Graft-Versus-Host Disease - a Real-World Single Center Analysis

Gulrayz Ahmed, Amer Al Homssi, Ramsha Ahmed, Walter Longo, Nirav N. Shah, Lyndsey Runaas, Marcelo C. Pasquini, Timothy S. Fenske, Lisa E Rein, Aniko Szabo, Mehdi Hamadani, Sameem Abedin

Blood (2024) 144 (Supplement 1): 7346.

https://doi.org/10.1182/blood-2024-209225

Published: 2024

Journal Articles

Cytogenetic Abnormalities Following CAR T Cell Therapy for B-Cell Malignancies

Na Hyun Kim, Fatima Khamissi, Kathleen Bone, Nathan Kopp, Walter Longo, Bryon D. Johnson, Tyce Kearl, Peiman Hematti, Mehdi Hamadani, Timothy S. Fenske, Nirav N. Shah

Blood (2024) 144 (Supplement 1): 3459.

https://doi.org/10.1182/blood-2024-205752

Published: 2024

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CXCL9 as a novel prognostic marker to identify high-risk adults with hemophagocytic lymphohistiocytosis

Increased Prevalence of Clonal Hematopoiesis in Children with Sickle Cell Disease

Genomic Determinants of Response and Resistance to Pirtobrutinib in Relapsed/Refractory Chronic Lymphocytic Leukemia

Driving CAR-Ts SafeSLE

T-ICAHT: grading and prognostic impact of thrombocytopenia after CAR T-cell therapy

Project EVOLVE: an international analysis of postimmunotherapy lineage switch, an emergent form of relapse in leukemia

Itacitinib for the prevention of IEC therapy–associated CRS: results from the 2-part phase 2 INCB 39110-211 study

Development of ALL-Hematotox: predicting post-CAR T-cell hematotoxicity in B-cell acute lymphoblastic leukemia

How I treat postimmunotherapy relapsed B-ALL

Lack of Benefit of Autologous Hematopoietic Cell Transplantation (auto-HCT) in Mantle Cell Lymphoma (MCL) Patients (pts) in First Complete Remission (CR) with Undetectable Minimal Residual Disease (uMRD): Initial Report from the ECOG-ACRIN EA4151 Phase 3 Randomized Trial

Rapcabtagene Autoleucel (YTB323) in Patients (Pts) with Relapsed/Refractory Diffuse Large B-Cell Lymphoma (R/R DLBCL): Phase II Trial Clinical Update

A Randomized Phase II Study of Mosunetuzumab SC Plus Polatuzumab Vedotin Demonstrates Improved Outcomes Versus Rituximab Plus Polatuzumab Vedotin in Patients (Pts) with Relapsed or Refractory (R/R) Large B-Cell Lymphoma (LBCL)

Pirtobrutinib in Patients with Mantle Cell Lymphoma: A Real-World Study in the United States

Early Safety and Feasibility Results from a Phase II Trial of De-Escalated Ptcy and Ruxolitinib for Gvhd Prophylaxis in Older Patients Undergoing Reduced Intensity Conditioning Allogeneic HCT

Clinical Factors Associated with Prolonged Cytopenias after CD19 Chimeric Antigen Receptor T-Cell Therapy for Pediatric B-Cell Acute Lymphoblastic Leukemia

PAX5 Loss Compromises CD22 Protein Levels and Responses to Inotuzumab Ozogamicin in B-Cell Acute Lymphoblastic Leukemia

Development of a Novel Humanized BCMA-Directed CAR for Multiple Myeloma: Robust Activity and Low Toxicity in Preclinical Studies

Talicabtagene Autoleucel (humanized CD19 CAR-T) As a Second Line Therapy in r/r B-Cell Lymphoma: Sub-Analysis from a Phase I/II Trial

Ruxolitinib Resistance or Intolerance in Steroid-Refractory Chronic Graft-Versus-Host Disease - a Real-World Single Center Analysis

Cytogenetic Abnormalities Following CAR T Cell Therapy for B-Cell Malignancies

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