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Journal Articles

How I treat AML relapse after allogeneic HSCT

Mahasweta Gooptu, H. Moses Murdock, Robert J. Soiffer
Journal: Blood
Blood (2025) 145 (19): 2128–2137.
https://doi.org/10.1182/blood.2024025705
Published: 2025
Journal Articles

Measurable residual disease and posttransplantation gilteritinib maintenance for patients with FLT3-ITD –mutated AML

Clinical Trials & Observations
Mark J. Levis, Mehdi Hamadani, Brent R. Logan, Richard J. Jones, Anurag K. Singh, Mark R. Litzow, John R. Wingard, Esperanza B. Papadopoulos, Alexander E. Perl, Robert J. Soiffer, Celalettin Ustun, Masumi Ueda Oshima, Geoffrey L. Uy, Edmund K. Waller, Sumithira Vasu, Melhem Solh, Asmita Mishra, Lori S. Muffly, Hee-Je Kim, Matthias Stelljes, Yuho Najima, Masahiro Onozawa, Kirsty Thomson, Arnon Nagler, Andrew H. Wei, Guido Marcucci, Caroline Chen, Nahla Hasabou, Matt Rosales, Jason Hill, Stanley C. Gill, Rishita Nuthethi, Denise King, Adam Mendizabal, Steven M. Devine, Mary M. Horowitz, Yi-Bin Chen
Journal: Blood
Blood (2025) 145 (19): 2138–2148.
https://doi.org/10.1182/blood.2024025154
Published: 2025
Includes: Supplemental data
Journal Articles

GATA2 links stemness to chemotherapy resistance in acute myeloid leukemia

Fatemeh Alikarami, Hongbo M. Xie, Simone S. Riedel, Haley T. Goodrow, Declan R. Barrett, Leila Mahdavi, Alexandra Lenard, Changya Chen, Taylor Yamauchi, Etienne Danis, Zhendong Cao, Vu L. Tran, Mabel Minji Jung, Yapeng Li, Hua Huang, Junwei Shi, Kai Tan, David T. Teachey, Emery H. Bresnick, Tobias A. Neff, Kathrin M. Bernt
Journal: Blood
Blood (2025) 145 (19): 2179–2195.
https://doi.org/10.1182/blood.2024025761
Published: 2025
Includes: Supplemental data
Journal Articles

The JAK2 46/1 haplotype influences PD-L1 expression

Brief Report
Gonzalo Carreño-Tarragona, María Tiana, Raquel Rouco, Alejandra Leivas, Jesús Victorino, Roberto García-Vicente, Andrew J. Chase, Andrea Maidana, William J. Tapper, Rosa Ayala, Nicholas C. P. Cross, Joaquín Martínez-López, Miguel Manzanares
Journal: Blood
Blood (2025) 145 (19): 2196–2201.
https://doi.org/10.1182/blood.2023023787
Published: 2025
Includes: Supplemental data
Journal Articles

STING activation improves T-cell-engaging immunotherapy for acute myeloid leukemia

Andreas Linder, Daniel Nixdorf, Niklas Kuhl, Ignazio Piseddu, TengTeng Xu, Anne V. Holtermann, Gunnar Kuut, Rebekka Endres, Nora Philipp, Veit Bücklein, Johann de Graaff, Thomas Carell, Sebastian Kobold, Roman Kischel, Veit Hornung, Marion Subklewe
Journal: Blood
Blood (2025) 145 (19): 2149–2160.
https://doi.org/10.1182/blood.2024026934
Published: 2025
Includes: Supplemental data
Journal Articles

Myelodysplastic neoplasm with biallelic TP53 inactivation in a patient with plasma cell myeloma after cytotoxic therapy

Rong He, Dong Chen
Journal: Blood
Blood (2025) 145 (19): 2230.
https://doi.org/10.1182/blood.2024028288
Published: 2025
Journal Articles

Delineating Mpl-dependent and -independent phenotypes of Jak2 V617F- positive MPNs in vivo

Nicolas Papadopoulos, Audrey Nédélec, Yacine Rahmani, Hosuk Ryou, Jean-Philippe Defour, Jens Rittscher, Daniel Royston, Stefan N. Constantinescu
Journal: Blood
Blood blood.2024026711.
https://doi.org/10.1182/blood.2024026711
Published: 2025
Includes: Supplemental data
Journal Articles

BLAST: A Globally Applicable and Molecularly Versatile Survival Model for Chronic Myelomonocytic Leukemia

Ayalew Tefferi, Saubia Fathima, Maymona Abdelmagid, Ali Alsugair, Fnu Aperna, Mahsa Rezasoltani, Muhammad Yousuf, Anuya Natu, Clifford M Csizmar, Mark Gurney, Terra L Lasho, Christy M. Finke, Rashmi Kanagal-Shamanna, Danielle Hammond, Kelly Sharon Chien, Alexandre Bazinet, Courtney D. DiNardo, Tapan M. Kadia, Abhishek A. Mangaonkar, Naval G. Daver, Animesh D Pardanani, Gautam Borthakur, Cinthya J Zepeda-Mendoza, Kaaren K Reichard, Rong He, Sanam Loghavi, Francesco Passamonti, Farhad Ravandi, Koji Sasaki, Dirk Larson, Guillermo Garcia-Manero, Francesco Onida, Naseema Gangat, Guillermo Montalban-Bravo, Mrinal M. Patnaik
Journal: Blood
Blood blood.2024027170.
https://doi.org/10.1182/blood.2024027170
Published: 2025
Includes: Supplemental data
Journal Articles

Defining 2 biologically and clinically distinct groups in acute leukemia with a mixed phenotype

Pallavi Galera, Deepika Dilip, Andriy Derkach, Alexander Chan, Yanming Zhang, Sonali Persaud, Tanmay Mishra, Kyle Kramer, Mahak Kathpalia, Ying Liu, Christopher Famulare, Qi Gao, Douglas A. Mata, Maria Arcila, Mark B. Geyer, Eytan Stein, Ahmet Dogan, Mikhail Roshal, Ross L. Levine, Jacob Glass, Wenbin Xiao
Journal: Blood
Blood (2025) 145 (18): 2056–2069.
https://doi.org/10.1182/blood.2024026273
Published: 2025
Includes: Supplemental data
Journal Articles

Clinical-genomic profiling of MDS to inform allo-HCT: recommendations from an international panel on behalf of the EBMT

Carmelo Gurnari, Marie Robin, Lionel Adès, Mahmoud Aljurf, Antonio Almeida, Fernando Barroso Duarte, Elsa Bernard, Corey Cutler, Matteo Giovanni Della Porta, Theo De Witte, Amy DeZern, Joanna Drozd-Sokolowska, Eric Duncavage, Pierre Fenaux, Nico Gagelmann, Guillermo Garcia-Manero, Claudia Haferlach, Torsten Haferlach, Robert Hasserjian, Eva Hellström-Lindberg, Meagan Jacoby, Austin Kulasekararaj, R. Coleman Lindsley, Jaroslaw P. Maciejewski, Hideki Makishima, Luca Malcovati, Moshe Mittelman, Anders E. Myhre, Seishi Ogawa, Francesco Onida, Elli Papaemmanuil, Jakob Passweg, Uwe Platzbecker, Lisa Pleyer, Kavita Raj, Valeria Santini, Anna Sureda, Magnus Tobiasson, Maria Teresa Voso, Ibrahim Yakoub-Agha, Amer Zeidan, Matthew Walter, Nicolaus Kröger, Donal P. McLornan, Mario Cazzola
Journal: Blood
Blood (2025) 145 (18): 1987–2001.
https://doi.org/10.1182/blood.2024025131
Published: 2025
Includes: Supplemental data
Journal Articles

Long-term outcomes with single-agent BRAF inhibitor therapy in Erdheim-Chester disease

Clinical Trials & Observations
Gaurav Goyal, Anne S. Reiner, Dana Bossert, Allison M. Sigler, Mario E. Lacouture, Veronica Rotemberg, Jasmine H. Francis, Ronald S. Go, Raajit K. Rampal, Eli L. Diamond
Journal: Blood
Blood (2025) 145 (18): 2100–2103.
https://doi.org/10.1182/blood.2024028032
Published: 2025
Includes: Supplemental data
Journal Articles

How I treat higher-risk MDS

Alain Mina, Rami Komrokji
Journal: Blood
Blood (2025) 145 (18): 2002–2011.
https://doi.org/10.1182/blood.2024025271
Published: 2025
Journal Articles

Common hereditary variants of the APOE gene and posttransplant outcome in acute myeloid leukemia

Clinical Trials & Observations
Julian Ronnacker, Michael Grau, Maximilian Klasmeier, Christian Klesse, Henning Baldauf, Stefan Abert, Andrew F. Berdel, Friederike T. Füsser, Sarah Sandmann, Jörn Albring, Christian Reicherts, Simon Call, Julia Marx, Matthias Floeth, Eva Eßeling, Lina Kolloch, Philipp Berning, Annika Scheller, Klaus Wethmar, Hartmut Schmidt, Bernhard Schlüter, Wolfgang E. Berdel, Benjamin N. Ostendorf, Sohail F. Tavazoie, Jan-Henrik Mikesch, Georg Lenz, Katharina Fleischhauer, Johannes Schetelig, Matthias Stelljes, Christoph Schliemann
Journal: Blood
Blood (2025) 145 (17): 1943–1956.
https://doi.org/10.1182/blood.2024026886
Published: 2025
Includes: Supplemental data
Journal Articles

PSTK inhibition activates cGAS-STING, precipitating ferroptotic cell death in leukemic stem cells

Lingli He, Ting Zhao, Wei Zhong Leong, Azeem Sharda, Christina Mayerhofer, Shenglin Mei, Gracia M. Bonilla, Juan Bautista Menendez-Gonzalez, Karin Gustafsson, Tsuyoshi Fukushima, Trine A. Kristiansen, Ji-Won Lee, Yanxin Xu, Lei Chen, Jun Xia, Luis Angel Orozco, Bogdan Budnik, Ruslan Sadreyev, Zhixun Dou, David B. Sykes, David T. Scadden
Journal: Blood
Blood (2025) 145 (17): 1903–1914.
https://doi.org/10.1182/blood.2024026040
Published: 2025
Includes: Supplemental data
Journal Articles

Venetoclax plus daunorubicin and cytarabine for newly diagnosed acute myeloid leukemia: results of a phase 1b study

Clinical Trials & Observations Brief Report
Ioannis Mantzaris, Mendel Goldfinger, Matan Uriel, Aditi Shastri, Nishi Shah, Kira Gritsman, Noah S. Kornblum, Lauren Shapiro, Roberto Alejandro Sica, Anne Munoz, Nicole Chambers, Aradhika Dhawan, Jhannine Alyssa Verceles, Karen Fehn, Balda Tirone, Lamisha Shah, Shaunmonique Clark, Chenxin Zhang, Mimi Kim, Dennis L. Cooper, Amit Verma, Marina Konopleva, Eric J. Feldman
Journal: Blood
Blood (2025) 145 (17): 1870–1875.
https://doi.org/10.1182/blood.2024026700
Published: 2025
Includes: Supplemental data
Journal Articles

How I diagnose and treat myeloid/lymphoid neoplasms with tyrosine kinase gene fusions

Clinical Trials & Observations
Andreas Reiter, Georgia Metzgeroth, Nicholas C. P. Cross
Journal: Blood
Blood (2025) 145 (16): 1758–1768.
https://doi.org/10.1182/blood.2023022417
Published: 2025
Journal Articles

How I approach the treatment of thrombotic complications in patients with myeloproliferative neoplasms

Alexandre Guy, Pierre-Emmanuel Morange, Chloé James
Journal: Blood
Blood (2025) 145 (16): 1769–1779.
https://doi.org/10.1182/blood.2024025627
Published: 2025
Journal Articles

Early T-precursor acute lymphoblastic leukemia with mature plasmacytoid dendritic cell proliferation

Benjamin Podvin, Adélaïde Hardeman
Journal: Blood
Blood (2025) 145 (16): 1827.
https://doi.org/10.1182/blood.2024028302
Published: 2025
Journal Articles

Introduction to a How I Treat series on myeloproliferative neoplasms

Jason Gotlib
Journal: Blood
Blood (2025) 145 (16): 1707–1709.
https://doi.org/10.1182/blood.2025028401
Published: 2025
Journal Articles

How I treat patients with low-risk polycythemia vera who require cytoreduction

Mary Frances McMullin, Claire N. Harrison
Journal: Blood
Blood (2025) 145 (16): 1717–1723.
https://doi.org/10.1182/blood.2023022418
Published: 2025