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Plerixafor and G-CSF versus placebo and G-CSF to mobilize hematopoietic stem cells for autologous stem cell transplantation in patients with multiple myeloma
Comparable survival between HIV+ and HIV− non-Hodgkin and Hodgkin lymphoma patients undergoing autologous peripheral blood stem cell transplantation
Issue Archive
June 4 2009
In this Issue
Table of Contents
INSIDE BLOOD
BLOOD WORK
PLENARY PAPERS
HOW I TREAT
CLINICAL TRIALS AND OBSERVATIONS
Plerixafor and G-CSF versus placebo and G-CSF to mobilize hematopoietic stem cells for autologous stem cell transplantation in patients with multiple myeloma
Clinical Trials & Observations
John F. DiPersio,Edward A. Stadtmauer,Auayporn Nademanee,Ivana N. M. Micallef,Patrick J. Stiff,Jonathan L. Kaufman,Richard T. Maziarz,Chitra Hosing,Stefan Früehauf,Mitchell Horwitz,Dennis Cooper,Gary Bridger,Gary Calandra,for the 3102 Investigators
GENE THERAPY
HEMATOPOIESIS AND STEM CELLS
Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors
Josette-Renée Landry,Nicolas Bonadies,Sarah Kinston,Kathy Knezevic,Nicola K. Wilson,S. Helen Oram,Mary Janes,Sandie Piltz,Michelle Hammett,Jacinta Carter,Tina Hamilton,Ian J. Donaldson,Georges Lacaud,Jonathan Frampton,George Follows,Valerie Kouskoff,Berthold Göttgens
IMMUNOBIOLOGY
Cytohesin-1 controls the activation of RhoA and modulates integrin-dependent adhesion and migration of dendritic cells
Thomas Quast,Barbara Tappertzhofen,Cora Schild,Jessica Grell,Niklas Czeloth,Reinhold Förster,Ronen Alon,Line Fraemohs,Katrin Dreck,Christian Weber,Tim Lämmermann,Michael Sixt,Waldemar Kolanus
LYMPHOID NEOPLASIA
MYELOID NEOPLASIA
Clinical relevance of Wilms tumor 1 gene mutations in childhood acute myeloid leukemia
Iris H. I. M. Hollink,Marry M. van den Heuvel-Eibrink,Martin Zimmermann,Brian V. Balgobind,Susan T. C. J. M. Arentsen-Peters,Marielle Alders,Andre Willasch,Gertjan J. L. Kaspers,Jan Trka,Andre Baruchel,Siebold S. N. de Graaf,Ursula Creutzig,Rob Pieters,Dirk Reinhardt,C. Michel Zwaan
RED CELLS, IRON, AND ERYTHROPOIESIS
THROMBOSIS AND HEMOSTASIS
TRANSFUSION MEDICINE
TRANSPLANTATION
Invariant natural killer T cell–natural killer cell interactions dictate transplantation outcome after α-galactosylceramide administration
Rachel D. Kuns,Edward S. Morris,Kelli P. A. MacDonald,Kate A. Markey,Helen M. Morris,Neil C. Raffelt,Tatjana Banovic,Alistair L. J. Don,Vanessa Rowe,Angela C. Burman,Andrew D. Clouston,Camile Farah,Gurdyal S. Besra,Petr A. Illarionov,Mark J. Smyth,Steven A. Porcelli,Geoffrey R. Hill
Comparable survival between HIV+ and HIV− non-Hodgkin and Hodgkin lymphoma patients undergoing autologous peripheral blood stem cell transplantation
Brief Report
José L. Díez-Martín,Pascual Balsalobre,Alessandro Re,Mariagrazia Michieli,José M. Ribera,Carmen Canals,Eulogio Conde,Anne Rosselet,Ian Gabriel,Rosario Varela,Bernardino Allione,Kate Cwynarski,Philippe Genet,Ildefonso Espigado,Pierre Biron,Norbert Schmitz,Anne E. Hunter,Augustin Ferrant,Gaelle Guillerm,Mark Hentrich,Manuel Jurado,Pascual Fernández,David Serrano,Giuseppe Rossi,Anna Sureda,on behalf of the European Group for Blood and Marrow Transplantation Lymphoma Working Party
VASCULAR BIOLOGY
The 15(S)-hydroxyeicosatetraenoic acid-induced angiogenesis requires Janus kinase 2-signal transducer and activator of transcription-5B–dependent expression of interleukin-8
Sergey Y. Cheranov,Dong Wang,Venkatesh Kundumani-Sridharan,Manjula Karpurapu,Qiuhua Zhang,Koteswara R. Chava,Gadiparthi N. Rao
CORRESPONDENCE
APO866 activity in hematologic malignancies: a preclinical in vitro study
Michele Cea,Gabriele Zoppoli,Santina Bruzzone,Floriana Fruscione,Eva Moran,Anna Garuti,Ilaria Rocco,Gabriella Cirmena,Salvatore Casciaro,Francesca Olcese,Ivana Pierri,Antonia Cagnetta,Fabio Ferrando,Riccardo Ghio,Marco Gobbi,Alberto Ballestrero,Franco Patrone,Alessio Nencioni
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Cover Image
Cover Image
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Dendritic cell migration requires polarity and coordinated actin dynamics (represented in pseudo colors) at the cell front for chemotactic migration on 2-dimensional surfaces (first row) and 3-dimensional environments (second row). Loss of the small GTPase Cdc42 results in uncoordinated leading edge dynamics that mildly impairs migration on 2-dimensional (third row), but completely blocks locomotion in 3-dimensional (fourth row) and in vivo. See the article by Lämmermann et al on page 5703.
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