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Issue Archive

Volume 125, Issue 21
May 21 2015
Issue Cover

Table of Contents

INSIDE BLOOD COMMENTARIES

INSIDE BLOOD COMMENTARY
A spoonful of sugar helps lymphoma cells go up
Nicholas Chiorazzi
View Articletitled, A spoonful of sugar helps lymphoma cells go up
INSIDE BLOOD COMMENTARY
Pregnancy in sickle cell disease is at very high risk
Mariane de Montalembert,Catherine Deneux-Tharaux
View Articletitled, Pregnancy in sickle cell disease is at very high risk
INSIDE BLOOD COMMENTARY
Special delivery for ADAMTS13
Karl Desch
View Articletitled, Special delivery for ADAMTS13
INSIDE BLOOD COMMENTARY
B7-H3 ameliorates GVHD
Peter Steinberger
View Articletitled, B7-H3 ameliorates GVHD

PERSPECTIVES

The role of rituximab in adults with warm antibody autoimmune hemolytic anemia
Daan Dierickx,Alain Kentos,André Delannoy
View Articletitled, The role of rituximab in adults with warm antibody autoimmune hemolytic anemia

BLOOD SPOTLIGHT

The role of stem cell transplantation for chronic myelogenous leukemia in the 21st century
Clinical Trials & Observations
A. John Barrett,Sawa Ito
View Articletitled, The role of stem cell transplantation for chronic myelogenous leukemia in the 21st century

REVIEW ARTICLE

Secondary mutations as mediators of resistance to targeted therapy in leukemia
Naval Daver,Jorge Cortes,Farhad Ravandi,Keyur P. Patel,Jan A. Burger,Marina Konopleva,Hagop Kantarjian
View Articletitled, Secondary mutations as mediators of resistance to targeted therapy in leukemia
Supplemental data

HOW I TREAT

How I treat hyperleukocytosis in acute myeloid leukemia
Christoph Röllig,Gerhard Ehninger
View Articletitled, How I treat hyperleukocytosis in acute myeloid leukemia

CLINICAL TRIALS AND OBSERVATIONS

Eculizumab reduces complement activation, inflammation, endothelial damage, thrombosis, and renal injury markers in aHUS
Clinical Trials & Observations
Roxanne Cofiell,Anjli Kukreja,Krystin Bedard,Yan Yan,Angela P. Mickle,Masayo Ogawa,Camille L. Bedrosian,Susan J. Faas
View Articletitled, Eculizumab reduces complement activation, inflammation, endothelial damage, thrombosis, and renal injury markers in aHUS
Supplemental data

HEMATOPOIESIS AND STEM CELLS

The aryl hydrocarbon receptor nuclear translocator is an essential regulator of murine hematopoietic stem cell viability
Bryan L. Krock,Tzipora S. Eisinger-Mathason,Dionysios N. Giannoukos,Jessica E. Shay,Mercy Gohil,David S. Lee,Michael S. Nakazawa,Julie Sesen,Nicolas Skuli,M. Celeste Simon
View Articletitled, The aryl hydrocarbon receptor nuclear translocator is an essential regulator of murine hematopoietic stem cell viability
Supplemental data
Antagonism between MCL-1 and PUMA governs stem/progenitor cell survival during hematopoietic recovery from stress
Alex R. D. Delbridge,Joseph T. Opferman,Stephanie Grabow,Andreas Strasser
View Articletitled, Antagonism between MCL-1 and PUMA governs stem/progenitor cell survival during hematopoietic recovery from stress
Supplemental data

IMMUNOBIOLOGY

Hereditary systemic immunoglobulin light-chain amyloidosis
Merrill D. Benson,Juris J. Liepnieks,Barbara Kluve-Beckerman
View Articletitled, Hereditary systemic immunoglobulin light-chain amyloidosis

LYMPHOID NEOPLASIA

Lectins from opportunistic bacteria interact with acquired variable-region glycans of surface immunoglobulin in follicular lymphoma
Dunja Schneider,Marcus Dühren-von Minden,Alabbas Alkhatib,Corinna Setz,Cornelis A. M. van Bergen,Marco Benkißer-Petersen,Isabel Wilhelm,Sarah Villringer,Sergey Krysov,Graham Packham,Katja Zirlik,Winfried Römer,Christian Buske,Freda K. Stevenson,Hendrik Veelken,Hassan Jumaa
View Articletitled, Lectins from opportunistic bacteria interact with acquired variable-region glycans of surface immunoglobulin in follicular lymphoma
Supplemental data
Characterization of CLL exosomes reveals a distinct microRNA signature and enhanced secretion by activation of BCR signaling
Yuh-Ying Yeh,Hatice Gulcin Ozer,Amy M. Lehman,Kami Maddocks,Lianbo Yu,Amy J. Johnson,John C. Byrd
View Articletitled, Characterization of CLL exosomes reveals a distinct microRNA signature and enhanced secretion by activation of BCR signaling
Supplemental data

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

GATA2 is critical for the maintenance of cellular identity in differentiated mast cells derived from mouse bone marrow
Shin’ya Ohmori,Takashi Moriguchi,Yuki Noguchi,Muneharu Ikeda,Kota Kobayashi,Nazuki Tomaru,Yasushi Ishijima,Osamu Ohneda,Masayuki Yamamoto,Kinuko Ohneda
View Articletitled, GATA2 is critical for the maintenance of cellular identity in differentiated mast cells derived from mouse bone marrow
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Adverse maternal and perinatal outcomes in pregnant women with sickle cell disease: systematic review and meta-analysis
Clinical Trials & Observations
Eugene Oteng-Ntim,Daveena Meeks,Paul T. Seed,Louise Webster,Jo Howard,Pat Doyle,Lucy C. Chappell
View Articletitled, Adverse maternal and perinatal outcomes in pregnant women with sickle cell disease: systematic review and meta-analysis

THROMBOSIS AND HEMOSTASIS

Platelet-delivered ADAMTS13 inhibits arterial thrombosis and prevents thrombotic thrombocytopenic purpura in murine models
Brandy Pickens,Yingying Mao,Dengju Li,Don L. Siegel,Mortimer Poncz,Douglas B. Cines,X. Long Zheng
View Articletitled, Platelet-delivered ADAMTS13 inhibits arterial thrombosis and prevents thrombotic thrombocytopenic purpura in murine models
Supplemental data

TRANSPLANTATION

B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality
Rachelle G. Veenstra,Ryan Flynn,Katharina Kreymborg,Cameron McDonald-Hyman,Asim Saha,Patricia A. Taylor,Mark J. Osborn,Angela Panoskaltsis-Mortari,Annette Schmitt-Graeff,Elisabeth Lieberknecht,William J. Murphy,Jonathan S. Serody,David H. Munn,Gordon J. Freeman,James P. Allison,Tak W. Mak,Marcel van den Brink,Robert Zeiser,Bruce R. Blazar
View Articletitled, B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality
Supplemental data
Impact of allogeneic stem cell transplantation on survival of patients less than 65 years of age with primary myelofibrosis
CME Clinical Trials & Observations Brief Report
Nicolaus Kröger,Toni Giorgino,Bart L. Scott,Markus Ditschkowski,Haefaa Alchalby,Francisco Cervantes,Alessandro Vannucchi,Mario Cazzola,Enrica Morra,Tatjana Zabelina,Margherita Maffioli,Arturo Pereira,Dietrich Beelen,H. Joachim Deeg,Francesco Passamonti
View Articletitled, Impact of allogeneic stem cell transplantation on survival of patients less than 65 years of age with primary myelofibrosis

BLOOD WORK

Parvovirus B19 diagnosed by bone marrow biopsy
Chezi Ganzel,Reinus Constantin
View Articletitled, Parvovirus B19 diagnosed by bone marrow biopsy

CORRESPONDENCE

JAK2V617F complete molecular remission in polycythemia vera/essential thrombocythemia patients treated with ruxolitinib
Clinical Trials & Observations
Lisa Pieri,Alessandro Pancrazzi,Annalisa Pacilli,Claudia Rabuzzi,Giada Rotunno,Tiziana Fanelli,Paola Guglielmelli,Rajmonda Fjerza,Chiara Paoli,Srdan Verstovsek,Alessandro M. Vannucchi
View Articletitled, <em>JAK2</em>V617F complete molecular remission in polycythemia vera/essential thrombocythemia patients treated with ruxolitinib
Maintenance rituximab every 2 months is more toxic than every 3 months in patients with non-Hodgkin lymphoma
Clinical Trials & Observations
Armin Rashidi,Eunhye Oak,Nancy L. Bartlett
View Articletitled, Maintenance rituximab every 2 months is more toxic than every 3 months in patients with non-Hodgkin lymphoma
Supplemental data
No association between the presence of killer-cell immunoglobulin-like receptor genes and susceptibility to childhood ALL
Lena Oevermann,Matthias Firnkorn,Sebastian Michaelis,Simon Müller,Elke Schaeffeler,Martin Schrappe,Gunnar Cario,Martin Stanulla,Matthias Schwab,Rupert Handgretinger,Markus Mezger
View Articletitled, No association between the presence of killer-cell immunoglobulin-like receptor genes and susceptibility to childhood ALL
Lenalidomide, idelalisib, and rituximab are unacceptably toxic in patients with relapsed/refractory indolent lymphoma
Chan Yoon Cheah,Loretta J. Nastoupil,Sattva S. Neelapu,Sheryl G. Forbes,Yasuhiro Oki,Nathan H. Fowler
View Articletitled, Lenalidomide, idelalisib, and rituximab are unacceptably toxic in patients with relapsed/refractory indolent lymphoma
Impact of hospital volume on outcomes of patients undergoing chemotherapy for acute myeloid leukemia: a matched cohort study
Smith Giri,Ranjan Pathak,Madan Raj Aryal,Paras Karmacharya,Vijaya Raj Bhatt,Mike G. Martin
View Articletitled, Impact of hospital volume on outcomes of patients undergoing chemotherapy for acute myeloid leukemia: a matched cohort study
Insights from response to tyrosine kinase inhibitor therapy in a rare myeloproliferative neoplasm with CALR mutation and BCR-ABL1
Sanam Loghavi,Naveen Pemmaraju,Rashmi Kanagal-Shamanna,Meenakshi Mehrotra,L. Jeffrey Medeiros,Raja Luthra,Pei Lin,Yang Huh,Hagop M. Kantarjian,Jorge E. Cortes,Srdan Verstovsek,Keyur P. Patel
View Articletitled, Insights from response to tyrosine kinase inhibitor therapy in a rare myeloproliferative neoplasm with <em>CALR</em> mutation and <em>BCR-ABL1</em>

CONTINUING MEDICAL EDUCATION (CME) QUESTIONS

Transplant vs nontransplant in PMF
CME
View Articletitled, Transplant vs nontransplant in PMF
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