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The impact on outcome of the addition of all-trans retinoic acid to intensive chemotherapy in younger patients with nonacute promyelocytic acute myeloid leukemia: overall results and results in genotypic subgroups defined by mutations in NPM1, FLT3, and CEBPA
SNP array analysis of tyrosine kinase inhibitor-resistant chronic myeloid leukemia identifies heterogeneous secondary genomic alterations
Issue Archive
February 4 2010
In this Issue
Table of Contents
INSIDE BLOOD
BLOOD WORK
PLENARY PAPERS
Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients
Helen E. Heslop,Karen S. Slobod,Martin A. Pule,Gregory A. Hale,Alexandra Rousseau,Colton A. Smith,Catherine M. Bollard,Hao Liu,Meng-Fen Wu,Richard J. Rochester,Persis J. Amrolia,Julia L. Hurwitz,Malcolm K. Brenner,Cliona M. Rooney
REVIEW ARTICLES
CLINICAL TRIALS AND OBSERVATIONS
The impact on outcome of the addition of all-trans retinoic acid to intensive chemotherapy in younger patients with nonacute promyelocytic acute myeloid leukemia: overall results and results in genotypic subgroups defined by mutations in NPM1, FLT3, and CEBPA
Clinical Trials & Observations
Alan K. Burnett,Robert K. Hills,Claire Green,Sarah Jenkinson,Kenneth Koo,Yashma Patel,Carol Guy,Amanda Gilkes,Donald W. Milligan,Anthony H. Goldstone,Archibald G. Prentice,Keith Wheatley,David C. Linch,Rosemary E. Gale
HEMATOPOIESIS AND STEM CELLS
IMMUNOBIOLOGY
Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells
Katia Basso,Masumichi Saito,Pavel Sumazin,Adam A. Margolin,Kai Wang,Wei-Keat Lim,Yukiko Kitagawa,Christof Schneider,Mariano J. Alvarez,Andrea Califano,Riccardo Dalla-Favera
LYMPHOID NEOPLASIA
Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group
Libi Hertzberg,Elena Vendramini,Ithamar Ganmore,Gianni Cazzaniga,Maike Schmitz,Jane Chalker,Ruth Shiloh,Ilaria Iacobucci,Chen Shochat,Sharon Zeligson,Gunnar Cario,Martin Stanulla,Sabine Strehl,Lisa J. Russell,Christine J. Harrison,Beat Bornhauser,Akinori Yoda,Gideon Rechavi,Dani Bercovich,Arndt Borkhardt,Helena Kempski,Geertruy te Kronnie,Jean-Pierre Bourquin,Eytan Domany,Shai Izraeli
Association of high-level MCL-1 expression with in vitro and in vivo prednisone resistance in MLL-rearranged infant acute lymphoblastic leukemia
Ronald W. Stam,Monique L. Den Boer,Pauline Schneider,Jasper de Boer,Jill Hagelstein,Maria G. Valsecchi,Paola de Lorenzo,Stephen E. Sallan,Hugh J. M. Brady,Scott A. Armstrong,Rob Pieters
Molecular signatures to improve diagnosis in peripheral T-cell lymphoma and prognostication in angioimmunoblastic T-cell lymphoma
Javeed Iqbal,Dennis D. Weisenburger,Timothy C. Greiner,Julie M. Vose,Timothy McKeithan,Can Kucuk,Huimin Geng,Karen Deffenbacher,Lynette Smith,Karen Dybkaer,Shigeo Nakamura,Masao Seto,Jan Delabie,Francoise Berger,Florence Loong,Wing Y. Au,Young-Hyeh Ko,Ivy Sng,James Olen Armitage,Wing C. Chan,for the International Peripheral T-Cell Lymphoma Project
MYELOID NEOPLASIA
Induction of myeloproliferative disorder and myelofibrosis by thrombopoietin receptor W515 mutants is mediated by cytosolic tyrosine 112 of the receptor
Christian Pecquet,Judith Staerk,Ronan Chaligné,Valerie Goss,Kimberly A. Lee,Xiaowu Zhang,John Rush,Joanne Van Hees,Hélène A. Poirel,Jean-Marie Scheiff,William Vainchenker,Stéphane Giraudier,Roberto D. Polakiewicz,Stefan N. Constantinescu
SNP array analysis of tyrosine kinase inhibitor-resistant chronic myeloid leukemia identifies heterogeneous secondary genomic alterations
Brief Report
Daniel Nowak,Seishi Ogawa,Markus Müschen,Motohiro Kato,Norihiko Kawamata,Antonie Meixel,Verena Nowak,Han S. Kim,Sharon Kang,Ronald Paquette,Mi-Sook Chang,Nils H. Thoennissen,Max Mossner,Wolf-Karsten Hofmann,Alexander Kohlmann,Tamara Weiss,Torsten Haferlach,Claudia Haferlach,H. Phillip Koeffler
PLATELETS AND THROMBOPOIESIS
The contribution of cyclooxygenase-1 and -2 to persistent thromboxane biosynthesis in aspirin-treated essential thrombocythemia: implications for antiplatelet therapy
Alfredo Dragani,Silvia Pascale,Antonio Recchiuti,Domenico Mattoscio,Stefano Lattanzio,Giovanna Petrucci,Luciana Mucci,Elisabetta Ferrante,Aida Habib,Franco O. Ranelletti,Giovanni Ciabattoni,Giovanni Davì,Carlo Patrono,Bianca Rocca
RED CELLS, IRON, AND ERYTHROPOIESIS
THROMBOSIS AND HEMOSTASIS
TRANSPLANTATION
Short-term inhibition of p53 combined with keratinocyte growth factor improves thymic epithelial cell recovery and enhances T-cell reconstitution after murine bone marrow transplantation
Ryan M. Kelly,Emily M. Goren,Patricia A. Taylor,Scott N. Mueller,Heather E. Stefanski,Mark J. Osborn,Hamish S. Scott,Elena A. Komarova,Andrei V. Gudkov,Georg A. Holländer,Bruce R. Blazar
A phase II pilot study of tacrolimus/sirolimus GVHD prophylaxis for sibling donor hematopoietic stem cell transplantation using 3 conditioning regimens
Roberto Rodriguez,Ryotaro Nakamura,Joycelynne M. Palmer,Pablo Parker,Sepideh Shayani,Auyaporn Nademanee,David Snyder,Vinod Pullarkat,Neil Kogut,Joseph Rosenthal,Eileen Smith,Chatchada Karanes,Margaret O'Donnell,Amrita Y. Krishnan,David Senitzer,Stephen J. Forman
CORRESPONDENCE
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Cover Image
Cover Image
![issue cover]()
The stromal vascular fraction (SVF) derived from adipose tissue contains functional hematopoietic stem and progenitor cells (HSPCs) capable of differentiating into a variety of hematopoietic lineages in recipient mice. The image shows adipose tissue containing a high density of Sca-1+ (red) and CD45+ (green) cells, surrounding PECAM-1+ (blue) blood vessels. Adipose tissue could be an alternative source for obtaining functional and transplantable HSPCs. See the article by Han et al on page 957.
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