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Courtney D. Dinardo
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Journal Articles

Genetic risk classification for adults with AML receiving less-intensive therapies: the 2024 ELN recommendations

Hartmut Döhner, Courtney D. DiNardo, Frederick R. Appelbaum, Charles Craddock, Hervé Dombret, Benjamin L. Ebert, Pierre Fenaux, Lucy A. Godley, Robert P. Hasserjian, Richard A. Larson, Ross L. Levine, Yasushi Miyazaki, Dietger Niederwieser, Gert Ossenkoppele, Christoph Röllig, Jorge Sierra, Eytan M. Stein, Martin S. Tallman, Hwei-Fang Tien, Jianxiang Wang, Agnieszka Wierzbowska, Andrew H. Wei, Bob Löwenberg
Journal: Blood
Blood (2024) 144 (21): 2169–2173.
https://doi.org/10.1182/blood.2024025409
Published: 2024
Journal Articles

Genetic risk stratification and outcomes among treatment-naive patients with AML treated with venetoclax and azacitidine

CME Clinical Trials & Observations
Hartmut Döhner, Keith W. Pratz, Courtney D. DiNardo, Andrew H. Wei, Brian A. Jonas, Vinod A. Pullarkat, Michael J. Thirman, Christian Récher, Andre C. Schuh, Sunil Babu, Xiaotong Li, Grace Ku, Zihuan Liu, Yan Sun, Jalaja Potluri, Monique Dail, Brenda Chyla, Daniel A. Pollyea
Journal: Blood
Blood (2024) 144 (21): 2211–2222.
https://doi.org/10.1182/blood.2024024944
Published: 2024
Includes: Supplemental data
Journal Articles

Preclinical efficacy of CDK7 inhibitor-based combinations against myeloproliferative neoplasms transformed to AML

Warren Fiskus, Christopher P Mill, Prithviraj Bose, Lucia Masarova, Naveen Pemmaraju, Andrew Dunbar, Christine Birdwell, John A Davis, Kaberi Das, Hanxi Hou, Taghi Manshouri, Antrix Jain, Anna Malovannaya, Kevin Philip, Noor Alhamadani, Alicia Matthews, Katie Lin, Lauren Flores, Sanam Loghavi, Courtney D. DiNardo, Xiaoping Su, Raajit K. Rampal, Kapil N Bhalla
Journal: Blood
Blood blood.2024026388.
https://doi.org/10.1182/blood.2024026388
Published: 2024
Includes: Supplemental data
Journal Articles

Clonal landscape and clinical outcomes of telomere biology disorders: somatic rescuing and cancer mutations

Fernanda Gutierrez-Rodrigues, Emma M Groarke, Natthakan Thongon, Juan Jose Rodriguez-Sevilla, Luiz Fernando Bazzo Catto, Marena Rebekka Niewisch, Ruba N Shalhoub, Lisa J. McReynolds, Diego V Clé, Bhavisha A. Patel, Xiaoyang Ma, Dalton Hironaka, Flavia S Donaires, Nina R Spitofsky, Barbara A. Santana, Tsung-Po Lai, Lemlem Alemu, Sachiko Kajigaya, Ivana Darden, Weiyin Zhou, Paul V. Browne, Subrata Paul, Justin Lack, David J. Young, Courtney D. DiNardo, Abraham Aviv, Feiyang Ma, Michel Michels de Oliveira, Ana Paula de Azambuja, Cynthia E. Dunbar, Malgorzata Olszewska, Emmanuel Olivier, Eirini P Papapetrou, Neelam Giri, Blanche P. Alter, Carmem M.S. Bonfim, Colin O. Wu, Guillermo Garcia-Manero, Sharon A Savage, Neal S. Young, Simona Colla, Rodrigo T. Calado
Journal: Blood
Blood blood.2024025023.
https://doi.org/10.1182/blood.2024025023
Published: 2024
Includes: Supplemental data
Journal Articles

BRG1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or menin inhibitor

Warren Fiskus, Jessica Piel, Mike Collins, Murphy Hentemann, Branko Cuglievan, Christopher P. Mill, Christine E. Birdwell, Kaberi Das, John A. Davis, Hanxi Hou, Antrix Jain, Anna Malovannaya, Tapan M. Kadia, Naval Daver, Koji Sasaki, Koichi Takahashi, Danielle Hammond, Patrick K. Reville, Jian Wang, Sanam Loghavi, Rwik Sen, Xinjia Ruan, Xiaoping Su, Lauren B. Flores, Courtney D. DiNardo, Kapil N. Bhalla
Journal: Blood
Blood (2024) 143 (20): 2059–2072.
https://doi.org/10.1182/blood.2023022832
Published: 2024
Includes: Supplemental data
Journal Articles

Venetoclax abrogates the prognostic impact of splicing factor gene mutations in newly diagnosed acute myeloid leukemia

Clinical Trials & Observations
Jayastu Senapati, Samuel Urrutia, Sanam Loghavi, Nicholas J. Short, Ghayas C. Issa, Abhishek Maiti, Hussein A. Abbas, Naval G. Daver, Naveen Pemmaraju, Sherry Pierce, Kelly S. Chien, Koji Sasaki, Tapan M. Kadia, Danielle E. Hammond, Gautam Borthakur, Keyur Patel, Farhad Ravandi, Hagop M. Kantarjian, Guillermo Garcia-Manero, Courtney D. DiNardo
Journal: Blood
Blood (2023) 142 (19): 1647–1657.
https://doi.org/10.1182/blood.2023020649
Published: 2023
Includes: Supplemental data
Journal Articles

A Phase 2 Study of the Fully Oral Combination of ASTX727 (Decitabine/Cedazuridine) Plus Venetoclax for Older and/or Unfit Patients with Acute Myeloid Leukemia

Alexandre Bazinet, Guillermo Garcia-Manero, Nicholas J. Short, Yesid Alvarado Valero, Tareq Abuasab, Md Rabiul Islam, Kathryn Montalbano, Ghayas C. Issa, Abhishek Maiti, Musa Yilmaz, Nitin Jain, Lucia Masarova, Steven M. Kornblau, Elias Jabbour, Guillermo Montalban-Bravo, Sherry Pierce, Courtney D. DiNardo, Tapan M. Kadia, Naval Daver, Marina Y. Konopleva, Hagop M. Kantarjian, Farhad Ravandi
Journal: Blood
Blood (2023) 142 (Supplement 1): 833.
https://doi.org/10.1182/blood-2023-172658
Published: 2023
Journal Articles

Phase I/II Study of Quizartinib, Venetoclax, and Decitabine Triple Combination in FLT3-ITD Mutated AML

Musa Yilmaz, Muharrem Muftuoglu, Courtney D. DiNardo, Tapan M. Kadia, Marina Y. Konopleva, Gautam Borthakur, Naveen Pemmaraju, Nicholas J. Short, Yesid Alvarado Valero, Abhishek Maiti, Lucia Masarova, Guillermo Montalban-Bravo, Carissa Jurisprudencia, Allison Pike, Sanam Loghavi, Keyur P. Patel, Guilin Tang, Jairo Matthews, Steven M. Kornblau, Elias Jabbour, Guillermo Garcia-Manero, Farhad Ravandi, Michael Andreeff, Naval Daver
Journal: Blood
Blood (2023) 142 (Supplement 1): 158.
https://doi.org/10.1182/blood-2023-186699
Published: 2023
Journal Articles

Phase II Trial of 10-Day ASTX727 (Decitabine/Cedazuridine) with Venetoclax for Relapsed or Refractory Acute Myeloid Leukemia

Abhishek Maiti, Courtney D. DiNardo, Maro Ohanian, Naval Daver, Gautam Borthakur, Kelly S. Chien, Ghayas C. Issa, Koichi Takahashi, Lucia Masarova, Yesid Alvarado Valero, Elias Jabbour, William G. Wierda, Nicholas J. Short, Melissa MacFarland, Allison Pike, Tapan M. Kadia, Farhad Ravandi, Hagop M. Kantarjian, Guillermo Garcia-Manero, Marina Y. Konopleva
Journal: Blood
Blood (2023) 142 (Supplement 1): 4289.
https://doi.org/10.1182/blood-2023-182901
Published: 2023
Journal Articles

Early Results of the Phase I/II Study Investigating the All-Oral Combination of the Menin Inhibitor Revumenib (SNDX-5613) with Decitabine/Cedazuridine (ASTX727) and Venetoclax in Acute Myeloid Leukemia (SAVE)

Ghayas C. Issa, Branko Cuglievan, Courtney D. DiNardo, Nicholas J. Short, David McCall, Amber Gibson, Cesar Nunez, Miriam B. Garcia, Michael Roth, Aram Bidikian, Allison Pike, Sheila Tan, Brianna Kammerer, Musa Yilmaz, Tapan M. Kadia, Naveen Pemmaraju, Maro Ohanian, Naval Daver, Elias Jabbour, Gautam Borthakur, Farhad Ravandi, Guillermo Garcia-Manero, Michael Andreeff, Hagop M. Kantarjian
Journal: Blood
Blood (2023) 142 (Supplement 1): 58.
https://doi.org/10.1182/blood-2023-182337
Published: 2023
Journal Articles

Uproleselan Added to Cladribine Plus Low Dose Cytarabine (LDAC) in Patients with Treated Secondary Acute Myeloid Leukemia (TS-AML)

Emmanuel Almanza Huante, Alex Bataller, Danielle E. Hammond, Kelly S. Chien, Courtney D. DiNardo, Nicholas J. Short, Abhishek Maiti, Guillermo Montalban-Bravo, Farhad Ravandi, Guillermo Garcia-Manero, Tapan M. Kadia
Journal: Blood
Blood (2023) 142 (Supplement 1): 2922.
https://doi.org/10.1182/blood-2023-185191
Published: 2023
Journal Articles

Clinical and Molecular Characterization of Patients with Therapy Related Myeloid Neoplasms (TRMN)

Oriol Calvete, Julia Mestre, Guillermo Montalban-Bravo, Koji Sasaki, Courtney D. DiNardo, Ana Manzanares, Pamela Acha, Blanca Xicoy, Lurdes Zamora, Isabel Granada, Alvaro Diaz-Gonzalez, Esperanza Such, Laura Palomo, Maria Julia Montoro, Sara García, Leonor Arenillas, David Valcarcel Ferreiras, Andres Jerez, Maria Diez-Campelo, Felipe Prosper, Hui Yang, Carlos E. Bueso-Ramos, Guillermo Garcia-Manero, Francesc Sole, Rashmi Kanagal-Shamanna
Journal: Blood
Blood (2023) 142 (Supplement 1): 3224.
https://doi.org/10.1182/blood-2023-188701
Published: 2023
Journal Articles

A Phase II Study of Vibecotamab, a CD3-CD123 Bispecific T-Cell Engaging Antibody, for MDS or CMML after Hypomethylating Failure and in MRD-Positive AML

Daniel Nguyen, Farhad Ravandi, Sa A. Wang, Jeffrey L. Jorgensen, Wei Wang, Kelly S. Chien, Guillermo Montalban-Bravo, Ghayas C. Issa, Abhishek Maiti, Yesid Alvarado Valero, Naval Daver, Courtney D. DiNardo, Elias Jabbour, Tapan M. Kadia, Naveen Pemmaraju, Musa Yilmaz, Jaehyun Lee, Pavan Bachireddy, Uday R. Popat, Guillermo Garcia-Manero, Hagop M. Kantarjian, Nicholas J. Short
Journal: Blood
Blood (2023) 142 (Supplement 1): 322.
https://doi.org/10.1182/blood-2023-190693
Published: 2023
Journal Articles

Venetoclax (VEN) Improves Response Rates but Not Survival in Patients with Chronic Myelomonocytic Leukemia (CMML) Treated with Hypomethylating Agents (HMA): A Multicenter, Propensity Score Analysis

Douglas Tremblay, Clifford M Csizmar, Courtney D. DiNardo, Somedeb Ball, Noa Rippel, Danielle E. Hammond, Tapan M. Kadia, Farhad Ravandi, Kelly S. Chien, Grace Van Hyfte, Antoine Saliba, Abhishek A Mangaonkar, Terra L Lasho, Aref Al-Kali, Marina Kremyanskaya, Jonathan Feld, Lewis R Silverman, Rami S. Komrokji, John Mascarenhas, Eric Padron, Guillermo Garcia-Manero, David A Sallman, Mrinal M. Patnaik, Guillermo Montalban-Bravo
Journal: Blood
Blood (2023) 142 (Supplement 1): 321.
https://doi.org/10.1182/blood-2023-181795
Published: 2023
Journal Articles

Phase 2 Study of CPX-351 in Combination with Venetoclax in Patients with Newly Diagnosed, High Risk Acute Myeloid Leukemia

Wei-Ying Jen, Courtney D. DiNardo, Kelly S. Chien, Yesid Alvarado-Valero, Lucia Masarova, Mark Brandt, Debra Bull-Linderman, Naval Daver, Guillermo Montalban-Bravo, Alex Bataller, Guillermo Garcia-Manero, Ghayas C. Issa, Amin Alousi, Nicholas J. Short, Farhad Ravandi, Tapan M. Kadia
Journal: Blood
Blood (2023) 142 (Supplement 1): 4273.
https://doi.org/10.1182/blood-2023-182969
Published: 2023
Journal Articles

Molecular Measurable Residual Disease in Patients with Newly Diagnosed m IDH1 Acute Myeloid Leukemia Treated with Ivosidenib + Azacitidine

Courtney D. DiNardo, Dylan Marchione, Michael Heuser, Jianan Hui, Diego Gianolio, Scott Daigle, Sung Choe, Prapti Patel, Stephane De Botton, Hartmut Dohner
Journal: Blood
Blood (2023) 142 (Supplement 1): 4305.
https://doi.org/10.1182/blood-2023-180549
Published: 2023
Journal Articles

Preclinical Studies Demonstrating Efficacy of Tasquinimod in Models of Advanced Myeloproliferative Neoplasm (MPN) in Blastic Phase

Warren C. Fiskus, Lucia Masarova, Christopher Peter Mill, Christine Birdwell, Kaberi Das, John Davis, Hanxi Hou, Noor Alhamadani, Kevin Philip, Alicia Matthews, Taghi Manshouri, Tapan M. Kadia, Courtney D. DiNardo, Prithviraj Bose, Naveen Pemmaraju, Sanam Loghavi, Marie Törngren, Kapil N. Bhalla
Journal: Blood
Blood (2023) 142 (Supplement 1): 741.
https://doi.org/10.1182/blood-2023-185031
Published: 2023
Journal Articles

PPARG and ASS1: Targets of Metabolic Alteration in Venetoclax / Decitabine Resistant Acute Myeloid Leukemia

Kotoko Yamatani, Tatsuro Watanabe, Kaori Saito, Abhishek Maiti, Satoshi Yamashita, Abdullah Khasawneh, Faith Jessica Paran, Kala Hayes, Gautam Borthakur, Joe R Harman, Shinya Kimura, Courtney D. DiNardo, Thomas A Milne, Michael Andreeff, Yoko Tabe, Marina Y. Konopleva
Journal: Blood
Blood (2023) 142 (Supplement 1): 4162.
https://doi.org/10.1182/blood-2023-178554
Published: 2023
Journal Articles

Azacitidine, Venetoclax and Allogeneic NK Cells in Newly Diagnosed Acute Myeloid Leukemia (ADVENT-AML): An Investigator-Initiated Multicenter Phase Ib Trial

Abhishek Maiti, Muharrem Muftuoglu, James J. Ignatz-Hoover, Courtney D. DiNardo, Farhad Ravandi, Michael Andreeff, Lianchun Xiao, Xuelin Huang, Keyur P. Patel, Jason B Litten, Eliot Bourk, Stephanie Astrow, Hagop M. Kantarjian, Ben K. Tomlinson, Naval Daver, David Wald
Journal: Blood
Blood (2023) 142 (Supplement 1): 4863.
https://doi.org/10.1182/blood-2023-182885
Published: 2023
Journal Articles

Outcomes of Patients (pts) with Newly Diagnosed Acute Myeloid Leukemia (AML) and TP53 mutation/Loss Treated on the Phase 2 Study of Venetoclax (Ven) Added to Alternating Cladribine (Clad) Plus Low-Dose Cytarabine (LDAC) and Azacitidine (Aza): A Subgroup Analysis

Jayastu Senapati, Sanam Loghavi, Patrick K Reville, Naval Daver, Gautam Borthakur, Courtney D. DiNardo, Elias Jabbour, Nicholas J. Short, Naveen Pemmaraju, Abhishek Maiti, Ghayas C. Issa, Uday R. Popat, Amin Alousi, Elizabeth J. Shpall, Koji Sasaki, Guillermo Garcia-Manero, Farhad Ravandi, Tapan M. Kadia
Journal: Blood
Blood (2023) 142 (Supplement 1): 4282.
https://doi.org/10.1182/blood-2023-179380
Published: 2023