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Volume 107, Issue 11

June 1 2006

In this Issue

INSIDE BLOOD
BLOOD WORK
PLENARY PAPERS
REVIEW ARTICLES
CHEMOKINES, CYTOKINES, AND INTERLEUKINS
CLINICAL TRIALS AND OBSERVATIONS
GENE THERAPY
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
PHAGOCYTES
TRANSPLANTATION
CORRESPONDENCE

INSIDE BLOOD

HEMOSTASIS

Annexin and APS: the clot thickens

Keith R. McCrae

View Articletitled, Annexin and APS: the clot thickens

RED CELLS

The less-traveled Fanconi road

Grover C. Bagby

View Articletitled, The less-traveled Fanconi road

NEOPLASIA

Is it time to stop treating subsets of DLBCL with R-CHOP?

Craig Moskowitz

View Articletitled, Is it time to stop treating subsets of DLBCL with R-CHOP?

HEMATOPOIESIS

Epo regulation: a 3-dimensional challenge

H. Franklin Bunn

View Articletitled, Epo regulation: a 3-dimensional challenge

HEMOSTASIS

GPVI: no magic bullet for thrombosis

Mark L. Kahn

View Articletitled, GPVI: no magic bullet for thrombosis

NEOPLASIA

Rush hour in AML: news on NPM traffic

Konstanze Döhner,Hartmut Döhner

View Articletitled, Rush hour in AML: news on NPM traffic

IMMUNOBIOLOGY

PI-3K controls B cells' sweet tooth

Laurence Morel

View Articletitled, PI-3K controls B cells' sweet tooth

HEMOSTASIS

Matrix rules: microfibrillar protein controls vascular development

Tatiana V. Byzova

View Articletitled, Matrix rules: microfibrillar protein controls vascular development

IMMUNOBIOLOGY

A tale of two T cells: suppressor CD8 T cells recalled to life

Edmund K. Waller

View Articletitled, A tale of two T cells: suppressor CD8 T cells recalled to life

BLOOD WORK

Rouleaux formation

View Articletitled, Rouleaux formation

PLENARY PAPERS

Prognostic significance of Bcl-6 protein expression in DLBCL treated with CHOP or R-CHOP: a prospective correlative study
Clinical Trials & Observations

Jane N. Winter,Edie A. Weller,Sandra J. Horning,Maryla Krajewska,Daina Variakojis,Thomas M. Habermann,Richard I. Fisher,Paul J. Kurtin,William R. Macon,Mukesh Chhanabhai,Raymond E. Felgar,Eric D. Hsi,L. Jeffrey Medeiros,James K. Weick,John C. Reed,Randy D. Gascoyne

View Articletitled, Prognostic significance of Bcl-6 protein expression in DLBCL treated with CHOP or R-CHOP: a prospective correlative study

REVIEW ARTICLES

Molecular basis of the diagnosis and treatment of polycythemia vera and essential thrombocythemia
Clinical Trials & Observations

Andrew I. Schafer

View Articletitled, Molecular basis of the diagnosis and treatment of polycythemia vera and essential thrombocythemia

Molecular pathogenesis of Fanconi anemia: recent progress
Clinical Trials & Observations

Toshiyasu Taniguchi,Alan D. D'Andrea

View Articletitled, Molecular pathogenesis of Fanconi anemia: recent progress

CHEMOKINES, CYTOKINES, AND INTERLEUKINS

Integrin inhibition through Lyn-dependent cross talk from CXCR4 chemokine receptors in normal human CD34⁺ marrow cells

Yuji Nakata,Brian Tomkowicz,Alan M. Gewirtz,Andrzej Ptasznik

View Articletitled, Integrin inhibition through Lyn-dependent cross talk from CXCR4 chemokine receptors in normal human CD34+ marrow cells

Deficiency in CCR5 but not CCR1 protects against neointima formation in atherosclerosis-prone mice: involvement of IL-10

Alma Zernecke,Elisa A. Liehn,Ji-Liang Gao,William A. Kuziel,Philip M. Murphy,Christian Weber

View Articletitled, Deficiency in CCR5 but not CCR1 protects against neointima formation in atherosclerosis-prone mice: involvement of IL-10

Supplemental data

CLINICAL TRIALS AND OBSERVATIONS

Up-regulation of asparagine synthetase expression is not linked to the clinical response l-asparaginase in pediatric acute lymphoblastic leukemia
Clinical Trials & Observations

Inge M. Appel,Monique L. den Boer,Jules P. P. Meijerink,Anjo J. P. Veerman,Nathalie C. M. Reniers,Rob Pieters

View Articletitled, Up-regulation of asparagine synthetase expression is not linked to the clinical response l-asparaginase in pediatric acute lymphoblastic leukemia

BCR-ABL mRNA levels at and after the time of a complete cytogenetic response (CCR) predict the duration of CCR in imatinib mesylate–treated patients with CML
Clinical Trials & Observations

Richard D. Press,Zac Love,Ashlie A. Tronnes,Rui Yang,Thuan Tran,Solange Mongoue-Tchokote,Motomi Mori,Michael J. Mauro,Michael W. Deininger,Brian J. Druker

View Articletitled, BCR-ABL mRNA levels at and after the time of a complete cytogenetic response (CCR) predict the duration of CCR in imatinib mesylate–treated patients with CML

GENE THERAPY

Proteasome activity restricts lentiviral gene transfer into hematopoietic stem cells and is down-regulated by cytokines that enhance transduction

Francesca Romana Santoni de Sio,Paolo Cascio,Anna Zingale,Mauro Gasparini,Luigi Naldini

View Articletitled, Proteasome activity restricts lentiviral gene transfer into hematopoietic stem cells and is down-regulated by cytokines that enhance transduction

Supplemental data

HEMATOPOIESIS

Rapid TNFR1-dependent lymphocyte depletion in vivo with a selective chemical inhibitor of IKKβ

Kumiko Nagashima,Vito G. Sasseville,Danyi Wen,Andrew Bielecki,Hua Yang,Chris Simpson,Ethan Grant,Michael Hepperle,Gerry Harriman,Bruce Jaffee,Tim Ocain,Yajun Xu,Christopher C. Fraser

View Articletitled, Rapid TNFR1-dependent lymphocyte depletion in vivo with a selective chemical inhibitor of IKKβ

Expression of Jak2V617F causes a polycythemia vera–like disease with associated myelofibrosis in a murine bone marrow transplant model

Gerlinde Wernig,Thomas Mercher,Rachel Okabe,Ross L. Levine,Benjamin H. Lee,D. Gary Gilliland

View Articletitled, Expression of Jak2V617F causes a polycythemia vera–like disease with associated myelofibrosis in a murine bone marrow transplant model

Supplemental data

Wilms tumor suppressor, Wt1, is a transcriptional activator of the erythropoietin gene

Christof Dame,Karin M. Kirschner,Katharina V. Bartz,Thomas Wallach,Christiane S. Hussels,Holger Scholz

View Articletitled, Wilms tumor suppressor, Wt1, is a transcriptional activator of the erythropoietin gene

Cul4A targets p27 for degradation and regulates proliferation, cell cycle exit, and differentiation during erythropoiesis

Binghui Li,Nan Jia,Reuben Kapur,Kristin T. Chun

View Articletitled, Cul4A targets p27 for degradation and regulates proliferation, cell cycle exit, and differentiation during erythropoiesis

A novel nonpeptidyl human c-Mpl activator stimulates human megakaryopoiesis and thrombopoiesis

Takanori Nakamura,Yoshitaka Miyakawa,Atsushi Miyamura,Akiko Yamane,Hidenori Suzuki,Mamoru Ito,Yasuyuki Ohnishi,Norihisa Ishiwata,Yasuo Ikeda,Nobutomo Tsuruzoe

View Articletitled, A novel nonpeptidyl human c-Mpl activator stimulates human megakaryopoiesis and thrombopoiesis

C/EBPα determines hematopoietic cell fate in multipotential progenitor cells by inhibiting erythroid differentiation and inducing myeloid differentiation

Hyung Chan Suh,John Gooya,Katie Renn,Alan D. Friedman,Peter F. Johnson,Jonathan R. Keller

View Articletitled, C/EBPα determines hematopoietic cell fate in multipotential progenitor cells by inhibiting erythroid differentiation and inducing myeloid differentiation

Genetic marking of hematopoietic stem and endothelial cells: identification of the Tmtsp gene encoding a novel cell surface protein with the thrombospondin-1 domain

Shin-ichiro Takayanagi,Takashi Hiroyama,Satoshi Yamazaki,Tomoko Nakajima,Yohei Morita,Joichi Usui,Koji Eto,Tsutomu Motohashi,Kensuke Shiomi,Kazuko Keino-Masu,Masayuki Masu,Yuichi Oike,Shigeo Mori,Nobuaki Yoshida,Atsushi Iwama,Hiromitsu Nakauchi

View Articletitled, Genetic marking of hematopoietic stem and endothelial cells: identification of the Tmtsp gene encoding a novel cell surface protein with the thrombospondin-1 domain

Supplemental data

STAT5-induced self-renewal and impaired myelopoiesis of human hematopoietic stem/progenitor cells involves down-modulation of C/EBPα

Albertus T. J. Wierenga,Hein Schepers,Malcolm A. S. Moore,Edo Vellenga,Jan Jacob Schuringa

View Articletitled, STAT5-induced self-renewal and impaired myelopoiesis of human hematopoietic stem/progenitor cells involves down-modulation of C/EBPα

Imatinib as a potential antiresorptive therapy for bone disease

Andrea L. Dewar,Amanda N. Farrugia,Mark R. Condina,L. Bik To,Timothy P. Hughes,Barrie Vernon-Roberts,Andrew C. W. Zannettino

View Articletitled, Imatinib as a potential antiresorptive therapy for bone disease

SHIP deficiency enhances HSC proliferation and survival but compromises homing and repopulation

Caroline Desponts,Amy L. Hazen,Kim H. T. Paraiso,William G. Kerr

View Articletitled, SHIP deficiency enhances HSC proliferation and survival but compromises homing and repopulation

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Thrombin overcomes the thrombosis defect associated with platelet GPVI/FcRγ deficiency

Pierre Mangin,Cindy L. Yap,Christelle Nonne,Sharelle A. Sturgeon,Isaac Goncalves,Yuping Yuan,Simone M. Schoenwaelder,Christine E. Wright,Francois Lanza,Shaun P. Jackson

View Articletitled, Thrombin overcomes the thrombosis defect associated with platelet GPVI/FcRγ deficiency

KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium

Rob J. Dekker,Reinier A. Boon,Mariska G. Rondaij,Astrid Kragt,Oscar L. Volger,Yvonne W. Elderkamp,Joost C. M. Meijers,Jan Voorberg,Hans Pannekoek,Anton J. G. Horrevoets

View Articletitled, KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium

Supplemental data

Functional analysis of zebrafish microfibril-associated glycoprotein-1 (Magp1) in vivo reveals roles for microfibrils in vascular development and function

Eleanor Chen,Jon D. Larson,Stephen C. Ekker

View Articletitled, Functional analysis of zebrafish microfibril-associated glycoprotein-1 (Magp1) in vivo reveals roles for microfibrils in vascular development and function

Supplemental data

Autoantibodies against the fibrinolytic receptor, annexin 2, in antiphospholipid syndrome
Clinical Trials & Observations

Gabriela Cesarman-Maus,Nina P. Ríos-Luna,Arunkumar B. Deora,Bihui Huang,Rosario Villa,Maria del Carmen Cravioto,Donato Alarcón-Segovia,Jorge Sánchez-Guerrero,Katherine A. Hajjar

View Articletitled, Autoantibodies against the fibrinolytic receptor, annexin 2, in antiphospholipid syndrome

Plasminogen inhibits TNFα-induced apoptosis in monocytes

Jennifer W. Mitchell,Nagyung Baik,Francis J. Castellino,Lindsey A. Miles

View Articletitled, Plasminogen inhibits TNFα-induced apoptosis in monocytes

hnRNP L regulates differences in expression of mouse integrin α2β1

Yann Cheli,Thomas J. Kunicki

View Articletitled, hnRNP L regulates differences in expression of mouse integrin α2β1

Platelet depletion in mice increases mortality after thermal injury

Satoshi Fujimi,Malcolm P. MacConmara,Adrian A. Maung,Yan Zang,John A. Mannick,James A. Lederer,Peter H. Lapchak

View Articletitled, Platelet depletion in mice increases mortality after thermal injury

IMMUNOBIOLOGY

Global transcriptional coactivators CREB-binding protein and p300 are highly essential collectively but not individually in peripheral B cells

Wu Xu,Tomofusa Fukuyama,Paul A. Ney,Demin Wang,Jerold Rehg,Kelli Boyd,Jan M. A. van Deursen,Paul K. Brindle

View Articletitled, Global transcriptional coactivators CREB-binding protein and p300 are highly essential collectively but not individually in peripheral B cells

Supplemental data

Interferon-λ–treated dendritic cells specifically induce proliferation of FOXP3-expressing suppressor T cells

Franck J. D. Mennechet,Gilles Uzé

View Articletitled, Interferon-λ–treated dendritic cells specifically induce proliferation of FOXP3-expressing suppressor T cells

Supplemental data

Foxp3⁺CD4⁺CD25⁺ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C

Tobias Manigold,Eui-Cheol Shin,Eishiro Mizukoshi,Kathleen Mihalik,Krishna K. Murthy,Charles M. Rice,Ciriaco A. Piccirillo,Barbara Rehermann

View Articletitled, Foxp3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C

Supplemental data

Epstein-Barr virus nuclear antigen 2 induces FcRH5 expression through CBF1

Joanne Mohan,Jessica Dement-Brown,Sabine Maier,Tomoko Ise,Bettina Kempkes,Mate Tolnay

View Articletitled, Epstein-Barr virus nuclear antigen 2 induces FcRH5 expression through CBF1

Wegener autoantigen induces maturation of dendritic cells and licenses them for Th1 priming via the protease-activated receptor-2 pathway

Elena Csernok,MaiXing Ai,Wolfgang L. Gross,Daniel Wicklein,Arnd Petersen,Buko Lindner,Peter Lamprecht,Julia U. Holle,Bernhard Hellmich

View Articletitled, Wegener autoantigen induces maturation of dendritic cells and licenses them for Th1 priming via the protease-activated receptor-2 pathway

Uncoupling of T-cell effector functions by inhibitory killer immunoglobulin–like receptors

Gabriella Henel,Karnail Singh,Dapeng Cui,Sergey Pryshchep,Won-Woo Lee,Cornelia M. Weyand,Jörg J. Goronzy

View Articletitled, Uncoupling of T-cell effector functions by inhibitory killer immunoglobulin–like receptors

Supplemental data

Antigen receptor–mediated changes in glucose metabolism in B lymphocytes: role of phosphatidylinositol 3-kinase signaling in the glycolytic control of growth

Cheryl A. Doughty,Blair F. Bleiman,Dean J. Wagner,Fay J. Dufort,Jennifer M. Mataraza,Mary F. Roberts,Thomas C. Chiles

View Articletitled, Antigen receptor–mediated changes in glucose metabolism in B lymphocytes: role of phosphatidylinositol 3-kinase signaling in the glycolytic control of growth

Efficient inhibition of HIV-1 replication in human immature monocyte-derived dendritic cells by purified anti–HIV-1 IgG without induction of maturation

Vincent Holl,Maryse Peressin,Sylvie Schmidt,Thomas Decoville,Susan Zolla-Pazner,Anne-Marie Aubertin,Christiane Moog

View Articletitled, Efficient inhibition of HIV-1 replication in human immature monocyte-derived dendritic cells by purified anti–HIV-1 IgG without induction of maturation

Cytokine-induced IL-10–secreting CD8 T cells represent a phenotypically distinct suppressor T-cell lineage

Alistair Noble,Angela Giorgini,Jamie A. Leggat

View Articletitled, Cytokine-induced IL-10–secreting CD8 T cells represent a phenotypically distinct suppressor T-cell lineage

NEOPLASIA

Oncogenic RAS mutations in myeloma cells selectively induce cox-2 expression, which participates in enhanced adhesion to fibronectin and chemoresistance

Bao Hoang,Li Zhu,Yijiang Shi,Patrick Frost,Huajun Yan,Sanjai Sharma,Sherven Sharma,Lee Goodglick,Steven Dubinett,Alan Lichtenstein

View Articletitled, Oncogenic RAS mutations in myeloma cells selectively induce cox-2 expression, which participates in enhanced adhesion to fibronectin and chemoresistance

Requirement of the human T-cell leukemia virus (HTLV-1) tax-stimulated HIAP-1 gene for the survival of transformed lymphocytes

Katja Wäldele,Katrin Silbermann,Grit Schneider,Tobias Ruckes,Bryan R. Cullen,Ralph Grassmann

View Articletitled, Requirement of the human T-cell leukemia virus (HTLV-1) tax-stimulated HIAP-1 gene for the survival of transformed lymphocytes

Identification of subtype-specific genomic alterations in aggressive adult T-cell leukemia/lymphoma

Aya Oshiro,Hiroyuki Tagawa,Koichi Ohshima,Kennosuke Karube,Naokuni Uike,Yukie Tashiro,Atae Utsunomiya,Masato Masuda,Nobuyuki Takasu,Shigeo Nakamura,Yasuo Morishima,Masao Seto

View Articletitled, Identification of subtype-specific genomic alterations in aggressive adult T-cell leukemia/lymphoma

Supplemental data

Prospective analysis of TEL/AML1-positive patients treated on Dana-Farber Cancer Institute Consortium Protocol 95-01
Clinical Trials & Observations

Mignon L. Loh,Meredith A. Goldwasser,Lewis B. Silverman,Wing-Man Poon,Shashaank Vattikuti,Angelo Cardoso,Donna S. Neuberg,Kevin M. Shannon,Stephen E. Sallan,D. Gary Gilliland

View Articletitled, Prospective analysis of TEL/AML1-positive patients treated on Dana-Farber Cancer Institute Consortium Protocol 95-01

Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc⁺ AML

Brunangelo Falini,Niccolò Bolli,Jing Shan,Maria Paola Martelli,Arcangelo Liso,Alessandra Pucciarini,Barbara Bigerna,Laura Pasqualucci,Roberta Mannucci,Roberto Rosati,Paolo Gorello,Daniela Diverio,Giovanni Roti,Enrico Tiacci,Giovanni Cazzaniga,Andrea Biondi,Suzanne Schnittger,Torsten Haferlach,Wolfgang Hiddemann,Massimo F. Martelli,Wei Gu,Cristina Mecucci,Ildo Nicoletti

View Articletitled, Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML

Supplemental data

Cytochrome c–related caspase-3 activation determines treatment response and relapse in childhood precursor B-cell ALL
Clinical Trials & Observations

Lüder Hinrich Meyer,Leonid Karawajew,Martin Schrappe,Wolf-Dieter Ludwig,Klaus-Michael Debatin,Karsten Stahnke

View Articletitled, Cytochrome c–related caspase-3 activation determines treatment response and relapse in childhood precursor B-cell ALL

Supplemental data

Dasatinib (BMS-354825) targets an earlier progenitor population than imatinib in primary CML but does not eliminate the quiescent fraction

Mhairi Copland,Ashley Hamilton,Lucy J. Elrick,Janet W. Baird,Elaine K. Allan,Niove Jordanides,Martin Barow,Joanne C. Mountford,Tessa L. Holyoake

View Articletitled, Dasatinib (BMS-354825) targets an earlier progenitor population than imatinib in primary CML but does not eliminate the quiescent fraction

Constitutive NF-κB and NFAT activation leads to stimulation of the BLyS survival pathway in aggressive B-cell lymphomas

Lingchen Fu,Yen-Chiu Lin-Lee,Lan V. Pham,Archito Tamayo,Linda Yoshimura,Richard J. Ford

View Articletitled, Constitutive NF-κB and NFAT activation leads to stimulation of the BLyS survival pathway in aggressive B-cell lymphomas

MEK1 inhibition sensitizes primary acute myelogenous leukemia to arsenic trioxide–induced apoptosis

Paolo Lunghi,Antonio Costanzo,Luigi Salvatore,Nelida Noguera,Laura Mazzera,Antonio Tabilio,Francesco Lo-Coco,Massimo Levrero,Antonio Bonati

View Articletitled, MEK1 inhibition sensitizes primary acute myelogenous leukemia to arsenic trioxide–induced apoptosis

PHAGOCYTES

Protein-tyrosine kinase Syk is required for pathogen engulfment in complement-mediated phagocytosis

Yuhong Shi,Yumi Tohyama,Tomomi Kadono,Jinsong He,S. M. Shahjahan Miah,Ryoichi Hazama,Chisato Tanaka,Kaoru Tohyama,Hirohei Yamamura

View Articletitled, Protein-tyrosine kinase Syk is required for pathogen engulfment in complement-mediated phagocytosis

TRANSPLANTATION

Clinical significance of minimal residual disease, as assessed by different techniques, after stem cell transplantation for chronic lymphocytic leukemia
Clinical Trials & Observations

Carol Moreno,Neus Villamor,Dolors Colomer,Jordi Esteve,Eva Giné,Ana Muntañola,Elias Campo,Francesc Bosch,Emili Montserrat

View Articletitled, Clinical significance of minimal residual disease, as assessed by different techniques, after stem cell transplantation for chronic lymphocytic leukemia

CORRESPONDENCE

Maintenance of HCV-specific T-cell responses in antibody-deficient patients a decade after early therapy

Nasser Semmo,Michaela Lucas,George Krashias,Georg Lauer,Helen Chapel,Paul Klenerman

View Articletitled, Maintenance of HCV-specific T-cell responses in antibody-deficient patients a decade after early therapy

Complete regression of cutaneous lesions of refractory Ph+ ALL after 4 weeks of treatment with BMS-354825

Elisabetta Abruzzese,Giovanni Del Poeta,Rosanna Barbato,Stefano Fratoni,Malgorzata M. Trawinska,Daniela Zangrilli,Angela M. Coletta,Ivona M. Patroi,Francesca Francesconi,Giuseppe Santeusanio,Paolo De Fabritiis,Sergio Amadori

View Articletitled, Complete regression of cutaneous lesions of refractory Ph+ ALL after 4 weeks of treatment with BMS-354825

Discordant distribution of JAK2V617F mutation in siblings with familial myeloproliferative disorders

Animesh Pardanani,Terra Lasho,Rebecca McClure,Martha Lacy,Ayalew Tefferi

View Articletitled, Discordant distribution of JAK2V617F mutation in siblings with familial myeloproliferative disorders

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Issue Archive

Table of Contents

INSIDE BLOOD

BLOOD WORK

PLENARY PAPERS

Prognostic significance of Bcl-6 protein expression in DLBCL treated with CHOP or R-CHOP: a prospective correlative study Clinical Trials & Observations

REVIEW ARTICLES

Molecular basis of the diagnosis and treatment of polycythemia vera and essential thrombocythemia Clinical Trials & Observations

Molecular pathogenesis of Fanconi anemia: recent progress Clinical Trials & Observations

CHEMOKINES, CYTOKINES, AND INTERLEUKINS

CLINICAL TRIALS AND OBSERVATIONS

Up-regulation of asparagine synthetase expression is not linked to the clinical response l-asparaginase in pediatric acute lymphoblastic leukemia Clinical Trials & Observations

BCR-ABL mRNA levels at and after the time of a complete cytogenetic response (CCR) predict the duration of CCR in imatinib mesylate–treated patients with CML Clinical Trials & Observations

GENE THERAPY

HEMATOPOIESIS

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Autoantibodies against the fibrinolytic receptor, annexin 2, in antiphospholipid syndrome Clinical Trials & Observations

IMMUNOBIOLOGY

NEOPLASIA

Prospective analysis of TEL/AML1-positive patients treated on Dana-Farber Cancer Institute Consortium Protocol 95-01 Clinical Trials & Observations

Cytochrome c–related caspase-3 activation determines treatment response and relapse in childhood precursor B-cell ALL Clinical Trials & Observations

PHAGOCYTES

TRANSPLANTATION

Clinical significance of minimal residual disease, as assessed by different techniques, after stem cell transplantation for chronic lymphocytic leukemia Clinical Trials & Observations

CORRESPONDENCE

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American Society of Hematology

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Prognostic significance of Bcl-6 protein expression in DLBCL treated with CHOP or R-CHOP: a prospective correlative study
Clinical Trials & Observations

Molecular basis of the diagnosis and treatment of polycythemia vera and essential thrombocythemia
Clinical Trials & Observations

Molecular pathogenesis of Fanconi anemia: recent progress
Clinical Trials & Observations

Up-regulation of asparagine synthetase expression is not linked to the clinical response l-asparaginase in pediatric acute lymphoblastic leukemia
Clinical Trials & Observations

BCR-ABL mRNA levels at and after the time of a complete cytogenetic response (CCR) predict the duration of CCR in imatinib mesylate–treated patients with CML
Clinical Trials & Observations

Autoantibodies against the fibrinolytic receptor, annexin 2, in antiphospholipid syndrome
Clinical Trials & Observations

Prospective analysis of TEL/AML1-positive patients treated on Dana-Farber Cancer Institute Consortium Protocol 95-01
Clinical Trials & Observations

Cytochrome c–related caspase-3 activation determines treatment response and relapse in childhood precursor B-cell ALL
Clinical Trials & Observations

Clinical significance of minimal residual disease, as assessed by different techniques, after stem cell transplantation for chronic lymphocytic leukemia
Clinical Trials & Observations